Se/CS₂용액으로 처리한 n-GaAs 표면의 Photoreflectance 특성에 관한 연구

장광수,김인수,배인호,한병국,이정열 嶺南大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.17 No.-

The surface of of n-GaAs(100) was treated using 1.5㎎/100ml solution of Se/CS₂. The passivation of the surface of this sample was investigated by photoreflectance(PR) experiment. After the surface treatment, the samples were annealed between 300 to 700 ℃ in a N₂atmosphere for 10 min. From the obtained Franz-Keldysh oscillations, we have evaluated the surface electric field(E?) and built-in voltage(V??). The density of surface states(Q??) and surface Fermi level(E??) of n-GaAs treated with CS₂and Se/CS₂solution were determined 1.78 ×10??㎝?? , 1.81×10?㎝? and 0.734 eV, 0.737 eV, respectively. After annealed at 600 ℃, These values were about 45% and 13% smaller than those in unannealed samples. It has found that the passivation of surface occured when the surface of the sample had been treated with Se/CS₂ solution and annealed from 400 to 600 ℃. This is ascribed to effects due to activation of elemental Se on the surface.

상추(Lactuca sativa L.)의 ACAT 억제 Diterpenoid, Phytol : 식용 식물자원으로부터 활성물질의 탐색 Development of Biologically Active Compound from Edible Plant Sources

장태오,방면호,송명종,홍윤희,김지영,정대균,배동근,권병목,김영국,이현선,김인호,백남인 한국농화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.1

Transvenous proximal closure of large congenital coronary arteriovenous fistula using the single Amplatzer vascular plug in a 3-year-old girl

Jang, Hae In,Choi, Young Earl,Cho, Hwa Jin,Cho, Young Kuk,Ma, Jae Sook The Korean Pediatric Society 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.2

Congenital coronary arteriovenous fistulas (CCAFs) are rare coronary artery abnormalities in which blood is shunted into a cardiac chamber or great vessel. If the fistula itself is large and tortuous, it is generally recommended to occlude the fistula to prevent several complications. In approaches of transcatheter occlusion, the transvenous approach is preferred over the transarterial approach. The transvenous approach would enable the cannulation of a relatively larger catheter or sheath without potential damage to the femoral vessels or normal coronary arteries, which can occur in the transarterial approach. The transvenous approach may also minimize the blind pouch after releasing the devices. Herein, we report the success of transvenous proximal closure of a CCAF using an Amplatzer vascular plug (AVP) in a 3-year-old patient with cardiomegaly. Complete occlusion was achieved by a single AVP and thrombus formation of the distal aneurysmal portion of the fistula. We suggest that this strategy of closing the proximal end with a dilated fistula using a single AVP by the transvenous approach may be a good option in treating CCAFs in a young child.

기관지 천식 환자에서 플루티카손 프로피오네이트의 치료효과

장안수,최인선,나현주,박석채,김영철,국훈 최신의학사 1997 最新醫學 Vol.40 No.6

절제 가능한 간세포암에서 수술 전 경동맥화학색전술의 효과

김인숙 ( In Sook Kim ),임영석 ( Young Suk Lim ),윤현기 ( Hyun Ki Yoon ),성규보 ( Kyu Bo Sung ),장명국 ( Myoung Kuk Jang ),최원범 ( Won Beom Choi ),김성훈 ( Sung Hoon Kim ),이한주 ( Han Chu Lee ),정영화 ( Young Hwa Chung ),이영상 ( 대한내과학회 2005 대한내과학회지 Vol.69 No.6

Background : Although hepatic resection (HR) is the mainstay for the treatment of hepatocellular carcinoma (HCC), high recurrence rate (>60%) is major serious problem. Thus preoperative transarterial chemoembolization (TACE) has been proposed as a neoadjuvant treatment before HR. However, the effect of preoperative TACE in preventing recurrence for initially resectable HCC remains controversial. This study aims at assessing the role of preoperative TACE on the early and long-term outcome following resection of HCC. Methods : Retrospective randomized analysis was performed. A total of 366 patients who had HR for HCC between January 1995 and December 2000, were included, 132 patients underwent preoperative TACE (TACE plus HR) and 234 patients did not (HR). Statistically no baseline characteristic difference in two groups. Results : HR group was significantly higher than TACE plus HR group in disease-free survival rate and overall survival rate (p<0.001, p<0.01). In subgroup analysis, the disease-free survival rate of HR group was higher than TACE plus HR group in UICC T1-2 and UICC T3 (p<0.01 for both), whereas the difference in overall survival rate was significant only in UICC T3 (p<0.01). Those who achieved tumor necrosis of more than 95% by preoperative TACE showed comparable overall survival rate with HR group, while it was significantly lower in patients who demonstrated tumor necrosis of less than 95% (p<0.001). Conclusions : Preoperative TACE for initially resectable HCC may promote early and late tumor recurrence and reduces overall survival rate after surgery particularly in patients with advanced-stage tumors.(Korean J Med 69:614-621, 2005)

