흰쥐의 발치와에 이식한 단계별 치아싹의 발육 과정

정희훈,정한성,김성오,최형준,이제호,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

The purpose of this study is to evaluate at which stage of tooth germ would develop into normal calcification and hence to increase the success rate of transplantation. Therefore, tooth germs on the 15th, 17th embryonic day and the 3rd day of birth were separated for allotransplantation into maxilla of adult rat of 11 weeks. Calcification processes were analyzed radiographically and histopathologically at 4 weeks and 8 weeks after allotransplantation. The results are as follows: 1. Allotransplanted tooth germ at 4 weeks and 8 weeks showed delayed calcification compared to that of normal odontogenesis. 2. At 4 weeks, abnormal calcified tissue, such as odontoma and ankylosis of osteodentin with surrounding alveolar bone were observed. 3. At 8 weeks, allotransplanted tooth germs of the 15th and 17th embryonic day showed calcification and osteodentin surrounded by periodontal ligament. 4. At 8 weeks, allotransplanted tooth germs of the 3rd day of birth showed calcification composed of cementum and osteodentin. In this study, we observed small sized and amorphous calcified tissue from allotropic allotransplantation of tooth germs. Since these calcified tissue were underdeveloped and shaped irregularly, for calcification into normal tooth form, further study needs consideration about the reduction of surgical trauma, developmental stage of transplanted tooth germ, blood supply from recipient site, fixation method in transplanted site and period of transplantation. 외상이나 치주 질환,유전적 결함 등에 의하여 치아가 상실되었을 경우,보철 수복이나 임플란트로 치료하고 있다. 그러나 보철 수복이나 임플란트는 자연치가 아닌 인공치를 이용한 치료로서 기능성과 섬미성 등에서 자연치에 비하여 한계 가 있으므로 자연치를 이용한 이식 방법에 관심이 증가하고 있으며 치아 이식의 성공률을 높이기 위한 이식 치아의 발육과 성장에 대한 연구가 진행 중이다. 이 연구는 세 가지 단계의 치아싹을 발치와에 동종 이식하고 치아싹이 발육하여 석회화가 이루어지는지 평가하기 위하여 임선 15일과 17일,출생 후 3일 된 흰쥐의 치아싹을 분리하여 11주 된 흰쥐의 발치와에 이식하고 4주와 8주 후 방사 선학적 그리고 병리조직학적으로 석회화 과정을 관찰하여 다음과 같은 결과를 얻었다. 1. 발치와에 이식된 임신 15일과 17일,출생 후 3일 된 치아싹에서 4주와 8주 후 석회화된 조직이 형성되었다. 2. 임신 15일과 17일,출생 후 3일 된 치아싹을 발치와에 이식하고 4주 후 치아종 같은 비정상적인 석회화 조직과 인접 치조골과 유착된 골양상아질이 관찰되었다. 3. 임신 15일과 17일 된 치아싹을 발치와에 이식하고 8주 후 골양상아질이 보였으며 치주인대로 둘러싸인 것도 관찰되었다. 4. 출생 후 3일 된 치아싹을 발치와에 이식하고 8주 후 골양상아질과 백악질이 형성되었다. 이 연구는 치아싹을 흰쥐의 발치와에 이식한 후 치아싹의 발육을 관찰한 것으로 이식 조직에서 크기가 작고 무정형의 석회화 조직이 형성되었다. 정상적인 치아보다 형태가 불규칙하고 발육이 늦었으므로 이식된 치아싹이 정상적인 치아 형태로 석회화되도록 하기 위해서는 이식 조직의 발육 정도와 이식 조직을 절제할 때 외과적 손상의 감소,치아싹으로의 풍부한 혈류 공급,이삭 기간,이식 조직의 고정을 고려하여 더 많은 연구가 필요할 것으로 생각된다.

아이 트래커를 활용한 인터넷 광고의 선택적 주의 요소 효과 연구

김지호,김재휘,박하철,이장한 한국방송광고공사 2006 광고연구 Vol.0 No.72

본 연구에서는 인터넷 광고에 대한 소비자들의 시각적 주의를 검증하기 위해 아이 트래커로 실험을 진행하였다. 인터넷 포털 사이트에서 실제로 집행된 광고를 실험 자극으로 선정하였으며, 광고 속성들과 소비자들의 인터넷 사용 목적이 시각적 주의에 영향을 주는지 검증하고자 하였다. 본 연구에서는 자극유형(텍스트/그림), 부분적 겹침(있음/없음), 상대적 높이(상/중/하), 대조(강/중/약), 광고자극 내 대조(강/중/약), 광고 위치(좌/우)의 자극 속성들과 과제 조건(유/무)의 주효과 및 상호작용을 검증하고자 하였다. 연구결과 자극 속성인 광고 제시 유형, 대조, 광고 자극 내 대조와 과제 탐색은 각각의 주효과와 상호작용 효과가 모두 유의미하였으나, 부분적 겹침, 상대적 높이는 상호작용만 유의미하였다. 한편, 뇌의 반구 처리 유형에 의한 그림/텍스트 광고의 좌우 위치 효과의 결과는 가설과 일치되지 않는 결과를 나타내었다. The purpose of this study was to examine the attention to the internet ads of consumers. Unlike the prior studies, this study was collected the eye fixation data of participants through the eye tracker apparatus. The results showed that the participants attended to the ads as a result of activating top-down processing, caused by their goal of using internet and learned visual searching route. In addition, each type of ad(pictorial and text) was gathered different visual attention as a result of bottom-up process and was interacted with goal of using internet. And stimuli attributes in the ads, like partially occlusion and contrast led to participants’ attention to the ads differently. But relative height in the visual field had no significance and locations of ads didn’t have correspondent results. Finally, limitations of this paper and future research directions were discussed.

