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Objectives: This review aims to report the efficacy of Oriental herbal medicine for Female Idiopathic Precocious Puberty Methods: We searched clinical study about precocious puberty from Pubmed, OASIS, Korea Traditional Knowledge Portal and National Assembly Library up to July 2017. Results: Four case reports have been identified. Six cases in total were found. And in the four cases where estradiol (E2) levels were above the normal levels in pre-treatment, the figures dropped to the normal levels in post-treatment. In the three cases with breast development and breast pain in pre-treatment, symptoms improved after the treatment. And, the sustained growth of height was reported in the four cases with the treatment duration of 30 days or more. Conclusions: It has been identified that oriental medicine assisted improvements of hormone levels and breast pain and growth of height on patients with precocious puberty, yet more case reports and well-designed studies would be necessary to guide better oriental herbal medicine treatment of precocious puberty.
This study was conducted to evaluate the inhibitory effect of polygoni cuspidati radix (PCR) extract on osteoclast differentiation. Methods: MTT-assay was performed to estimate cytotoxicity of PCR extractin BMMs stimulated with RANKL. Tartrate resistant acid phosphatase (TRAP)staining, TRAP activity and RT-PCR were performed to know the inhibitory effecton osteoclast differentiation. actin ring formation were analysed to observe the effect of PCR extract. Results: PCR decreased the number of TRAP positive cells and TRAP activitiesin BMMs stimulated with RANKL and M-CSF. PCR restrained the formation ofactin ring. PCR down regulated the induction of NFATc1, c-Fos, TRAP and OSCARby RANKL. PCR inhibited NF-κB activity by inducing degradation of IκBα. Conclusions: We suggest that PCR Extracts can be an effective therapeutic agenton osteoclast differentiation caused by diseases such as osteoporosis.
본 논문은 남북한 관광자원개발 계획특성에 대한 우선순위를 비교분석하는데 연구의 목적이 있다. 실증분석 을 위한 자료수집은 남한과 북한 및 중국의 관광자원개발 전문가를 대상으로 하였다. 유효표본은 252부이었고, 남한 에서 회수된 설문지는 154부, 중국에서 회수된 설문지는 98부였다. 조사기간은 2012년 5월 15일로부터 12월 5일까지 실시하였다. 분석결과를 보면 관광자원개발 계획영역별 우선순위 분석결과에서 남한은 개발내용이 우선순위 1위였고, 북한은 개발주체가 우선순위 1위로 평가되었다. 관광자원개발 평가대상별 우선순위 분석결과 개발내용 평가대상 가운 데서 남한은 문화관광대상개발 북한은 자연관광대상개발, 개발목표 평가대상 가운데서는 남북한이 관광경제성, 개발 형태 평가대상 가운데서 남한은 특수목적관광자원개발 북한은 관광특구(단지)개발, 그리고 개발주체 평가대상 가운데 서는 남북한 모두 제3섹터형이 우선순위 1위로 평가되었다. The purpose of this study is to identify the priorities with respect to the characteristics of tourism resources development plan between the South and the North Korea. Through a preliminary investigation 287 lists of questions were distributed from May 14, 2012 to December 5, 2012 and from among them 252 lists were used. Expert Choice 11.5 was used to do pairwise comparisons and priorities assessment. Based upon the results of empirical analysis, the priority order sets of the domain of tourism resources development plan should be related to the development contents, the development objects, the development patterns, and the development subjects in the South Korea. Those should be related to the development subjects, the development objects, the development contents, and the development patterns in the North Korea.
