일부 충남지역 여대생의 혈청 마그네슘(Mg), 칼슘(Ca), 칼슘/마그네슘(Ca/Mg)비율과 혈청지질과의 상관관계 연구

김애정 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.4

Magnesium(Mg) plays an important role in lipid metabolism and Mg deficiency, but Ca sufficiency increases serum cholesterol and triglyceride. The relationships of serum Mg, Ca, Ca/Mg ratio with lipids was examined in 79 female college students in Choong-Nam area. Subjects were divided into underweight, normal and overweight groups according to their BMI. The average age, body weight, height and BMI were 21.9yr, 55.9㎏, 158.5㎝ and 22.62㎏ /㎡ respectively. Height was not different between groups. Serum cholesterol and LDL-cholesterol concentrations were significantly lower in the underweight group than other groups. BMI had positive correlations with LDL-cholesterol, atherogenic index(AI) and LDL-cholesterol/HDL-cholesterol ratio(LPH), and negative correlations with HDL-cholesterol/total cholesterol ratio. Serum minerals(serum Mg, Ca, Ca/Mg ratio) and serum lipid concentrations were not significantly different between groups. However, there was a tendency of increasing serum Mg level with increasing serum HDL-cholestrol, HDL-cholesterol/total cholesterol ratio and decreasing serum LDL-cholesterol LPH, total cholesterol/HDL-cholesterol ratio(TPH) and AI. And there was a tendency of increasing serum Ca level with increasing serum HDL-cholesterol/total cholesterol ratio and decreasing serum triglyceride, LDL-cholesterol, LPH, TPH and AI. And there was a tendency of increasing serum Ca/Mg ratio level with decreasing triglyceride, serum LDL-cholesterol and TPH. This study was limited within serum levels of minerals(serum Mg, Ca and Ca/Mg ratio), serum lipids concerned with CHD, therefore I hope there will be wider efforts to consider about the dietary levels of minerals for presentation of the connection between dietary Mg, Ca and serum lipids.

항고혈압제 사용중 혈중지질의 변화

김상욱(Sang Wook Kim),송태호(Tae Ho Song),김철우(Cheul Woo Kim),권기익(Ki Ik Kwon),유언호(Un Ho Ryoo) 대한내과학회 1994 대한내과학회지 Vol.47 No.1

Background: Hypertension is a major risk factor for atherosclerotic vascular disease. Many antihypertensive drugs are known to alter lipoprotein metabolism and this may override the benefit of blood pressure reduction. The purpose of this study is to evaluate the effects of the antihypertensive therapy in serum lipid. Method: The clinical study was done on 200 patients with hypertension who treated with esidrex, beta-blocker, or esidrex plus beta-blocker as an antihypertensive medication. The patients were divided into three groups according to the antihypertensive regimens. The serum lipid values were checked before and during antihypertensive therapy. Average follow up period of serum lipid was about 2 years. Results : 1) The serum lipid values before antihypertensive therapy were triglyceride 177±125 mg/dl, HDL-cholesterol 42±12 mg/dl, total cholesterol 230±50 mg/dl, and 1 year after antihypertensive therapy, triglyceride 233±134 mg/dl, HDL-cholesterol 43±22 mg/dl, total cholesterol 235±47 mg/dl, and 2 year after antihypertensive therapy, triglyceride 243±172 mg/dl, HDL-cholesterol 45±11 mg/dl, total cholesterol 233±40 mg/dl. The serum triglyceride and total cholesterol were increased significantly after antihypertensive therapy. 2) In 30 patients with esidrex therapy, the serum total cholesterol was elevated than the pretreatment value (p<0.05); pretreatment value 228±59 mg/dl, 6 months 233±53 mg/dl, 1 year 239±53 mg/dl, 2 year 238±39 mg/ dl. 3) In 81 patients with beta-blocker therapy, the serum triglyceride was elevated than the pretreatment value (p<0.05); pretreatment value 164±67 mg/dl, 6 months 183±72 mg/dl, 1 year 245±75 mg/dl, 2 year 205±84 mg/ dl. 4) In 89 patients with esidrex plus beta-blocker therapy, the serum total cholesterol was elevated than pretreatment value (p<0.05); pretreatment value 210±45 mg/dl, 6 month 264±50 mg/dl, l year 237±53 mg/dl, 2 year 225±48 mg/di, and triglyceride was also elevated; pretreatment value 163±87 mg/dl, 6 months 195±76 mg/dl, 1 year 208±80 mg/dl, 2 year 211±85 mg/ dl, But the serum HDL cholesterol was not elevated significantly. Conclusion : The esidrex therapy was associated with the elevation of serum total cholesterol and beta- blocker therapy was associated with the elevation of serum triglyceride. The serum total cholesterol and triglyceride were increased during esidrex plus beta-blocker therapy.