최근 10년간 대구,경북 지역 성인에서 바이러스성 간염 표지자 양성률의 변화양상

이경인 ( Kyung In Lee ),박경식 ( Kyung Sik Park ),서혜진 ( Hye Jin Seo ),김태열 ( Tae Yul Kim ),김은수 ( Eun Soo Kim ),장병국 ( Byoung Kuk Jang ),정우진 ( Woo Jin Chung ),조광범 ( Kwang Bum Cho ),황재석 ( Jae Seok Hwang ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.2

Background/Aims: There have been only few studies on the population-adjusted seroprevalence of HBV and HCV and on the change of them for more than 10 years in Korea. Therefore, this study was performed to evaluate them at a single health center in Daegu and Gyeongbuk province considering the population composition ratio. Methods: We analyzed the seromarkers of HBV and HCV of 6,237 randomly sampled adults who had received health screening at the health promotion center in Dongsan hospital during the periods from year 1997 to 1999 (Period A) and from 2007 to 2009 (Period B). Results: The seroprevalences of HBsAg, anti-HBs, anti-HBc and anti-HCV were 4.8%, 70.2%, 47.4%, and 0.5%, respectively. There is no difference in the seroprevalence of HBsAg between period A and B. However, downward tendency of prevalence through A to B from 6.8% to 4.5% could be found in 40s, and upward tendency from 4.7% to 6.8% in 50s. As for the seroprevalence of anti-HCV, although there was no difference through A to B, for 50s, it decreasd from 2.0% to 0.3% (p=0.007). However, for 60s, it increased as much as decreasd for 50s. Conclusions: The seroprevalence of HBsAg in Daegu/Gyeongbuk province was 4.8% and showed no difference through the time period of 10 years. The seroprevalence of anti-HCV was 0.5% and also showed no difference through the time periods. (Korean J Gastroenterol 2011;58:82-87)

Heart and Brain Interaction of Psychiatric Illness: A Review Focused on Heart Rate Variability, Cognitive Function, and Quantitative Electroencephalography

Wookyoung Jung,Kuk-In Jang,Seung-Hwan Lee 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.4

Heart rate variability (HRV) reflects beat-to-beat variability in the heart rate due to the dynamic interplay of the sympathetic and parasympathetic nervous systems. HRV is considered an index of the functional status of the autonomic nervous system. A decrease in HRV is thus observed in individuals with autonomic dysfunction. Abnormal HRV has been reported in a range of mental disorders. In this review, we give an overview of HRV in patients with major depressive disorder (MDD), schizophrenia, and posttraumatic stress disorder (PTSD), one of whose core symptoms is cognitive dysfunction. The association between HRV and cognitive function is highlighted in this review. This review consists of three main sections. In the first section, we examine how HRV in patients with MDD, schizophrenia, and PTSD is characterized, and how it is different when compared to that in healthy controls. In the second section, beyond the heart itself, we discuss the intimate connection between the heart and the brain, focusing on how HRV interacts with quantitative electroencephalography (qEEG) in the context of physiological changes in the sleep cycle. Lastly, we finish the review with the examination of the association between HRV and cognitive function. The overall findings indicate that the reduction in HRV is one of main manifestations in MDD, schizophrenia, and PTSD, and also more generally HRV is closely linked to the change in qEEG and also to individual differences in cognitive performance.

