PCI시술시 혈소판 당단백 GP IIb/IIIA 억제제(Abciximab) 투여의 경제적 가치

김진현,신상진,김은주,이영희,Kim, Jin-hyun,Shin, Sang-Jin,Kim, Eun-Ju,Lee, Young-Hee 대한약학회 2007 약학회지 Vol.51 No.3

This study was performed to analyse the economic value of abciximab which is used in PCI to prevent high-risk patients with ischemic complications. The effectiveness of abciximab was extracted from published clinical trials by search-ing CCIS, and the direct medical costs relevant to using abciximab were estimated from the NHI claims database. The results in terms of cost per life-year gained (LYG) and cost per QALY gained showed that abciximab was cost-effective enough to deserve its cost. Social net benefit resulting from abciximab in PCI was estimated to be 60-70 billion Won per year.

건강보험 한방의료의 총액계약제 도입방안

김진현,김은혜,김윤희,Kim, Jin-Hyun,Kim, Eun-Hye,Kim, Yoon-Hee 대한예방한의학회 2010 대한예방한의학회지 Vol.14 No.1

Objectives : This paper recommends a global budget based payment system for reimbursing oriental medical services in the national health insurance. Methods : We analyzed previous research outcomes related to oriental medical services and payment system We reviewed the experiences of other countries' global budget system in terms of their strength and weakness. In addition, we developed a reimbursement method for oriental medical services based on global budget. Results : Our reviews focused on global budget system of Germany, the Netherlands, the United Kingdom, Canada, France, and Taiwan. The estimation of global budget in the national health insurance was described in two scenarios. First scenario was to allocate oriental medical services in scale after signing a contract for global budget. In this case, 4.16% of the national health insurance expenditure was allocated for the oriental medical services. Second scenario was to estimate the global budget in a historical context. As a result, the first scenario in total budget was higher than the second, and we proposed a retrospective adjustment method for the gap between the budget and the actual expenditure Conclusions : The payment system for oriental medical services is recommended to shift from fee-for-service to global budget.

한약-양약 병용 투여에 관한 논문 동향 분석

김진현,김철,김상균,장현철,한정민,예상준,송미영,Kim, Jin-Hyun,Kim, Chul,Kim, Sang-Kyun,Jang, Hyun-Chul,Han, Jeong-Min,Yea, Sang-Jun,Song, Mi-Young 대한예방한의학회 2009 대한예방한의학회지 Vol.13 No.3

Objectives : In this study, we survey papers about the combined therapy of oriental medicine and western medicine in oriental medicine viewpoint. Methods : First, we collected research papers on combined treatment, and we found 70 papers in the two internet sites, 'OASIS' and 'KISTI', using the keywords 'combined treatment', 'collaborated diagnosis', 'oriental-western medicine', and 'western-oriental medicine'. Then we analyzed them according to year, oriental-western medicine, diseases, research methods and subjects. Results & Conclusions : Researches for combined therapy had some problems as follows : First, studies have been made only for limited diseases like cancer, infection, stroke, etc. Second, methods of research are also limited. Some methods such as in vivo, in vitro and case-report are used repeatedly. Third, only the positive aspects of the combined therapy are proposed. We don't find the side effects of the combined therapy at all. To solve these problems, more objective and balanced studies such as RCT for various diseases should be performed.

