http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
장승현,김동준,김재용,이갑덕,Jang, Seung Hyeon,Kim, Dong Jun,Kim, Jae Yong,Lee, Gap Deok 대한화학회 1994 대한화학회지 Vol.38 No.3
Methyl기를 포함하는 새로운 5종의 crown ether를 합성하였다. 2,3,4,5: 9,10,11,12-Dibenzo-8,8-dimethyl-15,18,1-trioxacycloeicosane, 2,3,4,5: 9,10,11,12-dibenzo-8,8-dimethyl-15,18,21,1-tetraoxacyclotricosane, 2,3,4,5 : 9,10,11,12-dibenzo-8,8-dimethyl-15,18,21,24,1-pentaoxacyclohexacosane, 2,3,4,5 : 9,10,11,12 : 22,23,24,25 : 29,30,31,32-tetrabenzo-8,8,28,28-tetramethyl-15,18,21,35,38,1-hexaoxacyclotetracontane 그리고 2,3,4,5 : 9,10,11,12 : 25,26,27,28:32,33,34,35-tetrabenzo-8,8,31,31-tetramethyl-15,18,21,24,38,41,44,1-octaoxacyclohexatetracontane은 (M = Na, K)존재하에서 4,4'-isopropylidenediphenol과 di-, tri- 그리고 tetraethyleneglycol ditosylate의 반응에 의해 합성하였다. Diethyleneglycol ditosylate, triethyleneglycol ditosylate, tetraethyleneglycol ditosylate는 NaOH존재하에서 diethyleneglycol, triethyleneglycol 그리고 tetraethyleneglycol과 p-toluenesulfonylchloride의 반응에 의해 합성하였다. Five new crown ethers containing methyl groups were synthesized. 2,3,4,5: 9,10,11,12-Dibenzo-8,8-dimethyl-15,18,1-trioxacycloeicosane, 2,3,4,5: 9,10,11,12-dibenzo-8,8-dimethyl-15,18,21,1-tetraoxacyclotricosane, 2,3,4,5 : 9,10,11,12-dibenzo-8,8-dimethyl-15,18,21,24,1-pentaoxacyclohexacosane, 2,3,4,5 : 9,10,11,12 : 22,23,24,25 : 29,30,31,32-tetrabenzo-8,8,28,28-tetramethyl-15,18,21,35,38,1-hexaoxacyclotetracontane and 2,3,4,5 : 9,10,11,12 : 25,26,27,28:32,33,34,35-tetrabenzo-8,8,31,31-tetramethyl-15,18,21,24,38,41,44,1-octaoxacyclohexatetracontane were synthesized by reaction of 4,4'-isopropylidenediphenol with di-, tri-and tetraethyleneglycol ditosylate in the presence of MOH(M = Na, K). Di-, tri- and tetraethyleneglycol ditosylate were synthesized by reaction of p-toluenesulfonylchloride with diethyleneglycol, triethyleneglycol and tetraethyleneglycol in the presence of NaOH.
