Ito 저색소증

이근수,장홍준,서연림,안규중,김종민,이종주 ( Geun Soo Lee,Hong Zoon Jang,Yeon Lim Suh,Kyu Joong Ahn,Jong Min Kim,Chong Ju Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

A Case of Hypomelanosis of lto Geun Soo Lee, M.D., Hong Zoon Jang, M.D., Yeon Lim Suh*, M.D., Kyu Joong Ahn, M.Dl., Jong Min Kim, M.D., Chong Ju Lee, M.D. Departments of Dermatology and Pathology*, Clooege of Medicine, Hallym University Seoul, Korea We report a case of hypomelansis of Ito developed in a 6-year-old male patient. He had numberous bizarre, hypopigmented streaky macules on the left side of the chest, and upper arm. The histopathologi findings demonstrated that hypopigmented areas contained slightly decreased basal pigmentation with decreased content of intracellualr melanin in keratinocytes and melanocytes and revealed neither inflammatory changes nor dropping of melanin granule into the dermis. The electron microscopic finding showed decreased number of melanosomes, incomplete melaniztion, and cytoplasmic vacuoles in keratinocytes and melanocytes. Extra-cutaneous alterations were not found.

퇴행성 요추 질환에서 후방 기기술 후 요추 시상 정렬의 변화

이종서,정성수,이종윤 대한정형외과학회 골.연부조직이식학회 2003 대한골.연부 조직이식학회지 Vol.3 No.1

Skyradiometer를 이용한 공주지역의 에어러솔의 광학적 특성

곽종흠,서명석,이태희,곽서연 公州大學校 基礎科學硏究所 2004 自然科學硏究 Vol.11 No.-

본 연구에서는 공주대학교 자연대 옥상에 설치된 분광복사측정기의 일종인 Skyradiometer로 측정된 직달 및 산란 일사량을 이용하여 간접적으로 공주지역의 에어러솔의 광학적 특성을 분석하였다. 분석기간은 2004년 1월부터 11월까지이며 에어러솔의 광학적 특성의 분석에 활용된 알고리즘은 Nakajima et al.(1996)이 개발한 Skyrad.pack.3이다. 주요 분석요소는 에어러솔의 광학두께(AOT), 단일 산란비율(SSA), 옹그스토롬 지수(α) 및 에어러솔의 크기별 분포이며 분석결과의 질을 높이기 위하여 초기 관측 자료의 품질검사를 수행하였다. 공주지역의 11개월 평균 AOT, α 및 SSA는 각가 0.6, 1.1, 그리고 0.9이며 계절 및 기상현상에 따라 큰 시간변동을 보이고 있다. 크기별 입자분포에서는 미세입자와 조대입자에서 최대치가 나타나는 바이 모달 형태를 보이고 있으며 황사(Asian dust) 기간인 봄철에는 조대입자의 총 부피가 크게 증가하였다. 이러한 현상은 봄철동안에 AOT와 SSA가 각각 크게 증가하고 감소하는 점에서도 확인되고 있다. 또한 공주지역의 에어러솔은 풍향에 큰 영향을 받지 않는 것으로 나타나고 있다. We investigate the optical properties of aerosols over Gongju by indirect method using the ground measurement, Skyradiometer. The analysis period is from January to November, 2004. Skyrad.pack.3 is used to estimate the optical properties, such as the aerosol optical thickness(AOT), single scattering albedo(SSA), Angstrom exponent(α) and size distribution, of aerosols from the ground measured radiance data. And quality control process is applied to the raw data to improve the quality of analysis results. The 11-month average of AOT, α and SSA are 0.6, 1.1, and 0.9 respectively. The averaged volume spectra of aerosols show a bi-modal distribution, first peak at fine mode and second peak at coarse mode. Asian dust events clearly increase the AOT and coarse particle, however it decrease the SSA. The effect of wind direction on the optical properties of aerosols over Gonju is not manifest.