비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

Is Bone Grafting Necessary in Opening Wedge High Tibial Osteotomy? A Meta-Analysis of Radiological Outcomes

( Jae Hwi Han ),( Hyun Jung Kim ),( Jae Gwang Song ),( Jae Hyuk Yang ),( Nikhl N Bhandare ),( Aldrich Raymund Fernandez ),( Hyung Jun Park ),( Kyung Wook Nha ) 대한슬관절학회 2015 대한슬관절학회지 Vol.27 No.4

Purpose: Bone grafting in opening wedge high tibial osteotomy (OWHTO) is still controversial. The purpose of this study is to compare the radiological outcomes of OWHTO with bone graft (autogenous, allogenous, and synthetic bone graft) and those without bone graft. Materials and Methods: PubMed, MEDLINE, EMBASE and Cochrane Register of Studies databases were searched using specific inclusion and exclusion criteria for radiological studies involving OWHTO with bone graft and without bone graft groups. All reported delayed union, nonunion and correction loss were analyzed. Data were searched from the time period of January 2000 through July 2014. In addition, a modified Coleman methodology score (CMS) system was used to assess the methodological quality of the included studies. Results: Twenty-five studies with a mean CMS value of 77 (range, 61 to 85 score) were included. In total, 1,841 patients underwent OWHTO using 4 different procedures for bone graft: autobone graft (n=352), allobone graft (n=547), synthetic bone graft (n=541) and no bone graft (n=401). There was a similar tendency for delayed union, nonunion and correction loss rate among the osteotomy space filling methods. Conclusions: The meta-analysis showed there was a similar tendency for radiological union and correction maintenance among patients undergoing OWHTO regardless of the type of bone in all of the studies. However, the currently available evidence is not sufficient to strongly support the superiority of OWHTO with bone graft to OWHTO without bone graft.

Case Report : Spontaneous Healing of a Displaced Bucket-Handle Tear of the Lateral Meniscus in a Child

( Jae Hwi Han ),( Jae Gwang Song ),( Jae Ho Kwon ),( Kyung Woon Kang ),( Daviesh Shah ),( Kyung Wook Nha ) 대한슬관절학회 2015 대한슬관절학회지 Vol.27 No.1

Bucket-handle tears less frequently occur in the lateral meniscus than in the medial meniscus. An 11-year-old male patient complained of painful swelling and locking due to a displaced bucket-handle tear of the lateral meniscus. We recommended an arthroscopic surgery; however, the patient left the hospital without surgical treatment. Six weeks afterwards, he returned without any complain of pain and he regained full range of motion. The final follow-up magnetic resonance imaging showed reduction of the torn meniscal fragment without any signal changes suggestive of a meniscal tear. We report a rare case of an isolated displaced bucket-handle tear of the lateral meniscus in an 11-year-old patient that healed spontaneously without surgical intervention.

비위관과 유도철사를 사용한 전 척추에 걸친 전방 경막외 농양의 최소 침습 수술적 치료

한재휘(Jae Hwi Han),신재욱(Jae Uk Shin),최성(Sung Choi) 대한정형외과학회 2023 대한정형외과학회지 Vol.58 No.5

Themida의 API 난독화 분석과 복구방안 연구

이재휘(Jae-hwi Lee),한재혁(Jaehyeok Han),이민욱(Min-wook Lee),최재문(Jae-mun Choi),백현우(Hyunwoo Baek),이상진(Sang-jin Lee) 한국정보보호학회 2017 정보보호학회논문지 Vol.27 No.1

프로텍터란 프로그램의 핵심 아이디어를 보호하기 위해 실행파일을 압축하고 난독화를 적용하는 프로그램이다. 그리고 최근 악성코드가 자신의 악성행위를 분석하기 어렵게 만들기 위해 프로텍터를 적용하고 있다. 프로텍터가 적용된 실행파일을 정밀분석하기 위해서는 프로텍터를 해제하는 언패킹 작업이 필요하다. 기존의 연구에서는 OEP를 찾아 언패킹을 하는 것에 주력하였지만, 분석방해가 목적인 프로텍터의 경우 실행압축 해제가 완료된 이후의 실행에 분석방해 기능들이 남아있게 되어 여전히 분석에 어려움이 있다. 본 논문에서는 분석방해가 목적인 Themida 프로텍터가 사용하는 분석방해 기술을 분석하고 그에 대한 대응방안을 제안한다. A protector is a software for protecting core technologies by using compression and encryption. Nowadays malwares use the protector to conceal the malicious code from the analysis. For detailed analysis of packed program, unpacking the protector is a necessary procedure. Lately, most studies focused on finding OEP to unpack the program. However, in this case, it would be difficult to analyze the program because of the limits to remove protecting functions by finding OEP. In this paper, we studied about the protecting functions in the Themida and propose an unpacking technique for it.

개방형 및 폐쇄형 근위경골절골술의 최신 지견과 장기 추시 결과

한재휘(Jae Hwi Han),나경욱(Kyung Wook Nha),이성산(Sung-Sahn Lee) 대한정형외과학회 2023 대한정형외과학회지 Vol.58 No.3

A Study on the Development of High Slip Resistance Rubber for Ice

( Han Dong-hun ),( Ju Jae-hwi ),( Lee Dan-bi ),( Kim Young-min ) 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.1