전신마취 후 발생한 악성고열증 환자의 치료 경험

이근무,정승환,이정한,정순호,최영균,김영재,신치만,박주열,이영민 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Malignant hyperthermia is the disorder of calcium regulation within skeletal muscle associated predominantly with anesthesia. It is triggered by volatile anesthetics and depolarizing neuromuscular blocking agents. We experienced a case of malignant hyperthermia. 50 years old female patient was transferred to our emergency room that she was developed tachyarrhythmia and high fever. She was taken arthroscopic examination under the general anesthesia with enflurane and succinylcholine. We suspected malignant hyperthermia and promptly treated her with dantrolene sodium. She was developed disseminated intravascular coagulopathy and acute renal failure then we were intensive care to her. She was discharged without sequela. We experienced successful management of malignant hyperthermia.

복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교

김효중;어전영;어근무;어정한;엄세훈;조광래;김명훈 인제대학교 2011 仁濟醫學 Vol.32 No.-

Objectives : We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy. Methods and Materials : Eighty patients who received laparoscopic colectomy were randomly divided into two groups: R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours. Results : The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours: 20% in group R, 17.5% in group 0, at postoperative 24 hours; 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage. Conclusion : Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

Rocuronium의 애별투여방법이 모지내전근의 이완에 미치는 영향

최영균,김승수,이원진,조광래,이상은,김영환,임세훈,이정한,이근무,정순호,김영재,신치만 인제대학교 2009 仁濟醫學 Vol.30 No.-

Objective : There are controversies in pnmmg technique of rocuronium whether it can or can't shorten the onset time. We want to compare the effects of two different priming doses and intervals of rocuronium. Materials and Methods : After giving propofol, 50 patients were randomly assigned to 5 groups. Group I received a placebo, followed 3 min later by rocuronium 0.6 mg/kg. Priming doses and intervals of Group II, Ill, N, V were 0.06 rng/kg and 2 min, 0.12 mg/kg and 2 min, 0.06 rug/kg and 3 min, 0.12 mg/kg and 3 min, respectively. Total dose of rocuronium was 0.6mg/kg. Train of four (TOF) count or ratio and 1st twitch height of TOF (T1) were monitored with 15 secondsintervals. TOF ratio of each groups just before bolus injection, duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were compared. Results : Duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were decreased in priming groups compared to Group 1 (P < 0.01) In group V, significant depression of TOF ratio just before bolus injection was seen (P < 0.05). Conclusion : Priming technique with rocuronium is effective method to shorten the onset of neuromuscular block. But priming dose of rocuronium itself could cause hypoxia and aspiration in awake patients and should be used carefully. Priming dose of rocuronium 0.06 mg/kg and 2 minutes interval maybe relatively safe method.

고선량 방사선 조사후 치아수복재의 특성변화

이용근,이건일,이성재,박수아,허정무 원광대학교 생체재료·매식연구소 1996 원광생체재료·매식 Vol.5 No.2

To investigate the effect of high dose irradiation on the Vickers hardness number(VHN), color change and wear rate of dental filling materials, esthetic filling material specimens were studied. Six kinds of composite resins and two kinds of glass ionomers(GI) were used. One(CLF) was chemically cured composite resin, and five(HCX, HPL, PHB, POF, PRT and RZI) were light cured composite resins. One(FJT) of GI was chemically cured GI and one(FLC) was light cured GI. The filling material specimens were made according to the manufacture's instructions and were finally polished with Microcloth(Buehler). Half of the specimens were irradiated with 100 Gy radiation using a linear accelerator(Mitsubishi, 6 MV). VHN and CIELAB color were measured before and after irradiation, and wear test were performed for nonirradiated specimens by brushing with toothpaste, From the experiment , the following results were obtained. 1. The CIELAB color difference was significantly different depending on the material(p<0.01), and FLC showed the highest color difference (CIELAB ΔE) of 9.452 and CLF showed the lowest value of 3.642. 2. The VHNs of nonirradiated specimens were 12.22∼73.58 and those of irradiated specimens were 25.53∼84.53. The VHNs of irradiated specimens were significantly higher than those of nonirradiated specimens(p<0.05) except RZI, FJT and FLC. 3. The wear rate of irradiated specimens of RZI, FLC were significantly lower than those of nonirradiated specimens(p<0.05). 4. The color difference after brushing of irradiated specimens were higher than those of nonirradiated specimens except CLF.

