제2형 당뇨병 환자에서 우연히 발견된 기종성 방광염 1례

박보민,김윤정,이영태,노정현,권수경,김동준,고경수,이병두,임경호,이순희,박정현 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Emphysematous cystitis is an uncommon disease in which bacterias produce gas within the bladder wall and surrounding tissue. Patients with diabetes, neurogenic bladder and chronic urinary tract infection are predisposed to the disease. It is usually caused by E.coli and Klebsiella. Severity of illness ranges from an asymtomatic condition to life threatening cystitis. Succesful management depends on early diagnosis with correction of underlying causes, administration of appropriate antibiotics, establishment of adequate bladder drainage and surgical excision of involved tissue when required. We report a case of 52-year-old woman who did not compain of symtoms of cystitis but epigastric pain, nausea, and vomitting. Emphysematous cystitis was revealed on the abdominal X-ray series incidentally. CT scans of the pelvis showed mottled gas bubble within the bladder. After treatment, the symtoms subsided and plain abdominal film showed no evidence of gas shadow in the pelvic cavity.

위암환자의 위액단백과 Amylase의 분리와 성상에 관한 연구

정부근,고재경,노연희 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1

Amylase activity was measure din gastric juice and cancer tissue of patients with stomach cancer to find out the possible use of the enzyme as a biochemical marker for stomach cancer. Amylase and proteins in gastric juice from patients with stomach cancer were separated by a DEAE-cellulose column chromatography to investigate the enzyme and proteins specific to the stomach cancer. (1)Protein content and amylase activity were not changed in gastric juice of patients with gastritis and duodenal ulcer, but significantly increased in gastric juice of patients with stomach cancer. The positive rate of protein content and the enzyme activity in the gastric juice as a marker for stomach cancer was relatively high. (2)Protein content in the stomach cancer tissue was significantly increased and amylase activity was greatly increased in 3 cases out of 12 cases of the stomach cancer tissues studied. (3)Substrate specificity and effect of halogen ions on amylase in gastric juice of patient with the stomach cancer was similar to those on the enzyme in the stomach cancer tissue. (4)DEAE-cellulose columkn chromatography revealed that proteins in gastric juice were separated into 8 peaks in the stomach cancer and into 6 peaks in the control. Amylase in the gastric juice was separated by the chromatography into 2 isozymes in the stomach cancer, but not in the control. Substrate specificity for the two gastric juice amylase isozymes was observed to be different. These results indicate that protein content and amylase activity in the gastric juice could be used as a biochemical marker for the stomach cancer and that amylases specific to the stomach cancer appear to be released from the stomach cancer tissue.

유아의 창의성 수준에 따른 언어표현력의 차이

노영희(Noh, Young-Hee),장연주(Chang, Youn-Ju) 한국열린유아교육학회 2011 열린유아교육연구 Vol.16 No.6

본 연구는 유아의 창의성과 언어 능력은 관계성이 있다는 선행 연구에 기초하여 창의성 수준에 따라 문장표현력과 어휘표현력을 하위 요인으로 언어표현력의 관계를 알아보고자 하였다. 이를 위해 만 5세 유아 90명을 대상으로 창의성검사를 실시하고 fox story stem을 제시한 이야기 자료를 수집하여 분석하였다. 연구결과 첫째, 문장 수 평균은 창의성이 높은 집단이 더 높았으며, 집단 간 유의미한 차이는 나타나지 않았다. 둘째, 평균발화길이의 평균은 창의성이 높은 집단이 더 높았으며, 통계적으로도 유의미한 차이가 있었다. 셋째, 창의성이 높은 집단의 9품사(명사, 대명사, 수사, 동사, 조사, 형용사, 관형사, 감탄사, 부사) 사용 평균이 더 높았으며, 특히 명사, 수사, 조사는 통계적으로 유의한 차이가 있었다, 마지막으로, 창의성이 높은 집단의 독창적인 어휘 사용 평균이 더 높았으며 특히 형용사와 조사는 통계적으로 유의한 차이가 있었다. 이러한 연구 결과는 유아 언어 창의성 연구에 유용한 기초자료를 제공하며, 유아의 창의성 발달과 관련된 제 변인에 대한 시사점을 제시하고 있다. The purpose of the study was to investigate the relationship between 5 year-old’s creativity and language expression. The research questions were there are differences in 5 year-old’s language expression according to the creativity levels. The subjects of the study were 90 five year-olds, 44 boys, 46 girls. They attended a child care center and a kindergarten in an urban city, and were in middle income class of Korea. The subjects were grouped into two levels (45 in high level group, 45 in low level group) according to their creativity scores. ‘Teacher’s Creativity Rating Scale for Young Children’ developed by Noh Young Hee, Kim Kyung Chul and Kim Ho (2006) was used for scoring children’s creativity. To measure young children’s language expression, the researcher told each child a sentence of a fox story and asked them to develop the story. Each child’s story was recorded and transcribed. The data was analyzed using t-test, SPSS program. The results of the study are as follows. First, There are no differences in number of utterances according to the creativity levels. Second, there are some significant differences in MLU(Mean Length of Utterances) according to the creativity levels. MLU of high creativity level group was longer than the low creativity level group. Third, there are significant differences in nouns, postpositions and numerals according to the creativity levels. Fourth, there are significant differences in rare adjectives and rare postpositions according to the creativity levels.