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현재, 전 국토의 도시화 현상 및 지방자치시대가 본격화 되면서 주민들은 토지권리에 대한 재한사항에 많은 관심을 기울이게 되었고, 이로 인해 민원ㆍ행정업무의 주민 요구사항이 복잡하고 다양한 형태로 전개됨에 따라 이를 해결하기 위한 통합 토지이용관리 시스템이 필요성이 제기되고 있다. 본 논문은 토지 이용에 관련된 민원업무 및 행정업무를 통합전산화 함으로써 토지 이용에 관련된 전반적인 사항을 분석, 수정하고, 이에 관련된 각종 문서를 발급하기 위한 토지이용관리 시스템을 개발하기 위한 것이다. 본 연구를 통하여 개발된 시스템은 데이터베이스 서버, 데이터 입력 PC, 대장 발급 PC와 DBMS 서버로 총 4개의 컴포넌트로 구성되어 있다. 데이터베이스 서버는 운영체제를 Windows 2000 server를 사용하였고, DBMS(Database Management System)으로는 SQL Server를 사용하였다. 데이터 입력 PC는 데이터베이스 서버에 자료를 전송하기 전에 대장 발급 PC에 호완이 가능하도록 데이터를 수정, 편집, 그리고 변환하는 PC를 말하며, 대장 발급 PC는 데이터베이스 서버에서 자료를 받아 토지 이용 관리 애플리케이션을 통해 발급하는 기능을 가진 PC를 말한다. 데이터베이스 서버의 데이터 입력 PC는 상용 프로그램을 가지고 구축하였으며, 대장 발급 PC의 애플리케이션인 토지 이용 관리 시스템은 GDK를 기반으로 개발하였다. 본 연구를 통하여 개발된 토지 이용 관리 시스템으로 토지 이용 관리 업무를 효율적으로 처리할 수 있었고, 여러 기관에서 발급된 주제도를 통합 관리함으로써 관리자 및 민원인의 불편을 최소화 할 수 있을 것으로 사료된다. Currently, the urbanization of the entire national land and the establishment of local/regional self-governing systems have been being regularized in full scale. Accordingly, land and/or property owners throughout the nation have become keenly interested in the overall issues surrounding their rights as land and/or property owners. As their demands for their rights and the areas of issues involved become more complex and varied, the government offices handling these issues have been trying to standarize and regulate civil and administrative policies in place, Which can cover all the variety of these demands and needs involving land and property ownership. Also, due to the rapid urbanization, we observe an ever increasing needs for mapping of land use for multiple purposes. The purpose of this study is to develop a land use management system. The system developed for this system consists of four components a server operation system, a database management system servel, a data inputting personal computer, and an official document offering computer. The Windows 2000 server was used for the data base server operation system and SQL server was used for the database management system. The data inputting personal computer cleans, edits and transforms the data prior to transmitting it to the official document offering computer in order to facilitate the communication of the data between the two computers. The official document effering computer is a PC which applies the land use management system to the data it receives from the database server and generates official documents. The database server and the data inputting personal computer were built using the commercially available pregrams and the application software at the official document offering computer, "land use management system", was developed on the bassis of GDK. The result of this study proves that the land use management system developed for this study can enhance the efficiency of managing issues involving land use. It also indicates that we can alleviate the complaints raised by the administrative staff and by the public discontentors if we manage land use by integrating the thematic maps issued by the various administative branches.
박남춘,강나훈,유은실,이진욱,윤준걸,이진무,이창훈,장준복,황덕상,Park, Nam-Chun,Kang, Na-Hoon,Yoo, Eun-Sil,Lee, Jin-Wook,Yoon, Jun-Geol,Lee, Jin-Moo,Lee, Chang-Hoon,Jang, Jun-Bok,Hwang, Deok-Sang 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.18 No.4
Objectives: This review aims to report the efficacy and safety of electroacupuncture in the treatment of primary dysmenorrhea. Methods: We searched for randomized controlled studies (RCTs) using electroacupuncture on primary dysmenorrhea up to Dec 2016. The following databases were searched : OASIS, PubMED, EMBASE, CENTRAL. The results of the studies were analyzed and the risk of bias was assessed. Results: Five studies were included in this review. In most studies, the effect of electroacupuncture at Sameumgyo (SP6) was better than that of electroacupuncture at Hyeonjong (GB39), nonacupoint and no intervention about Visual analog scale (VAS), Verbal rating scale (VRS) and Retrospective symptom scale (RSS). But there were no significant effects on Resistance Index (RI) and S/D ratio (the ratio between peak systolic to end-diastolic flow velocity in uterine arteries). Serous adverse events were not reported. Conclusions: This review shows that electroacupuncture is effective on primary dysmenorrhea with no serious adverse events.
