최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

韓·中 企業會計制度의 比較硏究 : 중국기업회계제도의 특성을 중심으로

吳鍾錫 대불대학교 1998 論文集 Vol.4 No.1

The reforms launched by Deng Xiaoping two decades ago had a great impact on the Chinese economic system and the accounting system has also changed very rapidly in this period. This paper aims to compare Chinese accounting standards with Korean and provide a finantial analysis framework for Korean investers to China. In accordance with "The Accounting Law of the People's Republic of China", the Chinese accounting standards are formulated to meet the needs of a socialist market economy, to standardize accounting practice and to ensure the quality of accounting information. Since 1990, Korean companies have invested in China for their business globalization, but are face with many problems such as tax, profit return and joint-venture contract dispute etc. Therefore, we need to understand Chinese accounting and its practice but there are many differences in terminology and classification of accounts with its Chinese characteristics. In conclusion, the harmonization of accounting standards in Korea and China will contribute to the Korea-Chinese economic cooperations and the development of international accounting standards.

현행 고등학교 화학 교과서 비교 연구

오제직,최석남,이종길 공주대학교 사범대학 과학교육연구소 1994 과학교육연구 Vol.25 No.1

This paper aims to help the teachers select the textbook and provide them with the basic teaching materials as an ideal model by analyzing the organization (its element and appropriateness), volume amount, experiment matter, and the contents of the highschool chemistry textbooks, which have been revised in accordance with the 5th amended curriculum. The results of the analogy are as follow 1. Organization (its element and appropriateness) : Though having some distincitive characteristics, all the textbooks have almost the same introduction, development, summary, and further study, which are appropriate for the textbook model. 2. The volume amount: All the textbooks have almost the same frame, but s a big difference in such things as the number of pages, of pictures and charts, of Gothic terminology, and relative importance of each chapter. And all the materials such as pictures and photos are black-and-white, which we think are less helpful to the students` study. 3. The experiment matter: There`s a geat difference in the number, kinds, ratio contents and subject of experiment in each chapter. And there are some distinctive characteristics in the type, level, method, and investigative skills of the experiments. 4. The contents : There are considerable differences in the additional and reduced sections. Therefore, which book is selected is very important, and the teachers should not skip any class-work.

심리적 임파워먼트의 선행요인과 결과요인에 관한 연구

오종석,김종관,이용탁 釜山大學校 商科大學 2002 釜山商大論集 Vol.73 No.-

The purpose of this research is to examine the antecedents and outcomes of psychological empowerment. Focusing on the psychological experience of empowerment, we first examined the relationship between antecedents and the four dimensions(meaning, competence, self-determination, impact) of psychological empowerment. Second, we examined the impact of psychological empowerment on the job satisfaction and job related strain. This empirical results are as follows. First, individuals who perceive that have a high degree of self-esteem, internal of locus of control report a high level of psychological empowerment. And individuals who perceive that have a high degree of role ambiguity in their work report a lower level of psychological empowerment. Second, individuals who perceive that have a high degree of sociopolitical support, access to information, access to resources, participate work climate in their organization report a high level of psychological determinant, impact dimensions in psychological empowerment. But, competence is not significantly influence on the job satisfaction. Finally, all dimensions of psychological empowerment are not significantly impact on the job related strain. As the results, psychological empowerment is associated with in the feeling of job satisfaction, and is recognized as one means by which organizations can effectively manage management innovations.

