만성중이염의 골도청력변화

박선홍,노용훈,이도용,나한조,김용기,최봉남,도남용 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

We have usually experienced bone conduction impairment in chronic otitis media, but it is unclear that raised bone conduction threshold is due to the reflection of cochlear dam- age and / or Carhart effect ( an artificial elevation of bone conduction threshold due to conductive defect ) or both. The purpose of this study is to verify the influence of the artificial elevation of the bone conduction threshold in chronic otitis media and to estimate Carhart effect. A total of 336 cases of tympanoplasty with unilateral chronic otitis media without any other causes of sensorineural hearing loss was studied. The average threshold levels of the bone conduction in diseased ears ranged from 18.5dB at 4kHz to 12.1dB at 250Hz The longer duration of the disease, the larger perforation size, the more severe damage of the middle ear structure and the presence of the cholesteatoma made bone conduction threshold increased. The postoperative thresholds of bone conduction were Improved in 36 cases (40.4%) of the 89 cases that underwent operation with type I tympanoplasty technique without electrie drilling. The degree of the maximal improvement was 14.3dB at 2000Hz and the minimum was 8.8dB at 250Hz. but these result did differ from a statistically significant degree. The result suggest that the bone conduction threshold in chronic otitis media is elevated artificially by conductive defect and improved by successful reconstructive surgery.

鱗片 및 珠芽에 對한 低溫處理와 光中斷이 暖地型 마늘의 生育과 二次生長에 미치는 影響

韓海龍,朴庸奉,張田益 제주대학교 1984 논문집 Vol.19 No.-

濟州在來의 珠芽,普通鱗片과 上海早生의 珠芽 및 普通鱗片에 各各 30日,60日間의 低溫(0~5℃)處理를 하여 2月 20日부터 5月 20日까지 120分間을 光中斷處理를 하여 이들 處理가 마늘의 生育 및 鱗莖形成에 미치는 影響을 調査하였다. 1. 濟州普通鱗片은 冷藏處理 其間이 길수록 出現이 빨랐고 珠芽는 길수록 늦은 경향을보였다. 2. 草長,葉長은 普通鱗片이 珠芽보다 컸으며 低溫處理기간이 길수록 增加하였다. 上海早生의 普通鱗片은 自然日長區가 光中斷處理區 보다 增加하였다. 3. 葉墅長 및 葉墅莖은 低溫處理 其間이 길수록 增加했으며 특히 上海普通鱗片은 60일 低溫區에서 光中斷處理 效果가 크게 나타났다. 4. 鱗莖肥大率은 冷藏處理 其間이 길수록 普通鱗片에서 높았고 濟州普通鱗片은 30,60일,上海普通鱗片은 60日 冷藏處理에서 光中斷處理 果가 컸다. 5.珠芽의 植物體重과 球重은 冷藏處理 期間이 길수록 減少했으며 普通鱗片에서도 光中斷處理는 오히려 增加하였다. 6. 鱗片數는 上海珠芽를 제외하고 30日 冷藏處理에서 많았다. 7. 收量은 普通鱗片이 珠芽보다 많았고 光中斷處理는 上海早生의 無處理區와 60일 冷 藏處理구에서 增加하였다. 8.GA₃ 의 含量은 각 處理에 관계없이 鱗片肥大 最盛期에 增加하였으나 收穫期에 가까 울수록 減少하는 傾向을 보였다. Garlic seed bulbils of ecotypes,Cheju Jaere and Shanghae wase,were planted after treatment at 0-5℃for 30 and 60 days respectively, and treated night interruption (120 min) pretreated with low temperature from 20th February to 20th May. The results are summarized as follows. 1.With an increment of the period of low temperature, sprouting of Cheju common clove tended to early while bulbil was late. 2. Plant height, leaf length,leaf sheath length and neck diameter were all promoted by exposure to longer low temperature. however common clove of Shanghae wase grew better during natural day than with night interruption. 3. Bulbing was promoted by longer low temperature in common clove and Cheju Jaere common clove. Treatment for 30 and 60 days at low temperature plus 120min.night interruption showed the most significant increases. 4. Plant weight and bulb weight of bulbils decreased with longer low temperature but in common clove they were increased by night interrutpion. 5. The clove number of the shanghae wase bulbil incresed with 30 days low temperature treatment. 6. Yields per 10a of common clove increased more than bulbils and Shanghae common clove when treated for 60 days at low temperature plus 120 min. night interrutption. 7. GA content incresed at the clove enlargement period,but decresed with the approach of the harvest period.