새로운 비스-크라운 에테르류의 합성 (제 1 보) : 실옥산 사슬에 연결된 크라운 에테르
장승현,김재용,Jang, Seung Hyeon,Kim, Jae Yong 대한화학회 1994 대한화학회지 Vol.38 No.5
실옥산 사슬과 크라운 에테르가 연결된 유연성이 큰 2가지 새로운 비스-크라운 에테르를 합성하였다. 1,3-Bis(trimethylsiloxy)-1,3-dimethyl-1,3-dipentaoxacyclohexadecamethyl disiloxane(1)는 백금촉매 존재하에서 3-methylene-16-crown-5 (8)과 1,3-bis(trimethylsiloxy)-1,3-dimethyl disiloxane (10)의 반응에 의해 합성하였다. 1,1,3,3,5,5-Hexamethyl-1,5-dipentaoxacyclohexadecamethyl trisiloxane (2)은 백금촉매 존재하에서 crown ether (8)과 1,1,3,3,5,5-hexamethyl trisiloxane (11)의 반응에 의해 합성하였다. 3-Methylene-13-crown-4 (7), 3-methylene-16-crown-5 (8), 및 3-methylene-19-crown-6 (9)은 NaH 존재하에서 triethylene glycol (3), tetraethylene glycol (4), 및 pentaethylene glycol (5)을 각각 3-chloro-2-chloro-methyl-1-propene (6)와 반응시켜서 합성하였다. New bis-crown ethers containing siloxane chain were synthesized. 1,3-Bis(trimethylsiloxy)-1,3-dimethyl-1,3-dipentaoxacyclohexadecamethyl disiloxane (1) was synthesized by reaction of 3-methylene-16-crown-5 (8) with 1,3-bis(trimethylsiloxy)-1,3-dimethyl disiloxane (10) in the presence of Pt catalyst. 1,1,3,3,5,5-Hexamethyl-1,5-dipentaoxacyclohexadecamethyl trisiloxane (2) was synthesized by the reaction of crown ether (8) with 1,1,3,3,5,5-hexamethyl trisiloxane (11) in the presence of Pt catalyst. 3-Methylene-13-crown-4 (7), 3-methylene-16-crown-5 (8), and 3-methylene-19-crown-6 (9) were synthesized by the reaction of triethylene glycol (3), tetraethylene glycol (4), and pentaethylene glycol (5) respectively with 3-chloro-2-chloro-methyl-1-propene (6) in the presence of NaH.
증례 : 소화기 ; 크론병 환자에서 발생한 간세포암 1예
장승현 ( Seung Hyeon Jang ),김지현 ( Jee Hyun Kim ),이재우 ( Jae Woo Lee ),이준영 ( June Young Lee ),조영윤 ( Young Youn Cho ),최원묵 ( Won Mook Choi ),정현채 ( Hyun Chae Jung ) 대한내과학회 2015 대한내과학회지 Vol.88 No.4
간세포암은 주로 간경화증이나 바이러스 간염 등의 만성간 질환을 가진 환자에서 발생하며 기저에 만성 간 질환이 없는 크론병 환자에서 간세포암이 발생하는 경우는 극히 드물다. 지금까지 보고된 몇몇 국외의 증례들을 살펴보면 비교적 젊은 나이에 크론병이 발생하여 크론병의 유병 기간이 길고 azathioprine을 포함한 면역억제제를 장기간 사용하였다. 만성 간 질환이 없던 34세 남자 크론병 환자가 14년간아자티오프린 치료 및 반복적인 수술을 받았다. 추적 관찰하던 중 결장 천공과 결장 주위 농양으로 입원하였고 당시 시행한 전산화 단층촬영에서 결장 천공과 간의 종양이 발견되었다. 간의 종양은 간 조직 검사에서 기저에 간경화증 등의 특별한 병리학적 소견 없이 간세포암이 확인되었다. 결장 주위 농양과 결장 천공에 대해 우측 결장 절제술을 시행하였고 간세포암에 대해 간동맥 화학색전술 및 고주파 열치료를 시행하였다. 본 증례는 국내에서는 처음 보고되는 증례로 이전 보고되었던 증례와는 달리 원발성 경화성담관염이나 국소적 간 글리코겐증 등의 병리학적 소견을 보이지 않았다. 저자들은 만성 간 질환이 없는 크론병 환자에서 간세포암이 발생한 드문 증례를 문헌고찰과 함께 보고하는 바이다. Hepatocellular carcinomas (HCCs) in patients with Crohn`s disease (CD) without underlying chronic hepatitis or liver cirrhosis are extremely rare. Previously reported cases occurred in patients who had developed CD at a young age and had been treated with immunosuppressive agents long-term. We herein report the first case of HCC in a 34-year-old patient with CD in Korea. The patient was treated with azathioprine for 14 years and had undergone repeated surgeries for CD. During the follow-up period, the patient was hospitalized for colon perforation and pericolic abscess formation. Computed tomography showed a liver mass, and HCC was diagnosed based on liver biopsy. The patient underwent right hemicolectomy for colon perforation and transcatheter arterial chemoembolization followed by radiofrequency ablation for the HCC. The present case is similar to previously reported cases with the exception of the liver pathology findings, which exhibited neither primary sclerosing cholangitis nor focal hepatic glycogenolysis.
