도시의 모험놀이터‘플레이파크’에 관한 고찰

신순호(Shin Soon Ho),박성현(Park Sung Hyun) 한국도시행정학회 2011 도시 행정 학보 Vol.24 No.1

The purpose of this study is to suggest a preliminary data based upon implications from the analysis of Japan’ s Play Park that how we could introduce Play Park in the urban environment. With this in mind, We have looked at the concept of Play Park, the history of Play Park, and the role of Play Park. After that, We have examined “Hanegi Play Park”, which is known for the most advanced model in Japan, based on the following analytical frameworks. First of all, We identified geographic characteristics (location, area, space, facilities, and tools), and then looked into utilization(number of users, age of users, and contents of play), operating structure(operating system and solidarity), and operating contents and method(finance, safety, program, and insurance). In order to enhance the accuracy of research, We have used the different way of research according to its characteristics such as geographic characteristics with observation and utilization, operating structure, and operating contents and method with interview. After analyses, We have found out that a few thing were shall be considered before it introduced Play Park in urban environment. First, Play Park did not require special components such as condition of site and man-made structures, therefore We suggested that we should consider trying the existing park that hardly uses or becomes obsolete on a trial basis. Second, We suggested that we need to take account of operating solidarity in order to make the best use of Play Park. In other words, it shall be an organic cooperation system that local government limits their role to provide only place and finance, while residents could take charge of Play Park operation and all other matters as a “trust”way. Last but not least, it should be discussed how to raise funds. In case of “Hanegi Play Park”, it consists of two parts with ratio of 3:1; consignment fee from local government and earnings from own business. We, however, need to discuss whether this ratio is reasonable or not. It is more desirable to raise funds through own business as much as possible rather than local government financial support.

부산시 도시공원의 입지평가에 관한 연구

이성호,박승영 부산대학교 도시문제연구소 2000 都市硏究報 Vol.10 No.-

The purpose of this study is to evaluate urban parks by location model. For the purpose of doing those, elements of location evaluation - altitude, gradient and accessibility - explored by GIS(Geographical Information System) are selected Evaluation of Location model for urban parks hardly being studied, evaluation of new model by spatial data for analysis shows possibilities in location policies of urban parks, especially, using physical and objective factors. Accessibility is examined by ratio of developed area to total area in Pusan. Altitude and gradient also are explored by each ratio of park areas. The results of evaluation of location model for urban parks in Pusan are summarized as follows; 1) A small scale park is more effective than large scale one in usability on present conditions in Pusan. 2) Most parks are located in areas which are in high altitude and severe slope ratio. Hierarchy of parks as the number of these based on parks' size is improper. Each commune called 'Gu' is very diverse and irrational in numbers and area of urban parks. Therefore, adjustment of irrational parks location is needed 3) Evaluation of this model may be different to facual evaluation because Pusan has many unmade parks. But, unmade parks must continue being constructed. Considering new location model, the problems of that are summarized as follows; 1) The method of analysis using GIS is very objective and effective in abtaining the spatial data. The following study on location and space may be very essential. 2) The problems of weight vague in relations among location elements is very important. Therefore, the more detail works should be required. 3) The model of this study is simple. For more close works, many factors - for example, park form, park management, linkage to other facilitis, etc. - must be considerated

문화유산을 활용한 테마파크형박물관에 관한 연구

박소라(Park, So La),우성호(Woo, Sung Ho) 한국실내디자인학회 2013 한국실내디자인학회논문집 Vol.22 No.6

The number of visitors to historic sites and museums in Korea has been on a rapid decrease and in order to search for creative ways to work on the problem, the study proposed a theme park-typed museum with cultural heritage applied and reviewed spatial strategies for such theme park-typed museums. Applied methods of research of this study are as follows. First, in order to understand definitions and current situations of cultural heritage use and theme park-typed museums, the study went thoroughly over all sorts of literature and reports as well as findings of advance researches on how to make a use of cultural heritage. Based on the results of the investigations, the study determined characteristics of the theme park-typed museums with cultural heritage applied which the study was proposing and the characteristics were categorized by type. Considering those characteristics and types gained in the study, the study looked for cultural heritage-based theme parks and museums in the world which were good enough to be used as research subjects in the study from the aspects of profitability and level of awareness. The study examined those theme parks and museums in the world and in the end, it found out ways to adopt the findings to the situations in Korea and discussed expecting effects as well. As to the characteristics of the theme park-typed museums with cultural heritage applied, the study divided those characteristics into mutual cooperation, location, communicability, authenticity, maintainability, education, durability, narrativity, undailiness, interactivity and leisure. The types were categorized into ride, environment direction, cartoon character and souvenir by attraction pattern. When cultural heritage is used actively, it would improve competitiveness of historic cultural sites and museums in return, making people realize the iterative structure of excavation, conservation, maintenance and use of cultural heritage. That would create many kinds of added values, re-discovering culture of the country. At the same time, it would also create a new value of culture as well. Now, it is important for us to do harder with researches on how to evolve museums and exhibition spaces. Considering that, the study is believed to make a contribution to revival of historic sites and museums in Korea but also establishment of scientific strategies.

