고양이 위 평활근에서 KCI에 의한 근수축에 대한 Protein Kinase의 조절

심상수,김승록,심혜선,이덕주,한상준,윤신희,조양혁,김명석 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.3

고양이 위 평활근 수축에 대한 Vanadate와 Pervanadate의 효과

심상수,최효봉,심혜선,이덕주,윤신희,한상준,김명석,조양혁 大韓消化器病學會 1999 大韓消化器病學會誌 Vol.33 No.1

유동성 복합레진의 마모저항성에 관한 연구

윤연희,김정욱,이상훈,한세현 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.2

시술시간을 줄이는데 유리한 재료인 유동성 복합레진을 유구치부에 사용하려고 고려할 때 중요한 물성 중 하나는 마모저항성이다. 이 연구의 목적은 유동성 복합레진의 마모저항성을 일반복합레진의 마모저항성을 비교하는 것이다. 실험에 사용된 유동성 복합레진으로 1군에서는 Arabesk flow (VOCO, Germany), 2군에서는 Tetric flow (Vivadent, Liechtenstein), 3군에서는 Aeliteflow (Bisco, U.S.A), 4군에서는 Filtek flow (3M Dental Co, U.S.A)을 사용하였으며 대조군으로 사용한 5군의 복합레진은 Z100 (3M Dental Co, U.S.A)이었다. 시편들(n=10)은 두께 2mm, 지름 5mm의 원통모양으로 제작하여 마모시험 전 37℃의 증류수에서 7일 동안 담가 놓았다. 제1소구치와 레진시편을 MTS 시스템에서 2Hz로 50,000회 접촉, 마모시켰다. 마모시험시 lateral excursion은 0.4mm, 교합력은 2-100N의 조건이었다. 마모시험후 마모된 부피, 최대마모깊이, 재료자체의 표면경도를 측정하였고 마모되지 않은 표면과 마모가 일어난 표면을 주사전자현미경으로 관찰하였으며 다음과 같은 결과를 얻었다. 1. 마모된 부피는 3군에서 가장 적었고 4군에서 가장 많았으며 3군<1군<2군<5군<4군의 순서로 증가하였다. 2. 3군, 1군, 2군, 5군이나 4군에 비해 통계적으로 유의하게 마모부피가 적었다(P<0.05). 그러나, 3군, 1군, 2군 사이에서와 5군, 4군 사이에서는 각각 통계적으로 유의한 차이가 없었다. 3. 최대마모깊이는 1군에서 가장 낮았고, 4군에서 가장 깊었으며 1군<3군<5군<2군<4군의 순서로 증가하였다. 4. 5군의 표면경도는 다른 유동성 복합레진군에 비해 통계적으로 유의하게 높았으나(P<0.05). 마모부피나 최대마모깊이와는 통계적으로 유의한 상관관계를 보이지 않았다. 5. 마모되지 않은 표면과 마모가 일어난 표면을 주사전자현미경으로 관찰한 결과, 유동성 복합레진군과 5군 사이에 마모양상이 다르게 나타나는 것을 볼 수 있었다. When we use the flowable resin on the primary molars for quick handling, one of the most important property is the wear resistance. This study was performed to compare the wear resistance characteristics of four flowable composite resins [Arabesk flow (group 1), Tetric flow (group 2), Aeliteflow (group 3), Filtek flow (group 4)] to that of one control composite resin [Z100 (group 5)]. Specimen discs(n=10), 10mm wide and 2mm thick, were stored in distilled water at 37℃ for 7 days prior to testing. The specimens were subjected to 50,000 strokes at 2Hz on the MTS system. During the test, the following parameters were maintained: the ;atera; excursion at 0.4mm, occlusal force at 2-100N with a force profile in the form of a half sine wave. The measurements of volume loss, depth of wear, and Vicker's hardness number of composite resins, and SEM obserbations of the polished and abraded surfaces were established. One-way ANOVA and Scheffe's multi-ple comparison test were employed to detect statistically significant differences among the flowable composite resin group and the control composite group at P<.05. The following results were obtained: 1. Group 3 showed the least volume loss, while group 4 showed the greatest. The mean volume loss increased in the following order: group 3<group 1<group 2<group 5<group 4. 2. Group 3, group 1, and group 2 showed significantly lesser volume loss compared to group 5 and group 4(p<0.05). However, There was no statistically significant difference among group 3, group 1 and group 2. There was no statistically significant difference between group 5 and group 4. 3. Group 1 showed the shallowest depth of wear, while group 4 showed the deepest. The mean depth of wear increased in the following order: group 1<group 3<group 5<group 2<group 4. 4. Group 5 showed significantly highest hardness value compared to the flowable composite resin groups(p<0.05), but there was no correlation between wear resistance and Vickers hardness number. 5. SEM observation of the unworn and worn surfaces revealed the differences in the wear appearance between the flowable composite resin groups and the control.

