UBCG: Up-to-date bacterial core gene set and pipeline for phylogenomic tree reconstruction

나성인,김영욱,윤석환,하성민,백인우,천종식 한국미생물학회 2018 The journal of microbiology Vol.56 No.4

Genome-based phylogeny plays a central role in the future taxonomy and phylogenetics of Bacteria and Archaea by replacing 16S rRNA gene phylogeny. The concatenated core gene alignments are frequently used for such a purpose. The bacterial core genes are defined as single-copy, homologous genes that are present in most of the known bacterial species. There have been several studies describing such a gene set, but the number of species considered was rather small. Here we present the up-to-date bacterial core gene set, named UBCG, and software suites to accommodate necessary steps to generate and evaluate phylogenetic trees. The method was successfully used to infer phylogenomic relationship of Escherichia and related taxa and can be used for the set of genomes at any taxonomic ranks of Bacteria. The UBCG pipeline and file viewer are freely available at https://www.ezbiocloud.net/ tools/ubcg and https://www.ezbiocloud.net/tools/ubcg_viewer, respectively.

[외국정책사례] 일본 지자체의 탈탄소정책 현황과 과제

나성인 한국주민자치학회 2022 월간 공공정책 Vol.202 No.-

Post-2012 기후변화체제와 한국의 협상전략

나성인 한국무역통상학회 2009 무역통상학회지 Vol.9 No.1

This paper examines Korea’s negotiation strategy in Post-2012 global climate regime beyond 2012. Negotiations for the future climate regime beyond 2012 started at COP11 and COP/MOP1, held in 2005. It is necessary to overcome various difficulties such as participation of the US and developing countries for GHG emissions reduction for midand long-term climate governance. This paper analyzed critical issues in international negotiation to form global climate regime beyond 2012 by analysing the UNFCCC and Kyoto Protocol. Korea has been treated as a non-Annex I country that is not assigned a quantified emission limitation; however, there is high expectation and pressure from international society to take on such a limitation, in consideration of the country’s economic growth. Mr. Ban Kimoon, newly appointed as Secretary General of the UN, may also compel the Korean government to take some action in this matter. This paper examines Korea’s negotiation strategies based on various indexes developed for proposals on future climate regime and.First, Korea is the world’s 10th largest GHG emissions country as of 2004, and has the 23rd largest cumulative GHG emissions from 1990 to 2000. Second, Korea has the world’s 30th highest per capita GDP in 2002, and was 24th in per capita CO2emissions,while it was 60th in per capita cumulative CO2 emissions from 1990 to 2000. Third, Korea’s HDI status was 32nd in 1990 with a rate of 0.814, improving to 28th in 2003 with a rate of 0.901. The socio-economic structure is quite similar to that of an industrialised country; thus, Korea’s responsibility toward the climate governance is high when we consider the series of indexes of GHG emissions. In conclusion, Korea government would not proactively take on the same level of obligations as developed countries, but would be likely to take on greater obligations than other developing countries. This paper examines Korea’s negotiation strategy in Post-2012 global climate regime beyond 2012. Negotiations for the future climate regime beyond 2012 started at COP11 and COP/MOP1, held in 2005. It is necessary to overcome various difficulties such as participation of the US and developing countries for GHG emissions reduction for midand long-term climate governance. This paper analyzed critical issues in international negotiation to form global climate regime beyond 2012 by analysing the UNFCCC and Kyoto Protocol. Korea has been treated as a non-Annex I country that is not assigned a quantified emission limitation; however, there is high expectation and pressure from international society to take on such a limitation, in consideration of the country’s economic growth. Mr. Ban Kimoon, newly appointed as Secretary General of the UN, may also compel the Korean government to take some action in this matter. This paper examines Korea’s negotiation strategies based on various indexes developed for proposals on future climate regime and.First, Korea is the world’s 10th largest GHG emissions country as of 2004, and has the 23rd largest cumulative GHG emissions from 1990 to 2000. Second, Korea has the world’s 30th highest per capita GDP in 2002, and was 24th in per capita CO2emissions,while it was 60th in per capita cumulative CO2 emissions from 1990 to 2000. Third, Korea’s HDI status was 32nd in 1990 with a rate of 0.814, improving to 28th in 2003 with a rate of 0.901. The socio-economic structure is quite similar to that of an industrialised country; thus, Korea’s responsibility toward the climate governance is high when we consider the series of indexes of GHG emissions. In conclusion, Korea government would not proactively take on the same level of obligations as developed countries, but would be likely to take on greater obligations than other developing countries.