직업적 연폭로에서 혈중 연량 수준에 따른 선별검사로서의 혈중 ZPP 검사의 타당도

한구석,안현철,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to evaluate the validity of current screening criteria of lead exposure and to provide effective information for the better health management of lead workers, author investigated the interrelationship between blood lead and blood zinc protoporphyrin(ZPP) and evaluate the validity of blood zinc protoporphyrin as the screening test and blood lead as gold standard of diagnostic test. The total of 2245 lead workers (male workers: 1982, female workers : 263) from 12 lead using industries were studied. Blood lead, ZPP, hemoglobin and hematocrit were selected as lead exposure variables. Personal information on sex, age and work duration were also checked. Blood lead was measured with flameless atomic absorption spectrometry (model: Hitachi 8100) using standard addition method. Blood ZPP was measured with portable hematoflurometer (model: Aviv 206). The results obtained were as follows: 1. The mean blood lead of all lead workers were 0.7±14.3㎍/㎗(Male: 31.0±14.4㎍/㎗, Female: 28.2±12.9㎍/㎗), whereas the mean blood ZPP of those were 68.1±47.5㎍/㎗(Male: 63.9±43.7㎍/㎗, Female: 100.1±61.0㎍/㎗). The mean value of hemoglobin and hematocrit of all lead workers were 14.5±1.5g/㎗(Male: 14.7±1.3g/㎗, Female: 12.3±1.2g/㎗) and 45.4±3.6(Male: 46.2±2.8, Female: 39.5±3.1) respectively. 2. Validity of test using blood zinc protoporphyrin as screening test for blood lead levels of 30㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 50 and 90 ㎍/㎗ of ZPP respectively, showing 50 and 60 ㎍/㎗ of ZPP for all lead workers. While those test for blood lead levels of 40㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 and 90 ㎍/㎗ of ZPP respectively, showing 60 ㎍/㎗ of ZPP for all lead workers, those test for blood lead levels of 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 or 70 and 100 ㎍/㎗ ZPP respectively, showing 60and 70 or 80 ㎍/㎗ of ZPP for all lead workers. 3. Predictive value of test using blood zinc protoporphyrin as the screening test for different blood lead levels of 30, 40, 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that positive predictive value of screening test were decreased by the increase of blood lead level regardless of csreening criteria value ZPP and negative predictive value of screening test were increased accordingly regardless of screening criteria value of ZPP. On the other hand, within same blood lead level as a gold standard positive predictive values were inceased by the increase of screening criteria value of ZPP, whereas the negative predictive value were decreased accordingly by the the increase of screening criteria value of ZPP. 4. The correlation analysis of all lead workers among study variables revealed that CPbB and natural log transformation ZPP(LZPP) were better correlated with other variables and found to be better estimate than PbB and ZPP themselves. The age was correlated with all other variables, but the work duration was not. The correlation analysis of male and female workers among study variables revealed the same results with all lead workers. 5. The slope of simple linear regression of CPbB (independent variable) with ZPP in female workers(3.223)was steeper than in male workers(2.144). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But there was no slope difference between two groups divided by their work duration of 2 years less and more. The slope of simple linear regression of CPbB lead (independent variable)with ZPP in lead workers whose blood lead were higher than 30㎍/㎗and 40㎍/㎗ were steeper than those whose blood lead were less than 30㎍/㎗ and 40㎍/㎗. 6. The slope of simple linear regression of CPbB (independent variable) with ZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead. 7. The slope of simple linear regression of CPbB (independent variable) with LZPP in female workers(0.0308was steeper than in male workers(0.0253). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But where was no slope difference between two groups divided by their work duration of 2 years less and more. While the slope of simple linear regression of CPbB lead (independent variable) with LZPP in lead workers whose blood lead were hogher than 30㎍/㎗ was not steeper than those whose blood lead were less than 30㎍/㎗, there was no slope difference between two groups whose blood lead were less than 40㎍/㎗ and more than 40㎍/㎗. 8. The slope of simple linear regression of CPbB (independent variable) with LZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead, but the difference was not significant then that of CPbB and ZPP. With above results, it is recommended that the screening criteria value of ZPP should be down to 60-70㎍/㎗ from 100㎍/㎗ for male lead workers and screening criteria of ZPP for female lead workers was all right with current value of 100㎍/㎗. So it is recommended to make different screening criteria of ZPP for male and female workers like the hemoglobin and hematocrit screening criteria. It is also preferable to use CPbB and LZPP rather than uncorrected PbB and ZPP in the evaluation of lead exposure for lead workers.