저분자화알긴산이 콜레스테롤식이 흰쥐의 혈청과 간장지질의 콜레스테롤 수준 및 지방산 조성에 미치는 영향

이동수,남택정,변재형,LEE Dong-Soo,NAM Taek-Jeong,PYEUN Jae-Hyeung 한국수산과학회 1998 한국수산과학회지 Vol.31 No.3

미역과 큰다시마에서 추출한 수용성 알긴산 및 산$\cdot$알칼리가용성 알긴산과 그 염산부분가수분해에 의하여 얻어진 저분자화 알긴산 (저분자화 범위 : 미역 약 4,000 kDa$\to$약 38kDa; 큰다시마 약 1.283kDa$\to$약 341 kDa과 약 45kDa)을 함유한 실험사료를 횐쥐 (SD계, 4주령)에 4주간 급이했을 때의 혈청 및 간장지질 콜레스테롤 수준 및 지방산 조성에 미치는 영향을 실험$\cdot$검토하였다. 알긴산의 급이는 식이효율이 $0.37\~0.44$로서 기초식이군에 비하여 $0.03\~0.05$ 정도 낮은 값을 보였고, 콜레스테롤 급이에 의한 간의 중량 증가도 유의적으로 억제하였다. 수용성 알긴산은 산$\cdot$알칼리가용성 알긴산에 비하여 혈청 및 간장지질 중의 총콜레스테롤, 유리콜레스테롤, LDL-콜레스테롤, triglyceride및 인지질에 대하여 현저한저감효과를 보였다. 그리고 각각의 효과는 저분자화에 의하여 현저히 증대되었다(저분자화에 의한 저감효과 수용성 알긴산 - 혈청지질: 총콜레스테롤 $59\%$, 유리콜레스테롤 $65\%$, LDL-콜레스테롤 $96\%$, triglyceride $50\%$, 인지질 $36\%$, 간장지질: 총콜레스테롤 $42\%$, 유리콜레스테롤 $62\%$, LDL-콜레스테롤 $44\%$, triglyceride $33\%$, 인지질 $44\%$ 산$\cdot$알칼리가용성 알긴산 - 혈청지질: 총콜레스테롤 $52\%$, 유리콜레스테롤 $97\%$, LDL-콜레스테롤 $78\%$, triglyceride $32\%$, 인지질 $64\%$, 간장지질. 총콜레스테롤 $11\%$, 유리콜레스테롤 $12\%$, LDL-콜레스테롤 $10\%$, triglyceride $27\%$, 인지질 $21\%$) 저분자화 알긴산의 급이가 혈청 및 간장지질 구성지방산의 조성에 미치는 효과는 콜레스테롤 급이군에 비하여 polyene산의 함유비율을 혈청지질에 있어서는 약 $44\%$이상, 그리고, 간장지질에 있어서는 약 $70\%$ 이상으로 각각 증가시켰다. 이상의 결과에 비추어 저분자화 알긴산의 급이는 실험동물의 혈청 및 간장지질 조성을 생리적으로 개선하는데 그 효과가 현저함을 뒷받침하였다. The effect of low molecular alginates feeding on the cholesterol levels and fatty acid compositions of rat serum and liver lipid were investigated. After one week basal diet feeding, four week old Sprague-Dawley male rats were fed with water soluble and acid $\cdot$alkali soluble alginate extracted from sea mustard (Undaria pinnatifida) and giant kelp (Macrocystis pyrifera), and their low molecular alginates prepared by the HCl partial hydrolysis. The feeding efficiency of the alginate fed group was ranged in 0.37$\~$0.44, which was 0.03$\~$0.05 lower than that of the basal diet group. Also, there was much less increase of liver weight in the alginate fed group. The water soluble alginate showed more significant effect in reducing the total cholesterol, free cholesterol, LDL-cholesterol, triglyceride and phospholipid of serum and liver lipid than the acid$\cdot$alkali soluble alginate. The effect was much better with low molecular alginate (reducing effect by the low-molecularization : Water soluble alginate - serum lipid; total cholesterol $59\%$, free cholesterol $65\%$, LDL-cholesterol $96\%$, triglyceride $50\%$, and phospholipid $36\%$. liver lipid: total cholesterol $4\%$, free cholesterol $62\%$, LDL-cholesterol $44\%$, triglyceride $33\%$, and phospholipid $44\%$. acid$\cdot$alkali soluble alginate - serum lipid; total cholesterol $52\%$: free cholesterol $97\%$, LDL-cholesterol $78\%$ triglyceride $32\%$, and phospholipid $64\%$. liver lipid; total cholesterol $11\%$, free cholesterol $12\%$, LDL-cholesterol $10\%$, triglyceride $27\%$, and phospholipid $21\%$). The effect of low molecular alginate feeding on the fatty acid composition of serum and liver lipid reflects the remarkable increase of polyenoic acid, over $44\%$ in serum lipid and about $70\%$ in liver lipid, comparing to the cholesterol fed group. The overall results indicated that feeding of low molecular alginates improves physiological function of rats by changing the serum and liver lipid composition.

