美國의 酪農協同組合에 관한 實證的 硏究

朴鍾洙,閔炳烈 韓國農業政策學會 1991 농업경영정책연구 Vol.18 No.1

정신분열증에서 신경증적 증상의 임상적 의의에 관한 연구

박병관,신석철,강민희,신윤오 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

To investigate the clinical significance of the neurotic symptoms in schizophrenia, the author applied PSE(Present State Examination) on Screening Schedule to 153 schizophrenic patients who were fit for the aim of this study. The patients were divided into two groups to grasp the phenomenological characteristics as the group with neurotic symptoms (100 cases) and the group without neurotic symptoms(53 cases). Among 91 items except neurotic symptoms in PSE, 14 items were selected as significant under X²-test, and tried factor analysis with 14 items using SPSS/PC+. The results of this study were summarized as follows. 1. In the group with neurotic symptoms, 4 factors were extracted as slowness of speech and behavior and blunted affect factor, inappropriate answer and affect factor, delusion factor, and restricted and poverty of speech factor. In the group without neurotic symptoms, 5 factors were extracted as slowness speech and behavior and incoherence factor, inappropriate and poverty speech and self-neglect factor, delusion factor, inappropriate affect factor, and loss of affect factor. In the group of total patients, 4 factor were extracted as restricted and slowness of speech and behavior and blunted affect factor, delusion factor, inappropriate and poverty of speech and inappropriate affect factor, and incoherence factor. 2. In the group with neurotic symptoms, slowness of speech and behavior, inappropriate answer, blunted and inappropriate affect were the major symptoms and inappropriate answer and affect, delusion, restricted and poverty of speech were the minor symptoms. Among these symptoms, slowness restriction, poverty of speech and behavior, inappropriate answer and characteristic blunted affect were characterized by negative symptoms(i.e. defect state) which were frequent in chronic schizophrenia. 3. In the group without neurotic symptoms, slowness of speech and behavior, incoherence, and self-neglect were the major symptoms and inappropriate and poverty of speech, delusion, inappropriate and loss of affect were the minor symptoms. Among these symptoms, slowness and inappropriateness of speech and behavior, and characteristic incoherence and self-neglect were characterized by positive symptoms which were interpreted as less distorted reality than the group with neurotic symptoms in the process of schzophrenia. 4. In the group of total patients, restricted and slowness of speech and behavior, blunted affect and delusion were the major symptoms and inappropriateness, poverty and incoherence of speech, and inappropriate affect were the minor symptoms, which were composed of the major and the minor symptoms of the group with neurotic symptoms and without neurotic symptoms. These symptoms can be seen frequently in the diagnostic criterias and clinical practice and thought to be the result of the major symptoms common in schizophrenia regardless of he presence of neurotic symptoms.