Lymphangioma에 의한 거설증을 지닌 환자의 개교합 증례보고 : A CASE REPORT

윤희훈,이상대,김영재,장기택,한세현,이상훈 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

Lymphangioma는 림프관에 나타나는 양성종양으로 림프관의 증식을 특징으로 한다. 이 종양의 대부분은 출생 시에 나타나며 종양의 95%정도가 10세 이전에 나타난다. 구강 내에 발생하는 경우에는 혀에서 가장 호발하며 거설증을 야기한다. 대개 양측성으로 혀의 전방 2/3부위에 나타나며 불규칙한 회색과 핑크빛을 띤 소절형태를 보인다. 본 증례 모두에서 환아들은 출생당시 혀에 lymphangioma를 지니고 태어나 거설증을 보였으며 이로 인해 개교합과 하악과성장 양상을 나타내었다. Lymphangioma에 의한 비정상적인 혀의 비대에 의해 환아의 구강과 두개안면부의 주위조직에 대한 적응 결과로 나타난 소견을 관찰하고 관련문헌을 고찰하여 다소의 지견을 얻었기에 보고하는 바이다. Lymphangioma is a benign tumor of lymphatic vessels. The majority of cases are present at birth and 95% of the tumors aroused before the age of 10 years. Oral lymphangioma may occur at various sites but are most frequent on the anterior two thirds of the tongue, where they often result in macroglossia. The lesions present nodularity with gray and pink projections. In the present cases, all the patients who had the macroglossia combined with lymphangioma showed openbite and mandibular prognathism. The purpose of this paper was to report the dental and craniofacial findings of macroglossia combined with lymphangioma and review the pertinent literature through the cases.

導入種마늘의 主要形質과 生育特性에 關한 硏究 : Allium sativum L.

