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남지우,김동욱,배미영,박강순,김정현,노상률,최영일,김희종,장동욱,최소명,권영준,Hikita, S.,Yu, C.,Yoshimura, Y.,Kichimi, H. 성균관대학교 기초과학연구소 1998 論文集 Vol.49 No.-
We investigated the properties of BELLE Time Of Flight(TOF) counter using the data taken in Jan 98 beam test at Pi2 beam line at KEK 12 GeV proton synchrotron. Charge distributions from readout PMT were analysed in comparison with dE/dx distributions predicted by GEANT full simulation. Experimental setup of the beam test is described, then procedures of data analysis, Monte Carlo simulation and analysis results are also described.
국승무(SM Kuk),최성규(SK Choi),민부기(BG Min),최찬(C CHoi),문형배(HB Moon) 대한산부인과학회 1988 Obstetrics & Gynecology Science Vol.31 No.9
본 산부인과학교실에서는 임신 35주의 경산부에서 양수과다증이 동반되었던 Achondrogenesis 1례를 경험하였기에 문헌적 고찰과 함께 보고하는 바이다. Achondrogenesis is a lethal form of congenital chondrodysplasia characterized by extreme micromelia and a marked discrepancy between head and trunk size associated with deficient ossification of vertebrae and pelvis. There are two type of Achondrogenesis, both of which are belived to be autosomal recessive disorders. In Achondrogenesis Type I , both enchonral and membranous ossification are imparied, and in Achondrogenesis Type II , only endochondral ossification is abnormal . We report a case of Achondrogenesis Type I based on grossly radiologic and qutopsy findings with review of literatures.
Estrogen에 의한 자궁내 Eosinophil Chemotaxis의 조절
최순미,이윤호,이창희,원현주 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.10
Objectives: To study the existence of an estradiol-regulated uterine chemotactic factor, testing this with in vivo eosinophilic chemotactic assay by endometrial biopsy specimens from Novak curettage. Methods: We obtained serum and endometrium in 40 control patients with normal menstrual cycles for routine hycecologic check-up. Results: 1) there were no significant difference in age distribution. 2) Mean value of serum estardiol concentrations were according to menstrual date. There were significant difference in mean value of serum estradiol concentration according to menstrual date. Mean value of serum E2 concentration was higher in group 2(MCD #12-#14). 3) Chemotaxis was measured with mean number of migrating eosinophils by endometrial biopsy specimens from Novak curettage, migrating number of eosinophils was greater in group 2(166.5±11.6/HPF) significantly. 4) The magnitude of the chemotactic response was dependent on the dose of estradiol. Conclusions : Uterine chemotactic activity is due to the influx of eosinophils usggest that estradiol stimulates the production of a factor which causes the migration of eosinophils into the uterus.
최순미,김영태,김재욱,조남훈,유용균 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.2
저자들은 최근 난소에서 발생한 악성 말초신경초종양 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A malignant peripheral nerve sheath tumor, apparently arising in the left ovary of a 57 year old woman is described. The patient had no stigmata of von Reclinghausen disease. The tumor was located in the position of the left ovary and had metastasized to ilium. The neural sheath origin of the tumor was confirmed by light mocroscopic finding. After radical excision, she had 6 cycles of adjuvant chemotherapy and still lives without evidence of recurrence.