서정기,김인환,장승현,김병옥,류재욱,박정학,Seo, Jeong Gi,Kim, In Hwan,Jang, Seung Hyeon,Kim, Byeong Ok,Ryu, Jae Uk,Park, Jeong Hak Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.4
Poly(p-tert-butyltrimethoxymonopropyloxycalix[4]arene-methylsiloxane) (TBCX-MS) has been prepared and used as a stationary phase in isothermal capillary gas chromatographic separation of some positional isomers. Retention factors (k) and separatio n factors $(\alpha)$ for the isomers were measured and compared with those on poly(p-tert-butyl-dimethoxydipropyloxycalix[4]arene-tetramethyldisiloxane) (TBCX-TMDS), poly(dimethoxydipropyloxycalix[4]arenetetramethyl-disiloxane) (CX-TMDS). Most of the isomers investigated are well resolved on TBCX-MS. Retention of all the compounds decreases on the three phases in the order, TBCX-TMDS ${\geq}$ TBCX-MS > CX-TMDS. Similar retention values on TBCX-TMDS and TBCX-MS seem to indicate that retention property of the two phases is not significantly affected by the spatial position of the calixarene moiety.
내시경 유두부 풍선 확장술 후 과다 출혈로 인한 대사성 뇌병증
이준영 ( June Young Lee ),김지현 ( Jee Hyun Kim ),장승현 ( Seung Hyeon Jang ),강봉균 ( Bong Kyun Kang ),황인겸 ( In Kyeom Hwang ),이윤석 ( Yoon Suk Lee ),황진혁 ( Jin Hyeok Hwang ),김재환 ( Jai Hwan Kim ) 대한췌장담도학회 2014 대한췌담도학회지 Vol.19 No.2
Endoscopic retrograde cholangiopancreatography is widely used for diagnosis and treatment of pancreatobiliary diseases and associated with a spectrum of complications such as pancreatitis, hemorrhage, and so on. Endoscopic papillary balloon dilatation (EPBD) has an advantage over endoscopic sphincterotomy in complication of bleeding. We report here on a 68-year-old woman who developed metabolic encephalopathy due to massive bleeding after EPBD. Massive bleeding was controlled after selective embolization and metabolic encephalopathy was improved after conservative management. Metabolic encephalopathy due to massive bleeding after EPBD has not been reported. We report on this unusual case along with a review of the related literatures.
췌장 낭성 종양으로 오인된 췌장 내 부비장의 유표피 낭종 2예
김지현 ( Jee Hyun Kim ),정광현 ( Kwang Hyun Chung ),오수연 ( Soo Yeon Oh ),이준영 ( June Young Lee ),장승현 ( Seung Hyeon Jang ),이상협 ( Sang Hyub Lee ),류지곤 ( Ji Kon Ryu ),김용태 ( Yong Tae Kim ) 대한췌장담도학회 2014 대한췌담도학회지 Vol.19 No.1
Epidermoid cyst in the intrapancreatic accessory spleen is extremely rare condition which could be mistaken for pancreatic cystic neoplasm. We report two cases of epidermoid cysts of intrapancreatic accessory spleen which mimicking pancreatic cystic neoplasm. Two patients, both male, aged 47 and 53 respectively were referred to our department for pancreatic mass. One was asymptomatic, whereas the other presented worsening abdominal pain and progressive weight loss. In both cases, the mass with cystic component was detected in the pancreatic tail in a computed tomography scan. Under a suspicion of pancreatic cystic neuronendocrine tumor, they underwent a distal pancreatectomy. Pathologic feature of resected specimens were shown to benign squamous lined cyst with splenic tissue in and around cyst wall which suggested that epidermoid cysts in the accessory spleen. We should take into account the possibility of epidermoid cyst in the intrapancreatic accessory spleen in the differential diagnosis of pancreatic cystic lesion. Korean J Pancreatobiliary 2014;19(1):52-58