Streptococcus oralis 의 인공치태 억제효과에 대한 연구

오종석,정성수,양규호,김선미 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1

이 연구는 치아우식증이 주요 원인균인 Streptococcus mutans의 치태형성과 증식에 대한 Streptococcus oralis의 영향을 조사하고자 하였다. 이를 위해 S.mutans와 S.oralis 혼합 배양후 형성된 치태 무게와 생균수를 측정비교하였다. 또한 치태형성과 생균수에 영향을 미치는 요소들에 대해 조사하여 다음과 같은 결과를 얻었다. 1. S.mutans와 S.oralis의 혼합배양시 S.mutans 단독배양에 비해 치태무게와 생균수가 감소되었다. 2. S.mutans 단독배양에 10 mM의 표도당을 첨가한 군은 첨가하지 않은 군보다 치태무게가 증가되었으나,S.mutans와 S.oralis의 혼합배양에 10 mM의 포도당을 첨가한 군은 첨가하지 않은 군과 차이가 없었다. 3. S.mutans 단독배양에 10 mM S.mutans와 S.oralis 10 mM의 과당을 첨가한 군도 첨가하지 않은 군보다 치태무게가 증가되었다. 4. S.mutans와 S.oralis의 혼합농도를 달리하여 배양했을때 S.oralis의 혼합농도가 높아질수록 치태무게와 생균수는 감소되었다. 5. 배양기산(6,9,12,15시간)에 따른 치태무게와 생균수는 S.mutans단독배양에 비해 S.mutans와 S.oralis혼합배양시 배양 12시간 이후 급격히 감소되었다. 6. S.mutans와 S.oralis의 혼합배양에 H₂O₂를 소비하는 Staphylococcus epidermidis를 첨가한 군은 첨가히자 않은 군보다 치태무게와 생균수가 증가되었다. 이상의 결과로 S.oralis는 S.mutans와 혼합배양시 S.mutans의 증식과 인공치태의 생성을 억제함을 알 수 있었고, 이는 S.oralis가 H₂O₂를 분비함으로써 얻어진 결과임이 시사되었다. This study was performed to evaluate the effect of Streptococcus oralis on the formation of artificial plaque and the replication of Streptococcus mutans.S.mutans was incubated alone and in the combination with S.oralis in the beaker with wires. The produced plaque weight and the viable cells of S.mutans were compared between those cultures. Various factors were studied about the effect on the formation of plaque and the replication of S.mutans. Followings are the results. 1. Lower amount of plaque was produced and fewer cells of S. mutans were replicated at the mixed culture of S. mutans and S. oralis than S. mutans alone. 2. When 10 mM glucose was added, the plaque weight was increased in the culture of S. mutans alone. But in the mixed culture of S. mutans and S. oralis, the plaque weight was not increased when 10mM of glucose was added. 3. When 10 mM fructose was added, the plaque weight was increased in culture of S. mutans alone or combined S. mutans and S. oralis. 4. In the mixed culture of S.mutans and S. oralis with different concentration, the more S.oralis exist, the less plaque and the fewer viable cells of S. mutans were observed. 5. The plaque weight and the viable cells of S.mutans were more decreased in the mixed culture of S. mutans and S. oralis than S. mutans alone after 12 hours. 6. When Staphylococcus epidermidis consuming hydrogen peroxide was added to the mixed culture of S. mutans and S. oralis, the plaque weight and the viable cells of S. mutans were increased. These results indicate that S. oralis inhibited the formation of plaque and the replication of S. mutans,and this may result from the formation of hydrogen peroxide by S. oralis.

유산구균 1370의 수용성 글루캔 형성에 영향을 미치는 인자

오인근,양규호,정진,오종석 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

Streptococcus mutans가 치태를 형성할 때, 유산구균 1370(Lactococcus lactis 1370)이 생산하는 수용성 글루캔이 영향을 미친다. 본 연구에서는 여러 인자에 의한 수용성 글루캔 형성 정도를 유산구균 1370 배양 상청액의 흡광도로 측정하여 다음과 같은 결과를 얻었다. 1. 5% 자당이 첨가된 M17 broth에서 유산구균 1370 배양 상청액의 흡광도는 높고 Streptococcus mutans 배양 상청액의 흡광도는 낮았으나, 통계학적인 유의성은 없었다. 2. M17 broth에 10% 자당을 첨가하여 유산구균 1370을 배양할시 배양 상청액의 흡광도는 첨가하지 않을 때보다 높았다(p〈0.05). 배지 pH가 5에서보다 7에서 배양 상청액의 흡광도가 더 높았다(p〈0.05). 3. 32℃, 37℃, 42℃중 37℃에서 배양시 배양 상청액의 흡광도가 가장 높았으나 통계학적인 유의성이 없었고, 호기성 배양시보다 혐기성 배양시 배양 상청액의 흡광도가 더 높았다(p〈0.05). 4. 배지의 CaCl₂농도가 1.0mM에서 (p〈0.05), KCl 농도가 2.5mM에서 (p〈0.05) 배양 상청액의 흡광도가 높았다. 5. M17 broth에 5% 자당을 첨가한 배지에 유산구균 1370을 접종하여 배양한 배양 상청액의 배지를 1:3으로 가한 비커와이어 검사에서 Streptococcus mutans에 의하여 형성된 인공치태 무게는 5.6mg으로 5% 자당을 첨가하지 않을 때의 103.0mg에 비교하여 현저히 감소하였다 (p〈0.05). 이상의 결과를 요약하면 유산구균 1370에 의한 수용성 글루캔의 형성은 자당이 함유된 배지나 세균 증식이 잘 되는 조건에서 증가하였으며, 수용성 글루캔이 Streptococcus mutans에 의한 인공치태 형성을 억제하였다.