비지가 고지방 식이 흰쥐의 혈청 지질성분에 미치는 영향

김한수,김군자,김용균 密陽産業大學校 農業技術開發硏究所 1999 農業技術開發硏究所報 Vol.3 No.2

비지가 혈청중 지질대사에 미치는 영향을 검토하기 위해 Sprague-Dawley계 숫 흰쥐에 lard와 cholesterol, 비지 및 비지에 함유된 섬유소 비율로 cellolose를 첨가한 식이를 5주간 급여한 후 혈청중의 지질성분 함량을 검토한 결과, 고지방 식이군은 체중과 식이섭취량이 감소하였으나 비지와 cellulose의 급여에 의하여 식이효율이 증가하였다. 간장, 신장, 심장, 비장의 체중은 증가량에 따라 증가하는 경향을 보였으며, 혈청중 AST, ALT 활성은 고지방 식이군(HF군)에 비해 비지를 급여한 군에서는 유의한 감소를 나타내었으며 cellulose 급여군에서는 유의성이 없었다. 혈청중 total lipid, cholesterol 및 phospholipid의 함량은 고지방 식이군(HF군)에 대조군에 비하여 증가하였고, 비지 30% 급여군에서는 감소하였으나 여타 실험군에서는 유의성이 없었다. 혈청중 HDL-cholesterol 함량은 고지방 식이에 비해 비지 30% 급여군에서 증가하였으나 cellulose 급여균에서는 감소하였다. 혈청중 VLDL·LDL-cholesterol함량은 대조군에 비해 고지방 식이군(HF군)은 증가하였으며 비지를 급여한 급여수준을 증가함에 따라 감소하였다. 혈청중 동맥경화지수는 대조군에 비해 고지방 식이군이 증가하였다. 고지방 식이군에 비해 비지를 급여한 군에서는 감소를 보인 반면에 cellulose급여군에서는 차이를 볼 수 없었다. 혈청중의 tirglyceride 의 함량은 대조군에 비해 고지방 식이군은 유의한 증가를 보였고 비지와 cellolose를 급여한 군에서는 유의한 차이가 없었다. 이상의 결과, 비지가 혈청중의 지질성분을 저하시켜 고지혈증 개선작용을 하므로 대사성질환의 예방에 도움을 끼칠 것으로 생각된다. This study has been undertaken to investigate the effect of supplementated soybean curd refuse(dry form) and cellulose to rat food on the lipid composition and the activities of AST, ALT in high fat rat of serum. Forty-eight males of Sprague-Dawley strains weighed about 100~110g were divided into 8 groups, with each group receving a different diet for 5 week; i.e. control diet, high fat diet plus 10% of soybean curd refuse, high fat diet plus 20% of soybean curd refuse, high fat diet plus 30% of soybean curd refuse, high fat diet plus 3.6% of cellulose, high fat diet plus 7.2% of cellulose and high fat diet plus 10.8% of cellulose. Total lipid, total cholesterol, phospholipid, triglyceride, HDH-cholesterol, aspartate aminortansferase and alanine aminotransferase were determined in serum. Rats given feed containing high fat showed significant decrease in net weight gain and feed intake, but supplement of soybean curd refuse and cellulose to the rat feed caused an increase in feed efficiency ratio. Each of the liver, kidney, heart and spleen weight of experimental groups was tended to be increased with increasing net weight gain of them. Activity of AST, ALT in serum and contents of soybean curd refuse added groups were significantly decreased as compared with high fat fed group. The contents of total lipid, total cholesterol and phospholipid in serum were significantly increased in high fat fed group but 30% of soybean curd refuse fed group decreased as compared with control group. But there was no change in contents of them in serum of other groups. The contents of HDL-cholesterol in serum were significantly increased in soybean curd refuse added groups but decreased in cellulose containing groups compared to high fat fed group. The contents of VLDL·LDL-cholesterol in serum were significantly