소(牛)의 제1위 평활근 운동성에 대한 histamine의 효과

윤병철,한호재,한방근,Yoon, Byeong-cheol,Han, Ho-jae,Han, Bang-keun 대한수의학회 1994 大韓獸醫學會誌 Vol.34 No.3

Effects of histamine on the ruminal smooth muscle motility of cattle were investigated in the longitudinal and circular smooth muscle strips. In order to these experiments, specimens were obtained from 35 korean native cattles, 3-4 years old, in Kwang-ju area slaughterhouse. Smooth muscle strips of rumen were made from sample, and then measured the isometric contraction with physiograph in $37{^{\circ}C}$ organ bath. The results were as follows : 1. Histamine caused two different types of response(a contraction or a relaxation) on the smooth muscle of cattle rumen. These responses increased in dose dependant manner. 2. Pyrilamine($H_1$-receptor antagonist) completely blocked contraction in all the preparation and converted the response into relaxation. 3. Cimetidine($H_2$-receptor antagonist) completely blocked relaxation in all the preparation and converted the response into contraction. 4. The contraction induced by histamine($10^{-3}M$) was not Mocked by cholinergic, adrenergic blocker or hexamethonium. 5. The contraction induced by histamine($10^{-3}M$) was markedly inhibited in the $Ca^{2+}$ free(or EDTA 2Na) Kreb's solution and by verapamil.

고선형 HBT 전력증폭기 설계를 위한 비선형 G<SUB>m</SUB> 및 sweet spot 추출

윤병철(Byeong-Cheol Yoon),황성운(Sung-woon Hwang),김정현(Jung-Hyun Kim) 대한전자공학회 2022 대한전자공학회 학술대회 Vol.2022 No.6

5G 어플리케이션을 위한 광대역 저잡음 증폭기에 관한 연구

윤병철(Byeong-Cheol Yoon),김정현(Jung-Hyun Kim) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.2

본 논문은 광대역 특성이 향상된 저잡음 증폭기를 제안한다. 광대역 특성을 실현하기 위해 피드백 저항과 버퍼를 이용하였으며, CMOS 공정을 기반으로 구현하였다. 5G sub-6Hz 주파수 밴드인 3GHz~6GHz 으로 목표 주파수를 설정 하였으며 시뮬레이션 결과 해당 대역에서 최소 잡음지수 1.8dB, 최고 증폭도 23dBm, Input P_1dB -32dBm 의 특성을 가진다.

연구논문 : 한국 전문대학과 미국 지역사회대학의 직업교육에 관한 비교 연구

안현순 ( Hyun Soon Ahn ),고정민 ( Jung Min Koh ),윤병철 ( Byeong Cheol Yoon ) 한국미용학회 2007 한국미용학회지 Vol.13 No.3

This study focuses on drawing success factors of Korean traditional folk play, The purpose of this essay is to study of the vocational education between Korean Junior Colleges and American Community Colleges in the viewpoint of comparative education and to explore its educational implications for the education of Korean Junior Colleges. And also this study explores the alternative how Korean Junior Colleges will be the center of vocational education. We examine the developmental process, the purpose of vocational education, educational feature of Korean Junior Colleges. Especially, we examine the developmental process Dept. of Skin & Beauty of Korean Junior Colleges in social and economic point. And then we explore the developmental process of American Community Colleges in the viewpoint of comparative education. American Community Colleges have a lot of good ideas and policies. They have some implications for the education of Korean Junior Colleges: First, They develope various incoming students sources. Second, They make a place as life-long education institutes. Third, They closely communicate with community through different educational programs.

Mesangial 세포에서 고포도당에 의해 유도되는 insulin-like growth factor 분비 촉진작용에 대한 ginsenosides의 차단 효과

배춘식(Chun-Sik Bae),임도선(Do-Seon Lim),윤병철(Byeong-Cheol Yoon),정문진(Moon-Jin Jeong),윤경철(Kyung-Chul Yoon),박수현(Soo-Hyun Park) 한국생명과학회 2008 생명과학회지 Vol.18 No.1

인삼은 고전적으로 항당뇨 효과가 있는 것으로 보고되고 있다. Insulin-like growth factor (IGF) 역시 당뇨병성 신증의 발병 초기에 중요한 역할을 하는 것으로 알려져 있다. 이에 본 연구에서는 mesangial 세포에서 고포도당에 의한 IGF 분비에 대한 ginsenoside의 차단 효과 및 이와 관련된 신호전달계를 알아보았다. 결과는 다음과 같다. 고포도당에 의해 증가 되었던 IGF-Ⅰ 및 IGF-Ⅱ 분비 촉진 작용은 GTS, PD 및 PT 처리 시 차단되었으며, 세포 성장 촉진작용에서도 같은 효과를 볼 수 있었다. 아울러 고포도당에 의한 산화성 스트레스 증가, GSH 감소, AA 방출 증가 작용 및 PGE2 합성 증가 작용은 GTS 처리시 현저하게 차단되었으며 PD 및 PT 처리 시 역시 억제 되는 것으로 나타났다. 이상의 결과를 볼 때 mesangial 세포에서 ginsenoside는 산화성 스트레스 및 arachidonic acid 활성 경로를 억제하여 고포도당에 의한 IGFs 분비 작용을 차단하는 것으로 나타났다. Panax ginseng C. A. MEYER is one of the most widely used herbal medicines in the Asian countries and has diverse functions including anti-diabetic action. The dysfunctions of mesangial cells in hyperglycemic conditions are implicated in the development of diabetic nephropathy. Insulin-like growth factors (IGFs) are also associated with the onset of diabetic nephropathy. Thus, we examined the effect of ginsenosides against high glucose-induced dysfunction of primary cultured rat mesangial cells. In the present study, high glucose increased IGF-I and IGF-II secretion in mesangial cells. Ginsenoside total saponin (GTS) prevented high glucose-induced increase of IGF-I and IGF-II secretion in mesangial cells. In addition, GTS prevented high glucose-induced increase of lipid peroxide formation and decrease of GSH contents. GTS also ameliorates high glucose-induced increase of arachidonic acid release and decrease of prostaglandin E2. In conclusion, GTS prevented high glucose-induced dysfunction of mesangial cells via inhibition of oxidative stress and arachidonic acid pathways.

