제2형 당뇨병 환자의 심혈관계 자율신경병증과 상완-발목 맥파속도

김신곤 대한내분비학회 2011 Endocrinology and metabolism Vol.26 No.1

복부 대동맥류의 임상적 고찰

김신곤,김동의,배문오,정상영 대한혈관외과학회 1994 Vascular Specialist International Vol.10 No.1

Eighteen cases of abdominal aortic aneurysms(AAA) were surgically treated between May 1991 and April 1994 at the Department of Surgery, Chonnam University Hospital. Patients were devided into elective and emergency cases and analysed on the basis of sex, age, chief complaints, associated diseases, size of aneurysm, operating time, mortality and cause of death. Initial presentation was usually abdominal or back pain in elective cases but palpable mass and abdominal distension in emergency cases. Hypertension was the most common associated disease(67%). Ten of 11 emergency cases were ruptured. There was no positive relationship between the size of AAA and the incidency of the rupture. There was no death in elective cases, but 7 ruptured AAAs were died in l 1 emergency cases (63.6%). Overall surgical mortality was 38.9%. The causes of death were acute renal failure(2), myocardial infarction(2), postoperative bleeding(2), and sepsis(1). For AAAs, surgical intervention is recommended and operation must be performed before rupture regardless of the size.

한국에 있어서 외국어습득의 최적연령층에 관한 연구 ( A Study on the Optimal Age Bracket of Foreign Language Acquisition in Korea )

김신곤 마산대학교 1983 論文集 Vol.5 No.2

지식의 유형과 지식표상에 관한 일 고찰

김신곤,김준규 한국교육사상연구회 1999 敎育思想硏究 Vol.8 No.-

수술후 소화불량증상을 호소하는 환자에 있어서 종합소화효소제 Romantase^(�)정의 임상효과

김신곤,윤정한,유종선 中央醫學社 1992 中央醫學 Vol.57 No.6

In general, the patients complain the indigestive complaints with variable degree after any operation because of metabolic and physiological disturbances following longterm strain and none per oral. Postprandial fullness, epigastric discomfort, bloating, and loss of appetite were included in these indigestive complaints. Indeed the such complaining postoperative patients can not try intake per oral enough to meet for recovery phase, and should induce many complications and significant weight loss, steatorrhea, deficiency of calcium, anemia, and susceptibility to infection. So we examined the effect of diggstive-Romantase� on postopetative patients who complain many typed indigestive manifestations. The results were follows. 1. Improvement rates on subjective symptoms were 93.3 % on postprandial fullness, 83.3 % on bloating, 76.5 % on loss of appetitie, 75.9 % on nausea and vomiting, 75 % on epigastric discomfort. 2. Overall improvement rate was 82.9 % on any typed postoperative patients with indigestive complaints. 3. There was no side effects following administration of Romantase�. In conclusion, Romantase� is a safe and effective digestive on any typed postoperative patients with indigestive complaints.

A Survey of MIS Success Measures

김신곤 韓國外國語大學校 經營情報大學院 MIS硏究所 1988 Mis硏究 Vol.2 No.1

한국 성인에서 C-reactive Protein과 대사성 증후군의 상관성에 관한 연구

김신곤,김동림,신동현,김난희,최경묵,백세현,최동섭 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.2

Background: Metabolic syndrome (MS) is characterized by insulin resistance accompanied by one or more of the following: obesity, hypertension, impaired glucose tolerance, low HDL cholesterol levels, and/or hypertriglyceridemia. However, the precise underlying pathogenic mechanism of MS is not known. Several recent reports have suggested a positive association between components of MS and markers of the acute-phase response, including C-reactive protein (CRP). These results imply that MS is accompanied by an ongoing inflammatory process. The purpose of our study was to evaluate the association between circulating levels of C-reactive protein, a sensitive systemic marker of inflammation, with components of metabolic syndrome in Korean adults. Methods: A total of 1,461 subjects aged between 20 and 81 years, who visited the Health Management Center at Korea university between November 2000 and February 2001 were studied. We investigated the correlation between CRP levels and components of MS. The components of MS were categorized, and age-sex adjusted mean values of CRP calculated for the categorized components. The BMI was categorized into 5 classes, and the CRP levels examined according to their BMI class. In addition, subjects with a different number of the MS components were grouped as follows: group 1 for 0 components, group 2 for 1 components, group 3 for 2 components and group 4 for ≥ 3 components, and the CRP levels calculated for each group. Results: There were significant positive correlations of CRP levels with age, BMI, TG, systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBS), uric acid, insulin, and homeostasis model assessment IR (HOMAIR). A significant inverse correlation was observed between CRP levels and serum HDL. From the multivariate analysis, age and BMI were significantly correlated with CRP levels. The means of the CRP for the categorized components of MS were significantly higher in the BMI categories: ≥25 for female/27 for male, TG ≥200 ㎎/dL, fasting plasma glucose ≥126 ㎎/dL and blood pressure ≥140/90 ㎜Hg, and the CRP levels by BMI class were: 1.19 (BMI <18.5), 1.54 (BMI 18.5∼22.9), 1.59 (BMI 23.0∼24.9), 1.77 (BMI 25. 0∼29.9) and 2.07 (BMI >30.0) ㎎/L. Furthermore, the increase in the CRP levels in relation to the numbers of MS were 1.46 (group 1), 1.70 (group 2), 1.95 (group 3) and 2.11 mg/L (group 4) with statistical significance. Conclusion: The above data showed associations between the CRP levels and the different components of MS. This might suggest that MS in Koreans could be accompanied by a systemic inflammation response

특집/우리나라 당뇨병의 현황

김신곤,최동섭 대한의사협회 2008 대한의사협회지 Vol.51 No.9

Diabetes mellitus has approached to us as a social epidemic in Korea. The prevalence of diabetes in Korea has increased five to six-fold from 1.5% to 7~9% during the past 30 years. This increasing rate is remarkably high in comparison with those of developed countries such as the USA- doubled during the past 30 years. In addition, diabetic complication is very common in Korean diabetic patients. For example, a total of 70.5% among new patients who were started with renal replacement therapy had diabetes mellitus. Furthermore, diabetes-related mortality has rapidly increased over the last 20 years. The age-sex adjusted mortality rate of diabetic patients was about three-fold higher than those of general population. As a result, medical cost of diabetes mellitus covered by the national health insurance corporation was 3.2 trillion won and accounted for 19.2% of all medical costs. On the other hand, the rate of awareness and treatment in diabetic patients has improved from 1998 to 2005. However, the proportion of adequate glycemic control (HbA1c < 7%) among the treated diabetic patients was only 40%. The comprehensive and integrated health intervention including public approach is urgently needed to control the increasing prevalence of diabetes mellitus and its related undesirable outcomes.

영어의 명사 대명사의 굴절에 관한 연구

김신곤 창원대학교 1982 논문집 Vol.4 No.-

고대 영어와 현대 영어에 있어서의 어순의 차이점

김신곤 창원대학교 1979 논문집 Vol.1 No.-