PGA2 induces the expression of HO-1 by activating p53 in HCT116 cells

Hyein Lee,Sang-Sun Lee,Ji-Young Park,Yun-Jeong Choe,이선영,Ho-Shik Kim,H.-S. Kim 대한독성 유전단백체 학회 2017 Molecular & cellular toxicology Vol.13 No.2

Prostaglandin (PG) A2 which is a cytotoxic PG, was reported to induce the expression of heme oxygenase (HO)-1 via activation of p38MAPK to keep U2OS cells from cell cycle arrest in G2M phase. The expression of HO-1 is primarily regulated at the level of transcription. But the transcription factors that are responsible for PGA2-induced HO-1 expression were not clarified yet. Here, we report that PGA2-induced transcription of HO-1 is mediated by p53, a tumor suppressive transcription factor. In HCT116 cells, PGA2 treatment led to the phosphorylation of p53 and an increase of p21WAF1 transcription as well as the activation of HO-1 transcription. Knocking p53 down via RNA interference or inhibiting the p53’s transcriptional activity by pifithrin-α treatment led to suppression of the increase in the level of both HO-1 expression and activity of HO-1 promoter. Pretreatment of NU- 7441, a chemical inhibitor of DNA-activated protein kinase (DNA-PK), prevented both the PGA2-induced phosphorylation of p53 and an increase of HO-1 transcription. In addition, N-acetyl-l-cysteine, a scavenger of reactive oxygen species (ROS), also mimicked the effect of NU-7441 on the PGA2-induced activation of p53 and HO-1 transcription. Collectively, these results suggest that PGA2 induces the expression of HO-1 via activation of p53, which is mediated by the ROSDNA- PK pathway.

Heme oxygenase-1 induced by desoxo-narchinol-A attenuated the severity of acute pancreatitis via blockade of neutrophil infiltration

Bae, Gi-Sang,Kim, Dong-Goo,Jo, Il-Joo,Choi, Sun-Bok,Kim, Myoung-Jin,Shin, Joon Yeon,Kim, Dong-Uk,Song, Ho-Joon,Joo, Myungsoo,Park, Sung-Joo ELSEVIER 2019 INTERNATIONAL IMMUNOPHARMACOLOGY Vol.69 No.-

<P><B>Abstract</B></P> <P>Heme oxygenase-1 (HO-1) has an anti-inflammatory action in acute pancreatitis (AP). However, its mechanism of action and natural compounds/drugs to induce HO-1 in pancreas are not well understood. In this study, we investigated the regulatory mechanisms of HO-1 during AP using desoxo-narchinol-A (DN), the natural compound inducing HO-1 in the pancreas. Female C57/BL6 Mice were intraperitoneally injected with supramaximal concentrations of cerulein (50 μg/kg) hourly for 6 h to induce AP. DMSO or DN was administered intraperitoneally, then mice were sacrificed 6 h after the final cerulein injection. Administration of DN increased pancreatic HO-1 expression through activation of activating protein-1, mediated by mitogen-activated protein kinases. Furthermore, DN treatment reduced the pancreatic weight-to-body weight ratio as well as production of digestive enzymes and pro-inflammatory cytokines. Inhibition of HO-1 by tin protoporphyrin IX abolished the protective effects of DN on pancreatic damage. Additionally, DN treatment inhibited neutrophil infiltration into the pancreas via regulation of chemokine (C-X-C motif) ligand 2 (CXCL2) by HO-1. Our results suggest that DN is an effective inducer of HO-1 in the pancreas, and that HO-1 regulates neutrophil infiltration in AP via CXCL2 inhibition.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Desoxo-narchinol-A (DN) is a natural compound of HO-1 inducer in pancreas. </LI> <LI> Mechanism of DN-induced HO-1 is mediated by MAPK/Activator Protein-1/HO-1 signaling. </LI> <LI> DN-induced HO-1 blocks neutrophil infiltration into pancreas via inhibition of CXCL2. </LI> <LI> DN inhibits cerulein-induced acute pancreatitis (AP) and AP-associated lung injury. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

12M의 고해상도 360° 카메라를 사용한 주차장의 14면 주차 상태 판단 프로그램

이영지(Young-Ji Lee),이희열(Hee-Yeol Lee),고태영(Tae-Young Ko),곽동훈(Dong-Hoon Kwak),김재형(Jae-Hyung Kim),김주호(Joo-Ho Kim),오승진,이태윤(Tae-Yoon Lee),박상민(Sang-Min Park),이승호(Seung-Ho Lee) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.6