李敬姬,黃海鎭,吳仲烈,韓相政 대구효성가톨릭대학교 응용과학연구소 1995 응용과학연구논문집 Vol.4 No.-

導入育種의 一環으로 中國産 마늘 가운데서 球의 形質로 보아 優秀하다고 認定되는 上海種과 瀋陽種을 우리나라 代表品種인 義城種(寒地型) 및 濟州種(暖地型)과 함께 溫室과 圃場栽培 實驗으로 이들의 性能을 檢討한 결과를 要約하면 다음과 같다. 1) 上海, 瀋陽 및 濟州種은 無低溫區와 2∼3℃의 20日, 40日 및 60日間 低溫處理區에서 모두 播種後 約 1週日이 經過한 10月 20日 頃부터 萌芽하기 始作하였다. 萌芽期間은 上海種이 19∼22日, 그리고 濟州種이 17∼26日로서 低溫處理期間이 延長됨에 따라 短縮되었으나 瀋陽種은 低溫處理 與否에 關係없이 9∼12日 所要되었다. 2) 寒地型인 義城種은 無低溫區에서 播種後 74日이 經過한 12月 27日에 萌芽하기 始作하였으며, 低溫處理期間이 延長됨에 따라 漸次 빨라져서 60日間 處理區에서는 播種後 13日이 經過한 10月 26日에 萌芽가 始作되었다. 그리고 萌芽期間이 延長됨에 따라 顯著히 短縮되었다. 따라서 上海種과 瀋陽種은 暖地型이라고 認定되었다. 3) 圃場栽培에서 瀋陽種이 다른 品種에 比하여 根重, 球重 및 球當鱗片種이 가장 무거웠고, 球當鱗片數가 많았으며 또한 球高, 球徑 및 莖徑이 커서 品種間 差異가 있었으나 莖徑/球徑比는 供試 4品種 모두 0.2였다. 4) 上海種은 草長, 莖長 및 花梗長이 매우 짧으며 珠芽重은 0.3g로서 가장 가볍고 葉數가 많으며 葉幅이 컸다. 또한 暖地型인 上海, 瀋陽 및 濟州種의 추대기는 5月 12日로서 추대율은 100%였으나 寒地型인 義城種의 추대기는 6月 8日로서 추대율은 30%였다. 5) 供試 4品種의 植物全體의 乾物重은 播種後 135日 經過한 4月 7日부터, 그리고 球의 乾物重은 播種後 149日이 經過한 4月 21日부터 急激히 增加하였는데 이들中 瀋陽種이 가장 旺盛한 增加를 보였고 그 다음이 上海種이였다. 6) 供試 4品種의 줄기의 乾物重은 播種後 135日이 經過한 4월 7日부터 急激히 增加하였는데 이들중 上海種이 가장 旺盛하게 增加하였고 그 다음이 瀋陽種이였다. 그리고 잎의 乾物重은 緩慢하게 增加하였으나 瀋陽種이 가장 무거웠다. 葉面積은 瀋陽種이 가장 넓으며, 早期에 增加하기 始作하고 그 速度도 빨랐다. 7) 暖地型인 瀋陽種은 上海와 濟州種보다 早生으로서 生育이 旺盛하여 球重이 무겁고 燁數가 많으며 葉面積이 넓어서 우리나라 濟州道와 南海岸地帶에서 普通栽培와 冬季施設栽培에 利用할 수 있으리라고 믿어졌다. As a part of introduction breeding, two Chinese garlic cultivars, Shanghai and Shenyang, were cultivated in greenhouse and in field with two typical Korean cultivars, Euisung and Cheju, southern and northern ecotype respectively, and the characters and growth characteristics were investigated. 1. Shanghai, Shenyang and Cheju cultivars treated with low temperature of 2 ~ 3℃ for 20, 40 and 60 days and also the nontreated ones began to sprout from Oct. 20, about one week after planting. Sprouting periods were 19 ~ 22 and 17 ~ 26 days in Shanghai and Cheju cultivar, respectively. These periods were shortened as the low temperature treating periods were extended, but Shanghai cultivar needed 9 ~ 12 days for sprouting regardless of low temperature treatment. 2. A northern ecotype, Euisung cultivar, began to sprout on Dec. 27, 74 days after planting in period was extended, for 20 ~ 66 days, and began to sprout Oct.26, 13 days after planting. From this result, Shanghai and Shenyang cultivars were recognized as a southern ecotypes. 3. In field cultivation, root weight, bulb weight and clove weight per bulb were superior in Shenyang among all the four cultivars and had many cloves per bulb and also showed superior bulb height and blub diameter. These characters represented differences among cultivars, but the ratio of stem diameter to bulb diameter was 0.2 in all four cultivars. 4. Heights of plant, stem and flower stalk were the longest and the bulblet weight, 7.0g, were the heaviest in Shanghai cultivar. In Shenyang cultivar, the flower stalk was very short and the bulblet weight was light, 0.3g, but had many leaves and showed wide leaf width Shanghai, Shenyang and Cheju cultivars, southern ecotype ones, bolted on May 12 and the bolting ration was 100%, but Euisung cultivar, nothern ecotype, bolted on Jun. 8 and the bolting ra-tio was 30%. 5. Dry weight of whole plant and the bulb increased markedly from Apr. 7, 135 days after planting, and from Apr. 21, 149 days after planting, respectively, in all four cultivars, and Shenyang showed the most vigorous increment and Shanghai was next. 6. Stem dry weight increased markedly from Apr. 7, 135 days after planting in all four cultivars; and Shanghai showed the most vigorous increment and Shanghai was next. Leaf dry weight increased gradually and that of Shenyang were the heaviest one. Leaf area of Shenyang cultivar was most broad and grew early and rapidly. 7. Shenyang cultivar, a southern ecotype, grew earlier as compared with Shanghai and Cheju cultivars, and grew vigorously, and the bulb weight was heavy and had many broad leaves. It was considered that these two Chinese cultivars are possible to cultivate in Cheju and south coast districts of the Korean Peninsula by common method and in greenhouse during winter season.

