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유년기 안구적출술 및 방사선치료로 인하여 발생된 안와 열성장에 대한 재건 치험례
홍관석,김성문,김훈,임재석,최미숙,최성원,권종진 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1
There are many reports of the surgical management for the craniofacial abnormalities arising from the irradiation of the head and face for treatment of childhood cancers. Since the mordern combined-modality theraphy for childhood cancers began in the late 1960s and the early 1970s, recent reports have described the occular, dental and maxillo-facial abnormalities after irradiation in long-term survivors of cancers of the head and face. The resultant deformities may be known to be difficult to reconstruct with surgical techniques. This paper describes the late reconstructive surgery for the unilateral orbital and malar hypoplasia after eyeball enucleation and irradiation during childhood to correct the facial asymmetry and expand the contracted orbital socket into the functional dimension for the retaining eyeball prosthesis with spherical implant. We reports the satisfactory preliminary results from the midfacial osteotomy through the supero-lateral orbital rim and malar bone and the antero-lateral repositioning with the autogenous bone grafting in 26 year-old female patient who will be planned to make the new eyeball prosthesis by the department of ophthalmology.
지속적 및 간헐적 가압력이 치주인대 배양세포의 Alkaline Phosphatase 활성도에 미치는 영향
성재현,경희문,배성민,권숙이 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.4
지속적 및 간헐적인 가압력이 배양치주인대 세포의 ALP활성도에 미치는 영향을 알아보기 위하여 치주인대세포를 24 well 배양접시에 배양한 후 밀생상태가 되었을 때, 세포배양기 속의 특수제작된 사각상자에 배양접시를 넣은 후 실험기간동안 300g/㎠의 압력을 10분간 가압시킨 후 10분간 가압이 중지되도록 한 간헐적 가압군, 그리고 압력을 가하지 않은 군을 대조군으로 하여 각각 실험 24시간, 72시간 후의 alkaline phosphatase의 활성도를 측정하여 다음과 같은 결과를 얻었다. 1. 가압 24시간 군에서는 간헐적 가압군이 대조군에 비하여 ALP활성도가 낮게 나타났다(p>0.05). 2. 가압 48시간 군에서는 실험군은 대조군에 비하여 ALP활성도에 유의한 차이는 나타나지 않았다. 3. 가압 72시간 군에서는 지속적 가압군이 대조군에 비하여 ALP활성도가 높게 나타났다(p>0.01). The purpose of this study was to evaluate the effect of cellular activity on PDL cells dependent on intermittent and continuous compressive force by determining the alkaline phosphatase activity. An intermittent and continuous compressive force were applied on PDL cells at the confluent stage. The alkaline phosphatase activity was measured on control and experimental groups every 24, 48, 72hours. The experimental group were consist of continuous and intermittent compressive group which were compressed by 300g/㎠ of diaphram pump. The intermittent compressive group was connected by timer which was worked on 10 minutes and off 10minutes. The results were as follows; 1. The alkaline Phosphatase activity of intermittent compressive group was lower than control at 24 hours(p>0.05). 2. The alkaline Phosphatase activity between each groups showed no significant differences at 48hours. 3. The alkaline Phosphatase activity of continuous compressive group was significantly higher than control group at 72 hours(p>0.01).
Harvold activator의 효과에 관한 임상적 고찰
성재현,김광석 慶北大學校 齒科大學 1986 慶北齒大論文集 Vol.3 No.1
저자는 기능적 장애요인이 있는 상악 전치부 돌출을 주소로 내원한 환자 2명을 Harvold activator 로 치료하였다. 치료전후 두부방사 선규격사진을 분석 검토한 결과를 다음과 같이 요약할 수 있었다. 1. 하악골 전방성장 촉진으로 ∠ANB 의 감소가 있었다. 2. 상하악 제 1 대구치의 전방이동 및 정출이 있었으며 특히 하악에서 현저함을 보여 구치관계 개선에 도움이 되었다. 3. 상악전치는 설측경사 및 후방이동이 약간 있었다. 4. 하악전치는 전방이동은 많았지만 경사도는 거의 변화하지 않았다. The authors treated two patients by Harvold activator who chiefly complained the maxillary anterior protrusion. Analyzing the lateral cephalometric radiograph before and after treatment, the authors obtained following results. 1. Because of mandibular forward growth acceleration, ANB angle decreased. 2. Because of mesial movement and extrusion of upper and lower 1st molar especially lower 1st molar, molar relationship was improved 3. There were a certain degree of lingual tipping and backward movement of upper incisors. 4. Although there was a lot of forward movement of lower incisors, there was little change in tipping of lower incisors.
