環境保全을 爲한 生態系 基本調査 硏究

姜寅求 동국대학교 대학원 1985 大學院硏究論集-東國大學校 大學院 Vol.15 No.-

This study was carried out to give basic information about pertinent green space management in industrial area, Ulsan which has being airpolluted. Recent research on The interaction between plants and air pollution was briefly reviewed. Total and annual biomass yield, leaf surface area, net assimilation rate, total sulfur content in foliages and visible injury were examined between various plant species and between the two regions which are airpolluted severely and lightly, respectively. The results obtained were as follows: 1. The vegetations including trees and agronomic crops were sparsely distributed around the industrial area in Ulsan. Among them, Pinus thunbergii, Pinus densiflora, Pinus rigida Alnus hirsuta and Quercus acutissima were major tree species producing poor yield. 2. In lightly polluted areas (Seongan and Bukjeong), P. rigida, P. thunbergii, P. densiflora, Q. acutissima, A. hirsuta and Robinia pseudoacacia showed good biomass yield in descending order, while P. densiflora, R. pseudoacacia, P. rigida and P. thunbergii did less yield in severely polluted areas(Yaeaum and Yeochon) 3. A. hirsuta and R. pseundoacacia among deciduous trees produced large leaf areas whereas P. thunbergii, P. rigida and P. densiflora were the best among coniferous trees. 4. Net assimiltion rate of trees growing in Seongan and Bukjeong areas was higher than that in Yaeaum and Yeochon areas 5. Trees growing in Yaeaum and Yeochon areas showed higher total sulfur contents in leaves than those in Seongan and Bukjeong areas. 6. Studied biomass yields indicated larger in the less polluted areas of Seongan and Bukjeong where vegetations are richer than the more polluted areas. 7. Total anounts of dry matter biomass produced from Ulsan area were estimated to be 150,714.68 tons. Annual production of dry matter biomass amounts to be 35,804.62 tons. Estimated amount for O_2 produced annually from the vegetated area(11.179ha) in Ulsan was 37,959.9 tons while that for SO_2 was 45.07 tons. 8. Low annual yield of biomass in Ulsan, in generel, was due mainly to worse environmental conditions. Thus, a further study is urgently needed for better management of green space as well as pollution control in Ulasn area.

뇌졸중 위험인자를 가진 어지럼 환자에서의 확산강조 자기공명영상

강형구,윤유상,이진희,박인철,이경룡,정상원,구홍두,김승호 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: The management of vertiginous patients is a great challenge to emergency physicians. We evaluated the diagnostic value of a diffusion-weighted image(DWI) in differentiating central vertigo from the peripheral vertigo in patients who presented no neurological symptoms other than risk factors for stroke. Methods: From March 2000 to February 2001, we retrospectively analyzed the cases of 68 patients who visited the emergency department with symptoms of isolated vertigo and who had risk factors for stroke. DWIs, computed tomograms(CT), and medical records were reviewed, and the final diagnose, the DWIs and the CT readings, the risk factors for stroke, and the time it took waiting for a DWI or CT scan were analyzed. Results: Of the 68 patients, 21(30.8%) had central vertigo: 15 vertebrobasilar transient ischemic attacks(VB-TIA), 4 brain stem infarctions, 1 cerebellar infarction, and 1 cerebellopeduncular infarction. The DWI showed a 28.6% sensitivity, a 97.9% specificity, and an 85.7% positive predictive value in diagnosing central vertigo. It also had a 100% sensitivity in detecting infarctions. Conclusion: A DWI had a comparable sensitivity to MRI in detecting central vertigo and small, but potentially, lethal infarctions in our patient population. We recommend clinical application of DWI in the emergency department evaluation of isolated vertigo patients with risk factors for stroke.

