요부수핵탈출증에서 Thermography의 진단적 가치

신현택,신승우,송재철,정석희,이종수,김성수,신현대 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Objectives : Lumbar radiculopathy is a common disease in oriental rehabilitation medicine. It can be diagnosed by physical examination, plain X-ray, Myelography, CT, MRI, EMG etc. But those methods are not useful in observing the clinical procedure. Objectvie evaluating the clinical procedure is very important in treatment of lumbar radiculopathy. Mehthods : We studied the clinical efficacy of thermography in lumbar radiculopathy during conservative managements. We studied 36 patients with lumbar radiculopathy convinced by MRI. The had low back pain and radiating pain on one side. Thermography had taken before an after 4 weeks treatments, and compared with clinical procedure Results and conclusions : Thermography is not pertinent as a primary diagnostic method in lumbar radiculopathy, but useful in observing the clinical procedure. And it can be recommended as a objective evaluation for lumbar radiculopathy.

CdSe ; Cu 광전도 cell 제작

신영진,정태수,신현길,김택성,정철훈,이훈,신영신 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

筋骨格系 領域에서 Thermography의 臨床的 活用에 對한 考察

신현택,정석희,이종수,김성수,신현대 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

근골격계 질환은 임상에서 가장 흔하게 접할 수 있는 대상의 하나로 그 진단과 평가가 매우 중요하며 여러 가지 진단기기와 평가방법이 이용되고 있다. Thermography는 기존의 진단기기와 달리 질병의 기능적인 측면을 평가할 수 있다는 점과 통증과 같은 주관적인 표현을 어느정도 객관화할 수 있다는 점에서 임상적 가치가 고려되고 있다. 본 연구는 최근 국내외의 임상 논문을 대상으로 근골격계 영역에서 Thermography의 활용 동향을 고찰하여 진단적 가치를 확인하고자 하였다. Thermography는 척추신경병증, 근막동통증후군, 말초신경병증, 반사성 교감신경 이영양증, 레이노증후군, 악관절 장애 및 일부 기타 질환에서 적용되었으며, 대부분의 질환에서 보조적인 진단기기로 활용가치가 있었다. 특히, 질병의 경과 관찰과 약물 및 기타 처치에 대한 효과 판정에 유용하였으며, 레이노 증후군 및 반사성 교감신경 이영양증과 같은 질병에서는 일차적인 진단기기로도 활용이 가능하였다. 향후 근골격계 영역에서 Thermography의 보다 폭넓은 적용을 위해서는 질환에 따른 적절한 촬영방법의 개발 및 결과 판독에 대한 객관성 확보가 있어야 할 것이다. The purpose of this study is to assess the usefulness of thermography in patients with musculoskeletal disease. Thermography is noninvasive, easy to reading, objective and physiologic instrument by measuring and imaging infrared energy emitted from skin surface. Thermography can show the skin temperature changes in various conditions of the body with musculoskeletal disease. This literature review was done for the usefulness of thermography in diagnosing musculoskeletal disease. In conclusion, thermography was adapted in radiculopathy, MPS, peripheral neuropathy, RSD, Raynaud's phenomen, TMJ dysfunction, etc. It was useful as a secondary diagnostic method in those diseases, also possible as a primary diagnostic method in RSD, Raynaud's phenomen. And, it might be reliable tool for estimating disease procedure and consequence after treatment. But, the objectivity of the reading and the development of the operating method are required for further adaptation in musculoskeletal disease.

筋骨格系 領域에서 Thermography의 臨床的 活用에 對한 考察

신현택,정석희,이종수,김성수,신현대 동국대학교 한의학연구소 2000 東國韓醫學硏究所論文集 Vol.8 No.2

근골격계 질환은 임상에서 가장 흔하게 접할 수 있는 대상의 하나로 그 진단과 평가가 매우 중요하며 여러 가지 진단기기와 평가방법이 이용되고 있다. Thermography는 기존의 진단기기와 달리 질병의 기능적인 측면을 평가할 수 있다는 점과 통증과 같은 주관적인 표현을 어느정도 객관화할 수 있다는 점에서 임상적 가치가 고려되고 있다. 본 연구는 최근 국내외의 임상 논문을 대상으로 근골격계 영역에서 Thermography의 활용 동향을 고찰하여 진단적 가치를 확인하고자 하였다. Thermography는 척추신경병증, 근막동통증후군, 말초신경병증, 반사성 교감신경 이영양증, 레이노 증후군, 악관절 장애 및 일부 기타 질환에서 적용되었으며, 대부분의 질환에서 보조적인 진단기기로 활용가치가 있었다. 특히, 질병의 경과 관찰과 약물 및 기타 처치에 대한 효과 판정에 유용하였으며, 레이노 증후군 및 반사성 교감신경 이영양증과 같은 질병에서는 일차적인 진단기기로도 활용이 가능하였다. 향후 근골격계 영역에서 Thermography의 보다 폭넓은 적용을 위해서는 질환에 따른 적절한 촬영방법의 개발 및 결과 판독에 대한 객관성 확보가 있어야 할 것이다. The purpose of this study is to assess the usefulness of thermography in patients with musculoskeletal disease. Thermography is noninvasive, easy to reading, objective and physiologic instrument by measuring and imaging infrared energy emitted from skin surface. Thermography can show the skin temperature changes in various conditions of the body with musculoskeletal disease. This literature review was done for the usefulness of thermography in diagnosing musculoskeletal disease. In conclusion, thermography was adapted in radiculopathy, NIPS, peripheral neuropathy, RSD, Raynaud's phenomen, TMJ dysfunction, etc. It was useful as a secondary diagnostic method in those diseases, also possible as a primary diagnostic method in RSD, Raynaud's phenomen. And, it might be reliable tool for estimating dlsease procedure and consequence after treatment. But, the objectivity of the reading and the development of the operating method are required for further adaptation in musculoskeletal disease.

