아급성기 대량 재해 지역에서의 의료 지원 : '99 대만 지진 의료 지원을 중심으로

송형곤,강보승,송근정,정연권 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: There was a powerful earthquaken(Richter Scale 7.6) In Tiawan, on Sep.21, 1999. We supported the organized medic긴 services in that area during 5 days. Methods: We made the protocol and analyzed the results prospectively. Results: We took care of a total of 708 patients from sep. 23 to sep. 27. Traumatized patients related to the earthquake were 245(34.6%), and most of them had minor injuries. Two hundred thirty-nine(239, 33.8%) patients visited us for medical disease related to living in a group. There were 29(4.1%) patients who complained of neuropsychiatric problems due to the post-earthquaken stress. Because the condition of the patients was so bad, 18(2.5%) were transferred to receive more medical services. Conclusion: In disaster area, organized medical services have two different roles, especially in the subacute stage. One is responsibility for real emergency medical care, and the other is medical care of non-emergency patients.

백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

아파트 단위평면의 구성면적변화에 따른 거주후 평가(POE)에 관한 연구

송대호,장승재,박춘근 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

The study is presented the model by Stepwise Multiple Regression Analysis, practiced Post Occupancy Evaluation with factor which is to be considered for the change of constituent area after grasping change of constituent area. Apartment unit plan composition is classified in private space, public space, supporting space. The results are as follows: Total constituent area ratio of the existing plan was 39.5 : 40.8 : 19.7 and dwelling consciousness one was 36.4 : 44.0 : 19.6. Compared private space with public space, public area requested increase rather than private area. The Multiple Regression formula between each factor and the constituent area is represented to by HY(Cl)=0.3118+0.52483(C2)+0.28383)C3)+0.10922(C6), but estimate ability of this formula comes into 53.3%.

치성 각화성 낭종에 대한 고찰

송승희,이선재,조갑주,서영진,고부일,유기준,박영주,안병근 한림대학교의료원 1994 人間科學 Vol.18 No.11

중년 이후의 남성에 있어서 알콜 섭취가 C-reactive protein 및 관련인자들에 미치는 영향

권대근,성동진,김승권,송영주 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of the present study was to investigate the effect of C-reactive protein level and related risk factors such as T-chol, TG, uric acid and albumin in middle-aged Korean men with the frequency of alcohol consumption. The subjects of the present study was 94 men of 50-years old ages men in Seoul, Korea. The subjects were classified into 3 groups by Frequencies of alcohol consumption as follows ; non-alcohol consumption group (NA), light alcohol consumption group(LA: once or twice per week), heavy alcohol consumption group(HA: drinks more than 3 times per week). The CRP and T-chol, level of HA group was higher than compared to NA group(p<.05). In terms of TG, UA and albumin concentration. there was no significant difference. however. the value of TG was slightly higher trend in the HA group. The relationship between CRP & TG, UA was shown to significantly inverse correlation and the relationship between CRP & albumin was shown to significantly reverse correlation(p<.001, respectively). From these results. there was suggested that CRP and related cardiovascular rise factors were increased with frequency of alcohol consumption and high level of blood CRP, TG, UA are potential risk factors of cardiovascular disease factors in middle-aged korean men.

Rat의 복강에 삽입한 Filorouracil-Polyglycolic acid제형의 Fluorouracil용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitioneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adenocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

Rat의 복강에 삽입한 Fluorouracil-Polyglycolic acid 제형의 Fluorouracil 용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitoneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adcnocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

마라톤후 발생한 열사병 1례

강보승,이정훈,송형곤,송근정,정연권 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Heat stroke, a medical emergency, occurs when the body's thermal regulation is upset and unable to dissipate adequate amounts of heat with a rise in body temperature. It is characterized by hyperpyrexia, with a core temperature of 40˚C or more. hot dry skin, and central nervous system disturbance and usually results in rhabdomyolysis and multiorgan failure. Our case, a 43-year-old healthy male, was caused by a marathon, half course, on a sunny day in late summer. He suddenly fell down on the road and was delivered to a nearby hospital, where a seizure developed. He was transfered to our hospital and then displayed Central Nervous System disturbance, hot dry skin, acute liver failure, rhabdomyolysis, anurlc acute renal failure, and disseminated intravasculular coagulopathy. He was treated with general supportive care and hemofiltration. Despite the aggressive management, he died of shock on the fifth day after admission.

播種期 및 栽植密度가 단옥수수와 찰옥수수의 이삭形質에 미치는 影響

鄭丞根,許成秀 충북대학교 농업과학기술연구소 1992 農業科學硏究 Vol.10 No.1

This study was conducted to clarify the effects of planting time and planting density on ear characters in sweetcorn and waxycorn and, therefore, to provide informations necessary to improve quality and marketability of sweetcorn and waxycorn ears. Sweetcorn cultivar Goldencrossbantam 70 and a local waxycorn variety were planted on May 6 and June 26 at the planting densities of 4,000,6,50 and 9,000 plants per 10a. Plant and ear height were reduced as planting date was delayed and planting density was increased in both sweetcorn and waxyxorn. In sweetcorn, unhusked and husked ear weights were decreased about 60∼80g as planting was delayed and about 10∼20g as planting density was increased. In waxycorn, both planting date and planting density did not inf1uenced on ear weight. In sweetcorn, unhusked, husked and filled ear lengths wers reduced about 2∼4㎝ as planting date was delayed and about 1㎝ as planting denisty was increased. In waxyxorn, ear length was not affected by planting date or planting density. In both sweetcorn and waxycorn, distribution and variations of ear weight and length were smaller for husked ears than those for unhusked ears. Number of kernel rows per ear was decreased in June 26 planting, but planting density showed no influence in sweetcorn. However, both planting date and planting density did not sow any effect on row number in waxycorn.