자궁경관임신에서 Methotrexate 치료 후 소파술을 이용한 보존적 치료의 결과
최호선,변지수,김석모,김병룡 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.4
목적: 본 병원에서 경험한 자궁경관임신의 MTX 치료 후 치료적 소파술을 이용한 보존적 치료방법의 결과를 분석하여 치료효과를 알아보고자 하였다. 연구 대상 및 방법: 1998년 1월부터 1998년 12월까지 전남대학교병원 산부인과에서 자궁경관임신으로 진단된 환자 5명을 대상으로 하였다. 5명 환자 모두에서 MTX[ 1mg/kg/day]와 Citrovorum factor[ 0.1mg/kg/day]를 격일 간격으로 4회 근주하였다. -hCG는 3일 간격으로 측정하였으며, 뚜렷한 감소 경향이 있고 초음파 검사상 크기가 줄어들면 치료적 소파수술을 시행했다. 그러나 증가 하는 경우에는 국소내 직접주입법을 초음파 유도하에 시행하고, 치료적 소파수술을 시행하였다. 결과: 5명의 환자중 2명에서는 1 cycle의 MTX 항암요법에도 불구하고 -hCG 증가소견 있어서 MTX 국소내 직접주입 하였다. 그후 -hCG가 감소하는 소견과 초음파 소견상 종괴 크기 감소소견 관찰할 수 있어서 치료적 소파수술 시행후 정상적인 -hCG로 감소하는 소견 보였다. 나머지 3명은 1cycle의 MTX치료후 치료적 소파수술로 정상적인 -hCG로 감소하는 소견 보였다. 5명 모두 치료적 소파술 후에도 출혈이나 다른 합병증은 없었다. 결론: MTX 치료 1주일 후 치료적 소파술의 시행은 소파술 시행시의 과도한 출혈을 억제 할 수 있으며, MTX 치료 후 수반되는 장기간의 추적검사 기간을 감소시키는 장점이 있어서 이의 임상적 사용도 고려 할 만 하다고 사료된다. 보존적 치료방법인 MTX의 이용은 환자에게 육체적 부담도 적을 뿐만 아니라 부작용도 경미하므로 자궁경관 임신에서 생식기능의 보존여부에 상관없이 우선적으로 선택되어져야 할 것으로 사료된다. OBJECTIVE: To evaluate safety and efficacy of intramuscular methotrexate [MTX] followed by dilation and curettage [D & C] for treatment of cervical ectopic pregnancy. METHODS: Five patients with cervical ectopic pregnancies were treated with four doses of intramuscular MTX [1.0 mg/kg] followed by four doses of intramuscular citrovorum factor [0.1 mg/kg] on alternating days. Patients were followed with measurements of serum -hCG [human chorionic gonadotropin] and sonography every third day during MTX treatment. After MTX therapy, therapeutic curettage was done in one week if there was more than 15% decrease of -hCG and measurements of serum -hCG [human chorionic gonadotropin] and sonography were done every week until the level of serum -hCG was normalized. RESULTS: Three patients showed decreasing titers of serum -hCG after MTX/citrovorum therapy. Two of the five patients showed increasing concentrations of serum -hCG after MTX/citrovorum treatment. After intramniotic injection of MTX, serum -hCG titer was decreased in the cases. one week later, D & C was performed followed by insertion of Foley catheter. All patients did not experience severe bleeding or other untoward effects after D & C. CONCLUSION: These results suggest that MTX/citrovorum therapy followed by D & C is safe and effective when used as primary therapy for cervical ectopic pregnancy.
최순미,이국,이병석,이창희,유용균 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.6
최근저자들은 제태기간 41주로 선천성 기형을 동반하지 않고 양막대에 의한 제대 감돈으로 자궁내 태아 사망이 되었던 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. The amniotic band syndrome(ABS) is the triad of amnion-denuded placnta ;fetal attachment to or entanglement by amniotic remnants ; and fetal deformation, malformation or disruption. Nearly 10% of amniotic bands include umbilical cord strangulation. Cord entanglement may occur before or after other damage to the fetus by amniotic bands and, encountered at near-term pregnancy. Because of the apparent rarity of this condition, the following case is reported. We had experinced a case of intrauterine fetal death at term caused by strangulation of umbilical cord by amniotic band and presented with a brief review of literatures.
최순미,이국,이윤호,박용원,서경,남궁란,유용균 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.1
Management of preterm premature rupture of the membranes(PPROM) represents a clinical dilemma for the obstetrician. Several randomized controlled trials showed that if the membranes had been ruptured, they recommanded immediate delivery for reducing infectious complications, however others recommanded expectant and conservative management for reducing complications related to prematurity. In this study, we compared the neonatal mortality and morbidity between neonates with and without ruptured membranes. 1. The incidence of PPROM was 3.1 percents of total birth. 2. Neonatal death, respiratory distress syndrome, asphyxia, ventilator care, pneumonia, intraventricular hemorrage and urinary tract infection were not different between two groups, however there were significantly statistical differences of hyperbilirubinemia and NICU care. 3. Hperbilirubinemia and NICU care showed significantly statistical differences between two groups, especially after 35 gestational weeks. 4. There were significant increases in ventilator care and NICU care, however no increases were found in other infectious morbidity and respiratory distress syndrome. In conclusion, there was no difference between two groups on infectious morbidity and neonatal death and we may suggest that such findings were resulted from the prophylactic antibiotic therapy.