스포츠에 의한 성장기 요추추체종판 장해 분석

김민섭,이종영,이충영,이승훈,임완기,강은균,이종호 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2

Apophyseopathy in human growing-up period is divided in three parts, early stage, advancing stage, and ending stage which are analyzed by X-ray test. The tuber of kantenabtrennung, schmorl and rear oxhorn dissociation are one of the these barrier process. We assume that the fracture of apophysis by overusing is the main cause of these barriers.

괴상석탄재와 폐주물사를 사용한 경량모르터의 물성에 관한 연구

이승한,한형섭,정용욱 啓明大學校 産業技術硏究所 1997 産業技術硏究所 論文報告集 Vol.20 No.-

In this study, bottom ash, lightweight aggregate, and Expanded Polystyrene was used to lighten the mortar. In order to compensate the reduction of strength caused by lightening, the waste foundry sand produced as soild waste was substituted for fine aggregate. As the device of reducing the ratio of absorption, the procedure of mixture was altered to check the effectiveness of surface coating of porous lightweight aggregate. It was observed over 170kg/㎠ compressive strength at about 1.3, and over waste foundry sand, and the ratio of absorption was decreased over 10% by changing the procedure of mixture.

수술후 감염 예방에 대한 Tobra^(R)의 임상효과

이우찬,노승무,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

A clinical study of Tobramycin was performed for prophylactic and therapeutic uses in various diseases. 1. Of 30 cases of postoperative patients, in which Tobra^(R) used, 26 cases(86.7%) were cured without infection, and three cases(3.3%) were improved after mild postoperative infections. 2. Tobra^(R) had good antibacterial action agianst E.coli, Pseudomonas, Enterococcus, Klebsiella and Staphylococcus. 3. Hepatotoxicity, nephrotoxicity, ototxicity and other adverse effects of Tobramycin were not developed in this study.

쓰레기 소각재를 사용한 시멘트 모르터의 물리적 특성에 관한 연구

이승한,정용욱,한형섭,김희중 啓明大學校 産業技術硏究所 1997 産業技術硏究所 論文報告集 Vol.20 No.-

The purpose of this study was to use daily waste incinerated ash, which was reclaimed worthlessly, as substitutes of fine aggregates in concrete. Various kinds of admixture was utilized to strengthen the cement mortar mixed with waste incinerated ash, and altered the curing condition to diminish the rate of expansion. By the results of this experiment, it was possible to produce the lightweight concrete, charactered with the gravity below 1.5 and over 160kg/㎠ compressive strength by replacing all fine aggregates with waste incinerated ash. It was also observed that the low temperature curing condition, lessoned gas exhausts, was effective to increase the strength of cement mortar.

냉기치료후 슬관절강내의 온도변화

백승석,최기섭,박시복,이상건,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

[논문]해석방법에 따른 사각 RC 라멘교의 거동

진치섭,이승훈,엄장섭,배상현 釜山大學校生産技術硏究所 2006 生産技術硏究所論文集 Vol.65 No.-

본 연구에서는 사각(900°~450°) RC 라벤교를 2차원 보해석과 3차원 판해석으로 해석하였다. 연구 결과로부터 다음과 같은 결론을 얻었다. 슬래브 지점부의 단면력 집중에 따라,3차원 판해석에 의한 단면력은 2차원 보해석의 단면력보다 1.015~1.830배 크게 나타났다. 따라서 슬래브 지점부의 철근 보강 영역은 경사폭의 0.11~0.30배로 나타났다. 슬래브 최대 정모멘트 발생각과 라멘교 사각과의 상관관계를 살펴보면, 라벤교 사각 900° ~45°에 대하여 최대 정모벤트 발생각은 93° ~ 51°로 나타났다. 따라서 라벤교의 주인장 철근 이음장 위치는 최대 정모맨트 발생 구역 밖에들도록 해야한다.

Alumina 첨가에 따르는 Hydroxyapatite의 기계적 성질

이승규,이동윤,이영섭,김창은 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.1

For the purpose of improving mechanical strength of hydroxyaptite, various amount of alumina powder were added to hydroxyaptite which were prepared by precipitation method using Ca(NO₃)₂4H₂O and (NH₄)₂HPO₄under the Ca/P mole ratio 1.67 and pH 11. Hydroxyaptite-alumina powder composite were sintered in H₂O gas atmosphere at 1150-1400℃. Adding alumina, hydroxyaptite was decomposed to β-tricalcium phosphate and co-existed with hydroxyaptite. In case of added alumina, bending strength was higher than that of hydroxyaptite. Maximum bending strength was 161MPa at 1300℃, 5.0wt% alumina. Added alumina restrained grain growth of the hydroxyaptite.