소고기의 유통 단계별 병원성 미생물 오염도에 관한 연구

박성도 ( Seong Do Park ),김용환 ( Yong Hwan Kim ),고바라다 ( Ba Ra Da Koh ),김철희 ( Cheol Hee Kim ),윤병철 ( Byeong Cheol Yoon ),김조균 ( Cho Kyun Kim ) 한국가축위생학회 2002 韓國家畜衛生學會誌 Vol.25 No.2

Contamination levels of pathogenic microorganisms in 145 cases of beef, which were distributed in Gwangju province, had been investigated in each distributed stage and also monitored by general bacterial count and E coli count index. General bacterial count of beef from the slaughterhouse was 10(4) cfu/g less than the level of promotion(10(5) cfu/cm2) and E coli count index was also under the level of 10(2) cfu/cm2 recommended level of the ministry of agriculture and forestry. Pathogenic microorganisms were detected from 23.2% of samples in the consumption stage, 12.5% in the slaughtering stage and 5.6% in the transporting and processing stage. Staphylococcus aureus was isolated in the largest number and its ratio was 9.0%, listeria monocytogenes 5.5% and salmonella spp 1.4%. There were no samples that bacteria had been detected dually. E coli O157:H7 and campylobacter jejuni were not isolated. In raw and chilled beef, isolation rate of pathogenic microorganisms were 13.3% and 16.5% each. Especially in raw beef, L monocytogenes was isolated in 3 samples among 30 cases (10%) and S aureus in one sample (3.3%). According to a scale of meat store, isolation rates of pathogenic microorganisms were different. It was 28.6% in the small-scale meat store and 16.7% in the large-scale meat store each. Four cases (16.7%) of S aureus were isolated in the large-scale meat store and seven cases (20.0%) of Lmonocytogenes and 2 cases (5.7%) of salmonella spp were isolated in the small-scale meat store. S aureus was isolated in two places among 10 feeding facilities of the elementary school. This result shows that the sanitation of elementary school feeding facilities is so poor and more careful policy consideration is needed. Eleven strains of S aureus isolated showed β-hemolysis on blood agar, 1 strain α-hemolysis, and 1 strain γ-hemolysis. Isolated strains of L monocytogenes were reconfirmed in 560 bp. by PCR. Conclusively, these results show that the sanitary condition in the stages of slaughtering, transportation-processing and consumption influences the degree of pathogenic microorganisms contamination in beef severely. It is necessary to apply thoroughly hazard analysis critical control point in a process of beef distribution and also to develop rapid test methods for microorganism diagnosis. This effort is very important for the supply of safe and clean meat from farm to table and helpful for the improvement of public health.

안검 황색종 환자의 임상적 관찰과 혈액 지질 농도

안현순,윤병철 광주보건대학 2001 論文集 Vol.26 No.-

Background: It has been debated that serum lipid levels of patient with xanthelasma are higher than those of normal persons. In Korean literature, there are not any reports of this. Objective: Our purpose was to review the finding sin patient with xanthelasma and compare the patients to normal persons in respect of serum lipid levels. Methods: Fifty-one patients with xanthelasma were reviewed. Results: Mean age was 51 years in man and 51 years in woman. The ratio of male to female patients was 1:2.7. Significant difference of serum HDL-cholesterol leve was found between patients with normal liped level and normolipidemic control subjects. Conclusion: Xanthelasma palpebrarum occurs frequently in middle-aged women and HDL-cholesterol level of patients with xanthelasma was lower than normolipidemic control subjects.

복수를 동반한 호산구성 소장염 1예

박경남,이민호,최호순,이동후,손주현,기춘석,함준수,전용철,이웅수,손영우,윤병철,윤경택 대한소화기학회 2000 대한소화기학회지 Vol.35 No.4

Eosinophilic gastroenteritis is a rare disease of unknown cause and presents with tissue eosinophilia, which can involve different layers of gut wall and show different gastrointestinal symptoms according to the invaded lesion or layer without parasitic infestation. A pathologic and clinical classification of eosinophilic gastroenteritis is based on the predominent layer of the gut wall involved. Serosal involvement is observed in the rarest form that is associated with eosinophilic ascites and dramatic steroid response. A 15-year-old woman with lower abdominal pain visited our hospital. She had a peripheral blood eosinophilia and moderate amount of ascites that is mainly composed of eosinophils. Small bowel series showed diffuse mucosal thickening from the duodenum to the ileum. We diagnosed the case as eosinophilic enteritis with ascites on the basis of clinical, laboratory, radiologic findings. She was treated with corticosteroid and responded rapidly with a complete resolution of ascites and the abdominal pain.