양식 은어의 미포자충 감염예에 대한 병리조직학적 관찰

조병열,강형길,강효주,류갑민,이재영,박남규,허민도 한국어병학회 2003 한국어병학회지 Vol.16 No.1

1998년 9월 말경, 경남 지역의 양식 은어(Plecoglossus altivelis)에서 미포자충증이 발생하였다. 채집 당시, 하루 약 200마리씩의 폐사가 10일째 진행되고 있었으며 약 10%의 누적폐사율을 나타내었다. 병어는 입올림을 하거나 기면 상태에 있었으며, 대부분 체색흑화 및 복부팽만 소견을 보이고 있었다. 아가미, 아가미 뚜껑, 각종 내장, 복강벽 및 생식소에 직경 1~3㎜의 흰색 결절이 다수 형성되어 있었다. 감염 어종, 기생충의 형태 및 xenoma 분포 장기의 다양성에 근거하여 Glugea plecoglossi에 의한 감염증으로 추정되었다. 병리조직학적 검사를 실시한 결과, 광범위한 장기에 걸쳐 xenoma를 형성하고 있었으나 xenoma 인접조직에 변성 변화는 없었다. 아가미 새변, 비장, 두신 및 체신의 조혈영역에 심한 울혈 소견이 인정되었고, 간장, 심근 및 신세뇨관 국소에는 응고 내지 액화괴사 소견이 확인되었다. 따라서, xenoma의 인접조직에 대한 물리화학적인 영향보다는 xenoma형성 장기 및 조직에 야기된 국소 순환장애가 은어의 폐사와 직접적인 관련을 갖는 것으로 사료되었다. On September in 1998, a microsporidian infection was recognized in ayu, Plecoglossus altivelis, farmed on Kyongnam province of South Korea. Cumulative mortality was around 10% in 10 days. Infected fish which were piping for air near the surface of the water or in the asphyxic, lethargic condition revealed darkening of body and abdominal distention. Numerous whitish nodules up to 3㎜ in size were observed throughout most of body organs and tissues including gill, operculum, peritoneal wall and organs. Xenomas were also histologically confirmed in multiple internal organs with the evidences suggesting circulatory disturbance. Based on the morphology of spore and xenoma, and the distribution of xenomas in organs and tissues, this disease was diagnosed to be a microsporidiosis caused by Glugea plecoglossi. The mortality might be deeply related to the local circulatory disturbance by xemonas rather than the mechano-chemical effect of xenomas on adjacent tissues.

Phenazine Methosulfate의 Superoxide Radical 生成作用에 미치는 光線의 影響

李民化,李起榮,梁誠烈,朴昞柱,全鉉權 全南大醫大 1985 전남의대학술지 Vol.22 No.4

瀉白散의 肥滿細胞 嫫介性 炎症性 細胞活性物質 分泌 抑制 效果

이병주,신조영,이시형,홍재의,박병민,이승언 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Ocjective : Sabaeksan has been used for the purpose of prevention and treatment of bronchial asthma and allergic asthma in korea. Methods : To investigate the biological effect of Sabaeksan, the author examined cytotoxicity and inflammatory cytokines secretion with human leukemic mast cell line, HMC-1. HMC-1 was stimulated with phorbol 12-myristate 13-acetate (PMA) and calcium ionophore A23187. Sabaeksan by itself had no effect on viability of HMC-1. Result : The effects of Sabaeksan on the secretion of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-6 from HMC-1 were evaluated with enzyme-linked immunosorbent assay. Sabaeksan (1 mg/㎖) inhibited PMA plus A23187-stimulated TNF-α and IL-6 secretion, by 43.86 ± 5.26%, 56.39 ± 3.65%, respectively. Sabaeksan also inhibited the NF-κB (p50/p65) expression. Conclusion : Taken together, these results suggest that Sabaeksan inhibit the production of inflammatory cytokines in HMC-1 cells through blockade of NF-κB activation.

넙치, Paralichthys olivaceus의 수온 자극 스트레스에 대한 사료첨가제 투여 효과

권문경,박상언,방종득,조병열,이상민,박수일 한국어병학회 2003 한국어병학회지 Vol.16 No.3

본 연구는 넙치의 수온 스트레스에 대한 사료첨가제 (미역 5%, 미역 10%, 어보산 0.5%, 고추냉이 잎 2%, 고추냉이 줄기 2%)의 영향을 혈액학적, 면역학적 측면과 Edwardsiella tanda를 사용하여 질병에 대한 저항성으로서 평가하였다. 혈장의 글루코즈와 콜티졸 농도는 1차 수온 변동 후 대조구에 비하여 미역 5%와 고추냉이잎 2% 첨가구에서 유의적으로 낮게 나타났다(P〈0.05). 1차 수온 변동 후 혈장 라이소자임 활성과 E. tarda의 공격 시험 후 생존율은 미역 5%첨가구에서 대조구에 비하여 유의적으로 높게 나타났다(P〈0.05). 본 실험 결과 미역 5% 첨가 사료 투여는 넙치의 스트레스 상태에서 질병 감염에 대한 저항성을 높일 수 있을 것으로 사료된다. The effect of each dietary supplements (Undaria 5%, Undaria l0%, Obosan 0.5%, Wasabi leaf 2%, Wasabi stem 2%) on the water temperature fluctuation in juvenile olive flounder (Puralichthys olivaceus) was investigated. The response to stress was assessed in terms of effects on haematological and immunological, and resistance against Edwurdsiella tarda infection. Plasma glucose and cortisol levels were significantly lower in 5% undaria and 2% wasabi leaf supplement groups than the controls after the first change of water temperature (P<0.05). The plasma lysozyme activities and the survival rates from E. tarda infection were significantly higher in the 5% undaria supplement groups than the control (P<0.05). These results suggest that the 5% undaria supplement seems to be contributable to the increased disease resistance on olive flounder.

