4-Chloro-α-(4-chlorophenyl)-α-(trichloromethyl) Benzyl Alcohol(Dicofol)의 各種有機溶媒中에서의 安定性

申鉉和,洪鍾旭 한국응용생명화학회 1982 Applied Biological Chemistry (Appl Biol Chem) Vol.25 No.3

Dicofol의 各種 有機溶媒에 對한 安定性을 調査하기 위하여 -5℃에서 7日間 放置하여 그 沈搬生成有無를 調査하고, 50℃에서 56日間 處理한 다음 各種溶媒에 對해서 Dicofol의 分解形態를 T.L.C.로 確認하였으며, 그 主成分 分解率을 2週간격으로 ga5 chromatography로 測定하였다. 그 結果 Dicofol 水和劑와 N.N-dimethyiformamide 및 cyclohexanone 溶液에서는 Dicofol의 主成分 分解率이 各各 1.2%, 6.7%, 13.3%이었으나 xylene, touluene, M.I.B.K. 및 isophorone 溶液에서는 沈澱이 生成되어 Dicofol의 溶劑로서는 적합하지 못하였다. 이러한 事實로 미루어 볼 때 供試된 各種 有機溶媒中에서 Dicofol의 製濟上 가장 적합한 溶媒는 isophorone 임을 알았다. This experiment was carried out to investigate the stability of Dicofol solutions which were prepared with various organic solvents such as xylene, toluene, methylisobutyl ketone (H.I.B.K.), cyclohexanone, N.N.-dimetyl formamide (N.N.-D.M.F.) and isophorone under different temperature and storage period. The decomposition rate of Dicofol was increased in the order of cyclohexanone> N.N.-D.M.F.>W.P.>toluene, xylene, M.I.B.K. and isophorone. However, it was shown that precipitation was found in Dicofol solutions such as xylene, toluene and M.I..B.K. except isophorone. Therefore, isophrrone was recognized as the best of organic solvents tested for Dicofol in the case of emulsifiable concentrate formulation with it.

응급실을 내원한 구강악안면외과 안면골 골절 환자의 변화에 대한 비교 연구

신상훈,성화식,강영훈,황대석,김용덕,김욱규,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.24

Although there have been many clinical studies about the facial trauma in the recent as well as in the past, severity and frequency of facial trauma are reported multifarious. It seemed to be because of variety of social, cultural, and environmental factors, and the view point of investigators. In this study, we investigated about the patients visiting emergency room during recent 4 years(2004-2007), and compared with retrospective study during former 10 years(1992-1996, 1999-2003) in Dept. OMS Pusan National University Hospital. We assessed the cause, type, demographic, etc, and analyzed alterations of facial bone fractures during past 3 periods. The results were as follows. The total number of patients was increased. 429 patients treated for maxillofacial fractures between January 1992 and December 1996, 466 patients treated between January 1992 and December 1996 and 764 patients treated between January 2004 and December 2007. The male-to-female ratio were 4.6:1, 3.9:1, and 4.16:1, respectively. Patient in the age groups of 10-19 years and 20-29 years increased in the latter two periods. Assaults and falls are decreased gradually, but slip down s are increased. Traffic accidents are still major cause of facial trauma. The mandibular fractures showed the highest incidence thorought three periods. Symphysis fractures of mandible was increased and condyle fractures of mandible was drecreased in the third period.

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

Multibit Recoding 기법과 Redundant Binary 연산을 이용한 병렬 승산기 설계

박종화,신경욱 금오공과대학교 산업기술개발연구원 2000 産業技術開發硏究 Vol.16 No.-

Proposed in this paper is a new algorithm for designing parallel multiplier, which is based on radix-8 Booth recoding and redundant binary (RB) representation of partial products. When compared to the conventional modified Booth algorithm, it reduces the number of partial products to be added by one third at the expense of an additional addition step for multiple generation. It has only [N/6]RB partial products for a N-b binary multiplication. To demonstrate the proposed approach, a 32-b x 32-b parallel multiplier has been designed using VHDL modeling and logic synthesis. The proposed multiplication scheme can be applied to the design of high-performance multiplier cores for floating-point unit (FPU) and general-purpose digital signal processors.

감의 脫澁處理中 Pectin 含量과 Texture의 變化

崔鍾旭,孫泰華,鄭信敎,李吉雨,姜峻洙 慶北大學校 1989 論文集 Vol.47 No.-

This experiment was made to investigate the changes of the contents of acetaldehyde, alcohol, tannin, and to study the texture changes of persimmon in relation to the contents of pection during the removal of astringency by CO_2. 1. During the removal of astringency of persimmon fruits, the contents of soluble tannin showed the rapid decrease in high concentration of CO_2, but the contents of ethanol and acetaldehyde showed the rapid increase in all treatments. 2. The contents of W.S.P. increased, but H.S.P. decreased in all treatments. 3. All texture paramenters of persimmon fruits except springness and adhesiveness were decreased druing the removal of astringency. 4. The contents of W.S.P. were good correlated with the changes of hardness in all treatments.

