http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
노승무 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Total gastrectomized patients frequently suffer from agastric syndromes such as lack of appetite, reduced food intake, malnutrition, weight loss, abdominal pain and other various complications. It is a hot topic to restore the intestinal continuity after total gastrectomy for gastric malignancy and even benign gastric disease. There are many methods for reconstruction and they have been compared since total gastrectomy was developed. I have performed 22 jejunal interposition operations between esophagus and duodenum after total gastrectomy for gastric cancer. The digestive continuity was renewed by an interposition of isoperistaltic jejunal loop, retrocolic fashion. Comparing this jejunal interposition method with Roux-en-Y procedure, I confirmed this reconstruction method is relatively simple and very effective technique. The author can draw a conclusion that interposition of the jejunal loop is one of the optimum reconstruction procedures after total gastrectomy in terms of the quality of life of the patients.
Rat의 복강에 삽입한 Filorouracil-Polyglycolic acid제형의 Fluorouracil용출에 관한 연구
노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
A common form of relapse in adenocarcinoma of the stomach is intraperitioneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adenocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.
노승무(Seung-Moo Noh) 한국의학교육학회 2002 Korean journal of medical education Vol.14 No.1
The purposes of this study are to describe some of the basic and practical services available on the internet, and to evaluate the efficacy of a lecture using the internet together with a traditional classroom lecture. Growing demands for better education and increasing amount of knowledge have brought up the need to use new methods in learning. Information and communication technology has given new opportunities and challenges in the field of education. Especially, the internet is creating information and communication spaces that are removing the traditional boundaries of time and location. It offers new ways to learn and communicate in the field of medical education. Medicine is a very suitable area to use WWW-based teaching, because a great part of it is based on visually learned topics. The internet carries vast quantities of information in all different formats and modalities such as text, figures, video and audio. Teaching and learning are complex processes, and a wide variety of techniques and facilities are needed for each student and subject, which may vary at different times. The internet will not, and should not, replace traditional classroom lectures or tutorials, but it dose have the ability to add value to these traditional teaching techniques and to make the life of the student and teacher a little easier, more varied and possibly more interesting. Preliminary results show that this kind of lecture is useful in teaching medicine, especially in self-oriented learning, but cannot replace totally a clinical teacher s share in the learning process. Feedback from the users shows that this education is widely used and needed. The internet is likely to play more important roles in many aspects of medicine in the future.
위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구
노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.