공동주택 마감공사의 하자위험도 평가에 관한 연구

김진현,고성석,Kim, Jin-Hyun,Go, Seong-Seok 한국건설관리학회 2012 한국건설관리학회 논문집 Vol.13 No.6

The apartment house taking most part of our housing types was facing the limit of consumption from the housing supply-oriented policy in the past of rapid urbanization resulting in being transferred to the housing supply-oriented one. Accordingly the requirement for housing quality by customers is diversified varied, in order to meet this the effective and systematic quality control for preventing the defects from the stage of building is required. In this study for the effective and systematic quality management for defects of apartment house analysis on the frequencies and loss expenses from defective maintenance regarding examples of apartment houses having been moved in within five years recently, and the survey on their dwellers' consciousness were made, and the table for quantified apartment house defective risk. 우리나라 주택유형 가운데 대부분을 차지하는 공동주택은 급격한 도시화가 진행됐던 과거, 공급위주에서 소비물량의 한계에 직면하며 수요중심으로 전환되었다. 따라서 주택품질에 대한 소비자의 요구도는 다양화 다변화되고 있으며, 이를 충족시키기 위해서는 건설단계에부터 하자 예방을 위한 효율적이고 체계적인 품질관리가 요구된다. 이에 본 연구에서는 공동주택 하자의 효율적이고 체계적인 관리를 위해 최근 5년 이내 입주가 완료된 공동주택 사례를 대상으로 발생빈도 및 하자보수 손실비용 분석과 거주자 만족도조사를 실시하여 보정 및 수치화에 의한 정량적 공동주택 하자 위험성 평가표를 구축 제시하였다.

광탄성법에 의한 러그달린 구동윤하의 (驅動輪下) 응력분포에 관한 해석

김진현,최상인 ( Jin Hyun Kim,Sang In Choi ) 한국농업기계학회 1983 바이오시스템공학 Vol.8 No.2

산재 사망십만인률 국제비교와 관련된 한계점 고찰

김진현,서동현,강성윤,백빛나,배계완,Kim, Jin Hyun,Seo, Dong-Hyun,Kang, Sung yun,Baek, Bitna,Bae, Gye wan 한국안전학회 2021 한국안전학회지 Vol.36 No.4

This study analyzes the differences in definitions and concepts of terms used in the statistical indicators of fatal occupational injuries per 100,000 workers among countries included in the ILOSTAT data explorer. In addition, improvement measures focusing on the limitations in international comparison are proposed. Five countries-the Republic of Korea, Germany, Japan, United Kingdom, United States-- were comparatively analyzed. These countries were selected according to the significance of differences in their definitions of workplace injuries, workers, and compensation insurance, and their reporting systems. Considering these differences before directly comparing statistical indicators of fatal occupational injuries per 100,000 workers among countries is necessary because the range of comparison groups and the definition of fatal occupational injury are different for each country. While one can also compare trends by country, it is necessary to investigate beforehand whether the criteria and methods for processing statistics have changed. Misinterpretation can be minimized by properly understanding the process and limitations of fatal occupational statistical indicators that may differ from country to country.

맵리듀스 프레임웍 상에서 맵리듀스 함수 호출을 최적화하는 순차 패턴 마이닝 기법

김진현,심규석,Kim, Jin-Hyun,Shim, Kyu-Seok 한국정보처리학회 2011 정보처리학회논문지D Vol.18 No.2

시퀀스(sequence) 데이터가 주어졌을 때 그 중에서 빈번(frequent)한 순차 패턴을 찾는 순차 패턴 마이닝(sequential pattern mining)은 여러 어플리케이션(application)에 사용되는 중요한 데이터마이닝 문제이다. 순차 패턴 마이닝은 웹 접속 패턴, 고객 구매 패턴, 특정 질병의 DNA 시퀀스를 찾는 등 광범위한 분야에서 사용된다. 본 논문에서는 맵리듀스(MapReduce) 프레임웍 상에서 맵리듀스 함수 호출을 최적화하는 순차 패턴 마이닝 알고리즘을 개발하였다. 이 알고리즘은 여러 대의 기계에 데이터들을 분산시켜 병렬적으로 빈번한 순차 패턴을 찾는다. 실험적으로 다양한 데이터를 이용하여 파라미터 값을 변화시켜가며 제안된 알고리즘의 성능을 종합적으로 확인하였다. 그리고 실험 결과를 통해 제안된 알고리즘은 기계 수에 대해 선형적인 속도 개선을 보인다는 것을 확인하였다. Sequential pattern mining that determines frequent patterns appearing in a given set of sequences is an important data mining problem with broad applications. For example, sequential pattern mining can find the web access patterns, customer's purchase patterns and DNA sequences related with specific disease. In this paper, we develop the sequential pattern mining algorithms using MapReduce framework. Our algorithms distribute input data to several machines and find frequent sequential patterns in parallel. With synthetic data sets, we did a comprehensive performance study with varying various parameters. Our experimental results show that linear speed up can be achieved through our algorithms with increasing the number of used machines.