DSP 응용을 위한 작은 오차의 절사형 Booth 승산기 설계

박종화,신경욱 金烏工科大學校 2000 論文集 Vol.21 No.-

The paper describes a design of low-error truncated Booth multiplier for digital signal processing(DSP) applications. Given two N-bit inputs, the truncated multiplier generates N bits (instead of 2N bits) product by eliminating the N least-significant bits of product. The truncation of product to N bits is achieved by omitting about half the partial product generator and adders, but a significant truncation error is introduced in the resulting product. To keep the truncation error to a minimum, an efficient carry-generating circuit is devised, which feeds the revising information to the carry inputs of the retained partial product adders. When compared with non-truncated parallel multiplier, the truncated multiplier reduces about 35%~40% of the chip area. Error analysis shows that the proposed approach has lower error than other fixed-width multipliers and is cost-effective. As a result, the truncated multiplier is suitable for an area-efficient and low-power implementation of multimedia and DSP functions.

젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

효율적인 단정도/배정도 승산을 위한 이중모드 승산기

박종화,이종남,신경욱 金烏工科大學校 1999 論文集 Vol.20 No.-

High-speed/low-power/low-cost multipliers play an important role in micro-processors and digital signal processors because multiplier core not only occupies a signigicant percentage of the silicon area, but also limits the overall performance. This paper describes a design of dual mode multiplier (DMM) that performs single- and double-precision multiplications using hardware required for single-precision multiplication. We propose an efficient algorithm which partitions a double-precision multiplication into four single-precision sub-multiplications and then computes them with sequential accumulations. When compared with conventional double-precision multipliers, our approach reduces hardware complexity required for double-precision multiplication by about one third at the expense of increased latency. The DMM has been designed using a 0.25-㎛ 5-metal CMOS technology, and contains about 25,000 transistors on the area of about 0.77×0.40㎟. The HSPICE simulation results show that the DMM core can safely operate with 150-MHz clock at 2.5-V, and the estimated power dissipation is about 110-mW at double-precision mode.

林業稅制에 關한 考察 : 韓國, 日本, 美國의 制度에 대하여

金知洪,辛在萬,尹鐘和 江原大學校 森林科學硏究所 1985 Journal of Forest Science Vol.5 No.-

Introduced with a review of general taxation principles in Korea, the article provides details of the main type of tax related to forest resource management. The forest taxation of Japan and the United states is also examined to compare with the Korean legislation. The basic analysis is made upon provisions and interpretation of each tax, its history, and its influence on forest management. For Korean forest taxation, some points to be considered are as follows. 1) Since 500,000 won of special income tax deduction from total forest revenue is not likely to be remaining with its absolute value, it should be variable by socio-economic situation. 2) Income tax exemption from newly reforested land for 40 years may shorten rotation and induce heavy harvest cutting for long-term commercial timber species. 3) With a few exceptions, general forest managers are not offered favors in death tax and property tax for their forest land. Taxes have frequently been called the primary impediment factor for timber production because the effectiveness of incentives of programs has not been provided. Considered to the specific characteristics of forestry and resource conservation, Korean forest taxation should be revised and complemented to encourage forest management or maintenance.

압저항형 스마트 실리콘 압력 센서의 설계

정후민,신윤권,조상복,이종화 울산대학교 2001 공학연구논문집 Vol.32 No.2

압저항형 스마트 실리콘 압력 센서를 0.6 ㎛ 이중 폴리 실리콘 이중 금속 CMOS 공정으로 구현하기 위하여 설계하였다. 이 스마트 실리콘 압력 센서는 압저항형 저항기들로 된 휘스톤 브리지를 갖는 다이아프램과 op-amp, A/D 변환기, 및 UART 회로 등의 주변회로 들로 구성되어 있다. 브리지 회로의 출력 전압과 압력에 의한 기계적 응력 사이의 관계를 COSMOS-M 상용프로그램으로 다이아프램의 응력 분포를 모의실험하여, 압저항기의 최적의 위치와 크기에 대한 연구를 하였다. CMOS op-amp 회로는 규정된 출력 특성을 얻기 위하여 크기가 다른 트랜지스터들로 설계하여 HSPICE로 모의실험하여 최적화 시켰다. A/D 변화기 회로는 가능한 칩 면적을 줄이기 위하여 서브 레인징 기법과 신경 MOSFET 구조를 이용하여 설계하였다. UART회로는 VHDL 소스 코드와 셀 라이브러리를 이용하고 Synopsys로 합성하여 설계하였다. 회로의 물리적 레이아우트 설계는 Mentor 틀로 설계하였다. 그러나 온도보상회로와 출력오프셋 문제는 아직 해결하지 못하고 다음에 연구할 예정이다. A piezoresistive smart silicon pressure sensor is designed to implement with 0.6 ㎛ double-polysilicon double-metal CMOS precess. This smart pressure sensor is composed of a diaphragm with piezoresistive resistors' Wheatstone bridge and the peripheral circuitry of op-amp, A/D converter and UART. The relationship between the output voltage of the bridge circuit and the mechanical stress by applied pressure was studied by simulating the stress distribution on the diaphragm with COSMOS-M package program to optimize the size and position of piezoresistors. The CMOS op-amp circuit was designed with different CMOS transistor sizes to obtain the defined op-amp output characteristics and simulated with HSPICE. The A/D converter was designed using neuron MOSFET structure and sub-ranging method to minimize the chip area. The UART circuit was designed by using VHDL source code and cell library and by synthesizing with Synopses and the physical layout of the circuit was designed with Mentor tools. The problems for temperature compensation and the output voltage offset were not yet considered.