酪農經營珍斷에 關한 調査硏究 : 釜山市 酪農家를 中心으로

韓鳳羽,金容斗,李秉達 東亞大學校 1968 東亞論叢 Vol.5 No.-

本 調査硏究는 酪農經營의 合理化와 酪農所得의 極大化를 圖謀하기 爲한 方策을 究明하기 爲하여 着手한 것으로 釜山市內 酪農家中에서 20戶를 選定하여 1967年 5月 1日부터 11月 30日까지 經營實態의 調査와 分析을 通하여 經營의 改善點을 發見하고 經營의 合理化 方案을 提示하였는데 그 結果를 要約하면 다음과 같다. 1. 飼育頭數 225頭中 窄乳牛 120頭, 乾乳牛 18頭, 育成牛(♂包含) 87頭며 窄乳牛率(窄乳牛 頭數/總飼養 頭數×100) 53% 乾乳牛率(乾乳牛 頭數/成牛 頭數×100) 13% 育成牛率(育成牛 頭數/成牛 頭數×100) 63%였다. 2. 窄乳牛(乾乳牛 包含) 138頭의 1頭 年平均 産乳量은 3,690kg였다. 3. 窄乳牛에 對한 飼料給與量은 1日 1頭 平均 濃厚飼料 9.4kg 粗飼料(風乾物) 9.0kg이며 養分含量은 TDN 9.09kg, DCP 1.24kg인데 標準(NRC)보다 TDN 53%, DCP 82%를 過量供給하고 있다. 한편 粗飼料量이 全體飼料量의 50% 未滿인데 이것은 經濟面이나 乳牛能力 增進面으로 볼 때 不利함으로 60% 以上으로 하여야 한다. 4. 生産費의 項目別 比率은 飼料費 44%, 勞動費 27%, 肥料 및 材料費 5%, 賃貸料 및 地代 5%, 乳牛 및 建物償却費 16%, 小農具費 및 其他 3%로 되어있다. 5. 牛乳生産費는 牛乳 1kg當 平均 32.25원인데 1kg當 乳價가 43.2원이기 때문에 牛乳 1kg當 10.95원의 收益을 얻고 있는데 牛乳 1kg當 28원 以下가 되도록 努力하여야 한다. 6.1頭當 年平均 勞動時間이 470時間인데 1人이 8~10頭를 管理하려면 365時間 以下가 되어야 한다. 7. 調査한 酪農家中 黑字經營이 14戶, 赤子經營이 6戶인바 年間 1頭當 純收益이 平均 2萬원으로 所得率이 낮았다. 8. 酪農經營의 診斷에 있어서 牛乳代와 飼料 및 勞動費만을 가지고 經營의 採算點을 生産面에서 把握하는 것은 簡易한 判斷을 爲하여 意義 있는 일이며 今般 調査한 結果를 보면 牛乳代 17,596원, 粗收益中 牛乳代 比率 86%, 飼料 및 勞動費 11,781千원, 生産費中 飼料 및 勞動費 比率 71%이므로 採算指數(牛乳代÷粗收益中 牛乳代比率/飼料 및 勞動費 ÷生産費中 飼料 및 勞動費比率=粗收益/生産費)는 1.29가 된다. 1頭當 年 35,000원의 所得을 爲해서는 採算指數가 1.5가 넘어야 한다. 蛇足 본 調査硏究는 1967年度 文敎部 學術硏究 助成費로 이루어진 것으로 硏究費를 補助해준 文敎當局에 對하여 深甚한 謝意를 表하는 바이다. 또한 調査에 協力하여 주신 釜山市牛乳協同組合과 釜山市 酪農家 畜産同人 諸位에 對하여 깊은 感謝를 드리는 바이다. This report aims to get a rationalization of dairy fanning and maximization of dairy income. In order to gain the suvey, I have selected -'0 dairy farm-houses in Pusan city. Then I have been caught some points of farm improvement and presented some rational plan of dairy farming through farm business survey and analysis from 1 May to 30 Nov. 1967. The summalized results of the research are as follows; 1. Out of 225 heads were milking-cow 120 heads, dry-up-cow 18 heads, rasing cattle 87 heads. 2. Average milk yield per a year of 138 heads milking-cow(including dry-up-cow) was 3.690kg. 3. Average 9.4kg of concentrate and 9.Okg of rougiiage(air dry matter) for milking-cow per a head were the daily feeding ration, nutrient content was 9.09kg of TDN and 1.24. kg of DCP, these content were more 53% of TDN and 82% of DCP than feeding standard (NRC). 4. The feed cost was 44%, the cost of labor 27%, manure and materials cost 5%, charge for renting and land rent 5%, depreciation cost of dairy cattle and building 16%, cost of small farming tools and other cost 3% of the total production cost. 5. Average production cost of milk per 1kg of milk was 32.25 won. average profit per 1kg of milk was 10.95 won (milk price was 43.2 won per 1kg). But it may be less than 28 won per 1kg of milk. 6. Average working time per 1 head of a year was 470 hours. But it may be less than 350 hours for the management of 8~10 heads per 1 person. 7. Out of the dairy farm-households surveyed, 11 houses were in the blade farming and 6 houses were in the red farming. Average pure profit per 1 head of a year was gained 20 thousand won that the rate of income may low. 8. Acording to the method of a simply commercial profit was gained to the rate of milk price for the gross profit and the rate of feed and labor cost for the production cost. Average commercial profit index has show 1.29 in the result of this farm survey. Commercial Profit index = milk price/rate of milk price for gross profit/cost of feed & labor/rate of feed & labor cost for production cost x 100 =17,956 thousand won/0.86/11,781 thousand won/0.71 x 100=1.29 It may be over 1.5 of the cmmercial profit index for 35 thousand won of the income per 1 head of a year.