美國 各 大學의 體育館 施設 實態 調査硏究

金相九,姜仁燮 成均館大學校 科學技術硏究所 1984 論文集 Vol.35 No.1

For the purpose of investigation of the actual condition of each university gymnasium in U.S.A., I had visited directly there and investigated a number of documents. The conclusions are as follows. 1. Gymnasium facilities The athletic facilities of university are devided into four blocks; a playground, a gymnasium, a pool and a recreation center. Especially, I think that we must build a multi-purpose highstoried gymnasium which is constituted for special program. That is, theb asement should be constituted with pool and its supplementary facilities; the 1st story be constituted for the place of gymnastics, training, dancing, and tool lending; the 2nd story constituted with a great stadium for various sporting events and electromotive stand enlarging spectator scats as occasion demands; the 3rd story mainly a study room, a laboratory, a broadcasting studio, a photographing room, a conference room, which mint be used for school education, extraordinary athleticactvites, recreation, international games, the functions of local community. 2. Operation of Recreation Center Recreation center must take a administrative office, which should administrate programs about indvidual activites, intramural sports, club sports, instruction classes, recreation areas, the functions of public welfare facilities of school headed by the function of inside or outside the school. So I think a rational system is necessary in order to administrate them efficiently, the center should be administrated by the membership fee using the facilities. 3. Unification of School Athletic and. Social One I think that athletic facilities must be a social center of the organization of new inhibitant's space in modern world city space. In order to get effects, from the viewpoint of whole life education as being united of school education and social one, the facilities should be openel to the public as a place of physical activites or recreation after school hours or in holiday. Ultimately, I think that the balanced development of school education and social one through athletic activities will do positive role to accomplish a better society.

혈액 종양환자에서 Tobramycin의 임상약동학

신재국,신완균,장인진,신상구,김성민,배현주,최강원,김진규 대한화학요법학회 1990 대한화학요법학회지 Vol.8 No.1

항암화학요법을 받고 있던 중 감염으로 tobramycin을 투여받은 36명의 혈액종양 환자에서 tobramycin의 약동학적 특성을 비종양환자군에서의 population 값과 비교 검토하였다. 이들은 모두 정상 신기능을 가진 16세 이상의 성인남녀(21:15)백혈병 환자들이었다. 36명의 혈액종양 환자에서 산출된 tobramycin의 청소율 및 체내분포용적은 각각 120.3± 27.2ml/lg/hr 및 0.386± 0.11 L/㎏로 population 추정 치보다 유의하게 큰 값을 보였다.(P. <0.05).청소율과 체내분포용적을 해당 population 추정치로 나눈 비율치(ratio)의 평균값은 각각 1.47± 0.34 및 1.20± 0.34였다. 연령, hematocrit치, 혈청albumin치, 발열 및 항암화학요법기간과 tobramycin의 청소율 및 체내분포용적 사이에 유의한 상관관계는 발견할 수 없었다. 본 연구결과 혈액종양 환자에서 tobramycin 투여시는 적정혈장농도를 유지하기 위해 일반 환자군에 비해 용량의 증가 및 투여간격의 조정이 필요하며 지속적인 혈장농도 monitoring을 통하여 용법의 재적정화가 필요할 것으로 사료된다. The pharmacokinetics of tobramycin were evaluated in 36 hematologic malignancy patients undergoing anticancer chemotherapy and compared to the expected values from the population parameters. Total body clearance(mean : 12.3±27.2㎖/㎏/hr) and volume of distribution (mean : 0.386±0.11 L/㎏) in hematologic malignancy patients with normal renal function were significantly greater than those of estimated from population parameter distribution(P<0.05). The ratios of total body clearance and volume of distribution to the population estimates were 1.44±0.37 and 1.20±.034, respectively. No relationships were found between age, hematocrit, serum albumin, fever or duration of anticancer chemotherapy and pharmacokinetic parameters. It is suggested that the increment of tobramycin dose regimen wold be considered in patients with hematologic malignancy, and dose readjustment followed by close monitoring of plasma drug concentration would be required.

太谿穴의 臨床 活用에 대한 文獻考察

구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.

單一 排出源大氣汚染 短期모델에 관한 硏究 : Tracer Gas 에 의한 擴散實驗;Diffusion Experiment with Tracer Gas

李鍾範,姜寅求 江原大學校 附設 環境硏究所 1990 環境硏究 Vol.7 No.-

To evaluate the short term air pollution dispersion model, the diffusion experiment was conduct-ed on the flat terrain near Chuncheon. Sulfur hexafluorlde (SF_(6)) gas was used to determine the horizontal spread of plume (σy) for various meteorological conditions. This observed σy was compared with σy calculated by CRSTER medel. Results show that CRSTER model underestimates σy because averaging time adjustment is noe applied to calculate the σy. The scheme that can estimate the atmospheric stability more accurate than Turner method, was presented.

