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초고속 광통신용 Avalanche photodiode의 제작 및 특성에 관한 연구
유지범,박찬용 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2
We review the characteristics of Avalache photodiode(APD) for long haul and high bit- rate optical fiber communication system including basic operating principle, excess noise factor, and bandwidth, and we also summarize recent progress. Separate absorption garding, charge and multiplication APD with charge plate layers instead of guard ring was designed and fabricated using metalorganic chemical vapor deposition and reactive ion etching technique. APD shows 37∼48V of breakdown voltage and very low dark current less than 10 nA at 90% of breakdown voltage. Receiver consisting of APD and Ga As pre - amplifier shows sensitivity of - 33.6dBm in the application of the pseudorandom 2^23-1 non- returen- to- zero(NRZ) patterns at 10^-9 bit error rate(BER).
Systemic Lupus Erythematosus를 동반한 Multiple sclerosis
이지현,이기주,윤성호,부귀범,손현화,박유환,정춘해,김진호,정원영 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2
Multiple sclerosis and lupus erythematosus are chronic, potentially disabling diseases of unknown cause. It is a rare occasion that the finding of both diseases occurs in one patient. Because both diseases may affect the central nervous system, it may be difficult at times to differentiate symptoms of lupus erythematosus from those of multiple sclerosis. As far as we know, there was no case report of SLE in multilple sclerosis in Korea. We report a case of multiple sclerosis accompanied by SLE.
류옥현,류혜진,박수연,권순범,박상수,김희영,이계원,서지아,오정헌,김신곤,김난희,최경묵,백세현,최동섭 대한내분비학회 2004 Endocrinology and metabolism Vol.19 No.1
저자들은 국내에서 처음으로 음핵 비대와 지속적인 질출혈을 주소로 내원한 19세 여성에서 고혈압이 동반되지 않으면서 11 -수산화효소 결핍으로 인한 선천성부신증식증을 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다. Congenital adrenal hyperplasia refers to a group of autosomal recessive disorders that is defective in the synthesis of cortisol. The enzymes most often affected are 21-hydroxylase and 11 - hydroxylase. The low levels of cortisol stimulate the pituitary gland to release ACTH. Chronic elevation of the ACTH level causes bilateral adrenal hyperplasia and a secondary increase in androgen formation. We examined a 19 year-old woman presented with clitoral hypertrophy and vaginal spotting. The subjects basal level of serum cortisol was low, but the serum levels of ACTH, 17a-hydroxyprogesterone, deoxy-corticosterone were elevated. The urinary excretions of 17-ketosteroids and 17-hydroxycorticosteroids were also increased. The karyotyping study and transrectal ultrasonography showed normal findings. The patient underwent clitoris reduction surgery and received hydrocortisone. To the best of our knowledge, this is the first case of 11 -hydroxylase deficiency in Korea (J Kor Soc Endocrinol 19:58∼63, 2004).
Genome-Wide Association Study of Rice Core Set Related to Grain Weight
( Buung Choi ),( Ji-min Yoo ),( Sang-beom Lee ),( Gyeong-jin Kim ),( Kyu-won Kim ),( Ji-hyock Yoo ),( Kyeong-seok Oh ),( Byeong-churl Moon ),( Wook-han Kim ),( Yoo-hyun Cho ),( Sang-won Park ),( Yong- 한국육종학회 2018 Plant Breeding and Biotechnology Vol.6 No.3
Rice is being consumed in over 50% of the world's population, and it is main food in Korea. Many accessions of rice have been utilized for breeding purposes such as the use for functional food, disease resistance, improved quality and yield. In this study, the 1000-grain weight, one of important components for yield in rice, was investigated and analyzed by conducting a genome-wide association study (GWAS) using whole genome SNP genotype data on 295 Korean rice core sets. Four genes, Os01g0315700, Os03g0604566, Os04g0413500 and Os05g0216950, are significantly associated with 1000-grain weight. We presume carefully that the function of these kind genes will help in the selection of intermediate parents with high yield and genetic markers to develop new varieties.
( Ji Oh Mok ),( Chan Hee Jung ),( Chul Hee Kim ),( Chang Beom Ryu ),( Yeo Joo Kim ),( Sang Jin Kim ),( Hyeong Kyu Park ),( Kyo Il Suh ),( Myung Hi Yoo ),( Dong Won Byun ) 대한내과학회 2013 The Korean Journal of Internal Medicine Vol.28 No.6
Background/Aims: This study was performed to compare the mucosal findings after esophagogastroduodenoscopy in two groups before and after the use of alendronate only and following administration of the enteric-coated alendronate (5 mg) and calcitriol (0.5μg) combined drug (Maxmarvil, Yuyu Co.). Methods: The study population consisted of 33 postmenopausal healthy female volunteers, aged 50 to 70 years (mean age, 58 ± 5) without gastrointestinal symptoms and with normal baseline endoscopic findings. Esophagogastroduodenoscopy was performed at baseline and was repeated 2 weeks later after daily intake of Maxmarvil (n = 17 subjects) or alendronate only (n = 16 subjects). Mucosal injury scores were reported by an endoscopist after 2 weeks of treatment with each medication schedule. Results: Esophageal mucosal injuries developed in two of 16 subjects in the alendronate only group and 0 of 17 in the Maxmarvil group. Gastric mucosal injuries developed in eight subjects in the alendronate group and four subjects in the Maxmarvil group; this difference was statistically significant. Conclusions: The mucosal damage scores for the alendronate group (total score 24) were significantly higher than those for the Maxmarvil group (total score 9) in the esophagus and stomach. Therefore, this study suggested that enteric-coated Maxmarvil is less harmful to gastrointestinal mucosa than alendronate, and may improve the tolerability of osteoporosis medication in clinical practice.