목동맥 석회화죽상경화판에서 발생한 동맥-동맥색전증의 조직학적 확증

나성인,류한욱,이찬혁,장혁수,이설원,양태호,곽효성,정경호,정슬기 대한신경과학회 2016 대한신경과학회지 Vol.34 No.2

Artery to artery embolism is one of the main causes of cerebral infarction, and it can originate from many locations. Here we report a case of cerebral infarction in which calcified cerebral emboli were detected in brain computed tomography (CT). The calcified emboli were thought to originate from a carotid plaque that showed calcification and ulceration. We present histologic and micro-CT findings of a carotid plaque as a source of artery to artery embolism.

홍국쌀로 제조한 식혜의 품질특성에 관한 연구

나성주(Sung Ju Na),최상호(Sang Ho Choi),이선호(Sun Ho Lee),안종성(Jong Sung Ahn),김정수(Jung Soo Kim) 한국조리학회 2013 한국조리학회지 Vol.19 No.3

This study investigates the quality characteristics of Sikhye, a Korean traditional drink, made with different amounts of Monascus anka rice, or red yeast rice, and the results are as follows. During the saccharification process of red yeast rice, there was not significant change in pH, and its sugar content increased. It revealed that the optimal hours of saccharification for making Sikhye were four or five hours, which showed the highest in ° Brix. PH decreased significantly with increasing amounts of red yeast rice, and there was no change in sugar content and reducing sugar. Chromaticity L values decreased with increasing amounts of red yeast rice, and a value, b value and the turbidity increased. DPPH free radical scavenging activity of the samples showed significant differences in the samples with high scores as the amounts of red yeast rice increased. As a result of measuring the total microorganism number of the sample stored at 4℃, storability was improved with increasing amounts of red yeast rice. Preference was high in the order of 40%, 50%, 30%, 20%, 0%, and 10%, and the optimal amount of red yeast rice was less than 40-50%. Adding red yeast rice showed high scores in the sensory test, showing red color in Sikhye. In addition, its antioxidative activity effect and microbial growth inhibitory activity were considered to improve storability and preference.

The development of hepatocellular carcinoma during long-term treatment for recurrent non-small cell lung cancer: a case report

나성균,강성희 대한간암학회 2023 대한간암학회지 Vol.23 No.1

Multiple primary malignancies (MPMs) are defined as the presence of two or more malignancies in different organs, without a subordinate relationship. Although rarely reported, hepatocellular carcinoma (HCC) occasionally presents with simultaneous or metachronous primary malignancies in other organs. In this report, we describe a patient with lung adenocarcinoma and lymph node and bone metastases, treated with five chemotherapeutic regimens for 24 months. Changing the chemotherapy regimen based on the suspicion of metastasis of a new liver mass did not lead to improvements. This prompted a liver biopsy and a revised diagnosis of HCC. Sixth-line treatment with the concurrent use of cisplatin-paclitaxel for lung cancer and sorafenib for HCC, stabilized the disease. The concurrent treatment was not tolerated and was discontinued owing to adverse events. Considering our findings, treatment with increased efficacy and lower toxicity for MPMs is warranted.

