The Phase II Clinical study of Rebamipide(Mucosta Tablet) on Chronic Glomerulonephritis Patients

Chin, H. J 大韓臨床藥理學會 1997 臨床藥理學會誌 Vol.5 No.2

암환자에서 단구매개 세포파괴능과 혈청내 Sialic acid농도

승기배,이흥현,서재열,문한림,진종률,박종원,김춘추,김동집 大韓血液學會 1984 大韓血液學會誌 Vol.19 No.1

비양자성 용매 속에서 트리플루오로에틸클로라이드와 알칼리금속을 이용한 트리플루오로에탄올의 합성

김경환,이현주,김훈식,김홍곤,진종식 한국공업화학회 2002 응용화학 Vol.6 No.2

Preparation of 2,2,2-trifluoroethanol from 1,1,1-trifluoroethylchloride with alkali-metals in aprotic polar solvents has been studied. Effects of alkali-metals and solvents on the 2,2,2-trifluoroethanol yield as well as the reaction mechanism were investigated. 2,2,2-trifluoroethanol was produced at high temperatures between 150℃ and 250℃. CH_3COOK produced better yields than KOH, and the co-solvent system of v -butyrolactone and ionic liquid [BMIM]^+BF_4^- produced remarkably improved results.

칸디다증의 면역진단 방법 비교 연구(Ⅱ)

김봉수,김현경,이영선,조인선,동미란,유미옥,오현순,김동한,신종희 국립보건연구원 1994 국립보건원보 Vol.31 No.1

Dodeyl diamino thyi glycin hydrochloride(Hygien 51)의 각종항산균에 대한 항균작용에 관한 시험관내 실험

황청자,진재신,김주덕,오흥근 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1

In order to prevent cross-infection, the sterilization of used and/or contaminated anesthetic- apparatus is still a difficult problem in clinical practice, particularly, following anesthesia for known advanced pulmonary tuberculosis cases. Therefore the antibacterisl activities of, an amphoteric detergent, Dodecyl diaminoethyl glycin hydrochloride (Hygien 51) were tested in vitro as a disinfectant against mycobacteria (M. tuberculosis H37 Rv, M. bovis, M. avium, M. tuberculosis H37 Ra, M. phlei, B.C.G.) The antimycobacterial activity tests were perfomed according to the modified Kolmer method. The testing organisms were cultured in Dubos broth at 37°C, and the detergent, Hygien 51, was: diluted with sterile distilled water to 1,3,5 and 10%. One half milliliter of culture was pipetted into each tube containing 4.5 ml of diluted detergent, and at intervals of 3, 15, 30, 60, 120, 180 and 240 minutes, a 4mm loopful of the material was removed from each tube, and transferred to Ogawa media. The tests were carrid out at two different temperatures, 20°C and 50°C. The subcultures were incubated at 37°C for more than 8 weeks. The results were obtained as follows: 1) At room temperature (20°C), all mycobateria, except M. bovis, were destroyed by treatment- with 10% solution of the detergent for more than 60 minutes. M. bovis was relatively sensitive to the detergent, and was killed by 5% solution for 30 min. and 10% for 15 min., but M. avium. was very resistant, and was not killed by 10% solution for 240 min. 2) By treatment with the detergent at 50°C, the antimycobacterial activities of the detergent were highly increased. All mycobacteria were destroyed by 1% solution for 180 min, and by 10% for less than 30 min at 50°C. In the comparison of the antibacterial activities against mycobacteria and other bacteria, it shows that mycobacteria are generally more resistant to the detergent, Hygien 51.

내시경적 초음파촬영술로 위치가 확인된 인슐린종 1 예

김기수,박성우,이기업,이인철,진재용,이철환,강재영,김해련,한덕종 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.2

Insulinomas are tumors that, in more than 90% or cases, are both single and benign, so the potential for surgical cure is very high. But, their localization is somewhat difficult, as they are small in size and located deep in pancreatic parenchyma. Because success of operation is depentdent on the localization rather than the surgical techniques, the availability of good licalization technique is mandatory. Recently, endoscopic ultrasonography(EUS) has been reported to be a very sensitive and specific test for the localization of insulinomas. We report a case of insulinoma that was localized successfully by EUS, after failure in localization by abdominal ultrasonography, abdominal CT, selective angiography, and even by transhepatic portal vein sampling. (J Kor Soc Endocrinol 8:197~202, 1993)