Growth Promotion Effects of Plant Extracts on Various Leafy Vegetable Crops

Se Ji Jang,Yong In Kuk 한국원예학회 2019 원예과학기술지 Vol.37 No.3

Though the mechanisms are not yet fully understood, the macro- and micro-nutrients, amino acids, and hormone-like growth substances present in plants (whole plants and their extracts) may lead to biostimulatory activities when applied to crops. This study was conducted to determine the growth promotion effects on lettuce (Lactuca sativa L.) of plant extracts obtained by different extraction methods (water, boiling water, fermentation, and ethanol) from 31 agricultural materials. We also determined the growth promotion effects of three other leguminous crop extracts on lettuce. In total, these 31 different agricultural materials produced 82 different extracts. The most effective extracts were water and boiled water extracts of Chinese chive (Allium tuberosum), water extracts of soybean leaves (cvs. Daewon and Haepum), and water, fermentation, and ethanol extracts of soybean stems (cv. Daewon). These induced a 31 - 45% increase in shoot fresh weight of lettuce compared with control plants. Chinese chive, soybean leaf, and soybean stem extracts had a greater impact on shoot fresh weight of lettuce when applied at 20 days after seeding (DAS) than when applied at 30 and 40 DAS. In addition, when extracts from Chinese chive and soybean leaf and stem were used, the shoot fresh weight of lettuce was higher at 7 days after treatment (DAT) than at 14 and 21 DAT. The shoot fresh weight of lettuce was 13 - 15% higher when the selected extracts were applied twice instead of once. Moreover, the growth promotion effects of the selected plant extracts were also observed in endive and broccoli, but not in pak choi and kale. Additionally, the growth promotion of lettuce was higher in response to soybean leaf and stem extracts than extracts of other leguminous crops (cowpea, mung bean, and red bean). The selected extracts showed higher growth promotion effects on lettuce than those of urea and a commercial extract. Overall, the results indicate that the selected plant extracts can be used for growth promotion in organic cultivation of various crops.

Electroencephalographic Correlates of Suicidal Ideation in the Theta Band

Lee, Sang Min,Jang, Kuk-In,Chae, Jeong-Ho SAGE Publications 2017 Clinical EEG and neuroscience Vol.48 No.5

<P>Previous studies have indicated that the abnormalities of brain activity are associated with suicidal behavior. However, few studies have explored neurophysiologic biomarkers of suicidal ideation (SI) in healthy subjects. Here, we studied alterations of theta quantitative EEG (QEEG) in frontal regions associated with SI in young healthy subjects. Resting QEEG data were recorded from 90 young healthy subjects. The subjects were divided into two group based on Scale for Suicidal Ideation (SSI) scores: a high SSI group (n = 33) and a low SSI group (n = 57). Individual frontal electrodes (Fp1, Fp2, F7, F3, Fz, F4, F8) and central midline electrodes (FCz, Cz) were examined for absolute and relative power in the theta band. Clinical state and social support was assessed using the Hospital Anxiety and Depression Scale and Functional Social Support Questionnaire. We found that theta absolute and relative power in all channels was positively correlated with SSI, except Fp1, F7 and F8. The high SSI group showed higher theta relative power at F3, Fz, FCz, and Cz than the low SSI group. Theta relative power in the fronto-central region was significantly increased in the high SSI group compared to that in the low SSI group. Hierarchical regression analysis showed that SSI score was the most powerful predictor of fronto-central theta power. The findings suggest that brain electrical activity at the fronto-central region may be associated with differences in SI in young healthy subjects. EEG activity in theta band has clinical potential as a biomarker for preventing suicide.</P>

LC : Non-invasive Assessment of Fibrosis and Cirrhosis using Liver Fibrosis Measurement in Nonalcoholoic Fatty Liver Disease

( Jung Gil Park ),( Soo Young Park ),( Si Hyun Bae ),( Jae Young Jang ),( Do Young Kim ),( June Sung Lee ),( Ki Tae Suk ),( In Hee Kim ),( Heon Ju Lee ),( Woo Jin Chung ),( Byoung Kuk Jang ),( Jeong I 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Background: Protein-calorie malnutrition is frequently observed in patients with advanced liver cirrhosis. There have been continued interests in potential benefits of long-term oral branched-chain amino acid (BCAA) supplement in improving severity of liver disease. However, there are limited evidences in literature. The aim of this study is to evaluate the efficacy of oral BCCA in patients with advanced liver cirrhosis. Methods: This study is a multicenter retrospective cohort study involving thirteen centers in Korea nation-wide. The inclusion criteria are liver cirrhosis patients with Child-Pugh score 8 to 10. The major exclusion criteria are abnormal serum creatinine level, and hepatocellular carcinoma (HCC) with viable tumor. We analyzed improvement of Model for End-Stage Liver Disease (MELD) score, Child-Pugh score, incidence of cirrhosis-related complications, and event free survival. Results: Among 360 patients recruited, 171 patients (82 patients BCAA group and 91 patients control group) met inclusion criteria for analysis. There were no significant differences between 2 groups in baseline characteristics except history of HCC. The BCCA group showed significantly better MELD score than control group (P=0.047). There was no significant difference in incidence of cirrhosis-related complications between two groups (P=0.392). The development of HCC tends to decrease in BCAA group compared to control group (hazard ratio, 0.39; 95% confidence interval, 0.14-1.11; P=0.079). Conclusions: Long-term oral BCAA supplement has beneficial effects in patients with advanced liver cirrhosis. Further largescale prospective study is needed for delineation of beneficial effects of oral BCAA agent in advanced liver cirrhosis patients.