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      • 정부 조직개편의 정치권력적 성격 : 김영삼정부'와 '김대중정부'의 중앙행정기구개편 사례 Kim Young Sam and Kim Dae Joong Administrative Cases

        김우식 청주대학교 사회과학연구소 2005 한국사회과학연구 Vol.27 No.2

        이 연구의 목적은 정부조직 개편의 정치권력적 특성을 밝히는 것이다. 이러한 특성은 두 가지 측면에서 나타난다. 하나는 정권의 담당 주체들이 정치적 목적을 가지고 조직개편을 시도하게 되어 처음부터 정치적 성격을 갖고 출발하는 경우가 많다. 또 다른 하나는 정부조직의 개편이 기존의 조직을 변동시키는 적극적 작용이기 때문에 조직 개편이 기존의 이해구조를 변화시키게 됨으로써 이해 당사자들은 변화의 결과 자신의 이익을 극대화하기 위하여 여러 노력을 경주하게 된다. 이러한 과정은 필연적으로 정치권력적 상호작용을 수반하게 되어 정부조직개편은 정치적 성격을 강하게 나타내게 된다. 조직개편의 정치권력적 속성을 밝히기 위하여 김영삼 정부(1993년 2월~1998년 2월)와 김대중 정부(1998년 2월~2003년 2월) 기간 동안에 이루어진 조직개편 사례를 분석 대상으로 선정하여 정치권력적 속성을 비교 분석하였다. 분석에서는 조직개편의 정치적 상황 요인, 조직개편의 목표, 조직개편의 추진세력과 힘의 소재, 조직개편의 의사결정과정, 그리고 조직개편의 결과(내용)를 분석 요소로 선정하였다. Structural reform of government is a power political phenomenon. Reform is accompanied by many changes of invested interests among administrative agencies and bureaucrats. And they are intersted in advantages or disadvantages which the newly reformed structures are able to offer. So power politics is natural in changing world of reforming governmental structures. Two Kim's Adminstratives initiated many important periodical reformations in government structure. Many environmental factors and political reasons made tow Kims push administrative agencies reformation. In the process of reforming changes many revolts has been burst and many interests were struggling for maintaining or expanding their agencies. These problems can be solved by political actions among actors. So power political characteristics is unavoidable in reforming governmental structures. This study focused on and analyzed political characteristics of reorganizing environmental demands, goals of reorganization, locus of power of initiating reform, decision making process and results of reorganized structures in the reformed cases from Kim Young Sam Administrative to Kim Dae Joong Administative.

      • KCI등재후보

        Identification of Genes Modulated by High Extracellular Calcium in Coculture of Mouse Osteoblasts and Bone Marrow Cells by Oligo Chip Assay

        Kim, Hyung-Keun,Song, Mina,Jun, ji-Hae,Woo, Kyung-Mi,Kim, Gwan-Shik,Baek, Jeong-Hwa The Korean Academy of Oral Biology 2006 International Journal of Oral Biology Vol.31 No.2

        Calcium concentration in the bone resorption lacunae is high and is in the mM concentration range. Both osteoblast and osteoclast have calcium sensing receptor in the cell surface, suggesting the regulatory role of high extracellular calcium in bone merabolism. In vitro, high extracellular calcium stimulated osteoclastogenesis in coculture of mouse osteoblasts and bone marrow cells. Therefore we examined the genes that were commonly regulated by both high extracellular calcium and 1,25(OH)_(2)vitaminD_(3)(VD3) by using mouse oligo 11 K gene chip. In the presence of 10 mM[Ca^(2+)]e or 10 nM VD3, mouse calvarial osteoblasts and bone marrow cells were co-cultured for 4 days when tartrate resistant acid phosphatase-positive multinucleated cells start to appear. Of 11,000 genes examined, the genes commonly regulated both by high extracellular calcium and by VD3 were as follows; 1) the expressions of genes which were osteoclast differentiation markers or were associated with osteoclastogenesis were up-regulated both by high extracellular calcium and by VD3; trap, mmp9, car2, ctsk, ckb, atp6b2, tm7sf4, rab7, 2) several chemokine and chemokine receptor genes such as sdf1, scya2, scyb5, scya6, scya8, scya9, and ccr1 were up-regulated both by high ectracellular calcium and by VD3, 3) the genes such as mmp1b, mmp3 and c3 which possibly stimulate bone resorption by osteoclast, were commonly up-regulated, 4) the gene such as c1q and msr2 which were related with macrophage function, were commonly down-regulated, 5) the genes which possibly stimulate osteoblast differentiation and/or mineralization of extracellular matrix, were commonly down-regulated;slc8a1, admr, plod2, lox, fosb, 6) the genes which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were commonly up-regulated;s100a4, npr3, mme, 7) the genes such as calponin 1 and tgfbi which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were up-regulated by high extracelluar calcium but were down-regulated by VD3. These results suggest that in coculture condition, both high extracellular calcium and VD3 commonly induce osteoclastogenesis but suppress osteoblast differentiation/mineralization by regulating the expression of related genes.