이해솔,한인식,선승호,김근엽,고호연,김태훈,이진무,장준복,송윤경,고성규,최유경,정종진,고유미,정금란,전찬용,Lee, Hye-Sol,Han, In-Sik,Sun, Seung-Ho,Kim, Geun-yeob,Go, Ho-Yeon,Kim, Tae-Hoon,Lee, Jin-Moo,Jang, Jun-Bok,Song, Yun-Kyung,Ko, Seong-Gyu,Cho 대한예방한의학회 2017 대한예방한의학회지 Vol.21 No.1
Objectives : This study's aim is to investigate clinical studies of cold hypersensitivity of hands and feet (CHHF) published in Korea and to explore the direct of future research. Methods : We searched clinical studies of CHHF using the database, such as DBpia(http://www.dbpia.co.kr/), NDSL(www.ndsl.kr), OASIS(http://oasis.kiom.re.kr), and RISS(www.riss.kr). The search words were 'cold hypersensitivity(冷症)' and 'syncope(厥證)'. Inclusion criteria were randomized controlled trials (RCTs), non RCTs, Before and after clinical study (B&A) about CHHF. Selection journals and data extraction were conducted by HS Lee and SH Sun independently. Results : Total twenty-one articles were selected finally. RCTs, non-RCTs, and B&A were 3, 12, and 6, respectively. The topics for CHHF were classified into three categories: effect of treatment (n=2) characteristics (n=11), and diagnosis (n=8). Conclusions : This results showed that RCT about CHHF and treatment effect of cold hypersensitivity of hands and feet were small in number. Further systemic and larger studies about CHHF will be needed.
선승호,고호연,고승우,조윤영,신지혜,김태훈,최동준,이진무,장준복,정기용,송윤경,고성규,최유경,임은미,박종형,전찬용,Sun, Seung-Ho,Go, Ho-Yeon,Ko, Seungwoo,Cho, Yoon-Young,Shin, Ji-Hye,Kim, Tae-Hoon,Choi, Dong-Jun,Lee, Jin-Moo,Jang, Jun-Bok,Jung, Ki-Yon 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.3
Objective : The purpose of this study is to figure out the treatment of coldness in hands and Feet by using Delphi survey. Method : This study was approved by institutional review boards at Kyung Hee University. Self recording type delphi survey were sent by e-mail to 55 Korean medicine specialists (19 gynecologist, 36 internal medical doctors) who treat coldness in hands and Feet. And replies were analyzed. As this study is cross sectional study, simple descriptive analysis was applied. Results & Conclusion : Herbal medicine, acupuncture and moxibustion were mainly applied and extract (granule), pharmacopuncture, bee venom pharmacopuncture and cupping therapy were also added case by case. Treatment was done twice a weak for 4 months. Cupping therapy was done at GB21 and SI11. Bee venom pharmacopuncture and Kidney yang deficiency pharmacopuncture were applied at ST36, GB21, CV4 and LR3. As extract (granule) Ijungtang, Dangguisayeokgaosuyusaenggangtang and Dangguisayeoktang were mainly used and as herbal medicine formula Palmijihwangwon, Bojungikgitang, Ijungtang, Danggwisayeok-gaosuyusaenggangtang and Danggwisayeoktang were mainly prescribed. Comprehensive treatment of acupuncture, moxibustion and herbal medicine was considered to have more effective and more rapid result than single treatment of herbal medicine have.
이진욱,강나훈,유은실,박남춘,양혜린,김남훈,박경선,이진무,이창훈,장준복,황덕상,Lee, Jin-Wook,Kang, Na-Hoon,Yoo, Eun-Sil,Park, Nam-Chun,Yang, He-Rynn,Kim, Nam-Hoon,Park, Kyoung-Sun,Lee, Jin-Moo,Lee, Chang-Hoon,Jang, Jun-Bok,Hwang, Deok- 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4
Objectives: Bee Venom has been used to relieve pain and to treat various diseases, such as arthritis, cancer and skin disease. Although Bee Venom has used extensively in gynecological fields, we don't have enough evidence with it. This study is to investigate efficacy and safety of Bee Venom on women by investigating papers, then we are going to suggest the direction of research. Methods: We searched for papers which had Bee Venom from Pubmed, OASIS, Journal of Korean Obstetrics & Gynecology, Journal of Korean Medicine up to August 2017, then classified according to the type of studies. Results: Eleven papers have been finally selected. One paper was a case report about atypical squamous cells of undetermined significance. Four papers were in vivo studies about 1 endometriosis and 1 polycystic ovarian syndrome and 2 human cervical cancer. Among eight papers that were in vitro studies, four papers were reported about ovarian cancer and four papers reported about human cervical cancer. Among ten papers that were experimental studies, two papers have been studied both in vivo and in vitro. Most of studies have shown that Bee Venom is useful for gynecological disorders. Conclusions: It has been identified that Bee Venom could be a good treatment for female disorder. However, more clinical reports and well-designed studies will be needed.