Vitamin C가 방사선과 Aflatoxin B₁을 처리한 흰쥐의 간세포에서 Aflatoxin B₁-DNA Adduct 형성에 미치는 영향

김소영,김한수,강진순,Kim, Soyoung,Kim, Hansoo,Kang, Jin-Soon 한국식품저장유통학회 2014 한국식품저장유통학회지 Vol.21 No.5

본 연구는 흰쥐에게 $AFB_1$을 투여하거나 방사선과 $AFB_1$을 병합처리함으로 유발된 흰쥐의 간세포에서의 $AFB_1$-DNA 부가체의 형성과 세포의 산화적 손상에 대한 vitamin C의 효과를 조사하기 위하여 수행되었다. X-ray 조사는 실험기간 내 단 1회로 실험사육기간 1일에 조사 하였고 X-ray 조사 후 vitamin C를 투여하였으며 vitamin C 투여 1시간 후 $AFB_1$을 투여하였다. Vitamin C와 $AFB_1$은 모두 복강투여로 실험 사육 첫 일부터 1회 시작하여 3일에 한번씩, 5회 반복 투였으며 실험동물 사육기간은 총 15일로 하였다. ELISA에 의한 흰쥐의 혈청 내 $AFB_1$ 잔여 농도는 $AFB_1$ 단독 투여군에서 $5.17{\pm}0.34ng/mL$이었으나 여기에 vitamin C 혼합 투여군에서는 $3.23{\pm}0.76ng/ml$가 검출되었다. 간세포의 $AFB_1$-DNA adduct 농도는 $AFB_1$ 단독 투여군에서는 $9.38{\pm}0.41ng/mL$이었으며 2군에 vitamin C를 함께 투여한 3군에서는 $5.28{\pm}0.32ng/ml$로 나타나 2군에 비해 유의적으로(p<0.001) 44% 감소한 양상을 나타내었다. 한편 X선 조사와 $AFB_1$ 병합처리한 4군에 비해 4군에 vitamin C를 투여한 5군에서 혈청 내 $AFB_1$ 함량과 간세포의 $AFB_1$-DNA adduct 함량이 다소 감소하였으나 유의적인 차이는 없었다. 또한 면역조직화학적 관찰에서 $AFB_1$ 단독 투여군에서는 중심정맥과 혈관주변에서 $AFB_1$ 축적이 관찰되었는데 이러한 현상은 vitamin C를 혼합 투여함으로써 중심정맥과 혈관 주변의 갈색 침전이 현저하게 감소한 것으로 나타났다. 그러나 X선 조사와 $AFB_1$ 병합 처리한 군에서는 그 정도가 약했다. The objective of this study was to examine the effects of vitamin C on the formation of aflatoxin $B_1$ ($AFB_1$)-DNA adduct and $AFB_1$-induing cellular oxidative damage in rat livers treated with radiation and $AFB_1$. Six-week-old male Sprague-Dawley rats were randomly divided into five groups: the control group, the $AFB_1$-treated group, the group treated with $AFB_1$ and vitamin C, the group treated with X-ray and $AFB_1$, and the group treated with X-ray and $AFB_1$ with vitamin C. On the first day of the experiment, only one dose of X-rays was exposed to the entire liver at 1,500 cGy. Next, vitamin C was injected at 10 mg/kg body weight via intraperitoneal injection, followed an hour later by the administration of 0.4 mg/kg of $AFB_1$ via intraperitoneal injection. These treatments were administered every three days for 15 days. On the 16th day, the animals were sacrificed. The $AFB_1$ contents of the rat sera were determined via indirect competitive ELISA. In the quantitative analysis of $AFB_1$ in the rat sera via ELISA, $5.17{\pm}0.34ng/mL$ of $AFB_1$ was detected in the $AFB_1$-treated groups, but the amount decreased more significantly to $3.23{\pm}0.76ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. The effect of vitamin C on $AFB_1$-DNA adduct formation was determined via ELISA. The values of $AFB_1$-DNA adduct formation were $9.38{\pm}0.41ng/mL$ in the $AFB_1$-treated groups, but the amount decreased more significantly to $5.28{\pm}0.32ng/mL$ in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. Immunohistochemistry revealed that the accumulation of the $AFB_1$ was not observed in the normal liver tissue (G1). The $AFB_1$-positive materials were observed in the central vein and the portal vein of the liver tissue from the $AFB_1$(G2) treatment or the X-ray and $AFB_1$(G4) co-treatment, but the $AFB_1$-positive materials were observed weakly in the group treated with vitamin C (G3 and G5). These results indicate that vitamin C had ameliorating effects on the $AFB_1$ accumulation of liver tissue.