알긴산나트륨 및 첨가제를 함유한 서방성 매트릭스 정제

이범진,이태섭,신성이,허보욱,유승구 한국약제학회 1996 Journal of Pharmaceutical Investigation Vol.26 No.3

The matrix tablet containing sodium alginate and CaHPO₄ can release drugs in a controlled fashion from hydrogel with gelling and swelling due to their interaction as water penetrates the matrices of the tablet. The purpose of this study was to evaluate release characteristics of the matrix tablet varying the amount of sodium alginate, CaHPO₄ and other excipients such as chitosan, hydroxypropyl methylcellulose (HPMC) and Eudragit^ⓡ RS100 in the simulated gastric and intestinal fluid. The practically soluble ibuprofen was used as a model drug. The release profiles of matrix tablet in the gastric fluid as a function of sodium alginate/CaHPO₄ ratio was not pronounced because of low solubility of drug and stability of alginate matrices. However, release rate of drug from the matrix tablet in the intestinal fluid was largely changed when sodium alginate/CaHPO₄ ratio was increased, suggesting that the ratio of sodium alginate/CaHPO₄ was an important factor to control the gelling and swelling of the matrix tablet. The incorporation of other excipients into the matrix tablet also influenced the release rate of drug. The chitosan and HPMC decreased the release rate of drug. No release of drug was occurred when Eudragit^ⓡ RS100 was added into the tablet. The retarded release of matrix tablet when excipients were added resulted from the hindrance of swelling and gelling of the matrix tablet containing sodium alginate and CaHPO₄. The hardness and bulk density of the matrix tablet was not correlated with release rate of drug in the study. From these findings, the ratio of sodium alginate and CaHPO₄ in the matrix tablet in addition to incorporation of excipients could be very important to control the release rate of drug in dosage form design.

세로토닌성 항우울제가 백서의 Schedule-Induced Polydipsia에 미치는 영향

이기철,이정호,박중섭,최영민,전성일,정홍경,하준명,정재현 대한생물치료정신의학회 1999 생물치료정신의학 Vol.5 No.2

Object : Schedule-induced polydipsia is considered as an animal model of obsessive-compulsive disorder inrats. The authors evaluated the chronic effects of fluoxetine and clomipramine as serotonergic antidepressants and haloperidol as dopaminergic antagonist on the schedule-induced polydipsia in rat.Methods : Spraque-Dawley rats weighing 200-250gm were individually housed, maintained and allowed free access to water for 1 week. And then the rats were placed on a restricted diet. To induce polydipsia, rats were placed in automatic cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT 60s) feeding schedule over 150-minute test session for a day. Water was available at all times during the feeding schedule in automatic cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 4 groups of rats were administered fluoxetine(5mg/kg/i.p.), clomipramine(5mg/kg/i.p.), haloperidol(0.1mg/kg/i.p.), vehicle(1cc/kg/i.p.) for 3 weeks. Rats were tested once a week to access schedule induced polydipsic behavior. The chronic effects of experimental drugs on schedule induced polydipsic behavior were analyzed with repeated analysis of variance and Scheffe test as a post-hoc comparison.In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5 gm) of food per day which maintained them at their average body weight.Results and Conclusion : The results were as follows ;1) After 4 weeks of daily feeding procedure with fixed time schedule for 60 seconds per day, the experimental group showed significant differences than the control in the amount of water consumption as compared with their baseline water intakes. At the same periods, there were no differences between the experimental group and the control in body weight. 2) The clomipramine treated group and the fluoxetine treated group showed significant decrease in the amount of water intake as compared with their baseline of polydipsic water intakes for 3 weeks of treatment. However, the haloperidol treated group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their baseline of polydipsic water intakes. 3) At 2 weeks of drug treatment, clmipramine treated group(16.88±6.51ml) and the fluoxetine treated group(22.50±10.35ml) showed significantly lower amounts of water intake than the haloperidol treated group (41.25±7.06ml) or vehicle control group(37.50±12.54ml). And also the clomipramine treated group(13.75±5.18ml) and the fluoxetine treated group(18.75±3.54ml) showed significantly lower amounts of water intake than the haloperidol group(35.00±11.65ml) and the vehicle control(34.38±6.78ml) at 3 weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The author confirmed that schedule-induced polydipsia was successfully decreased for 3 weeks of administration of clomipramine and fluoxetine but there was no response to haloperidol.

구내 표준 방사선사진을 이용한 구내방사선촬영기의 선질 평가

이상섭,권혁락,심우현,오승현,이지연,전국진,김기덕,박창서 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : This study was to evaluate the beam quality of intraoral X-ray equipments used at Yonsei University Dental Hospital (YUDH) using the half value layer (HVL) and the characteristic curve of intraoral standard X-ray film. Materials and Methods : The study was done using the intraoral X-ray equipments used at each clinical department at YUDH. Aluminum filter was used to determine the HVL. Intraoral standard film was used to get the characteristic curve of each intraoral X-ray equipment. Results : Most of the HVLs of intraoral X-ray equipments were higher than the least recommended thickness, but the REX 601 model used at the operative dentistry department and the X-707 model used at the pediatric dentistry department had HVLs lower than the recommended thickness. The slopes of the characteristic curves of films taken using the PANPAS 601 model and REX 601 model at operative dentistry department, the X-705 model of prosthodontic dentistry department, and the REX601 model at the student clinic were relatively low. Conclusion : HVL and the characteristic curve of X-ray film can be used to evaluate the beam quality of intraoral X-ray equipment. In order to get the best X-ray films with the least radiation exposure to patients and best diagnostic information in clinical dentistry, X-ray equipment should be managed in the planned and organized fashion. (Korean J Oral Maxillofac Radiol 2000; 30: 183-188)