부하순환 하에서 제V급 복합레진 수복물의 미세변연누출에 대한 재접착제의 효과에 관한 연구

윤연희,김영재,김정욱,장기택,이상훈,김종철,한세현 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

저점도의 레진을 복합레진 수복물 위에 도포하는 것은 미세누출방지와 변연 완전성(integrity) 유지를 위한 한 방법이다. 하지만 장기간 관찰하면, 수복물은 저작압에 의한 영향을 받게 되는데, 저점도의 레진으로 수복물 변연부를 재접착(rebonding)하였을 때 저작압에 의한 응력에 견디면서 계속하여 수복물에 긍정적인 영향을 주는지에 대한 연구는 미흡한 실정이다. 본 연구는 부하순환(load cycling) 하에서 제Ⅴ급 수복물의 미세변연누출에 대한 재접착제 (rebonding agent)의 효과를 알아보고자 하였다. 40개의 건전한 소구치의 협면에 제Ⅴ급 와동을 형성하고 제조사의 지시대로 광중합복합레진으로 수복하였다. 20개씩 무작위로 나누어 표면전색을 하지 않는 Ⅰ군과 표면을 산부식 후 재접착한 Ⅱ군으로 설정하였다. 열순환 후 각 군에서 10개씩의 하위군 (A군=No load cycling군, B군=Load cycling군)으로 나누어 이중 B군의 시편에 1 Hz의 속도로 수직력이 4-100까지 100,000회의 부하순환을 가하였다. methylene blue용액에 침윤시켜 변연의 미세누출릉도를 평가하여 다음과 같은 결과를 얻었다. 1. 교합변연에서는 재접착과 무관하게 유의한 차이가 없었다(ⅠA-ⅡA군, ⅠB-ⅡB군) (p>0.05). 2. 치은변연의 경우는 부하순환을 하지 않은 군의 경우 재접착을 한 군(ⅡA군)이 재접착을 하지 않은 군 (ⅠA군)에 비해 더 적은 미세누출결과를 보였다(p<0.05). 3. 치은 변연에서 부하순환을 시행한 군의 경우에는 재접착을 한 군(ⅡB군)과 재접착을 하지 않은 군 (ⅠB군)과 유의차가 없는 비슷한 미세누출의 결과를 보였다(p>0.05). One clinical technique recommended f3r improving marginal integrity is "rebonding" or application of unfilled resins to the surface of composite restoration. But continuously the restorations are affected with occlusal load. There is room for doubt that the rebonding agent has the positive effect on microleakage in spite of the stress generated by the occlusal load. This study determined the effect of rebonding on microleakage of Class Ⅴ resin composite restorations under load cycling. Class Ⅴ cavities were prepared on the buccal surface of 40 sound extracted premolars and restored with a hybrid light-cured resin composite according to manufacturers' directions. They wert randomly divided into two groups consisting of 20 samples a control(group Ⅰ), without surface sealing, and the other group (group Ⅱ) in which margins were etched and rebonded. After thermocycling, each of groups was divided into subgroups (group A, B), and load cycling(total 100,000 cycles with 4-100N load at a rate of 1 Hz) were applied on the group B. Assessment of microleakage utilized methylene blue dye penetration. The following results were obtained : 1. In the occlusal region, no significant difference was noted in the scores regardless of whether or not the rebonding agent was used (group ⅠA-ⅡA, ⅠB-ⅡB) (p>0.05). 2. In the cervical region, the control group with rebonding (group ⅡA) showed the better result than the group without rebonding (group ⅠA) (p<0.05). 3. In the cervical region, the rebonded group with load cycling(group ⅡB) showed similar results to the groupf·ithout rebonding(group ⅠB) and no significant difference was noted(p>0.05).