The Study on the Semantic Function of Korean Distributive Plural Marker-tul

김소영 ( Kim¸ Soyoung ) 현대영미어문학회 2018 현대영미어문학회 추계학술대회 발표논문집 Vol.2018 No.-

태양광 물 분해를 통한 수소 생산용 Cu₂O/CuO 이종접합 광전극의 제작 및 광전기화학적 특성

김소영,김효진,홍순구,김도진,Kim, Soyoung,Kim, Hyojin,Hong, Soon-Ku,Kim, Dojin 한국재료학회 2016 한국재료학회지 Vol.26 No.11

We report on the fabrication and characterization of a novel $Cu_2O/CuO$ heterojunction structure with CuO nanorods embedded in $Cu_2O$ thin film as an efficient photocathode for photoelectrochemical (PEC) solar water splitting. A CuO nanorod array was first prepared on an indium-tin-oxide-coated glass substrate via a seed-mediated hydrothermal synthesis method; then, a $Cu_2O$ thin film was electrodeposited onto the CuO nanorod array to form an oxide semiconductor heterostructure. The crystalline phases and morphologies of the heterojunction materials were examined using X-ray diffraction and scanning electron microscopy, as well as Raman scattering. The PEC properties of the fabricated $Cu_2O/CuO$ heterojunction photocathode were evaluated by photocurrent conversion efficiency measurements under white light illumination. From the observed PEC current density versus voltage (J-V) behavior, the $Cu_2O/CuO$ photocathode was found to exhibit negligible dark current and high photocurrent density, e.g. $-1.05mA/cm^2$ at -0.6 V vs. $Hg/HgCl_2$ in $1mM\;Na_2SO_4$ electrolyte, revealing the effective operation of the oxide heterostructure. The photocurrent conversion efficiency of the $Cu_2O/CuO$ photocathode was estimated to be 1.27% at -0.6 V vs. $Hg/HgCl_2$. Moreover, the PEC current density versus time (J-T) profile measured at -0.5 V vs. $Hg/HgCl_2$ on the $Cu_2O/CuO$ photocathode indicated a 3-fold increase in the photocurrent density compared to that of a simple $Cu_2O$ thin film photocathode. The improved PEC performance was attributed to a certain synergistic effect of the bilayer heterostructure on the light absorption and electron-hole recombination processes.

신규간호사의 재직의도와 현실충격 및 극복력

김소영,현명선,Kim, Soyoung,Hyun, Myung-Sun 한국콘텐츠학회 2022 한국콘텐츠학회논문지 Vol.22 No.10

The purpose of this study was to identify factors influencing intention to stay among new graduate nurses. The participants were 127 new graduate nurses working at A University hospital in Gyeonggi Province. Data were analyzed by descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficient, and multiple regression. The results showed that job satisfaction, reality shock, working period, and resilience were significant predictors of intention to stay and explained for 44.2% of the variance in intention to stay. The findings of this study suggest that interventions focusing on reducing the reality shock through pre-experiences or trainings in clinical situations and enhancing the resilience are needed to improve intention to stay for the new graduate nurses. Also it is necessary to establish a support system and work environment to improve nursing job satisfaction, and a long-term education program of more than 6 months is needed to help new nurses adapt to work.