동물의 장에서 분리한 Enterococcus sp.의 특성 및 분말화

박종진,변정수,조윤경,홍승서,이현수 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4

의약품 및 동물약품으로 사용되고 있는 분말유산균을 개발하고자 동물의 장에서 산성 pH 및 담즙산에 대한 내성이 강하고 대장균 생육억제력이 좋은 Enterococcus faecium L20을 분리 동정하고 이를 이용하여 고농도의 생균이 함유된 분말 유산균을 제조하였다. 분리된 균주는 pH 3.0에서 90% 이상의 내성과 0.3% 담즙산이 함유된 배지에서 100%의 내성을 나타냈으며 MRS 배지에서 대장균과 혼합배양시 24시간 이내에 대장균을 사멸시켰다. 분리된 균주를 산업용배지에서 배양한 후 동결건조시켜 분말을 만들었을 때 생균수는 5.0×0^11/g 이상이었다. 이것은 18℃에 보관하였을 경우 11개월 동안 80%의 생존율을 나타내었다. In order to develop a lactic acid bacterial powder which can be used as a probiotic for human and animal, a lactic acid bacteria which has high resistance against low pH and ox-gall, and shows a good growth inhibition against low pH and ox-gall, and shows a good growth inhibition against E. coli, was isolated from an animal intestine and characterized. The isolated strain was identified as Enterococcus faecium. It had more than 90% of survival at low pH for 2 hours and almost 100% of survival in the presence of 0.3% ox-gall. When co-cultured with E. coli in MRS broth, all of the E. coli cells were killed within 24 hours. The final powdered product of the isolated strain was manufactured after a freeze drying process suing an industrial media, and then checked its stability. Its storage stability was 80% for 11 months at 18℃.

良好한 照明이 우리 生活에 미치는 影響

金正洙,李鍾夏,徐相壽 忠州大學校 1968 한국교통대학교 논문집 Vol.2 No.-

In this paper ; I examined the condition for proper illumination with the study of its influence on our daily life and our health, and of the ideal illumination of our houses, buildings and facfories, on the standpoint of human engineering and I made an attempt to study on these problems through the examination in the influence of proper illumination on our sight, with one thousand children of the fourth, the fifth, and the sixth grade of the primary school in the city of Chungju as an object of the study.

Al-Si合金의 閃光法에 의한 熱擴散係數測定에 關한 硏究

許甫寧,裵源泰,徐弘三,李寬洙,朴種一 慶尙大學校 1984 論文集 Vol.23 No.2

本 硏究를 通하여 얻은 結果는 다음과 같다. 1. Al-Si 合金에서 Si量이 增加할수록 熱擴散係數는 감소하나, 共晶組成(Al-12%Si) 部近에서는 亞共晶, 過共晶組成에 비하여 약간 增加하였다. 비열과 비중등의 조건이 一定하다면 熱擴散係數는 pure Al 이 8.47, 亞共晶(6%)組成이 3.24, 共晶組成(12%)이 3.99, 過共晶組成(18%Si)이 3.01(×10-5m2/sec)이다. 2. Cu, P, Na로 개량처리 하였을 때 共晶組成이내에서는 Cu의 경우에 열확산계수가 가장 적었으나, 과공정조성에서는 Cu의 경우가 가장 높았다. After pure Al, Al-6% Si(hypoeutectic composition), Al-12% Si(eutectic comp.) and Al-18% Si(hypereutectic comp.) among Al-Si alloys were treated refinement with addition of Cu(0.5%), P(0.5%) or Na(0.5%), their thermal diffusivities were measured by flash method. And then their microstructures and thermal diffusivities were investigated. The results obtained are as follows. 1. According as sillicon contents in Al-Si alloys increase, the thermal diffusivities decreases, but it increases slightly at eutectic composition(Al-12% Si alloy), if its density and heat capacity are constant, the thermal diffusivities are 8.47(pure Al), 3.24(6% Si), 3.99(12% Si) and 3.01(18% Si) (X10-5m/sec) respectively. 2. When the refinement treated with Cu, P, and Na, the effects of thermal diffusivities of alloys with Cu treated is the lowest under eutectic composition, but its effects is the best at hypereutectc composition.