increased in high fat fed group compared with control group. Contents of the soybean curd refuse added groups were tended to be significantly with increasing dietary soybean curd refuse. The atheroscleterotic index, content ratio of VLDL·LDL-cholesterol and HDL-cholesterol of serum were significantly increased in high fat fed group compared with control group, but that was lower in soybean curd refuse added groups and no change in cellulose containing groups compared with high fat fed group. Contents of tirglyceride in serum of the high fat fed group were significantly increased as compared with the control group, but soybean curd refuse and cellulose containing groups were not significantly different compared as the high fat fed group. From the above experimental results it seems that soybean curd refuse would improve the serum lipid component and prevent the metabolic disease by improving hyperlipemia.

생우유 과량섭취와 관련된 영유아의 혈청 무기질과 미량원소 함량 및 지질조성

안홍석,배현숙,박성혜,정은정,오경환 대한지역사회영양학회 1997 대한지역사회영양학회지 Vol.2 No.4

This study was conducted to determine the effect of large amounts of whole cow's milk intake on serum levels of minerals and lipids. Subjects were normal infants who were brought to the pediatric hospital for vaccination at the age of 7-26 months after birth, living in Eumsung-Choongbuk area. The serum concentrations of the imnerals(calcium, phosphorus, magnesium, iron, zinc and copper), lipids and fatty acids composition were analyzed in 38 infants which consumed large amount of whole cow's milk(over 700ml/day). The results obtained are summarized as follows : 1) The mean levels of calcium, phosphorus and magnesium in the serum of the total subjects were 7.56$\pm$0.51mg/dl, 11.12$\pm$0.72mg/dl and 1.62$\pm$0.13mg/dl respectively. The serum concentrations of iron, zinc and copper in total subjects averaged 72.42$\pm$1.62$\mu\textrm{g}$/dl, 76.29$\pm$3. 62$\mu\textrm{g}$/dl and 86.44$\pm$2.98$\mu\textrm{g}$/dl respectively. 2) The mean serum concentrations of triglyceride, total cholesterol, HDL and LDL in the total number of subjects were 96.84$\pm$9.22mg/dl, 133.45$\pm$6.30mg/dl, 32.79$\pm$1.77mg/dl and 81.29$\pm$4.81mg/dl respectively. 3) The average percentages of SFA, MUFA and PUFA inth total serum fatty acids were 38.98$\pm$2.42$\%$, 25.82$\pm$0.98$\%$ and 37.30$\pm$1.09$\%$ respectively and the mean$w6/w3$fatty acids ratio was 13.48. In general, the levels of serum minerals and $\omega$3 fatty acid composition in the subjects of this study, who were whole cow's milk fed infants were lower than those reported in breast milk or formula fed infants. Therefore, the intake of large amount of whole cow's milk in the weani ng period should be controlled and adequate for the infant's nutritional status. (Korean J Community 2(4) : 477-485, 1997)