올레핀 촉진수송 분리막용 AgCF₃SO₃를 활용한 PEBAX-2533/Ag Salt/Al(NO₃)₃ 복합체

김소영,강상욱,Kim, Soyoung,Kang, Sang Wook 한국막학회 2021 멤브레인 Vol.31 No.1

본 연구는 현재 올레핀/파라핀 분리에서 사용되는 극저온 분리법을 대체하기 위한 촉진수송 분리막에 대한 연구이다. 촉진수송 분리 막을 상업화하기 위해서는 비용 절감 또한 매우 중요한 요소이다. 하지만 많은 연구가 이루어지고 있는 AgBF4는 상대적으로 고가인 은 염이기 때문에 이를 대체하기 위해 비교적 저렴한 AgCF3SO3를 이용하여 PEBAX-2533/AgCF3SO3/Al(NO3)3 복합막을 제조하였다. 분리막의 특성은 SEM, FT-IR, RAMAN을 통해 분석되었으며, 이번 연구를 통해 고분자 매트릭스가 장기 안정성에 영향을 준다는 사실을 확인하였다. This study was a study on an facilitated transport membrane to replace the cryogenic separation method currently used in olefin/paraffin separation. Cost reduction is also a very important factor to commercialize facilitated transport membranes. However, AgBF4, which has been studied a lot, is a relatively expensive silver salt. To replace this, a PEBAX-2533/ AgCF3SO3/Al(NO3)3 composite film was prepared using relatively inexpensive AgCF3SO3. It was analyzed through SEM, FT-IR, and RAMAN. Through this study, it was confirmed that the polymer matrix affects the long-term stability.

자본시장의 글로벌화와 한국 통화정책의 독립성

김소영,신관호,Kim, Soyoung,Shin, Kwanho 한국개발연구원 2010 韓國 開發 硏究 Vol.32 No.2

본 논문은 한국이 1997년 외환위기 이후 변동환율제 도입과 더불어 자본자유화로 자본시장이 글로벌화된 상황에서 외부로부터 독립적인 통화정책을 유지할 수 있었는지를 자본자유화 이전 기간과 비교하여 분석했다. 트릴레마 이론에 비추어보면, 자본자유화 이전에는 환율시장에 적극적으로 개입을 해도 이론적으로 독립적인 통화정책을 유지할 수 있는 여지가 있었으며, 자본자유화 이후에는 환율제도가 자유변동환율제도로 전환함에 따라 독립적인 통화정책을 유지할 수 있는 여지가 있었다. 하지만 한국과 같은 소규모 개방경제의 경우 자본시장이 완전히 개방되어 국가 간 연계성이 증가하고, 막대한 양의 국제자본 유출입이 발생하여 환율과 자산 시장의 심각한 불안정성을 초래할 수 있으므로 외국의 통화정책과 자본 흐름으로부터 완전히 자유로운 통화정책을 집행하기 어려울 수 있다. 본 논문의 실증분석에서는 부를 미국으로 국한하여 한국의 통화정책이 미국의 통화정책으로부터 독립적인지 블록 외생성 구조 VAR 모형을 이용하여 자세히 분석하였다. 그 결과 한국의 통화정책이 자본자유화 이전과 이후 두 기간 모두에서 미국의 통화정책으로부터 완전히 독립적으로 운용되지 못하였던 것으로 보인다. 자본자유화 이후 기간의 경우 완전한 변동환율제를 실제로 운용하기는 쉽지 않았고, 이로 인해 필연적으로 한국의 통화정책은 외부의 충격으로부터 완전히 독립적이지 못했던 것으로 보인다. 또한 자본자유화 이후 기간에는 포트폴리오 자본의 유출입이 자본자유화 이전 기간에 비해 매우 민감하게 변화하여 독립적인 통화정책의 운영에 어려움을 초래한 것으로 보인다. 따라서 향후 자본의 글로벌화에 효과적으로 대응하면서 통화정책을 독립적으로 유지할 수 있는 정책의 틀을 개발하는 것이 시급하다고 하겠다. This paper empirically examines whether Korean monetary policy is independent of U.S. monetary policy during the post-crisis period in which capital account is liberalized and floating exchange rate regime is adopted and during the pre-crisis period in which capital mobility is restricted and tightly managed exchange rate regime is adopted. Before capital account liberalization, monetary autonomy can be achieved in view of the trillema, even under tightly managed exchange rate regime, as capital mobility is restricted. On the other hand, for the period after capital account liberalization, monetary autonomy can be also achieved in view of the trillema, as exchange rate stability is given up. Securing monetary autonomy, however, may not be easy under liberalized capital account for a small open economy like Korea. Huge capital movements can generate excessive instability in foreign exchange and asset markets. Strengthened international economic linkages may also be another factor to prevent monetary policy from being independent. Using block-exogenous structural VAR model, the effects of U.S. monetary policy shocks on Korean economy are examined. Empirical results show that Korean monetary policy is not independent of U.S. monetary policy for both periods before and after capital account liberalization. For the period after capital account liberalization, Korea does not seem to have implemented floating exchange rate policy in practice, which may lead Korean monetary policy to be dependent on U.S. monetary policy. For the period after capital account liberalization, portfolio flows respond dramatically to the U.S. monetary policy, which may also keep Korean monetary policy from being independent.