韓國 家族制度가 社會構造의 變化에 미치는 影響

蔡中默,梁琮懿,沈相潤,韓琫熙,卓鎭煥 全北大學校 法政大學 極東問題硏究所 1974 극동논총 Vol.2 No.-

한국인 주요우울장애 환자에서 혈중 ACTH, Cortisol 농도와 해밀턴 우울 평가 척도의 신체증상 항목과의 상관관계

여혜빈,김린,함병주,심세훈,권영준,정희연,정한용,한상우,이민수,이화영 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:Hypothalamic-Pituitary-Adrenocortical(HPA) system dysregulation plays an important role in the pathophysiology of major depressive disorder. Medically unexplained somatic symptoms comprised the predominant complaints of korean patients with major depressive disorder. It might be related to dysregulation of HPA system and somatic symptoms. The aim of this study was to investigate the association between Hamilton Depression Rating Scale severity and the Plasma Adrenocorticotropic Hormone(ACTH) & Serum Cortisol level in Korean patients with major depressive disorder. Methods:Our study design was prospective. A total 111 hospitalized patients with major depressive disorder (DSM-IV) at Anam Hospital, Korea University Medical Center between Jan 2009 and May 2011 were selected. Hamilton Depression Rating Scale was measured by psychiatrist. Plasma ACTH, Serum Cortisol levels were analyzed at the time of admission. Results:There are significant correlations(p<0.05) between Hamilton Depression Rating Scale of somatic component(HAM-D 11-15 item) and Plasma ACTH and Serum Cortisol level. However, other HAM-D sub items were not significantly correlated with Plasma ACTH and Serum Cortisol level except somatic component. Conclusion:Our Study results suggest that hyperactivity of HPA axis might be correlation with somatic symptoms in korean patients with major depressive disorder.

Controls on KSTAR Superconducting Poloidal Field(PF) Magnets

Sang-hee Hahn,K.H. Kim,J.H. Choi,H.S. Ahn,D.K. Lee,K.R. Park,N.W. Eidietis,J.A. Leuer,M.I. Walker,H.L. Yang,W.C. Kim,Y.K. Oh 한국초전도저온학회 (구 한국초전도저온공학회) 2008 한국초전도저온공학회논문지 Vol.10 No.4

Controls on KSTAR Superconducting Poloidal Field (PF) Magnets

Hahn, Sang-Hee,Kim, K.H.,Choi, J.H.,Ahn, H.S.,Lee, D.K.,Park, K.R.,Eidietis, N.W.,Leuer, J.A.,Walker, M.L.,Yang, H.L.,Kim, W.C.,Oh, Y.K. The Korean Society of Superconductivity and Cryoge 2008 한국초전도저온공학회논문지 Vol.10 No.4

As a part of the plasma control system (PCS) for the first plasma campaign of KSTAR, seven sets of fast feedback control loop for the superconducting poloidal field magnet power supply (PF MPS) have been implemented. A special real-time digital communication interface has been developed for the simultaneous exchanges of the current/voltage data from the 7 sets of 12-thyristor power supplies in a 200 microsecond control cycle. Preliminary power supply tests have been performed before actual cooldown of the device. A $29mH/50m{\Omega}$ solenoid dummy has been fabricated for a series of single power supply tests. Connectivity and response speed of the plasma control system have been verified. By changing hardware cabling, this load was also used to estimate mutual inductance coupling effects of two geometrically adjacent solenoid coils on each power supply. After the cooldown was complete, each pair of the up/down symmetric PF coils has been serially connected and tested as part of the device commissioning process. Bipolar operation and longer pulse attempts have been investigated. The responses of the coils and power supplies corresponding to the plasma magnetic controls in plasma discharges are also analyzed for the future upgrades.