근린약국에서 산제로 조제된 아테놀올정의 안정성

용철순,최한곤,이종달,유봉규 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.4

Prescription filling in powder form is performed in community pharmacy practice to adjust dose for children and patients who cannot swallow whole tablet. However, there are few reports regarding the stability of the active ingredient and possible microbial growth after the medication is dispensed to powder form. This study examined the stability of atenolol, an antihypertensive agent, and microbial growth in the unit dose pouches dispensed at twenty-one community pharmacies located in Taegu area. Randomly chosen first unit dose pouch contained 77.4% of the prescribed dose of the drug and there were only four community pharmacies that dispensed the drug within 10% deviation from the dose prescribed by physician. Surprisingly, there were three community pharmacies that dispensed the drug with greater than 40% deviation, which may pose a major concern regarding the efficacy and safety of the drug prescribed for the treatment of hypertension. Atenolol content during a month did not indicate significant change, showing 5.4%, 4.3%, and 3.3% of decrease in 50%, 80%, and 90% relative humidity conditions, respectively. Microbiological examination during a month showed less than 0.5 microorganism in high power field (hpf) in all the relative humidity conditions tested. Based on this study, pharmacy practice in community pharmacy needs to be rigorously regulated to ensure that the dose of the prescribed drug is properly incorporated into the unit dose pouch dispensed as powder form.