알파술폰화 고급지방산 메틸 에스테르의 공업적 합성

김진현,최성옥,윤영균,남기대 ( Jin Hyun Kim,Seung Ok Choi,Young Kyun Yun,Ki Dae Nam ) 한국공업화학회 1998 공업화학 Vol.9 No.4

한의사인력의 중장기 수급 추계 연구

김진현,배현지,이선동,Kim, Jin-Hyun,Bae, Hyun-Ji,Lee, Sun-Dong 대한예방한의학회 2013 대한예방한의학회지 Vol.17 No.1

Objectives : This study was conducted to estimate the future demand and supply of physicians for korean medicine from 2016 year to 2026 year in order to make an adequate manpower policy in a way of keeping a balance between demand and supply. Methods : Baseline projection method and trend analysis(a polynomial log power equation model) were used in the estimation of future supply and demand respectively. We used data about the amount of oriental doctors from Ministry of Health and Welfare Statistics Yearbook and the treatment days from HIRA Statistics Yearbook. Results : It was projected that the total number of physician of Korean medicine will be 25,178 registered and 18,967 available in clinical setting. According to polynomial equation model which explained the trend of demand and had the highest score of $R^2$ among the equation models, 3,800~5,600 physician in Korean medicine will be oversupplied in 2016 year, 9,000~10,700 physicians in 2021 year and 15,700~17,000 persons in 2026 year depends on annual working days which is 265days, 255days or 239days. Log equation model also showed that overall excess supply of physician manpower in Korean medicine. Conclusions : Alternative manpower policies for Korean medicine doctors should be implemented in a way of both dwindling supplies and growing demand in Korean medical service in terms of Korean medical services utilization and improving physician's productivity.

바이오매스로부터 파클리탁셀 회수를 위한 전통적 용매 추출, 마이크로웨이브를 이용한 추출, 초음파를 이용한 추출 방법 비교

김진현,Kim, Jin-Hyun 한국화학공학회 2020 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.58 No.2

본 연구에서는 바이오매스로부터 파클리탁셀 회수를 위한 전통적 용매 추출(conventional solvent extraction, CSE), 마이크로웨이브를 이용한 추출(microwave-assisted extraction, MAE), 초음파를 이용한 추출(ultrasound-assisted extraction, UAE) 방법을 비교하였다. 추출 용매 종류(아세톤, 클로로포름, 에탄올, 메탄올, 메틸렌 클로라이드)에 따른 영향을 조사한 결과, 메탄올이 모든 추출 방법에서 가장 적합하였다. 메탄올을 이용한 MAE와 UAE의 경우, 단 1회의 추출로 대부분의 파클리탁셀 회수(>95%)가 가능하였다. 또한 MAE와 UAE의 경우 추출 온도(25-45 ℃), 마이크로웨이브 파워(50-150 W), 초음파 파워(180-380 W)의 증가에 따라 파클리탁셀 회수율이 증가하였다. 또한 SEM 분석을 통해 바이오매스 표면을 조사한 결과, 표면 구조가 CSE의 경우에는 조금 주름진 형태를 보인 반면 MAE와 UAE의 경우에는 강한 충격으로 매우 거칠고 파괴된 형태를 보였다. In this study, conventional solvent extraction (CSE), microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE) were compared for the recovery of paclitaxel from biomass. As a result of investigating the effect of the extraction solvent type (acetone, chloroform, ethanol, methanol, methylene chloride), methanol was the most suitable for all extraction methods. In the case of MAE and UAE using methanol, most of the paclitaxel (> 95%) was recovered by only one extraction. The recovery rate of paclitaxel increased with the increase of extraction temperature (25-45 ℃), microwave power (50-150 W), and ultrasonic power (180-380 W) for MAE and UAE. In addition, SEM analysis showed that the biomass surface structure was slightly corrugated in CSE, while in the MAE and UAE, it was very rough and destroyed by strong impact.