대망막 폐흡충증 1예

나성일,김승수,이동민,이상일,윤일용,김지혜,채제건,이흥범,이용철,이양근 대한감염학회 2002 Infection and Chemotherapy Vol.34 No.3

와이파이(Wi-Fi)의 효율적 확산전략 연구

나성욱,강경훈,정종열 한국통신학회 2013 정보와 통신 Vol.30 No.6

와이파이(Wi-Fi) 기술은 무선 데이터 트래픽 폭증에 따라 사업자에게는 트래픽 우회, 이용자에게는 통신요금 부담 완화의 대안으로 중요성이 부각되고 있다. 이에 우리나라에서는 이동통신사업자 중심으로 와이파이를 지속적으로 확충하여 세계에서 가장 많은 와이파이 존(zone)을 보유한 국가가 되었다. 그러나, 특정 장소에 와이파이를 중복적으로 구축함에 따라 투자 효율성과 서비스 품질이 저하되고, 서민·소외계층 이용시설에는 구축이 상대적으로 저조하다는 문제점도 상존하는 상황이다. 본 고에서는 우리나라의 와이파이를 효율적으로 확산하고자 3가지 개선방향을 제시하였다. 첫 번째는 경쟁구축·차별화에서 투자효율화·공동이용 전략으로의 전환이며, 두 번째는 수도권·도시 지역 중심에서 서민·소외계층 지역으로 확산시키는 것이다. 마지막으로 Legacy Wi-Fi에서 차세대 Wi-Fi로 전환하는 것을 주요 방향으로 제시하였고, 이러한 개선방향을 바탕으로 4가지 전략을 제시하였다. 첫 번째 전략은 PPP(Public Private Partnership) 방식의 공공와이파이(Public Wi-Fi) 구축으로, 전통시장, 복지시설 등 서민·소외계층이 주로 이용하며 와이파이 구축이 열악한 이용시설에 정부, 지자체, 통신사가 공동으로 투자하여 공공와이파이를 구축함으로써 정보격차를 해소시키는 것이다. 두 번째 전략은 통신사의 와이파이 개방을 통한 공용화로, 통신사가 공공장소에 기 구축한 와이파이의 개방을 유도함으로 써 중복투자 및 서비스 품질 저하 방지 등 공용화를 통한 투자효율성을 제고하는 것이다. 세 번째 전략은 차세대 와이파이 선도 도입을 통한 글로벌 경쟁력 강화로, LTE 등 이동통신 기술의 급속한 보급에 맞추어 무선랜 서비스의 경쟁력 확보를 위해 광대역화·광역화를 선도하고, 응용서비스 발굴 및 산업활성화를 유도하는 것이다. 마지막은 공공와이파이 인식제고로, 공공와이파이의 이용편의성과 홍보활동을 강화하는 것이다. 이러한 전략의 핵심은 공공와이파이 확산과 차세대 와이파이 선도 도입으로, 이를 통하여 통신복지를 실현하고, 산업활성화를 통한 국민행복을 실현시키는 것에 대하여 간략히 설명한다.

여러 서버배정방식의 멀티클래스 손실시스템 연구

나성룡,Na, Seongryong 한국통계학회 2016 응용통계연구 Vol.29 No.4

이 논문에서는 서로 다른 서버배정방식을 가지는 멀티클래스 손실시스템을 연구한다. 마코프 성질을 유지하도록 상태를 정의하고 상태를 효율적으로 표현하는 방법을 살펴본다. 시스템 성능척도를 산출하기 위하여 마코프 성질에 기초한 극한확률 유도를 연구한다. 해석해 혹은 수치해를 구하여 배정방식이 시스템 성능에 미치는 영향을 비교한다. In this paper, we study multiclass loss systems with different server allocation methods. The Markovian states of the systems are defined and their effective representation is investigated. The limiting probabilities are derived based on the Markovian property to determine the performance measures of the systems. The effects of the assignment methods are compared using numerical solutions.

국세-지방세 조정을 통한 지방세제 개선방안의 모색

나성린 ( Seong Lin Na ) 한양대학교 경제연구소 2007 경제연구 Vol.28 No.2