세계태권도연맹 경기규칙 제정 기록의 오류

신현규(Shin, Hyun-Gyu),김영수(Kim, Young-Soo) 한국사회체육학회 2015 한국사회체육학회지 Vol.0 No.60

The purpose of this study was to examine and correct the error about enactment recording of competition rules in World Taekwondo Federation(WTF). Through this study, the following conclusion were drawn; Now official notice recording of enactment on May 28th in 1973 at WTF is wrong. At that time competition rule of WTF was not enacted by Yang’s(2005), Shin’s(2012), elders of Taekwondo, etc. I didn’t found at any references and anywhere. Then competition rule of Korea Taekwondo Association(KTA) applied intactly for the 1st World Taekwondo Championships on May 25 ~ 27 in 1973. Also competition rule of WTF was not enacted until in 1979 to be held biennially from the 2nd to the 4th World Taekwondo Championships by same reason as mentioned earlier. In addition, first amendment on October 1st in 1977 at WTF is wrong for such reasons. Therefore this study was found an estimated competition rule of enactment on May 1st in 1980 by quarterly magazine on April in 1980 at KTA. This competition rules was comprised the 35 article and additional clause. On comparative analysis has considered that this competition rule was the real enactment of WTF. In conclusion, the enactment of competition rule in WTF is not on May 28th in 1973, but on May 1st in 1980. And so the enactment of competition rule in WTF was to correct again recording of enactment May 1st in 1980. Later I hope future studies about amendment of competition rules in WTF.

산화물 초전도체 Bi₂Sr₂Ca_(1-x)Nd_(x)Cu₂O_(8+δ)의 반사스펙트럼에 관한 연구

신재수,송인걸,김현철 대전대학교 기초과학연구소 2002 自然科學 Vol.13 No.1

고상반응법 (solid-state reaction method)으로 산화물 초전도체 Bi₂Sr₂Ca₁xNdxCu₂O_(B)+δ(0≤X≤0.8)시료를 제조하여, 200~3200 ㎚의 영역에서 반사스펙트럼을 측정하고, KK분석을 통하여 실수유전율, 흡수계수, 에너지 손실함수 등을 구하였다. 반사스펙트럼에서 나타난 MIR 밴드는 치환량 X가 증가함에 따라 고에너지 쪽으로 이동하였으며. 에너지 손실함수의 피크는 치환량 X가 증가함에 따라 저에너지 쪽으로 이동하는 것이 관찰되었다. MIR영역에서의 실수 유전율은 치환량 X가 증가함에 따라 그 값이 음에서 양으로 증가함을 알 수 있었다. The Bi₂Sr₂Ca₁, Nd_(x)Cu₂Ox8 6 (0≤x≤0.8) samples were prepared using the solid-state reaction method. The optical reflectivity spectra of these samples were measured in the range from 200 to 3200 nm at the room temperature. The real part of the dielectric constant, the absorption coefficient, and the energy loss function were obtained from the reflectivity spectra through the KK(E;ramers-Kronig) analysis. It was observed that the MIR band shifts to the high energy side and the energy loss peak to the low energy side with increasing x content. We found that the real part of the dielectric constant in the MIR region changes from the negative to the positive with increasing x content.