Angiolymphoid hyperplasia with eosinophilia associated with arteriovenous malformation

Seong Min Kang,Woo Jin Lee,Myoung Shin Kim,Chong Hyun Won,Sung Eun Chang,Ho Seok Suh1,Mi Woo Lee,Jee Ho Choi,Kee Chan Moon 대한피부과학회 2009 대한피부과학회 학술발표대회집 Vol.61 No.1

십이지장 제2부에 전이된 자궁경부암 1예

이화영,손희정,이규택,김재준,백승운,이종균,이준혁,고광철,이풍렬,이종철,손정일,서연림,전성국 대한소화기내시경학회 1997 Clinical Endoscopy Vol.17 No.1

In Korea, careinoma of the cervix is the most common malignancy in women annually affecting 25 per every 100,000 female. The widespread use of the Papanicolaou smear has resulted in earlier detection of the tumor and a reduction in the number of patients with advanced disease, but the incidence of cervix. carcinoma is still the fifth most common malignancy in the world. Cervical carcinoma spreads to the small bowel primarily by direct extension from involved lymph nodes, most commonly from peraaortic or mesenteric nodes to the serosa of the bowel. But, the involvement of small bowel by cervical carcinoma is so rare, and shows a maximum incidence of small bowel involvement of less than 1.5%. We report a patient with squamous cell carcinoma of the cervix metastases to the second portion of the duodenum in whom the diagnosis was made by endoscopic biopsy of the lesion.

Survival-Related Factors of Spinal Metastasis with Hepatocellular Carcinoma in Current Surgical Treatment Modalities : A Single Institute Experience

Lee, Min Ho,Lee, Sun-Ho,Kim, Eun-Sang,Eoh, Whan,Chung, Sung-Soo,Lee, Chong-Suh The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.58 No.5

Objective : Recently, the survival of patients with hepatocellular carcinoma (HCC) has been prolonged with improvements in various diagnostic tools and medical treatment modalities. Consequently, spine metastases from HCC are being diagnosed more frequently. The accurate prediction of prognosis plays a critical role in determining a patient's treatment plan, including surgery for patients with spinal metastases of HCC. We investigated the clinical features, surgical outcomes, and prognostic factors of HCC presenting with spine metastases, in patients who underwent surgery. Methods : A retrospective review was conducted on 33 HCC patients who underwent 36 operations (three patients underwent surgical treatment twice) from February 2006 to December 2013. The median age of the patients was 56 years old (range, 28 to 71; male : female=30 : 3). Results : Overall survival was not correlated with age, sex, level of metastases, preoperative Child-Pugh classification, preoperative ambulatory function, preoperative radiotherapy, type of operation, administration of Sorafenib, or the Tokuhashi scoring system. Only the Tomita scoring system was shown to be an independent prognostic factor for overall survival. Comparing the Child-Pugh classification and ambulatory ability, there were no statistically differences between patients pre- and post-operatively. Conclusion : The Tomita scoring system represents a practicable and highly predictive prognostic tool. Even though surgical intervention may not restore ambulatory function, it should be considered to prevent deterioration of the patient's overall condition. Additionally, aggressive management may be needed if there is any ambulatory ability remaining.

Synthesis and cytotoxicity evaluation of substituted pyridazino[4,5-b] phenazine-5,12-diones and tri/tetra-azabenzofluorene-5,6-diones

Lee, Hyun-Jung,Kim, Jin-Sung,Suh, Myung-Eun,Park, Hyen Joo,Lee, Sang Kook,Rhee, Hee-Kyung,Kim, Hwa Jung,Seo, Eun-Kyung,Kim, Choonmi,Lee, Chong-Ock,Choo Park, Hea-Young 이화여자대학교 약학연구소 2008 藥學硏究論文集 Vol.- No.18

The substituted pyridazino[4,5-b]phenazine-5,12-diones and tri/tetra-azabenzo[a]fluorene-5,6-diones were synthesized from 6,7-dichloroph-thalazine-5,8-dione and 6,7-dichloroquinoline-5,8-dione, respectively. The cytotoxic activities of the prepared compounds were evaluated by an SRB (Sulforhodamine B) assay against the following human cancer cell lines: A549 (lung), SK-0V-3 (ovarian), SK-MEL-2 (melanoma), XF 498 (CNS), and HCT 15 (colon). Almost all synthesized pyridazino[4,5-b]phenazine-5,12-diones (7a-j) presented higher cytotoxicity than that of doxorubicin (IC_(50) = 0.097-0.225 μM) against the cancer cell lines, In particular, the cytotoxicity of compounds 7f (R₁=Et) and 7h (R₁, R₂ = Me) against all human cancer cell lines examined was about 10 times higher than that of doxorubicin. However, the cytotoxicities of several synthesized azabenzo[a]fluorene-5,6-diones (12a, 12c, 12d, 12e, and 12g) against the cancer cell lines in vitro were comparable to those of doxorubicin.