내분비기관으로서의 심방의 형태학적 특징에 관한 연구 - Ⅱ. 흰쥐의 심방 내강 및 내표면 구조

이무삼,두홍서,고병문,강경진,정우송,박병건,이창현 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2

췌장암 환자에서 알코올 내장신경 신경파괴블럭 후 발생한 간염

이상은,최석환,김영환,임세훈,이정한,이근무,정순호,최영균,김영재,신치만 인제대학교 2008 仁濟醫學 Vol.29 No.-

Splanchnic neurolytic block(SNB) with alcohol improves the management of pancreatic cancer pain. Adverse effects of alcohol SNB which include regional pain, hypotension, diarrhea, and acute alcohol intoxication are common, but acute hepatitis caused by alcohol neurolytic block is rare. A 63-year-old patient with pancreatic head cancer and liver metastasis had complete pain relief after both retrocrural tansdiscal SNB with 100% alcohol 10 ml. But, 1 day later, liver function test showed a high elevation in the aspartate aminotransferase (AST, 2182 IU/L) and alanine aminotransferase (ALT, 1807 IU/L). The patient had slight jaundice, general weakness, chilling, nausea and vomiting after SNB. Both AST and ALT decreased to 46 and 119 IU/L within 10 days with only supportive therapy. But, 19 days later, the patient died due to pneumonia. Our case illustrates the importance of clinical surveillance especially in patient with hepatic disease after alcohol SNB.

방사선 치료 중인 암환자의 정신병리, 자아존중감 및 삶의 질

정찬영,양종철,신일선,최영,윤진상,이무석,이형영,나병식 한국정신신체의학회 2002 정신신체의학 Vol.10 No.2

有機化合物의 放射線 分解에 關한 硏究 : (第 2 報) 空氣포화시킨 CH₃OH과 CH₃OH-H₂O混合溶液의 放射線 分解 Radiolysis of CH₃OH and CH₃OH-H₂O Mixture Solution Saturated with Air

李富永,鄭泰明,趙武濟 慶尙大學校 1972 論文集 Vol.11 No.-

純粹 메탄올과 메탄올-물 混合溶液에 空氣를 飽和시켜 Co??-γ線을 照射하여 H₂O₂, HCHO을 測定하였다. 本 實驗에서 얻어진 G값과 眞空中의 값을 比較검토하고 이를 토대로 Scavenger의 影響을 照射하였다. Yields of gydrogen peroxide and formaldehyde by Co??-gamma radiolysis of pure methanol-water mixture solution saturated with air have been investigated at room temperature. The G-values obtained by the present study and degassed mixture solution is compared and the effect of scavenger is discussed, on the basis of the observed date.

植物油의 불감화물 利用에 關한 硏究 : 第1報 Sterol과 Tocopherol의 定量 Quantitative Analysis of the Free Sterol and Tocopherol

鄭泰明,李富永,趙武濟 慶尙大學校 1972 論文集 Vol.11 No.-

米糠油, 大豆油, 참깨油, 들깨油, 산초 및 菜種油의 불감화물중에 存在하는 free sterol을 column chromatography法과 T.L.C法에 의해 分溜 定量하였고 total tocopherol에 對해서는 Emmeri-Engel法에 의해 定量하였다. 1. Free steol을 용출할 때는 n-hexane-20% benzenedyddor에서만 용출됨을 확인하였다. 2. 이들 植物油의 不??化物中에 存在한 free sterol와 total tocopherol의 含量은 다음과 같다. Free Sterol(㎍/g) Total Tocopherol(㎍/g) 米糠油 1300 490 大豆油 1500 565 참깨油 773 425 들깨油 516 635 산초油 520 740 菜種油 640 470 Free sterols contained in unsaponifiable matters of vegetable oils such as, rice bran oil, soybean oil, sesame oil, japanes pepe oil, rape seed oil. and perilla oil are determined by the column chromatographic and thin layer chromato raphic methods. And also total tocopherols are investigated by Emmerie-Engel Procedure 1. For the elution of free sterol, it is only eluted when the n-hexane-20% benzene solution were added on the column paked silica gel. 2. Quantities of free sterol and total tocopherol contained in unsaponifiable matters of these oils are as follow, Free Sterol Total Tocopherol (㎍/g) (㎍/g) Rice Bran Oil 1300 490 Soybean Oil 1500 565 Sesame Oil 773 425 Japanes Peper Oil 516 635 Rape Seed Oil 520 740 Perilla Oil 640 470

선속이 선회권에 미치는 영향에 관한 연구

李根茂,吳政錫 弘益大學校 産業技術硏究所 2005 産業技術 Vol.15 No.-

The turning circle of a ship is the path followed by her center of gravity in making a turn of 360° degree or more with helm at constant angle. But generally it means her path traced at full angle of the rudder. For the ordinary ship the bow will be inside and the stern outside this circle. It has been usually understood that the turning circle is not essentially affected by ship's speed at Froude numbers less than about 0.3. However, it is recently reported that the speed provide considerable effects upon the turning circle on piloting many ships actually at sea. In this paper, the author analyzed what effects the speed could provide on the turning circle theoretically from the viewpoint of ship motions and examined how the alteration of the speed at Froude no. under 0.30 affect the turning circle actually, through experiments of actual ships of a small and large size.