      • KCI등재후보

        조혈모세포이식 환자에서 침습성 진균 감염에 대한 이트라코나졸 액과 플루코나졸 시럽의 예방 효과 : 전향적, 무작위, 비교 임상시험

        최수미,이동건,최정현,박선희,엄기성,김유진,김희제,민창기,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2005 감염과 화학요법 Vol.37 No.2

        목적 : 조혈모세포이식 환자에서 호중구 감소 기간 동안 이트라코나졸 액(ITZS)과 플루코나졸 시럽(FCZS)의 진균 감염에 대한 예방 효과를 전향적으로 비교해 보고자 하였다. 재료 및 방법 : 2001년 8월부터 2002년 6월까지 가톨릭 조혈모세포이식센터에 입원하여 동종 조혈모세포이식을 받은 만 18세 이상의 환자들을 각각 ITZS와 FCZS군으로 무작위 배정하여 침습성 진균 감염 발생과 약제 관련 부작용을 전향적으로 조사하였다. 결과 : ITZS군에 40명, FCZS군에 38명이 배정되었고, FCZS군 환자의 평균 나이가 더 많았다. 시험 약제 평균투여기간은 ITZS군 16.4일, FCZS군 21.9일로 ITZS군이 더 짧았다. 이는 ITZS군에서 소화기 부작용으로 인한 약제 중단이 더 많았기 때문으로 보인다. 시험 약제 투여 후 총 빌리루빈 수치의 유의한 증가가 관찰되었으나, 약제 관련 부작용은 모든 환자에서 가역적이었다. 호중구감소 기간동안 표재성 진균 감염은 두 군에서 모두 발생하지 않았고, 침습성 진균 감염은 ITZS군 5명(12.5%), FCZS군 8명(21.1%)으로 FCZS군에서 많았으나, 통계학적으로 유의하지 않았고, 사망률에도 유의한 차이는 없었다. 결론 : 침습성 진균 감염에 대한 이트라코나졸 액과플루코라졸 시럽의 예방 효과에 유의한 차이는 없었으나, 앞으로 더 많은 환자를 대상으로 잘 짝지어진 대조군 연구가 필요할 것으로 보인다. 부작용 중 간독성과 관련하여 이식시 투여되는 여러 약제들과의 상호작용에 대한 연구도 필요할 것이다. Background : Though fluconazole is widely used for antifungal prophylaxis, it is ineffective against mould infections including Aspergillus species. Itraconazole has a broader spectrum than fluconazole but the capsule form shows erratic bioavailability in neutropenic patients. In this study, we compared itraconazole oral solution (ITZS) with fluconazole syrup (FCZS) for the prevention of invasive fungal infection (IFI) in allogeneic hematopoietic stem cell transplant recipients. Materials and Methods : Adults receiving allogeneic hematopoietic stem cell transplantation (HSCT) from september 2001 to June 2002, were randomly allocated to either the ITZS group or the FCZS group. We prospectively evaluated the safety and efficacy of each drug. Results : Out of 78 patients (40 patients in the ITZS group and 38 patients in the FCZS group) who were eligible for this study, 37 patients completed the course of prophylaxis without any evidence of IFI. The mean duration of prophylaxis was 16.4 days for the ITZS group and 21.9 days for the FCZS group (P<0.006). Drug-related adverse events occurred in 28 patients (70.0%) and 19 patients (50.0%) in the ITZS group and the FCZS group, respectively. Common adverse events of ITZS were nausea, vomiting, and diarrhea. Drug-related reversible hepatotoxicity occurred in 4 patients in the ITZS group. There was a significant elevation of total bilirubin level in the ITZS group. The incidence of suspected IFI occurred in 5 patients (12.5%) who received ITZS, compared with 8 (21.1%) who received FCZS (P=0.372). There were no proven IFIs or superficial (oral/vaginal) fungal infections in both groups. Overall mortality was not different between the two groups (2.5% in the ITZS group versus 5.3% in the FCZS group, P=0.610). Conclusion : ITZS and FCZS showed similar protection against IFI during pre-engraftment period. Poor tolerability due to gastrointestinal troubles of ITZS might limit its success as prophylactic therapy. Well matched controlled study with large number of patients will be required in the future.