나환자의 혈청 과산화 지질

노용지,송준영,박의수 啓明大學校 醫科大學 1992 계명의대학술지 Vol.11 No.1

Lipid peroxide is metabolic products of unsaturated fatty acid which functions, in vivo, are detoxification, drug metabolism, production of prostaglandins and microcidal action. If lipid peroxide increase in serum which causes variable metabolic disorders by impairement of organ cell membranes. But several enzymatic systems prevent high accumulations of lipid peroxide in serum. In this study, we have examined serum lipid peroxide conentration by using Yagi's method in 31 lepromatous leprosy patients and 11 tuberculoid leprosy patients. As normal controls, 22 healthy persons have been selected. As the results, Values of lipid perxide in leprosy patients superior to normal controls statistically(The values are significant only in lepromatous leprosy, not significant in tuberculoid leprosy patients.) We also found that sex, age, duration of disease had not affected the lipid peroxide levels. These results suggested that the type and severity of leprosy may be related the level of lipid peroxide. Now we present a paper, serum lipid peroxide in leprosy patients, with references.

일부 여대생의 영양소 섭취상태, 빈혈 지표 및 혈청 지질간의 상관성에 관한 연구

김미정,노숙령 동아시아식생활학회 1999 동아시아식생활학회지 Vol.9 No.3

This study was conducted to evaluate nutrient intake, indices of anemia, serum lipids, and their correlations in 40 Korean female college students aged 21 to 25 years, Fasting blood samples were collected in October, 1997. Nutrient intake was investigated by 24-hour recall method for three days, Anthropometric measurements, blood pressure, iron status and serum lipids of the subjects were determined. The mean values for age, height, weight, BMI and blood pressure of the subjects were 22.1 years, 160,6cm, 54.4kg and 109.1/66.9mmHg, respectively. According to the body composition analysis, total body water, % body fat, lean body mass and WHR were 26.7L, 29.5%. 36.5㎏ and 0.8, respectively. Average daily intake of energy was 1,858.4kcal. Protein, phosphorus, vitamin B₁, vitamin B₂, niacin and vitamin C intakes were higher than the Korean recommended dietary allowence(RDA), whereas calcium, iron, vitamin A intakes were lower than that, Hemoglobin(Hb), hematocrit(Hct), serum iron(SI) and total iron binding capacity(TIBC) were measured and transferrin saturation(TS%) was calculated from serum. The mean values for Hb, Hct, SI, TIBC and TS were 13.6㎍/dl, 41.6%, 97.8㎍/dl, 319.6㎍/dl and 31.9%, respectively. The prevalence rates of iron deficiency assessed by Hb and Hct were found to be 10% and 2.5%, respectively. However, when assessed with TIBC, the prevalence rate of iron deficiency was increased to 32.5%. The mean values for serum triglyceride(TG), total cholesterol(TC), HDL-Chol, LDL-Chol concentrations and atherogenic index(AI) were 154.7mg/dl, 80.0mg/dl, 47.1mg/dl, 91,3mg/dl and 2.6, respectively. Correlations among indices of anemia, there were positive correlations between Hb and Hct, between SI and TS: negative correlations between TIBC and TS or SI. Correlations among serum lipids, there were positive correlations between TC and TG or LDL-cholesterol. Energy intakes were correlated positively with TIBC(p<0.05), and vitamin C intakes negatively correlated with Hb(p<0,05). And vitamin A intakes were negatively correlated with TG(p<0.01), TC(p<0.05) and LDL-Choi(p<0.01). Hb negatively correlated with TG(p<0.05). Body weights(p< 0.05), lean body mass(p<0.05) and total body water(p<0.01) werenegatively correlated with Hb. BMI and WHR correlated with TG and TC(p<0.01). These results indicated that subjects with higher energy intake and overweight had a tendency to have iron deficiency. Increases in BMI and WHR were related to increases in serum lipids levels and decreases in TIBC. The results also showed that serum lipids were decreased when vitamin A and iron intakes were sufficient.