소형엔진의 배출가스측정방법에 따른 질소산화물 및 매연에 관한 연구

한영출,나완용,오용석,문병철,박봉규,박귀열 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.3

Recently, increasing usage of diesel vehicle, many countries try to reduce the pollutant materials by emission regulation standard. Particularly, in our country, the supplement ratio of diesel vehicle is high, and air pollution by vehicle exhaust gas is very serious. So, in study, we tested exhaust gas by various mode in light duty diesel engine. Therefore, we can know about NOx and smoke seriousness.

PLD 박막의 물리적 성질

한용진,조봉균,정재훈,이수빈,박해윤,이태기,채희백,홍진수 순천향대학교 기초과학연구소 1998 순천향자연과학연구 논문집 Vol.4 No.2

Thin amorphous carbon films were deposited by a Q-switched Nd;YAG 532nm with beam power density of ?? on the high purity graphite (99.7%). The pressure of vacuum chamber was ?? Torr. In order to estimate the quality of the Pulsed Laser Deposition films one of the most important optical properties, bandgap energy, was characterized by transmission and reflection in the range of the visible, and an optical direct bandgap energy of 2.45eV and indirect bandgap energy 0.36eV were obtained. Surface morphology of amorphous film was investigated by AFM (Atomic Force Microscopy). Its surface roughness is 70nm. Comparing our results with the published values in the literature we have confidence that our films show the good quality for optical properties.

유리폐기물과 하수슬러지 소각재의 고형화 처리연구

한상목,신대용,윤봉구,김승겸 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

하수슬러지 소각재, 폐유리분말 및 고로슬래그의 고형화에 의하여 건자재를 제조하였다. 하수슬러지 소각재는 SiO_2와 Al_2O_3가 75 wt%, Fe_2O_3가 8.21 wt%, 폐유리분말은 SiO_2 71.4 wt%, Na_2O 14.43 wt% 및 CaO 9.32 wt%, 고로슬래그는 SiO_2 33.4 wt%, CaO 41 wt% 및 Al_2O_3 14.5 wt%를 함유하여 세라믹스 제조원료로 사용이 가능하였다. 하수슬러지를 800℃에서 2시간 하소한 무기질분말을 분쇄하여 하수슬러지 소각재를 제조하였다. 30∼70 wt%의 하수슬러지 소각재, 30∼70 wt%의 폐유리분말 및 10∼30 wt%의 고로슬래그를 혼함하여 950∼1,100℃에서 2시간 소성하여 시편을 제조하였다. 하수슬러지 소각재 첨가량이 감소하고 폐유리분말의 첨가량과 소성온도가 증가하면 부피비중과 압축강도는 증가하였으나 기공률과 흡수율은 감소하였다. 1,050℃에서 소성한 시편(No. 1, 3, 5 및 7)의 부피비중은 1.70∼1.83, 기공률과 흡수율은 0.3∼2.4% 및 0.1∼1.5%, 압축강도 272∼323 kgf/㎠을 나타내었다. 고로슬래그를 첨가하여 1,100℃로 소성한 시편(No. 8, 9, 및 10)의 부피비중은 1.82∼2.11 및 압축강도는 350∼671 kgf/㎠이었다. 하수슬러지 소각재, 고로슬래그 및 시편의 중금속출량은 매립지 침출수배출 허용기준치보다 낮아, 본 연구에서 제조한 시편은 주변 환경에 해가 없어 건자재로의 이용이 가능하였다. An experimental study for the constructional material by solidification using sewage sludge ash, waste glass powder and blast furnace slag was carried out in the senses of waste materials disposal and utilization. The reusability of sewage sludge ash, waste glass powder and blast furnace slag as a raw material in the manufacturing process of ceramics was highly expected because the chemical compositions of these waste materials were mostly SiO_2 and Al_2O_3. Sewage sludge ash was fabricated by calcined at 800℃ for 2 hours and obtained by the crushing. The mixture of 30∼70wt% of sewage sludge ash, 30∼70 wt% of waste glass powder and 10∼30 wt% of blast furnace slag were heated at 950∼1,100℃ for 2 hours. The density and the compressive strength of specimen increased with increasing the sintering temperature and decreasing the addition amount of sewage sludge ash, No. 1, 3, 5 and 7 specimens showed the bulk density of 1.70∼1.83, porosity of 0.3∼2.4%, water absorption of 0.1∼1.5% and compressive strength of 272∼323kgf/㎠. And, that of the No. 7 specimen heated at 1,100℃ increased with increasing the addition amount of blast furnace slag, and for No. 8, 9 and 10 specimens, bulk density was 1.82∼2.11 and compressive strength was 350∼671 kgf/㎠. An extraction test for specimen to detect toxic materials showed below the permitted standard of land-filling extractable heavy metal contents. It was founded that the specimen were useful for the constructional materials.