蘇葉이 폐혈관에 미치는 영향

이상훈,박병민,이인,신조영,이시형 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

Folium Perillae has been used in Korea for many centuries as a treatment for various disease. The purpose of the present study is to determine the effect of Folium Perillae on norepinephrine(NE) induced pulmonary artery contraction in rabbit. Rabbit(2 kg, male) were killed by CO2 exposure and a segment (8-10mm) of each rabbit was cut into equal segments and mounted in a tissue bath. Contractile force was measured with force displacement transducers under 2-3 g loading tension. The dose of norepinephrine(NE) which evoked 50% of maximal response (ED50) was obtained from cumulative dose response curves for NE(10-6∼10-3M). Contractions evoked by NE (ED50) were inhibited significantly by Folium Perillae in pulmonary artery. The mean percent inhibition of NE induced contraction was 16.7% (p〈0.05) after 10.0㎎/㎖ Folium Perillae. Propranolol slightly but significantly attenuated the inhibitory effects of Folium Perillae. Following treatment with propranolol, the mean percent inhibition caused by 10.0㎎/㎖ Folium Perillae fell to 16.2% in guinea pig induced by NE contraction. ODQ, methylene blue and L-NNA did not significantly alter the inhibitory effect of Folium Perillae. These results indicate that Folium Perillae can relax NE induced contraction of pulmonary artery, and that this inhibition involves sympathetic effects.

Electric-field control of deterministic spin-orbit torque switching via laterally modulated Rashba effect in Pt/Co/AlO<SUB>x</SUB> structures

Min-Gu Kang,Jong-Guk Choi,Jimin Jeong,Jae Yeol Park,Hyeon-Jong Park,Jong Min Yuk,Kyung-Jin Lee,Byong-Guk Park 한국자기학회 2020 한국자기학회 학술연구발표회 논문개요집 Vol.30 No.2

Clinical results of stereotactic body frame based fractionated radiation therapy for primary or metastatic thoracic tumors

Min Yoon, Sang,Kyung Choi, Eun,Lee, Sang-Wook,Yong Yi, Byong,Do Ahn, Seung,Soo Shin, Seong,Joo Park, Heon,Ssan Kim, Su,Park, Jin-Hong,Yeol Song, Si,Il Park, Charn,Hoon Kim, Jong Taylor Francis 2006 Acta oncologica Vol.45 No.8

<P>The aim of this study was to evaluate the treatment outcomes of stereotactic body radiation therapy for treating primary or metastatic thoracic tumors using a stereotactic body frame. Between January 1998 and February 2004, 101 lesions from 91 patients with thoracic tumors were prospectively reviewed. A dose of 10–12 Gy per fraction was given three to four times over consecutive days to a total dose of 30–48 Gy (median 40 Gy). The overall response rate was 82%, with 20 (22%) complete responses and 55 (60%) partial responses. The one- and two-year local progression free survival rates were 90% and 81%, respectively. The patients who received 48 Gy showed a better local tumor control than those who received less than 48 Gy (Fisher exact test; p = 0.004). No pulmonary complications greater than a RTOG toxicity criteria grade 2 were observed. The experience of stereotactic body frame based radiation therapy appears to be a safe and promising treatment modality for the local management of primary or metastatic lung tumors. The optimal total dose, fractionation schedule and treatment volume need to be determined after a further follow-up of these results.</P>

Frequency control of a spin-torque oscillator using magnetostrictive anisotropy

Park, Min Gyu Albert,Baek, Seung-heon Chris,Park, Byong-Guk,Lee, Seok-Hee American Institute of Physics 2016 Applied Physics Letters Vol.108 No.2