Alterations in DNA methylation patterns in regenerated Chinese cabbage (Brassica rapa ssp. pekinensis) plants derived from tissue culture

Hyun‑Min Lee,Jee‑Soo Park1,Yun‑Hee Shin,박영두 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.4

Plant tissue culture is an essential tool in biotechnology. However, tissue-cultured plants often exhibit variations that are either genetic or epigenetic in origin, termed somaclonal variations. Among these variations, DNA methylation is an important heritable epigenetic modification that plays a role in a wide variety of biological processes, including gene expression. In this study, we performed bisulfite sequencing of regenerated Chinese cabbage (Brassica rapa ssp. pekinensis) lines to identify DNA alterations induced by tissue culture. Sequencing data from each regenerated line were compared with reference genome sequences, and common differentially methylated regions (DMRs) were detected in the regenerants. To determine changes in expression levels of DMR-containing genes, we performed quantitative reverse transcription-polymerase chain reaction (qRT-PCR) of the target genes and PCR amplification with bisulfite-converted DNA. We identified DMRs between a non-regenerant line and regenerant lines and selected 10 DMR-associated genes that presented annotation information in Arabidopsis or Brassica rapa. Their expression levels were verified by qRT-PCR to determine the relation between methylation state and gene expression. We observed that genes positioned in DMRs significantly correlated with differential gene expression. We also observed similar methylation patterns in the selected DMRs by PCR-based methylation analysis. The results of this study are a valuable resource for the epigenetic analysis of regenerated lines, especially for Chinese cabbage.

加味薏苡仁湯의 消炎效果 및 成分에 關한 硏究

申鉉大,金性洙 慶熙大學校 1985 論文集 Vol.14 No.-

Kamieuiyeeintang is a combined herb medicine which is used to treat inflammatory illness in oriental medicine field. In order to make clear the anti-inflammatory effects on rats and to find the effective constituents of this herb medicine, author extracted the herbs with water and methanol.. The water extracted portion was administered through mouth to rats and the methanol extraction were used as the samples in HPLC injection to find out the anti-inflammatory constituent by comparing the standard oleanolic acid. The following results were obtained. 1. The extract of Kamieuiyeeintang (100 ㎎/㎏) showed high inhibitory percent of 35.40-47.12 on rat. The aspirin (400 ㎎/㎏) which was used as a control showed 10.42-16.68 of the inhibitory percent. 2. Among the nine herbs of this Kamieuiyeeintang Rheum coreanum Nakai showed the highest swelling percent of 80.60 on the rat hind paw and Taraxacum officinale Wigg was the lowest value of 21.85%. 3. On the HPLC chromatogram Rheum Coreanum Nakai has largest number of peaks and Trichosanthes kirilowii Regel had only 1 peak. 4. In comparing with the standard oleanoloic acid, Paterinia scabiosifolia Fischer showed same peak pattern and retention time with the oleanolic acid. 5. It did not make any relationship between of peak on the chromatogram and anti-inflammatory effect. According to the above results, it is concluded that Kamieuiyeeintang is recognized as a therapeutics for inflammatory diseases and contains the same constituent as oleanolic acid which is a standard therapeutics of inflammation.

충남 아산시 소재 도고천과 그 주변부의 식물상

신현철,조수현,최덕호 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

To understand the floral characteristics of Dogo river and its vicinity, the plants distributed along Dogo river were collected at 10 sites from July to October, 1997. From this investigation, it is confirmed that 113 taxa, including 15 naturalized taxa, were distributed at Dogo river and its vicinity. Among them, 12 taxa were hydrophytes, 25 taxa were wetplant and 76 taxa were waterside plants. The plants of four taxa, including Commelina communis, Humulus japonicus, Persicaria thunbergii, and Bidens frondosa, were distributed at 8 sites, and those of 57 taxa were distributed only at one site.

구리 독성에 기인하는 비정상적인 어류행동의 신경생화학적 분석

신성우,조현덕,전태수,김정상,이성규,고성철 한국환경독성학회 2003 환경독성보건학회지 Vol.18 No.2

The goal of this study is to develop a biomarker used in monitoring abnormal behaviors of Japanese medaka (Oryzias latipes) as a model organism caused by hazardous chemicals. Japanese medaka was treated by copper of appropriate sublethal concentrations after starvation for 48 hr, The untreated individuals showed common behavioral characteristics (i.e., smooth and linear movements). Locomotive activity of the fish was monitored using an image processing and automatic data acquisition system. When treated with copper (100 ppb), the fish showed shaking patterns more frequently. As the concentration of copper increased to 1,000ppb, activity decreased, and the fish showed an erratic movement. Fish were exposed to copper at various concentrations (0, 100 and 1,000 pph) for 24 hrs, and acetylcholine esterase (AChE) activity was observed. When fish were exposed to 1,000 ppb of copper, the body AChE activities appeared to decrease but the head AChE activities showed little change. Expressions of tyrosine hydroxylase (TH) protein in the different organs from both head (brain) and body(kidney) portions affected by the copper treatment were analyzed using immunohistochemical technique compared with control. Five organs of the fish (olfactory bulb, hyothaiamus, optic lobe, pons and myelencephalon regions) showed a relatively strong TH protein expression in the control experiment. A differential expression of TH, however, was observed in the treatment (100 ppb and 1,0M ppb). The treatment (1,000 ppb) significantly suppressed TH protein production in the brain regions. In kidney, however, the same treatment caused little suppression compared with the control. Copper appeared to be less effective in suppression of TH than diazinon, a known TH suppressor. It was concluded that TH could be used as a potential biomarker to monitor the acute copper toxicity in Japanese medaka.