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The composition and the conservation value of Heungchungmu(興淸舞)
Yoon Sil Choi,Me Suk Kim 한국체육철학회 2014 움직임의철학 : 한국체육철학회지 Vol.22 No.1
Yeonsangun(燕山君) gathered the court dancers and named them ‘Heung cheong’ in 1504. The researcher, Yoon-Sil Choi who learned the techniques of Gyobangdance(敎坊舞) from Su-Ak Kim, composed a new dance ‘Heungchungmu(興淸舞)’ which expressed the lives of Heungcheong, based on Gyobangdance(敎坊舞). Choi also founded ‘Heungchungmu(興淸舞) Preservation Institute’. Heungchungmu(興淸舞) Preservation Institute strives to preserve Heungchungmu(興淸舞) by establishing branches in the following areas: starting from Seoul, Jeju, Kyong-gi, North Jeonla, South Jeonla, North Chungcheong and South Kyungsang; and by constantly performing in National Gugak Center and rural areas. There has been no studies on Heungchungmu(興淸舞), thus it is required to conduct research on the subject in order to properly pass down Heungchungmu(興淸舞). The purpose of this paper is to provide academic basic data in order to succeed and develop Heungchungmu, and continuously research the social and cultural preservation value of it. This study discusses the origin, dance motions, music, traditional clothing and accessories, and artistic features of Heungchungmu(興淸舞). To conclude, Heungchungmu(興淸舞) has the intrinsic characteristics of Gyobangdance(敎坊舞), hence may be a sole solution to succeeding Gyobangdance(敎坊舞) accurately. Moreover, it is necessary to designate the dance as Important Intangible Cultural Properties of Korea and get politic support for development and succeed of Heungchungmu(興淸舞).
문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6
Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.
Yoon, Young-Sil,Lee, Jae-Ho,Hwang, Sung-Chul,Choi, Kyeong Sook,Yoon, Gyesoon Nature Publishing Group 2005 Oncogene Vol.24 No.11
Transforming growth factor β1 (TGF β1) is a well-characterized cytokine that suppresses epithelial cell growth. We report here that TGF β1 arrested lung epithelial Mv1Lu cells at G1 phase of the cell cycle with acquisition of senescent phenotypes in the presence of 10% serum, whereas it gradually induced apoptosis with lower concentrations of serum. The senescent arrest was accompanied by prolonged generation of reactive oxygen species (ROS) and persistent disruption of mitochondrial membrane potential (ΔΨm). We demonstrated that the sustained ROS overproduction was derived from mitochondrial respiratory defect via decreased complex IV activity and was involved in the arrest. Moreover, we verified that hepatocyte growth factor released Mv1Lu cells from the arrest by protecting mitochondrial respiration, thereby preventing both the ΔΨm disruption and the ROS generation. Our present results suggest the TGF β1-induced senescent arrest as another plausible mechanism to suppress cellular growth in vivo and provide a new biochemical association between the mitochondrial functional defects and the cytokine-induced senescent arrest, emphasizing the importance of maintenance of mitochondrial function in cellular protection from the arrest.Oncogene (2005) 24, 1895–1903. doi:10.1038/sj.onc.1208262 Published online 31 January 2005
Case Report : Genotype-4 hepatitis E in a human after ingesting roe deer meat in South Korea
( Ja Yoon Choi ),( Jeong Mi Lee ),( Yun Won Jo ),( Hyun Ju Min ),( Hyun Jin Kim ),( Woon Tae Jung ),( Ok Jae Lee ),( Hae Sun Yun ),( Yeong Sil Yoon ) 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.3
The recent increase in the number of cases of indigenous hepatitis E virus (HEV) infection highlights the importance of identifying the transmission routes for the prevention of such infections. Presented herein is the first case of acute HEV infection after ingesting wild roe deer meat in South Korea. A 43-year-old male presented with abdominal discomfort and jaundice. He had not recently traveled abroad, but had eaten raw roe-deer meat 6-8 weeks before the presentation. On the 7th day of hospitalization the patient was diagnosed with acute viral hepatitis E. Phylogenetic analysis of his serum revealed genotype-4 HEV. This case supports the possibility of zoonotic transmission of HEV because the patient appears to have been infected with genotype-4 HEV after ingesting raw deer meat. ((Iin Mol HepatoI2013;19:309¬314)
한국산 연어의 미토콘드리아 NADH Dehydrogenase Subunit 3 영역의 클로닝 및 DNA 염기서열 분석
최윤실 ( Yoon Sil Choi ),이윤호 ( Youn Ho Lee ),진덕희 ( Deuk Hee Jin ) 한국수산과학회 2003 한국수산과학회지 Vol.36 No.2
N/A Mitochondrial DNAs has been used frequently as genetic markers for the population genetic studies of salmonid fishes. Samples used in this experiment were chum salmons (Oncorhynchus keta) from Korea. We analyzed variation of mitochondrial NADH dehydrogenase subunit 3 gene (ND3) among 4 individuals of the Korea population. Genomic DNA was extracted from the liver of the chum salmon samples. Then, the ND3 gene was amplified by polymerase chain reaction (PCR) including the 3`region of cytochrome oxidase III gene (COIII) and the 5`region of NADH dehydrogenase subunit 4L gene (ND4L). The size of the PCR product was 752 bp and the sequences showed some genetic variation among those four individuals. Genetic variations were observed in 7 sites as single nucleotide polymorphism (SNP). Within the open reading frame of ND3 gene which encodes 116 amino acids, 5 nucleotide substitutions were found. Both transitional and the others of a Japanese chum salmon in Genbank showed 5 sites of SNPs. This study provided the basic information of SNP in ND3 gene among Korean chum salmons and demonstrated the possible use of the SNP data as a genetic marker.