Transcriptomic Analysis of Stenospermocarpic Seedless Grape Cultivar, ‘Himrod (Vitis spp.)’ during Inflorescence Development Using RNA-seq

Youn Young Hur,Chan Jin Jung,Sung-Min Jung,Jung-Ho Noh,Jong-Chul Nam,Kyo-Sun Park,Sung-Hwan Jo,Hee Jae Lee 한국원예학회 2013 한국원예학회 학술발표요지 Vol.2013 No.5

협동학습 과정에서의 언어적 행동과 학업 성취도와의 관계

노태희,임희준,박수연 한국과학교육학회 1999 한국과학교육학회지 Vol.19 No.3

본 연구에서는 중학교 1학년 37명을 대상으로 과학 수업에서 협동학습을 실시하고 소집단 협동학습 과정을 녹음/녹화하였다. 이를 토대로 협동학습 과정에서 발생하는 언어적 행동 유형을 범주화하고 이들과 학업 성취도 사이의 관계를 조사하였다. 학생들의 언어적 행동은 크게 학습 내용과 관련된 행동 및 조활동 관리와 관련된 행동으로 구분되었다. 학습 내용과 관련된 행동은 도움 주기, 문제 읽기, 도움 요청하기로 세분되었으며, 이 중 도움 주기 행동이 가장 많았다. 학생들의 언어적 행동과 학업 성취도 사이의 단순 상관 관계를 조사한 결과, 도움 주기와 문제 읽기 행동이 학업 성취도와 정적인 상관이 있었다. 도움 주기 중 구체적인 내용을 제공하는 행동은 학업 성취도와 매우 밀접한 관계가 있었다. 한편, 부분 상관을 통하여 언어적 행동과 학업 성취도 향상과의 관계를 조사한 결과, 상위 수준의 사고를 요하는 적용 영역 성취도의 향상만이 구체적인 내용 제공하기를 비롯한 일부 언어적 행동과 정적인 상관이 있었다. When 37 7th-graders learned science in cooperative learning environments, their small-group processes were audio/video taped. The verbal behaviors that appeared in cooperative learning processes were categorized, and the relationships between verbal behaviors and academic achievement were investigated. Students' verbal behaviors were classified into learning behaviors and management behaviors. Learning behaviors were further coded into giving help, reading problem, and asking help. Giving help was the most frequent behavior among the categories. In studying zero-order correlation between verbal behaviors and academic achievement, giving help and reading problem were found to have positive relationships with academic achievement. Giving specific content, which is a subcategory of giving help, showed the closest correlation with academic achievement. In studying partial correlation between verbal behaviors and the improvement of academic achievement, only application subtest score, which demands higher-order thinking, was positively related with some verbal behaviors including giving specific content.