      • KCI등재
      • 지주막하출혈에 의해 발생한 Takotsubo 심근병증의 1예

        김선영,김우식,박종혁,오명기,권선옥,나종천,조욱현,최석구 인제대학교 2007 仁濟醫學 Vol.28 No.-

        A 64-years-old man was admitted to emergency department with symptom of chest pain. The characteristic of symptom was squeezing pain at substernal area. The patient had a history of hypertension and diabetes mellitus. His electrocardiogram(ECG) showed ST elevation in lead Ⅰ, Ⅱ, V3-6 and his laboratory results revealed mild increase in cardiac enzymes. And his echocardiogram showed apical hypokinesis. Based on the suspicious symptoms and results for acute anterior myocardial infarction, we decided to take a coronary angiogram for further evaluation. However, coronary angiogram revealed normal epicardial coronary arteries. He was admitted at Intensive Care Unit for monitoring and treatment of heart failure. After 3 days of hospitalization, his mental status was changed. His brain computed tomography revealed subarachnoid hemorrhage. After 5 days, hypokinesis of apex was improved to nearly normal on echocardiogram. This is a case of transient left ventricular apical ballooning or takotsubo cardiomyopathy associated with subarachnoid hemorrhage.

      • KCI등재후보

        레진 계열 근관봉함재 Adseal의 세포독성에 관한 연구

        김희정,백승호,이우철,박한수,배광식 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.6

        The properties of ideal root canal sealers include the ability of sealing the total root canal system and no toxic effects to periradicular tissues. Cytotoxicity test using cell culture is a common screening method for evaluation of the biocompatibility of root canal sealers. The purpose of this study was to investigate the cytotoxic effect of newly developed resin-based sealer (Adseal 1, 2, and 3) comparing with those commercial resin-based sealers (AH26 and AH Plus), ZOE-based sealers (Tubliseal EWT, Pulp Canal Sealer EWT) and calcium hydroxide based sealer (Sealapex). An indirect contact test of cytotoxicity by agar diffusion was performed according to the international standard ISO 10993-5. L929 fibroblast cells were incubated at 37℃ in humidified 5% CO₂-containing air atmosphere. The freshly mixed test materials were inserted into glass rings of internal diameter 5 ㎜ and height 5 ㎜ placed on the agar. After the 24 hrs incubation period, the decolorization zones around the test materials were assessed using an inverted microscope with a calibrated screen. A Decolorization Index was determined for each specimen. Adseal 1, 2, and 3 did not exert any cytotoxic effects, whereas AH26, AH Plus, Tubliseal EWT, Pulp Canal Sealer EWT, and Sealapex produced mild cytotoxicity.

      • 리더십 자질론의 통합적 접근과 中庸의 도 : 대척성의 균형적 수용

        김우식 청주대학교 사회과학연구소 2015 한국사회과학연구 Vol.36 No.2

        This article reviews the resurgence of traits approach of leadership and validates Quinn’s new traits approach of leadership which is integrating positively contradictory nature of a certain trait. And it shows historical trends of leadership theories, reviews more trait theory of leadership, and introduces Quinn’s new interating approach of his fundamental leadership. His fundamental leadership approach is jumping positively over the contradictories resulted from traditional dichotomy and becoming harmonious one. The conceptualization is similar with the Doctrine of the Mean. It is not just a middle, but the golden mean fully considerated the extremes. It supports more Quinn’s new concept of integrating contradictories. 본 논문은 리더십 자질론의 재등장과 Quinn의 리더십 자질론에 대한 새로운 접근법을 검토하였다. 리더십의 이해를 위해 리더십 이론의 흐름을 정리하고 초기 리더십 자질이론과 후속 연구를 검토하였으며, 그리고 Quinn의 자질론에 대한 통합적 접근을 검토하였다. Quinn의 근원적 리더십은 우리의 전통적 2분법적 사고의 약점을 뛰어넘어 자질의 대척성을 긍정적으로 통합하는 새로운 자질론 접근법이다. 이어서 중용의 ‘中和’ 개념을 검토하였다. 중화 개념은 양극단을 심사숙고하여 그 중심을 취하여 조화에 이르는 길이다. 이러한 개념은 대척성을 조화로운 하나로 수용하는 것으로서, Quinn의 근원적 리더십과 일치하는 생각임을 확인하였다.