초･중･고 학교급별 학부모 학교참여 관련요인

김소영,진미정,Kim,Soyoung,Chin,Meejung 한국가족학회 2015 가족과 문화 Vol.27 No.2

본 연구의 목적은 초･중･고등학생 학부모의 학교참여 수준에 차이가 있는지 조사하고, 학 교급별로 학부모의 학교활동 참여와 관련이 있는 사회‧인구학적 요인, 자녀 관련 요인, 참여 동기 요인을 밝히고자 하는 것이다. 이를 위해 첫 자녀가 전국 초･중･고등학교에 재학 중인 학부모 1,500명의 설문조사 자료를 활용하여 기술통계분석, 일원분산분석, 위계적 다중회귀 분석을 실시한 결과는 다음과 같다. 첫째, 초등학생 학부모의 학교참여정도가 중･고등학생 학부모에 비해 유의미하게 높았다. 둘째, 초등학생과 중학생 학부모는 아버지에 비해 어머니 가, 학력과 가구소득이 높을수록, 대도시보다는 중소도시나 읍면지역에 거주할 때 학교참여 활동이 활발한 반면, 고등학생 학부모에게서는 사회‧인구학적 특성에 따라 학교참여에서 차이가 나타나지 않았다. 다만 맞벌이인 학부모는 모든 학교급에서 학교참여 정도가 낮았다. 셋째, 자녀 관련 요인 중에서는 성적만이 유일하게 초등학생 학부모의 학교활동 참여와 관련이 있었다. 넷째, 학부모의 학교참여 동기는 모든 학교급에서 학교참여를 결정하는 중요한 요인으로 밝혀졌으나, 학교급에 따라 영향을 미치는 동기는 달라지는 것으로 나타났다. 이러한 연구결과를 바탕으로 초등학교, 중학교, 고등학교에서 학부모의 학교참여를 독려하기 위해 맞춤화된 전략을 수립할 수 있을 것으로 기대한다. The purpose of this study was to investigate the sociodemographic, child-related, and motivational factors that were associated with parents' participation in school-based involvement, and find out whether the association differed among parents of elementary, middle and high school students. Findings from the analysis of data from a total of 1,500 parents who had at least one child in elementary, middle or high schools were as follows. Firstly, parents of elementary school students were more active in school-based involvement than parents of middle or high school students. Secondly, among parents of elementary and middle school students, mothers who were better educated, more affluent, and resided in small and medium sized cities tended to be more involved in school-based activities, whereas such factors rarely predicted parental involvement of high school students. Maternal employment was negatively associated with parental school-based involvement in all schools. Thirdly, out of child-related factors, only the child's school grades were associated with school-based involvement for parents of elementary school students. Fourthly, psychological motivations turned out to be the most powerful predictors of school-based involvement for parents of students in all ages, but different motivations functioned behind parental involvement in different school levels. Such findings are expected to contribute to developing customized strategies to promote parents' school-based involvement in elementary, middle, and high schools.