Effect of Kale Juice on Serum Lipid Levels & Phospholipid Fatty Acid Composition in Hypercholesterolemic Men

Eun Jung Chung(정은정),Eugene Shim(심유진),Soo Yeon Kim(김수연) 한국생명과학회 2012 생명과학회지 Vol.22 No.11

고콜레스테롤혈증(총 콜레스테롤 농도 200 mg/dl 이상)인 성인 남자를 대상으로 12주간 케일녹즙 중재실험을 실시하여 실험 전과 후의 혈청 지질농도와 혈청 인지질 지방산 조성의 변화를 살펴보았다. 혈청 총 콜레스테롤 및 중성지방 농도는 녹즙 섭취 전과 후에 유의한 차이를 보이지 않았으나 HDL-콜레스테롤 농도는 녹즙 섭취 후 유의하게 증가하였고, LDL-콜레스테롤은 유의하게 감소하였으며 atherogenic index 역시 녹즙 섭취 후 유의하게 감소하였다. 대상자들은 녹즙 섭취 전ㆍ후로 BMI, 허리둘레, 혈압 등의 신체계측치와 흡연, 음주 등의 생활습관 및 영양소 섭취패턴에 유의한 변화 없이 12주 중재실험기간 동안 평상시 생활패턴을 유지하였다. 실험에 사용된 녹즙에 섬유소가 거의 함유되어있지 않으므로 혈청지질 개선효과는 녹즙에 풍부한 항산화 영양소에 의한 효과로 사료된다. 녹즙섭취 후에 유의한 변화를 보인 혈청 인지질 지방산 조성 중에서 12:0, 14:0, 18:1ω9, 18:3ω6 조성 및 총 단일불포화지방산 조성은 증가하고 22:4ω6 조성은 감소하였다. 특히 올레산(18:1ω9) 조성은 55∼58% 증가하였는데 다중불포화지방산 못지않게 혈중 콜레스테롤 농도를 감소시켜주며, 다중불포화지방산보다 LDL의 산화를 감소시켜 동맥경화증이나 관상심장질환의 위험을 줄여주는 지방산으로 알려져 있다. 12주간의 녹즙섭취는 혈청 인지질의 지방산 조성은 크게 변화시키지 않지만 궁극적으로 지방조직의 지방산 조성에 변화를 초래하고 이로 인해 고콜레스테롤 환자의 혈중 지질농도를 개선시켜줄 것으로 사료된다. The aim of this study was to evaluate the effect of kale (Brassica oleracea acephala) juice supplementation on serum lipid levels and phospholipid (PL) fatty acid compositions in hypercholesterolemic men. Thirty-two men with hypercholesterolemia (>200 mg/dl) were recruited among the faculty and staff at Y University after annual health examinations. The subjects consumed 150 ml of kale juice per day for a 12-week intervention period. Dietary and anthropometric assessments were performed before and after supplementation, respectively, to ensure that the subjects maintained their usual diet and lifestyle throughout the intervention. Serum concentrations of HDL-cholesterol and the ratio of HDL-cholesterol to LDL-cholesterol were significantly increased (p<0.001) after intervention. Serum LDL-cholesterol concentration and atherogenic index were significantly reduced (p<0.001). Levels of 12:0, 14:0, 18:1ω9, 18:3ω6, and sum of monounsaturated fatty acids (MUFA) in serum pholspholipid (PL) were significantly increased, while 22:4ω6 level was significantly reduced (p<0.05). It can be speculated that kale juice, containing large amounts of antioxidant nutrients, contributes to changes of serum-PL-fatty acid compositions and the improvements of serum lipid profiles. This study demonstrates the supplementation of regular meals with kale juice may favorably affect serum lipid profiles and serum-PL fatty acid compositions and, hence, could lower the risks of coronary artery disease in men with hypercholesterolemia.