란크릭 캅셀(플루옥세틴 20mg)에 대한 프로작 캅셀의 생물학적 동등성 시험
심상범,조요나,오한석,류재환,이경태,김남재,서성훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-
Bioequivalence of two flouxetine capsule, ProzacR (Lilly kora Ltd.) and LanclicR (Samsung Pharm. IND. Co.), was evalated according to the guideline of KFDA. Twenty four healthy male volunteers (21-26 years old) were divided into two groups and a randomized 2×2 cross-over study was employed. After 60mg of fluoxetine was orally administered, blood was taken at 1, 2, 3, 4, 5, 6, 7, 8, 10, 12, 24, 32, 48 and 72 hours after administration and just before administration. Plasma was analyzed for fluoxetine and internal standard (clomipramine) by a sensitive and validated HPLC assay. The pharmaco kinetic parameters (AUCt, Cmax and Tmax) wre calculated and ANOVA test was used for the statistical analysis of parameters. Differences in (AUCt, Cmax and Tmax between two capsules were -0.90, 3.46 and -14.08% respectively. All powers (1-β) for AUGt, Cmax and Tmax were more than 0.9. Detectable differences (Δ) and confidence interval were all less than ±20%. All the parameters above met the criteria of KFDA for bioequivalence and indicated that LanclicR capsules are bioequivalent to ProzacR capsules.
Pd 촉매하에서 유기주석 화합물과 Iodane 화합물의 Cross-Coupling 반응에 관한 연구
강석구,이홍우,김재선,최상철 성균관대학교 기초과학연구소 1996 論文集 Vol.47 No.1
The palladium-catalyzed coupling of organostannanes with iodanes(Koser's and Zefirov's reagents) in the presence of palladium catalyst was accomplished at room temperature under aqueous conditions to afford phenyl- or 4-iodophenyl-substituted products depending on the iodanes used.
鄭在奎,李相準,文榮石 慶北大學校 1964 論文集 Vol.8 No.-
In order to observe the appearance of drug resistant strains in vivo, soil acid fast bacilli (s-12) which exhibited and appearance in high frequency of drug resistant strains in vitro experiments, were inoculated into the mice, and three days after inoculation these mice were followed by treatment with streptomycin and isonicotinic amide hydrazid for 2 to 3 weeks according to the groups. After the cessation of treatment, mice of the each group were sacrificed and the drugs treated, on both two and three weeks treated groups, with a single exception of high druges treated, on both and three weeks treated groups, with a single exception of high resistant variant from on the liver lesion of the 3 weeks treated isonicotnic amid hydrazid group.
한글ㆍ영문 겸용 Word Processor System 개발에 관한 연구
이상인,강석건,서창렬,신태민,박규태,여재준,장이한 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.2
The design theory and implementation of a word processor system with more efficient processing of Korean and English text are studied. A screen editing method is implemented which is more flexible to handle the texts. Convinient control of the keyboards, cursors moving, texts editing, line marking and block operations are considered. The codes to avoid the complexity and inefficiency which are caused by difference of the code length between the Korean and English characters are reconstructed. File management systems and algorithms for executing the control commands are also studied. As a result, a successful word processor system is designed and implemental which performs a complete screen editing system. The performance of the system includes flexible cursor movement, margin setting, block operations of insertion, deletion and copying any sizes of the line and blocks; and also, the printout routines for size variation of the characters are worked out.
강석구,조현성,이재호 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.2
천연물 합성에서 출발물질로 유용하게 쓰이는 디아세톤 글루코스 헥소퓨라노스고리의 산화와 입체선택적 변형에 관하여 연구하였다. 이 고리의 C-3위치에 있는 히드록시기를 Trifluoroacetic anhydride(TFAA)로 사용하여 케토기로 산화시키는 방법을 연구한 후 얻어진 C-3 위치에 케톤에 대해 Grignard반응과 Wittig반응을 도입하여 퓨라노스고리의 C-3위치에 입체 선택적으로 치환기를 유도하는 방법을 연구하였다. 또한 고리밖의 곁가지의 변형도 아울러 연구하였다. We have studied on the oxidation and the stereoselective modifications of the hexofuranose ring derived from diacetone glucose. We have attempted the method of the oxidation with trifluoroacetic anhydride (TFAA) on the C-3 position of this furanose ring. On the other hand, we have induced the stereoselective substrate on the keto group of the C-3 position. The modifications of the side chain out of the ring have been also studied.