18세 이하 자녀를 둔 아버지의 가족식사시간과 생활만족도

김소영,Kim, Soyoung 대한가정학회 2017 Human Ecology Research(HER) Vol.55 No.5

This study examined the relationship between family meal time and emotional well-being for 5,186 fathers who were employed and had at least one child aged under 18 for the years 2009 and 2014 by analyzing their time diaries. In doing so, changes in time spent by fathers on family meals between 2009 and 2014 were also examined along with the factors associated with the amount of meal time for each year in order to understand ways to increase paternal participation in family meals. Analytic results showed that a father's family meal time had a positive association with his time use and life satisfaction; however, fathers who spent more than 40 minutes a day having meals with the family reported the highest score in time use and life satisfaction. The amount of time fathers spent on family meals increased from 38 minutes in 2009 to 43 minutes in 2014, whose change turned out to be mainly attributable to something more than the compositional change in the population between the two years, such as growing public awareness or cultural acceptance of the value of family meal. Fathers in dual-earner households tend to have longer family meal times; however, different factors were associated with their family meal times in 2009 and 2014. Policy implications are discussed in light of the government-initiated dining table education campaign to increase family meal time for the sake of children's character education at home.

냉감 소재를 활용한 밀착형 여성 스포츠 상의의 착용쾌적성 평가

김소영,최지영,이희란,홍경희,Kim, Soyoung,Choi, Jiyoung,Lee, Heeran,Hong, Kyunghi 한국의류학회 2017 한국의류학회지 Vol.41 No.5

This research investigated the effects of cool touch fabrics on thermo-regulating physical properties and subjective evaluation using a 3D fitted women's T-shirts in wear test. Qmax, clothing microclimate, microclimate wettedness, thermogram and subjective vote were observed during rest-right after an exercise-rest protocol. As a result, there was no single determining physical variable to explain the reasons of cool sensations of T-shirts made of cool touch fabric across the entire protocol. Qmax could partly predict a wear sensation at the initial stage when only insensible perspiration was presented. Simultaneous observation of temperature/humidity gradient understand from the inside to the outside of the clothing layer or microclimate wettedness calculated using vapor pressure were helpful to figure out the performance of cool touch fabric, especially at the later stage of the protocol when sweating was excessive. It was especially difficult to connect thermo-regulating physical variables to the subjective evaluation during transient conditions such as 'right after exercise' stage. It is necessary to measure the amount of heat and moisture transferred from the skin to the outside of clothing along with the physical properties measured in this study to understand the detailed mechanisms of why a cool sensation is evoked from tight fitting T-shirts made of newly developed cool touch fabrics.

