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김재환,이윤석,황인겸,강봉균,조재영,윤유석,한호성,황진혁 대한의학회 2015 Journal of Korean medical science Vol.30 No.3
The role of carcinoembryonic antigen (CEA) in pancreatic cancer remains poorlyunderstood. Therefore, this study aimed to determine whether CEA is complementary tocarbohydrate antigen 19-9 (CA19-9) in prognosis prediction after pancreatic cancercurative resection. We retrospectively reviewed records of 144 stage II curatively resectedpancreatic cancer patients with preoperative and postoperative CEA and CA19-9 levels. Patients with normal preoperative CA19-9 were excluded. R0 resection margin, adjuvanttreatment, and absence of angiolymphatic invasion were associated with better overallsurvival. There was no significant difference in median survival according to preoperativeCEA levels. However, patients with normal postoperative CA19-9 (59.8 vs.16.2 months,P < 0.001) and CEA (29.4 vs. 9.3 months, P = 0.001) levels had longer overall survivalthan those with elevated levels. Among 76 patients with high postoperative CA19-9 levels,a better prognosis was observed in those with normal postoperative CEA levels than inthose with elevated levels (19.1 vs. 9.3 months, P = 0.004). Postoperative CEA and CA19-9 levels are valuable prognostic markers in resected pancreatic cancer. Normalpostoperative CEA levels indicate longer survival, even in patients with elevatedpostoperative CA19-9.
Idiopathic Isolated Perigastric Omental Panniculitis
박종설,김서화,윤병욱,오병수,윤동식,홍누리,황인겸,장재훈,김용성 대한상부위장관ㆍ헬리코박터학회 2015 Korean Journal of Helicobacter Upper Gastrointesti Vol.15 No.3
Mesenteric panniculitis (MP) is non-specific inflammation of the adipose tissue that primarily involves the small bowel mesentery. Omental involvement has been rarely reported but we report a case of 25 years old woman with isolated lesser omental panniculitis. This patient was diagnosed by CT findings and recovered completely with conservative treatment. Invasive diagnostic methods or surgical exploration has been used to diagnose MP. However, all six reported cases of omental panniculitis including the current case showed a benign course; therefore, awareness of the CT findings is essential for the best diagnosis and management of omental panniculitis.
말초신경병증 통증 치료를 위해 투여한 Duloxetine 유발 저나트륨혈증 2예
이지은 ( Ji Eun Lee ),김현욱 ( Hyun Wook Kim ),서봉수 ( Bong Soo Seo ),라지은 ( Ji Eun Ra ),황인겸 ( In Kyeom Hwang ),이지경 ( Ji Kyoung Lee ),목영미 ( Young Mi Mok ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6
Duloxetine is a balanced serotonin and norepinephrine reuptake inhibitor available for treating peripheral neuropathic pain. The occurrence of hyponatremia as an adverse event of duloxetine treatment, but it has not yet been reported in Korea. Here, we report two cases of hyponatremia induced by duloxetine for treatment of peripheral neuropathic pain. Our findings highlight the need for special attention when using duloxetine in elderly patients taking thiazide diuretics. (Korean J Med 2012;83:813-816)
내시경 유두부 풍선 확장술 후 과다 출혈로 인한 대사성 뇌병증
이준영 ( June Young Lee ),김지현 ( Jee Hyun Kim ),장승현 ( Seung Hyeon Jang ),강봉균 ( Bong Kyun Kang ),황인겸 ( In Kyeom Hwang ),이윤석 ( Yoon Suk Lee ),황진혁 ( Jin Hyeok Hwang ),김재환 ( Jai Hwan Kim ) 대한췌장담도학회 2014 대한췌담도학회지 Vol.19 No.2
Endoscopic retrograde cholangiopancreatography is widely used for diagnosis and treatment of pancreatobiliary diseases and associated with a spectrum of complications such as pancreatitis, hemorrhage, and so on. Endoscopic papillary balloon dilatation (EPBD) has an advantage over endoscopic sphincterotomy in complication of bleeding. We report here on a 68-year-old woman who developed metabolic encephalopathy due to massive bleeding after EPBD. Massive bleeding was controlled after selective embolization and metabolic encephalopathy was improved after conservative management. Metabolic encephalopathy due to massive bleeding after EPBD has not been reported. We report on this unusual case along with a review of the related literatures.