점화시기 및 당량비 변화에 따른 CNG기관의 성능 및 배출가스에 관한 연구

한영출,오용석,박봉규,김대열,김미수 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.4

Research on the development of CNG dedicated en dine that has important meaning both as a clean fuel and an alterna-tive energy to reduce the exhaust emission horn diesel engine are actively going on these days. In this study, in order to present the direction and application of CNG engine, we tested the CNG engine performance experimented by changing the parameters such as ignition timing, equivalent ratio. The engine performance and exhaust emission were measured by engine performance mode at maximum load condition with increasing the rpm in the range of 1,000∼2,200rpm. Also, the testing engine was heavy-duty CNG dedicated engines with displacement of 11,050cc.

遮光程度가 양하(Zingiber mioga)의 生育, 收量 및 無機成分 含量에 미치는 影響

韓海龍,張田益,朴庸奉 제주대학교 1981 논문집 Vol.13 No.-

양하는 생강과 더불어 중요한 香辛菜蔬지만 濟州道에서는 그 栽培法과 양하의 食用價値를 정확히 모르고 있다. 이에 繁殖方法의 하나로서 遮光程度를 달리하였을 경우 양하의 生育과 收量 및 無機物 含量에 미치는 影響을 調査한 結果는 다음과 같다. 1) 양하의 草長과 葉數는 遮光程度가 높을수록 增加하는 傾向을 보였으나 葉소莖과 葉幅은 生育初期에는 處理間에 비슷한 傾向을 보였으나 生育後期에는 增加하는 速度가 緩慢하였고 遮光程度가 낮을수록 增加하였다. 2) 3.3㎡當 收量은 70%遮光區에서 가장 많았고 處理區는 對照區 보다 多少 增加하는 傾向을 보였다. 3) 줄기와 잎에서는 遮光程道가 높을수록 窒素, 인산, 가리, 마그네슘, 망간의 含量이 對照區 보다 增加하였으나 鐵成分 만은 對照區의 줄기에서 가장 많은 含量을 보였다. 4) 위의 實驗의 結果 양하의 生育, 收量 및 無機成分量은 70%遮光에서 增加하였고 앞으로 遮光程度와 處理時期을 달리하여 계속 硏究할 必要가 있다고 생각된다. Among major condimental vegetables, Zingiber mioga and ginger has not yet been examined in cultivation method and contents of inorganic element in Cheju Island. This experiment therefore was carried out to investigate the effect of several shading treatments on growth, yields and contents of inorganic elements of Z. mioga. The results are as follows : 1) The higher the shading degree, the higher the plant height and leaf number, but neck diameter and leaf width showed no significant difference from the early growth period while the late growth period, the lower the shading degree, the higher the neck diameter and leaf width. 2) In the yields of 3.3㎡ unit area, the 70% shading treatment showed sligh increase in compare with other treatment. 3) In contents of the inogranic element of leaf and stem, the higher the shading degree, the higher the content of nitrogen, phosphor, potassium, magnesium and manganese, but only the iron increased in compare with other treatment at the stem of control lot. 4) The result indicated that the growth, yields and contents of inorganic element increased significantily at the 70% shading treatment. The results also point out that study of different shading degree and shading period are necssary.