윤치호의 ‘소사이어티(society)’ 개념 수용과 활동

김소영(Kim, Soyoung) 고려사학회 2018 한국사학보 Vol.- No.72

윤치호는 중국과 미국에서 유학하는 동안 근대적 지식을 습득하는 한편 실체로서 ‘소사이어티’를 경험하고 참여했다. 윤치호는 ‘소사이어티’를 ‘공공성’, ‘공익’을 실현하려는 목적을 가지고 결성된 단체, 또는 ‘공공성’, ‘공익’을 실현하기 위해 토론하고 공론을 형성해 가는 ‘공론장’으로 인식했다. 그는 귀국 후 1897년부터 7월부터 본격적으로 독립협회에 참여하여 토론회를 개설하는 등 협회의 성격을 ‘공론장’으로서 ‘사회단체’로 변화시켜 갔다. 윤치호를 비롯한 독립협회 세력은 ‘개화’라는 ‘공익’ 실현을 최우선, 최상위의 목적으로 설정하면서 ‘개화’에서 벗어나거나 방해가 되는 ‘사익’ 추구에 대해서는 부정적으로 인식했다. 즉 개개인의 ‘사익’을 인정하고 보호하기 위한 ‘사회’의 성립을 추구하면서도 ‘공익’을 ‘사익’보다 우선시 하며 ‘공익’에 해가 되는 ‘사익’을 부정하는 ‘양가성’을 보였다. 이와 같은 ‘사회’ 지향의 양가성은 1905년 이후 ‘국권’이 위태로워지는 상황에서 ‘민권’보다 ‘국권’을 우선시하는 인식과도 맞물렸다. 1900년대에 들어 윤치호의 일기에 등장하는 ‘사회’의 용례는 이전 시기와 마찬가지로 단체, 조직, 학회 등을 의미했다. 그는 을사늑약 체결 이후 ‘사회’를 통감부와 친일내각을 대신해 대한제국의 ‘개혁’을 추진하고 ‘국권’을 회복할 주체로 보고 다양한 ‘사회단체’ 활동을 전개했다. 1900년대 ‘사회’에 대한 논의는 주로 개인, ‘사회’, 국가의 상호관계를 중심으로 이루어졌다. 개인이 ‘사회’를 구성하고, ‘사회’의 확장 또는 집합이 국가라고 보았으나 국권 상실의 위기가 심화되면서 개인보다는 ‘사회’, ‘사회’보다는 국가를 우위에 두는 인식이 보편적이었다. 그 결과 각각의 ‘사회’가 추구해야 할 ‘공리’는 국가의 ’공리’에 기여하거나 합치되어야 ‘공익’으로서 인정받을 수 있었다. 당시 지식인들이 ‘공익’으로 규정한 것은 ‘부국강병’, ‘문명개화’였으며, 궁극적으로 ‘국권’을 회복하여 근대국가를 건설하는 것이었다. 독립협회와 이후 ‘사회단체’ 활동을 통해 윤치호가 추구했던 ‘공익’ 역시 동일한 내용이었다. 하지만 1910년 이후 일본제국의 식민지배가 지속되면서 윤치호는 ‘국권’ 회복이 아닌 ‘문명화’만을 ‘공익’으로 규정했고, 이를 실현하기 위해 식민권력과 타협하고 협력하는 ‘사회’ 활동을 전개했다. While studying in China and the United States, Yun Chi-ho acquired modern knowledge and experienced an entity of `Society`. He recorded diverse organizations using the word `society` in his diary. Japanese and Chinese intellectuals who came into contact with the West in the modern era began accepting Western societies as a group of people with a purposeful consciousness and translating them into various terms. Since then, the `society` of the West has gradually been translated into `Sahoe(社會)` in Chinese characters. Experiencing and participating `societies` in the United States, Yun Chi-ho also realized that many `societies` were formed with various purposes and they had one thing in common. In other words, he perceived that `society` was an organization formed with the purpose of realizing `public interests`, or `public sphere` which discusses and forms `public opinion` to realize `publicness` and `public interests`. Since returning home in 1897, Yun Chi-ho began to actively participate in Independence Club from July. He thought that many `societies` that had been experienced in America were also necessary for the reality of Joseon, and that conditions for `society` were already established in Joseon. It was expected that `society`, which had just begun to be established, would play a role of `public sphere` forming `public opinion`, and realize `public interests`.`Civilization and enlightenment` was defined as `public interests`. To realize these`public interests`,`society` required the government to reform or change to a more rational way of governance. The members of Independence Club including Yun Chi-ho recognized the realization of `public interests` as the highest priority and were negative for the pursuit of `private interests`. In other words, their aiming at society showed ambivalence that while pursuing the establishment of `society` to acknowledge and protect `individual interests`, `society` should pursue `public interests` rather than `individual interests`. This ambivalence was associated with the perception that `national right` was more important than `civil rights` in the situation where `national right` was at stake since 1905.