Yoo, Ji-Hyock,Park, Sang-Won,Kim, Won-Il,Lee, Sang-Beom,Oh, Kyeong-Seok,Moon, Byeong-Churl,Kim, Sung-Chul 한국토양비료학회 2017 한국토양비료학회지 Vol.50 No.6
Heavy metal(loid) contamination of rice is the main issue in abandoned metal mine area with regard to food safety. A field study was conducted in mine area to see if soil amendments treatment including calcium superphosphate, sulfur, steel slag and S-containing fertilizer could reduce As and/or Cd content in rice grain and increase the growth of rice. The As content in brown rice reduced to 60% compared to the control only in $7.0Mg\;ha^{-1}$ of steel slag treatment. Cd reduction in rice was thought to be not the effect of amendments but the result from the difference in growth and development of rice plant and this could be ascribed to low soil Cd availability to rice plant. Compared with control, increased rice yield of cultivar Hwanggeumnuri was 1.3~2.2 and $1.5Mg\;ha^{-1}$ in calcium super phosphate and S-containing fertilizer treatment, respectively and the trend was also observed in cultivar Ungwang. However, steel slag treatment reduced the Ungwang yield by $0.4{\sim}0.9Mg\;ha^{-1}$. Future work will be needed to establish the agricultural measure with which secure the safety and yield of rice simultaneously.
Depression and Anxiety in Korean Patients with Chronic Obstructive Pulmonary Disease
( Ji-Yong Moon ),( Tae-Hyung Kim ),( Yeon-Mok Oh ),( Joon Beom Seo ),( Kwang Ha Yoo ),( Ji-Hyun Lee ),( Eun Kyung Kim ),( Seunghee Baek ),( Woo Jin Kim ),( Jin Hwa Lee ),( Sang-Min Lee ),( Sang Yeub L 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.0
Background: Depression and anxiety are common comorbidity in COPD patients, and they could have potential impact on clinical outcomes of COPD. Objective: We assessed the prevalence of depression and anxiety in Korean COPD patients, and also investigated whether co-morbid depression or anxiety show clinical differences in the course of COPD. Methods: Using Korean Obstructive Lung Disease (KOLD) Cohort from 15 university hospitals in Korea, we analyzed the prevalence of depression and anxiety by using Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). We also compared demographic data, comorbidity, lung function, frequency of acute exacerbation, mortality related or unrelated with COPD, emphysema index and quality of life measured with St George Respiratory Questionnaire for COPD patients (SGRQC) between depression or anxiety patients with non-depression or non-anxiety patients, respectively. Results: Among 217 patients with COPD, the prevalence of depression and anxiety were 37.8% and 27.2%, each. Depression and anxiety were closely correlated with each other. Patients with depression or anxiety had higher BODE index, higher SGRQC score and more frequent acute exacerbation for following 3 years. After controlling for confounders including age, sex and BODE index, presence of depression or anxiety had no significant impact on frequency of acute exacerbation. Conclusion: Based on BDI and BAI, depression and anxiety are common in Korean patients with COPD, and may influence variable aspects of COPD.
P106 Needle-free jet injection of hyaluronic acid improves skin remodeling in a mouse model
( Ji Yeon Hong ),( Won Jong Oh ),( Young-je Kim ),( Kwang Ho Yoo ),( Beom Joon Kim ),( Myeung Nam Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Newly developed needle-free microjet injection device is a novel technique for introducing various materials into the skin without causing pain or bleeding, but its mechanism of action, efficacy and safety are not yet fully observed. Objectives: The purpose of this study was to investigate the mechanism of action, efficacy, and safety of the needle-free pneumatic injection using hyaluronic acid (HA) solution with a mouse model. Methods: We evaluated the efficacy and safety of a microjet device that pneumatically accelerates a jet of HA solution under high pressure into the dermis of mouse skin. We examined the treatment effects using skin hybrid model jet dispersion experiments, photographic images, microscopy, and histological analyses. Results: Use of the pneumatic injection device successfully increased dermal thickness and collagen synthesis in our mouse model. The mechanisms by which pneumatic injection using HA solution exerts its effects may involve increased dermal thickening, triggering of a wound healing process, and activation of vimentin and collagen synthesis. Conclusion: Collagen synthesis and increased dermal thickening were successfully achieved in our mouse model using the microjet device. Pneumatic injection of HA under high pressure provides a safe and effective method for improving the appearance of mouse skin.
( Ji Yeon Hong ),( Won Jong Oh ),( Kwang Ho Yoo ),( Kapsok Li ),( Beom Joon Kim ),( Chang Kwun Hong ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Thread lifting has become increasingly popular both for physicians and patients for its advantages in limited scarring, rapid recovery, and minimal complications compared with the incisional surgery. The usage of nonabsorbable polypropylene thread has especially been favored because of its durability. A 45-year-old woman presented with a protruding mass on the left temporal area for 2 years. She had a history of thread lifting 8 years ago. Histologic examination of biopsy specimen revealed a dense inflammatory cells`` infiltration in the dermis. This case emphasizes the importance of consistent and long-term follow-up evaluations to determine whether thread lifting causes delayed type complications.