In this paper, we propose a program to identify 14 parking status in a parking lot using a high resolution 360° camera of 12M. The proposed program consists of three steps: Match with plane image, parking area detection algorithm, and discrimination of parking using learning method. Tests on a model car to evaluate the program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M showed 100% accuracy for both parking and double parking. Therefore, the effectiveness of a program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M proposed in this paper has been proved.

pH 5.5에서 유기산 완충용액의 포화도 변화에 따른 법랑질의 재광화 양상

박진성,박성호,박정원,이찬영 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.2

The purpose of this study is to observe and compare the remineralization tendencies of artificial enamel caries lesion by remineralization solutions of different degree of saturations at pH 5.5, using a polarizing microscope and computer programs (Photoshop, Image pro plus, Scion Image, Excel). For this study, 48 sound permanent teeth with no signs of demineralization, cracks, or dental restorations were used. The specimens were immersed in lactic acid demineralization solution for 2 days in order to produce artificial dental caries that consist of surface and subsurface lesions. Each of 9 or 10 specimens was immersed in pH 5.5 lactic acid buffering remineralization solution of four different degrees of saturation (0.507, 0.394, 0.301, and 0.251) for 12 days. After the demineralization and remineralization, images were taken by a polarizing microscope (×100). The results were obtained by observing images of the specimens, and using computer programs, the density of caries lesions were estimated. While the group with the lowest degree of saturation (0.251) showed total remineralization feature from the surface to the subsurface of the lesion, the group with the highest degree of saturation (0.507) showed demineralization mainly on the surface of the lesion at the constant organic acid concentration 0.01 M and pH 5.5. 본 연구에서는 lactic acid를 이용하여 인공 탈회용액을 제조하여 우식이 없는 치아로 시편을 만들고 법랑질 부위에 인공 우식 병소를 생성 시키고 유기산 농도 0.01 M, pH 5.5로 고정한 상태에서 유기산 완충용액의 포화도를 달리하여(0.507, 0.394, 0.301, 0.251) 재광화를 시키고 편광 현미경하에서 관찰 및 디지털 카메라로 촬영하였다. 이를 통해 얻은 상에서 탈회 깊이의 변화, 우식 표면층 폭의 변화, 무기질의 양적 변화를 컴퓨터 프로그램을 이용하여 비교, 통계 분석하여 다음 결과를 얻었다. 1. 재광화 전에 비하여 재광화 후 모든 군에서 10-30% 재광화 양이 증가 하였다. 2. 재광화 후 4군에서는 우식 표면층과 심부 모두에서 재광화가 일어나는 양상이 나타난 반면 1군에서는 심부 보다 우식 표면층 부위의 재광화가 더 일어난 양상이 관찰되었다. 3. 재광화 후 시편의 탈회된 깊이의 변화는 탈회시킨 후와 비교할 때 모든 군에서 유의할만한 변화는 없었으며 군간의 통계적 유의차도 없었다. 결론적으로, 유기산 0.01 M, pH 5.5로 고정한 상태에서 포화도가 가장 낮았던 군(0.251)에서는 우식 표면층에서 심부까지 재광화가 일어난 반면, 포화도가 가장 높았던 군(0.507)에서는 우식 표면층에서 재광화가 주로 일어났다.

차량 재도색용 청색 페인트의 분석

박성우,손성건,박하선,박성지,정영호,홍성욱,박종신 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

Effect of Mn and C on Age Hardening of Fe–Mn–Al–C Lightweight Steels

Sung‑Won Park,Jun Young Park,Kyong Mox Cho,Jae Hoon Jang,Seong‑Jun Park,Joonoh Moon,Tae‑Ho Lee,Jong‑Ho Shin 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.3

The effects of Mn and C content on the age hardening of Fe–Mn–Al–C lightweight steels, which have austenitic or duplex(austenite and ferrite) microstructures, were investigated. An increase in Mn content induced a delay of the age hardeningthat is caused by the formation of intra-granular κ-carbides. In order to interpret the effect of Mn content, first-principlescalculations were conducted using the supercells of Fe24Al8C8,Fe24Al8C7,Fe24(Al7Mn)C8, and Fe24(Al7Mn)C7. The calculationsshowed that an increase in Mn content could be the source of the delay of the intra-granular κ-carbide formation bysuppressing C atom’ occupation of the vacancy at the body-centered site of L12. An increase in C content accelerated theformation of intra-granular κ-carbides, which induced the intense age hardening, and coarse inter-granular κ-carbides, whichresulted in significant decrease in impact absorbed energy due to inter-granular fracture.

건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.