Chloramphenicol 내성 임상 분리 균주의 Chloramphenicol Acetyltransferase 유전자에 관한 연구

노연희,고재경,김용석 한양대학교 의과대학 1991 한양의대 학술지 Vol.11 No.2

Chloramphenicol resistance (CM) in clinical isolates was studied from a genetic viewpiont. CAT activities were identified from CM-clinical isolates and screening hybridization was performed for the identification of the form of the CAT genes in these strain. Southern and Vouthern hybridiwation were done for the DNA and the RNA from clinically isolated E. coli and S. aureus. The probes used in these hybridization were [α-?P]dCTP-labeled Hind III-Asp I-Mbo Ifragment containing CAT gene of Tn9 from pBR325 DNA, [α-?P]dCTP-labeled Msp I-Mbo Ifragment containing inducible CAT gene of S. aureus from pC194 DNA and [r-?P]APT-labeled synthetic oligonucleotied of 20nucleotide size from and insertion element, IS1. The plasmid CNA from the CM D. coli 178, which was presumed to be transposon (Tn) containing CAT gene was introduced into the wild strain, E. coli HB101 by the cacl₂treatment, and the CAT gene in the transformant was identified by agarose gel electrophoresis and Southern hybridization using [α-?P]dCTP-labeled Hind III-Asp Ifragment of pBR325 DNA as a probe. CAT genes were identified to be widely distribeted in the plasmid DNA and the chromosomal DNA of these clinical isolates and the homology between the constitutively expressed CAT genes of gram positive bacteria, S. aureus was observed by these hybridization. Results obtained by the hybridization using [r-?P]ATP-labeled oliginucleotide consisting 5'-end of IS1 as the probe indicated that CAT henes in the plasmid DNA from these isolates were presumed to be a Tn. The expression of CAT genes was identified by the Northern hybridization. The 4.5 kb and 5.0 kb-sized plasmid DNA from the CM-E. coli 178B, which was presumed to be a Tn containing CAT gene were not identified by agarose gel electophoretic analysis of DNA from the transformant, CM-E. coli HB101. But the cal genewas identified in the chromosomal DNA from the transformant by Southern hybridizagion and the result was interpreted to be the outcome of transposition of CAT gene into the chromosomal DNA of the transformant. With these results, the CAT gene in the 4.5 kb and 5.0 kb-sized plasmid DNA from CM-resistant E. coli 178B was presumed to be a Tn and the other CAT genes which were found to be sidely distributed in the plasmid DNA of the other climical isolates were considered to be a Tn. The multiple drug resistance ezpressed by these clinical isolates might be the result of the sepuential transposition of such genetic elements, Tn. The study on Tn carrying CM and the other drug-resistant genetic elements was considered to be the key target in the genetic viewpoint for the investigation of the multiple drug resistance.

포유자돈 설사에 있어서 콕시듐 원충과 대장균 감염의 상관 관계

노재욱,박경윤,윤희정 한국수의공중보건학회 1999 예방수의학회지 Vol.23 No.2

Analysis of Highly Expressed ESTs Related to Defense Responses in Rhizobium vitis - Infected Tamnara Grapevine

Youn Jung Choi,Hae Keun Yun,Kyo Sun Park,Youn Young Hur,Jeong Ho Noh,Seok Tae Jeong,Myung Sang Ryu,Hee Jae Lee 한국원예학회 2009 한국원예학회 학술발표요지 Vol.2009 No.5

Pharmacokinetic Characteristics of Ibandronate and Tolerability of DP-R206 (150 mg Ibandronate/24,000 IU Vitamin D3) Compared to the Ibandronate (150 mg) Monotherapy in Healthy Adults

Hee Youn Choi,Mi Jo Kim,Yo Han Kim,Yook-Hwan Noh,Jae-Won Lee,Tae‑won Lee,Min-Gul Kim,Kyun-Seop Bae 대한임상약리학회 2014 Translational and Clinical Pharmacology Vol.22 No.1

Ibandronate (a bisphosphonate) is commonly used as an treatment of osteoporosis in combinationwith vitamin D. Monthly DP-R206-a novel, fixed-dose combination tablet (150 mg ibandronate/24,000 IU vitamin D3)-was recently developed to enhance patient compliance. This open,randomized, two-period crossover study was conducted to compare the pharmacokinetics of ibandronatewhen administered as DP-R206 or 150 mg ibandronate to healthy adult volunteers. Eachvolunteer was randomly allocated to receive single-dose DP-R206 or ibandronate with a 28-daywashout period between treatments. Blood samples were assessed using pharmacokinetic analysis. Plasma ibandronate concentrations were determined using liquid chromatography-tandem massspectrometry. Safety and tolerability assessments were performed throughout the study. In total, 103participants received the study drugs and 72 participants completed the study. The geometric meanratios (DP-R206/ibandronate) of the maximum concentration (Cmax) and the area under the plasmaconcentration time curve from time zero to the last concentration (AUClast) values were 0.959 (90%CI: 0.820–1.120) and 0.924 (90% CI: 0.805–1.060), respectively. The frequencies of adverse events(AEs) and drug reactions were similar between treatment groups, and all AEs were recovered withoutsequalae. Ibandronate pharmacokinetics, tolerability, and safety are comparable when administeredto healthy individuals, regardless if administered as DP-R206 or ibandronate.

A study on the analysis of complex cultural spaces in colors and material characteristics

Noh, Moon-sik(노문식),Yang, Deguan(양덕권),Yoon Ji-yuong(윤지영),Rhee Youn-hee(이윤희) 한국색채학회 2008 한국색채학회 학술대회 Vol.2008 No.-