The Correlatin of Dietary Cr, Cu and Zn Levels with Serum Lipid Healthy College Women Living in Choongnam Area

Kim, Ae-Jung,Yuh, Chung-Suk,Kim, Hye-Kyng,Kim, Sun-Yeon,Kim, Soon-Kyung,Chang, Ock-Ja The Korean Nutrition Society 2000 Nutritional Sciences Vol.3 No.1

The purpose of this study was to examine the intake of Cr, Cu, and Zn, which play important roles in lipid metabolism, and the relationship of these microminerals with serum lipids of healthy college living in the Choongnam area. The nutritional status of the subjects(35 women) was evaluated based on anthropometric measurements, 24-hr dietary recall for 3 days. Three-day meals and fasting blood were collected to analyze Cr, Cu, and Zn. The mean age, height, weight and BMI were 20 years, 158 cm, 55kg and 22.42kg/$m^2$ respectively. The mean daily energy intake was 85.9% of RDA for Koreans. The ratio of energy from carbohydrate, protein and fat was 60 : 24 : 16. The mean daily intake of Cr, Cu, and Zn was 60.07 $\mu\textrm{g}$/day, 2.64 mg/day, and 11.35 mg/day, respectively. The mean serum levels of Cr, Cu, and Zn were 143$\mu$g/dl, 81.34$\mu$g/dl, adn 101.54$\mu$g/dl, respectively. The mean serum levels of total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol were 158.56mg/dl, 29.27 mg/dl, 56.00mg/dl, 6.12mg/dl, respectively. In conclusion, the subjects of the present study were healthy and consumed normal levls of dietary Cr, Cu and Zn, which play roles in lipid metabolism. Therefore, serum lipids of the subjects were all in the normal range. There was no significant correlation between dietary microminerals and serum lipids.

일부 지역 산업체 남성 근로자들의 체적지수, 영양소 섭취상태 및 혈청지질 성상에 관한 연구

이성희,노숙령 대한영양사협회 1999 대한영양사협회 학술지 Vol.5 No.1

This study aimed at investigating correlation of nutrients intake and serum lipids of industrial workers. 226 for adult aged 20yr~59yr (average age 35.9yr) were selected as subjects during 6 months, from June to December, 1997. Nutrients intake was investigated by questionnaire, 24-hour recall method. Antropometric assessments, serum lipids and blood pressure of the subjects were investigated. The results as follows: In total subjects, calories, calcium, vitamin A, vitamin B_1 and vitamin B_2 were below Korean RDA(recommended dietary allowances) and protein, iron, vitamin C. niacin and phosphorus were above Korean RDA. Distribution of BMI groups were underweight groups(7.9%). normalweight groups(63.3%) and overweight groups(28.8%). In BMI groups, intakes of calories, carbohydrates, protein, fats, iron, niacin and potassium of overweight groups were higher than those of other groups, significantly(P<0.001). Intakes of calcium of underweight groups were lower than those of other groups, significantly(P<0.05). BMI increased with age. Total cholesterol, triglyceride, apo(b) and atherogenic index of overweight groups were higher than those of other groups, significantly(P<0.001). Calories, carbohydrates, protein, fats, iron, vitamin B_1, vitamin B_2, niacin, natrium and potassium were positively correlated with BMI, significantly(P<0.001). Calcium and vitamin C were positively correlated with BMI, significantly(P<0.01). vitamin A and phosphorus were positively correlated with BMI, significantly(P<0.05). Total lipid, total-chol.. triglyceride. apo(b) and atherogenic index were positively correlated with BMI, significantly(P<0.001). HDL-chol. were negatively correlated with BMI, significantly (P<0.001). Above results, The more BMI and age increased, the worse patterns of serum lipid, so that increased atherogenic index that increased risk of atherosclerosis and degenerative chronic disease connected with serum lipid. After classified by BMI, age and lipid pattern, it will be managed individually for health management of industrial workers. Development and application of efficient program will be urgent for harmonious nutrition counseling and guidance.