      • 조직통제 메카니즘으로서의 조직신뢰

        김우식 청주대학교사회과학연구소 2015 한국사회과학연구 Vol.36 No.2

        오늘날 조직관리에서 신뢰는 매우 중요하다. 신뢰는 조직의 협동과 협력을 만들 수 있는 좋은 재료이다. 또한 조직에서의 통제는 필연적으로 조직을 목적으로 향하도록 질서를 유지하는 데 불가결한 요소이다. 이 논문에서는 조직에서 신뢰가 필요한 사회적 맥락을 소개하고, 신뢰와 통제의 밀접한 관계를 설명한다. 나아가 이들의 관계를 좀 더 폭넓게 이해하기 위해 조직이론의 여러 패러다임을 소개한다. 즉 신기능주의(체제이론), 구조이론, 신제도주의이론, 노동과정이론, 신푸코이론을 소개함으로써 신뢰와 통제의 관계를 넓게 조망하고자 한다. Todays trust is important for managing all organizations. This article explores the charcteristics of trust for cooperation and collaboratin, especially as control forces and control mechanism which are necessary ingredients in organizations. To understand trust as control mechanism, trust-control relationships are to be explored. And then this paper proceeds to review briefly five social and organizational analysis perspectives which govern their relations and mechanism in organizations. They are neo-functionalism/systems theory, structuration theory, neo-institutional theory, labour process theory and neo-Foucauldian theory.

      • 공직 내 멘토관계와 공무원의 조직몰입과 직무만족

        김우식,엄창용 청주대학교 사회과학연구소 2004 한국사회과학연구 Vol.26 No.1

        본 연구는 멘토관계가 공공조직에서도 존재하는가를 확인하고, 그것이 공무원들의 조직몰입과 직무만족에 어떠한 형태로 영향을 미치는가에 대해 실증적 방법을 통해 분석하는 데 초점을 두었다. 이를 위해 충청북도내 도청 근무자와 2개의 시청 근무 공무원 212명을 대상으로 설문조사를 실시하였다. 분석결과 공무원조직에서도 멘토관계가 광범위하게 존재하며, 멘토관계를 가지는 경우 조직몰입과 직무만족이 높은 것으로 나타났다. 멘티의 경우 교류시점, 접촉빈도 그리고 교류지속여부가 조직몰입에, 그리고 교류지속여부가 직무만족에 영향을 미치는 것으로 나타났다. 멘토의 경우 학력차와 접촉빈도가 조직몰입에, 그리고 직급차가 직무만족에 긍정적 관계를 가지고 있었다. This study examines the existence of mentoring relationships in governmental organizations and pictures out its effects on commitment and job satisfaction by questionaire for 212 public officers employed by Chungbuk Province and tow cities(Chongju and Chungju). Results show that the mentoring relationships exist and those who have a mentor are more intensively committed to their organizations and enjoy higher level job satisfaction than those having not mentor. Mentee's commitment is positively related to contact time point and contact frequencies, and their job satisfaction is positively related to whether or not having contacts now. And mentor's commitment is positively related to education difference and contact frequencies, and their job satisfaction is positively related to status difference.

      • 능동표적신호합성 알고리듬의 실시간 구현

        김희성,김우식,최상문,한동훈,신기철,김재수 韓國海洋大學校 附設 海洋科學技術硏究所 1997 硏究論文集 Vol.6 No.-

        The simulation of target-scattered echo with the moving sonar platform and target in 3-dimensional ocean environment is essential to validate and evaluate the performance of a sonar system. This paper presents the improved target signal simulation on the basis of the highlight(HL) model and its realtime algorithm. In order to simulate the scattering highlight, the highlight is represented as a directional scatterer. The realtime generation algorithm of the target signal is realized by use of DSP chip, TMS320C40, where the 40 channels are equally separated to form a parallel processing task in 4 processors. The presented realtime-version of target signal simulation can be used as a target signal simulator in the development of ACM(Acoustic Counter Measure) and advanced sonar signal processing techniques.

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