요도하열을 동반한 남성반음양 1례 보고

진한식,유재덕,신극선,오석준 大韓成形外科學會 1979 Archives of Plastic Surgery Vol.6 No.1

Male hermaphroditism may be defined as a process of incomplete masculinization of the internal or external genital organs or both in subjects with male gonads and male sex chromatic distribution. In the differential diagnosis of genital ambiguity, the important points include history, physical examination. sex chromatin pattern, and determination of the urinary steriod excretion pattern, and also, of help in selected cases are endoscopy, X-ray contrast studies, laparotomy with gonadal biopsy and chromosomal analysis. Cases of male hermaphroditism with ambiguous external genitals can be devided into those with absence of breast development which are usually called PPSH(Pseudovaginal Perineoscrotal Hypospadia) and those with breast development which are usually called incomplete or partial testicular feminization. The former is characterized by a phallus of intermediate size and a perineal urethral meatus, and blindly ending "vagina" which may poen either into the urethra or the perineum. A labia majora-like cleft scrotum frequently contains normally developed testes, and Wolffian-duct derivatives show normal male differentiation. Masculinization at puberty results in masculine body build, axillary, facial and pubic hair, and deepening of the vioce. Breast development is minimal or absent. We have experienced recently a case of male hermaphroditism which was concerned to be a PPSH with the characteristics of external genitals, sex-chromatin pattern(sex-chromatin mass positive), chromosome study(karyotype 46XY) urinary steriod excretion (17-KS; normal value), laparoscopy(no Mullerian-duct structure), IVP (normal), and gonadal biopsy (atrophy of seminiferous tubule and decreased spermatogensis). Extragenital malformations were not detected and he was of normal intelligence. His sex was assigned male, and treatment consists of urethroplasty and resection of urogenital sinus.

小形航空機의 RCS와 GCS의 比較와 最大探知距離에 關한 硏究

陳年鋼,李亨龍,李璟埈 한국항공대학교 1972 論文集 Vol.4 No.-

本論文은 小形航空機의 後面에 關한 RCS의 값을 간단한 모델로 나누어 計算하는 理論的 計算方法과 內外部의 諸雜音의 영향에 관한 要因을 반영하고 쉽게 計算할 수 있는 量으로 나타낸 實用的 Radar最大探知距離計算式을 명료하게 定義했으며 普通 直接測定으로는 구하기 힘드는 數値를 쉽게 求할수 있는 圖表와 方程式을 소개했다. RCS(Radar Cross Section)값과 GCS(Geometrical Cross Section)를 比較했고 Radar로 탐색한 結果는 Radar의 理論値와 거의 一致함을 알았다. This paper presents a theoretical method to calculate the RCS value of the rear view on the drawing of aircraft in small size, which is devided into several simple models and the useful radar maximum range equation which reflects factors of the effects of both external and internal noise sources and atmospheric-absonption losses. The range equation is presented in terms of explicitly defined and readily evaluated quantities. Curves and equations are given for evaluating the quantities that are not ordinarily known by direct measurement. RCS (Rader Cross Section) is compared with GCS (Geometrical Cross Section) and the measured data are found to be nearly corresponding to the theoretical value.

누세관 손상에 대한 임상적 고찰

이영호,신극선,유재덕,진한식 大韓成形外科學會 1979 Archives of Plastic Surgery Vol.6 No.2

Injuries to the lacrimal canaliculi occur most frequently caused by glass fragments laceration in automobile accidents, fighting, sports injury and fragments impelled by high explosives. When injuries involving the lacrimal canaliculi are not perfectly repaired, faulty healing causes the traumatic epiphora. We had 25 cases of lacrimal canaliculi injuries who were admitted to plastic surgery of Severance hospital during the last 10 years. (from January, 1969 to December, 1978) These patients were clinically analyzed and got following results. 1. The incidence of lacrimal canaliculi injury was 25 cases(14.2%) of the total 176 eye trauma cases. 2. Male was predominated over female by the ratio 7.3:1. 3. The mean age was 27 years old. 4. Left side was predominated over right by the ratio 1.4:1. 5. The most frequent cause was fighting(32%), and car accident(20%) in next. 6. The most frequent site of associated injury was medial canthal ligament(36%), and eye ball(24%) in next. 7. The average time interval from injury to repair was 10 hours. 8. The material of internal splint was nylon(50%), polyethylene tube(20.8%), silastic rod(12.5%), musclene(12.5%), silk(4.2%). 9. The 4 cases of obstruction were seen postoperatively.

가토의 연골피막 이식시 접촉억제가 연골신생에 미치는 영향

이영호,나동균,유재덕,진한식 大韓成形外科學會 1982 Archives of Plastic Surgery Vol.9 No.1

Since 1972 a series of experiments (Skoog, Ohlsen & Sohn, 1972; Ohlsen, 1976) has been performed to elucidate the potential of perichondrial grafts to generate cartilage. In 1974 Sohn and Ohlsen demonstrated in rabbits that tracheal cartilage could be reconstructed from free perichondrial grafts. Clinically this potential was used in the treatment of the cauliflower ear and to correct protruding ears by perichondroplasty (Skoog, 1974), to reconstruct the small joints eyelid and septum (Brent and Ott, 1978). Recently perichondrial microvascular transfer was studied by Donski and O`Brien(1980). They summarized that there was no any distinct difference in cartilage formation in the vascularised and non-vascularised grafts. And that chondrogenesis was resulted from loss of “contact inhibition”and over production of cartilage was also resulted from loss of “contact inhibition”. In the study, various contacts of active surface of the perichondrial grafts were made and autografted from ear to dorsal region of the rabbits, and the following results were obtained. 1. The chondrogenesis of perichondrial grafts with induced “contact inhibition”was nearly abscent and new cartilage, if any formed, was very thin. 2. The “contact inhibition”was thought to be a important factor on chondrogenesis in perichondrial grafts. 3. The atraumatic technique was needed to substautially obtain the new cartilage from perichondrial grafts.