유산구균 1370의 수용성 글루캔 형성에 영향을 미치는 인자

오인근,양규호,오종석 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

The water-soluble glucan prodeced by Lactococcus lactis 1370 affects the formation of dental plaque by Streptococcus mutans. In this study the factors affecting the formation of water-soluble glucan were assessed as the optical density of culture supernatant of Lactococcus lactis 1370 in the spectrophotometer. 1. The optical density of culture supernatant was high when Lactococcus lactis 1370 was cultured in M17 broth with 5% sucrose, while being low in culture supernatant of Streptococcus mutans. 2. The optical density of culture supernatant was higher when Lactococcus lactis 1370 was cultured in M17 broth with 10% sucrose than when being cultured without sucrose (p<0.05), and was higher at pH 7 than pH 5 (p<0.05). 3. The optical density of culture supernatant was the highest at 37℃ among 32℃, 37℃ and 42℃, and was higher in the anaerobic incubator than in the aerobic incubator (p<0.05). 4. The optical density of culture supernatant was the highest in the media containing 1.0mM CaCl2 (p<0.05), 2.5mM KCl (p<0.05), and 1.6 mM MgCl2. 5. When Streptococcus mutans was cultured in the media containing a quarter culture supernatant of Lactococcus lactis 1370 grown in M17 broth, the mean weight of produced artificial plaque was 103.0 mg on the wire, whereas being significantly reduced to 5.6mg in the media containing a quarter culture supernatant of Lactococcus lactis 1370 grown in M17 broth containing 5% sucrose (p<0.05). These results indicate that the water-soluble glucan is more formed by Lactococcus lactis 1370 in the media containing sucrose or under the adequate conditions for the growth of bacteria, and inhibits the formation of artificial plaque by Streptococcus mutans.

해조류에서 추출한 SCH-T3의 elastase 억제

오경석,박영립,이종석,황규왕,염윤기 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & Objective: Upon UV irradiation of skin, matrix metalloproteinases are induced and then degrade collagen and elastin which provide the structural integrity of skin. The purpose of this study is to investigate the inhibition of elastase by SCH-T3 extracted from marine plants. Method: From gathered seaweeds, which are Laminariacea and Alariaceae in Phaeophyta, In Korea water, 21 materials were extracted. To determine the optimal condition for the extraction of SCH-T3, the yields of SCH-T3 was measured compared at various solvents, concentrations, and extraction time. Finally, the inhibitory effect of SCH-T3 on elastase was measured under various conentrations of SCH-T3. Results: Among 21 extracts, SCH-T3 had excellent elastase inhibitory effect. The yields of SCH-T3 was highest with the use of 60% and 70% ethanol as sovents, at 12 hours extraction, and with increasing temperature. Conclusion: These results suggest that SCH-T3, extracted from marine plants, has an inhibitory effect on elastase in vitro and may be used in prevention and treatment of photoaging in the future.

신이식에서 이식신의 생존분석

오선미,김종학,황평주,구영선,강민규,나기량,김종섭,김성숙,이강욱,신영태,설종구,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To investigate the prognostic factors for the survival of transplanted kidney in patients with end-stage renal failure, 59 cases of renal transplantation from September 1986 to Feburary 1997 in Chungnam National University Hospital were analyzed retrospectively. The results were as follows: 1)The mean age of recipients was 33.8 years and that of doners was 38.9 years. The male to female ratio of recipients was 2.5:1, and that of donors was 1.03:1 2) Living related donore(LRD) were 79.6% and living non-related donors were 20.3%. The HLA-identical donors(ID) in LRD were 18.7% and HLA-haploidentical donors(HID) were 61.0%. In living non-related donors(LNRD), mean matched HLA-AB antigens were 1.56 and mean matched HLA-DR antigens were 0.56. 3) The average 5-year patient survival fate was 94%, and average 5-year graft survival rate was 70%. The 5-year graft survival fate of HLA-ID was 100%, and those HLA-HID and LNR were 70% and 36% respectively. 4) Total 33 episodes of acute rejection were found in 45.8% of transplanted patients. The number of acute rejection episode did not show significant difference between LRD and LNRD(P > 0.05). There was no significant difference in MLC between two groups(p > 0.05). 5) In comparison between the 18 patients who lost their graft function in 5 years and 17 patients who are maintaining graft function for more than 5 years, MLC was significantly lower in patients with functioning graft than of patients with non-functioning graft (p < 0.05). The number of rejection episode was also lower in patients with functioning graft than that of the patients with non-functioning graft(p < 0.05). However, there were no significant difference in recepient and donor age and history of pre-transplantation donor specific transfusion between two groups. With the results above, we can speculate that adequate donor selection according to good matched HLA typing and low MLC is very important for graft survival in renal transplantation. Prevention and treatment of acute rejection in renal transplantation is also na important factor for graft survival.