Jun, Chang-Duk,Kim, Yurim,Choi, Eun-Yong,Kim, Minsun,Park, Byungrim,Youn, Byungsoo,Yu, Kangyeol,Choi, Kyu-Sil,Yoon, Kwon-Ha,Choi, Suck-Chei,Lee, Myeung-Su,Park, Kie-In,Choi, Minkyu,Chung, Yeuntai,Oh, Crohn's Colitis Foundation of America, Inc. 2006 Inflammatory bowel diseases Vol.12 No.7
BACKGROUND:: Gliotoxin, a fungal metabolite, has been known to show strong immunosuppressive properties, although its mechanisms are not completely understood. In this report, the authors investigated the mechanism whereby gliotoxin has anti-inflammatory properties in vitro and in trinitrobenzene sulfonic acid-induced colitis. MATERIALS AND METHODS:: Body weight, histological scores, and myeloperoxidase activity were evaluated in trinitrobenzene sulfonic acid colitis. Nuclear factor-&kgr;B (NF-&kgr;B) p65, tumor necrosis factor-α, interleukin (IL)-1&bgr;, IL-12, and intercellular adhesion molecule-1 were detected by immunohistochemical staining. IL-8 secretion was measured by an enzyme-linked immunosorbent assay. Heme oxygenase-1 (HO-1) expression and I-&kgr;B degradation were analyzed by Western blot. RESULTS:: Pretreatment of human epithelial HT-29 cells with gliotoxin significantly blocked the I-&kgr;B degradation and NF-&kgr;B p65 nuclear translocation induced by tumor necrosis factor-α or IL-1&bgr;; these were parallel with the inhibition of IL-8 secretion and intercellular adhesion molecule-1 expression in the same cells. Interestingly, gliotoxin induced HO-1 in HT-29 cells and, in turn, inhibition of HO-1 activity by a zinc protoporphyrin IX reversed the effects of gliotoxin in terms of I-&kgr;B degradation, intercellular adhesion molecule-1 expression, and IL-8 production. In trinitrobenzene sulfonic acid colitis, gliotoxin administration significantly improved the clinical and histopathological symptoms. Notably, gliotoxin also induced HO-1 in the colonic mucosa and zinc protoporphyrin IX reversed the protective effects of gliotoxin in trinitrobenzene sulfonic acid colitis. CONCLUSIONS:: These results demonstrate for the first time that the anti-inflammatory actions mediated by gliotoxin include HO-1 induction and the subsequent blockade of NF-&kgr;B-dependent signaling pathways in vitro and in vivo. The current results also demonstrate that gliotoxin may be an effective agent for the treatment of diseases characterized by mucosal inflammation.
Effect of DBP/PLGA Hybrid Scaffold on Angiogenesis during the Repair of Calvarial Bone Defect
Yoon, Sun Jung,Park, Ki Suk,Choi, Bang Sil,Khang, Gil Son,Kim, Moon Suk,Rhee, John M.,Lee, Hai Bang Trans Tech Publications, Ltd. 2007 Key Engineering Materials Vol.342-343 No.-
<P>This study was designed to investigate the influence of demineralized bone particles (DBP)/PLGA hybrid scaffold on angiogenesis and osteogenesis in a calvarial defect model. DBP/PLGA scaffolds were manufactured by solvent casting/salt leaching method, and each scaffold contained 0, 10, 20, 40, and 80 wt% DBP of PLGA, respectively. A total of 34 rats were operated and bicortical holes were placed on their calvaria. The defects were filled with different ratio DBP/PLGA scaffolds. After 3, 7, 14, and 28 days, specimens were taken and, histologic, immunohistologic and RT-PCR analyses were carried out concerning number of vessels and density of regenerated bone, and angiogenic activation. On days 7, in all experimental groups, bone formation occurred in a direction from defected margin of calvarium to center of implanted scaffold and new vessel formation took place in front of the osteogenic regeneration front. We found that the 20 and 40 wt% DBP/PLGA scaffold was superior in its ability to regenerate new bone, induced more intensive formation of microvasculature and expressed in a higher level of osteocalcin mRNA than other groups.</P>