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Cytokine and Tumor Environments
Jin Tae Hong1*, Ju Kyung Song, Sun Mi Kwon, Byung Woo Ahn, Youngsoo Kim, Sang Bae Han 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.1
Cytokines are known to function as regulatory molecules that can be produced by virtually every nucleated cell type in the body, including lymphocytes, monocytes/macrophages, epithelial cells, fibroblasts, and many others. Cytokines include lymphocyte-derived factors (lymphokines), monocyte-derived factors (monokines), hematopoietic factors (colony-stimulating factors), connective tissue/growth factors, and chemotactic chemokines. Cytokines released in response to infection can affect tumor development in different ways. When exposed to infectious agents, cytokines are secreted by sentinel cells, such as macrophages and dendritic cells. These cytokines include interleukin 1 (IL-1) and tumor necrosis factor-α, as well as others, such as IL-6, IL-12, and IL-18. When released in sufficient quantities, these molecules can cause inflammation. Chronic inflammation is highly associated with tumor initiation, promotion, and progression. In this article, we review the roles and mechanisms of cytokines in tumor development.
사업장(事業場) 근로자(勤勞者)의 사상체질(四象體質)에 따른 생활습관(生活習慣), 자각증상(自覺症狀), 건강인식(健康認識)에 관(關)한 연구(硏究)
서명효,강홍구,장두섭,왕명자,차남현,김삼태,권소희,정해경,송용선,이기남,Seo Muoung-Hoy,Kang Hong-Goo,Jahng Doo-Sub,Wang Myoung-Ja,Cha Nam-Hyun,Kim Sam-Tae,Kwon So-Hee,Jung Hae-Kyoung,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2003 대한예방한의학회지 Vol.7 No.2
The study was conducted to evaluate the difference of life style, subjective symptoms and health cognition depending on the Sasang Constitution in the industrial workers. The results were as follows ; Constitutional distribution among exposed group were Tae-eum In(38.4%), So-eum In(35.2%), and So-yang In(26.4%) and it was turned out that Tae-eum In took a higher portion of Sasang constitution than other constitutions in technician workers. 'Exercise' and 'Obesity' were found most in Tae-eum In, In So-eum In there were many 'Normal' weight and 'Having digestive disorders' were found most in So-eum In. There were no significant difference in the health cognition among the constitutions. The closer to 'normal' weight, the higher prevalence in 'having' concern about health condition and the more 'normal' condition in sleeping, the higher prevalence of 'having' self-confident in present health.
도로경관의 자연환경성 모형 : 교외지역 국도를 중심으로 Focused on the National Road in Suburb Areas
홍영록,권상준,조태동 한국환경과학회 2004 한국환경과학회지 Vol.13 No.6
This study was attempted to review the information data for minimizing the destruction of environmental naturalness and the visual damage of landscape from road construction by establishing a model of environmental naturalness for national roads in the suburb areas to suggest an answer to a research question. "What does decide the environmental naturalness of roadscape?". We found that 1) The road-side slope showed no statistical significance in the description of environmental naturalness of roadscape. but the fact that the road-side slope from road construction is the destruction of natural topography cannot be overlooked. 2) In terms of the direction of value variations for independent variables, signboard and telegraph post, soundproofing and protection wall. structure, and building acted toward negative (-) direction, while mountains, sky, road trees, fields, and surrounding green including the road-side slope acted toward positive(+) direction. 3) The variable with highest relative contribution to dependent variables among independent variables is building. which has importance as many as 148 times of road-side slope, while the variable road-side slope has the least importance. Building has the importance of 7.22 times. mountains 5.51 times, road trees 2.59 times, surrounding green 2.54 times, structure 2.41 times, signboard and telegraph post 2.37 times, soundproofing and protection wall 2.20 times, and sky 1.32 times of the fields as a standard criterion values 1.
단백뇨를 보이는 사구체 질환 및 당뇨병성 신병증에서의 Lp(a)
권태환,김준홍,조성,김석재,김용림,조동규,백미영 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1
Background: Recently there has been evidences that serum Lp(a), an independent risk factor to atherosclerotic cardiovascular diseases, were increased in proteinuric disorders such as nephrotic syndrome and diabetic nephropathy. Methods: We intended to search of altered concentrations of Lp(a) in proteinuric disorder measuring serum Lp(a) concentrations with ELISA in 44 glomerulonephritic patients(25 nephrotic syndrome(NS), 19 non-nephrotic range proteinuric glomerulonephritis(GN), 25 diabetic nephropathy patients(DN), and 31 healthy controls(HC). Also, we compared Lp(a) concentration between glomerulonephritis patients and diabetic nephropathy patients with proteinuria of similar degree. Results: 1) There were significantly increased levels of total choesterol, triglyceride, and LDL-cholesterol in Ns compared to GN, DN, HC. 2) There were significantly increased concentrations of serum Lp(a) in NS compared to HC, but no signiicant difference in serum Lp(a) among NS, GN, and DN. 3) There was no significant difference in serum Lp(a) concentrations between NS & DN with 24 hour urine protein greater than 3.0g. 4) There was no significant difference in serum Lp(a) concentration between GN with 24 hour urine protein greater than 0.5g and less than 1.5g and DN with proteinuria of simial degree. 5) In glomerulonephritis patients, there was negative correlation between serum Lp(a) concentration and serum albumin level but correlation with 24 hour urinary protein, total cholesterol, Ldl-cholesterol, and HDL-cholesterol was not shown. In diabetic nephropathy, there was no significant correlation among serum Lp(a) concentration and all parameters including serum albumin, 24 hour urinary protein, and other lipid profiles. Conclusion: The present study confirmed that patients with nephrotic syndrome of diverse etiologies have makedly increased plasma level of Lp(a), in conjunction with other lipid abnormalities. However, this study shows no difference in Lp(a) concentrations between diabetic nephropathy and glomerulonephritis with similar degree of proteinuria.
홍봉식,김태균,오승엽,김환우,권오석 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(A)
The currenty offered experiment courses are completely reconsidered and reconfigured. The whole subjects are divided into 10 seperate courses, each of which should represent either basic or advanced stages of differing fields of the electronic engineering. It has been aimed that the courses form an elaborate hierachy so that they are minimally redundant but linked to one another in their fringes. Also, it has been pursued that the new courses should not fall obsolete in at last next five years exploring the maximum possibilities of the currently available equipments.
옥정호수계에 있어서 화학적 및 생물학적 오염도 지표조사
권태영,강경홍,박기남 전주대학교 자연과학종합연구소 1997 전주대학교 자연과학연구소 학술논문집 Vol.10 No.3
A inveatigation in water system in Okjung lake for the pollution loading and self purification capacity, the nitrate concentration, as a pollution loading index, was 0.2-0.3mM in Sumjin river and Sangchi stream. Imsil stream was mainly pollution source in water system of Okjung lake. Nitrate concentration of Okjung lake was 0.06-0.1mM. This results was mean that the capacity of self-purification of Okjung lake have in reserve.
강인한 퍼지 디지털 PI+D 제어 시스템의 설계 및 구현
권태익,이재홍,김승철,설재훈,임영도 동아대학교 정보기술연구소 2001 情報通信硏究所論文誌 Vol.9 No.1
In this paper, Fuzzy Digital PI+D Controller plans for load, noise, plant change, Fuzzy Controller makes use of simple four rule and membership function, and plant used three phase Induction Motor. Characteristic of system compared from experimentation respectively the proposed Control System, Digital PID Control and Digital PI+D Control System.