大氣汚染濃度의 發生顔度特徵및 推定法의 評價

이종범,강인구 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-

The aspects of the occurence frequency of SO_(2) concentration were studied with the observed data in Seoul and the scheme that is capable of estimating not only highest concentration for a variety of averaging times but also concentrations for arbitary occurrence frequency with long term arithmatic mean and geometric standard deviation data, was evaluated. The results of the statistical analysis show that the occurrence frequency is almost log normal except a few cases, and 3rd highest values of daily mean concentration were about 4.2∼5.2times higher than annual arithmatic mean. The evaluation with the observed hourly concentration shjows that the scheme fairly well estimate the short term concentration of arbitary occurrence frequence and it can be used for air quality management and environmental impact assessment.

人工湖를 중심으로한 貝類相 연구

Kang, In-Goo,Chung, Kyung-Soo,Suh, Jung-Soo 한국환경보건학회 1987 한국환경보건학회지 Vol.13 No.1

The study on shellfish fauna around eleven artificial lakes was carried out from April to September in 1986. The identified shellfishes in total surveyed area are composed of 13 species, 6 families, 4 orders, 2 classes and among them, the dominant species was Semisulcospira forticosta. Corbicula japonica which had been inhabited in Paltangho was collected in Chunchonho and Uiamho in this study. Consequently, the distributional area was gone up north. Especially, Radix auricularia, Parafossarulus manchuricus and Austropeplea ollula were collected in Paltangho and Uiamho are indicators of $\alpha$-mesosaprobe. Therefore it is necessary the countermearsure on management of water quality for the security of the source of water supply.

Anti-tumor effect of licochalcone-E is mediated by caspase-dependent apoptosis through extrinsic and intrinsic apoptotic signaling pathways in KB cancer cells

( In-a Cho ),( Kyeong-rok Kang ),( Su-gwan Kim ),( Do Kyung Kim ),( Chun Sung Kim ),( Sook-young Lee ),( Seung Sik Cho ),( Goo Yoon ),( Byung Soo Park ),( Jae-sung Kim ) 조선대학교 구강생물학연구소 2017 Oral Biology Research (Oral Biol Res) Vol.41 No.4

This study investigates the anti-cancer effects of licochalcone-E (Lico-E), a phenolic chalconoid derived from the genus Glycyrrhiza, in the human KB squamous cancer cell. Concentration-dependent cytotoxicity in KB cells increased following 24 hours of treatment with 12.5, 25, or 50 μg/ml Lico-E, with an estimated IC₅₀ value of approximately 25 μg/ml. Chromatin condensation, a typical apoptotic phenomenon, was observed in KB cells treated with Lico-E. Consistent with this finding, Lico-E increased caspase-3 activity in KB cells. FasL, a death ligand associated with extrinsic apoptotic signaling pathways, was significantly up-regulated by Lico-E treatment. Subsequently, the pro-apoptotic factor caspase-8, a part of the extrinsic apoptotic signaling pathway, was activated in a concentrationdependent manner by Lico-E treatments. Expression of anti-apoptotic factors such as Bcl-2 and Bcl-xL, components of the mitochondriadependent apoptotic signaling pathway, significantly decreased following Lico-E treatment. Conversely, expression of pro-apoptotic factors such as Bax, Bad, Apaf-1, and caspase-9 increased with Lico-E concentrations. Finally, Lico-E activated caspase-3 and Poly (ADP-ribose) polymerase (PARP) to induce cell death. Z-VAD-fmk significantly inhibited cell death through suppression of caspase-3 expression in KB cells treated with Lico-E. Taken together, Lico-E induces KB cell death through death receptor and mitochondriadependent apoptotic signaling pathways.

Determination of Microviscosity and Location of 1,3-Di(1-pyrenyl)propane in Brain Membranes

Kang, Jung-Sook,Kang, In-Goo,Yun, Il 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

We determined the microviscosity of synaptosomal plasma membrane vesicles(SPMV)isolated from bovine cerebral cortex and liposomes of total(SPMTL)and phospholioids(SPMPL)extracted from SPMV. Changes in the microviscosity induced by the range and rate od lateral diffusion were measured by the intramolecular excimerization of 1,3-di(1-pyrenyl)-propane(Py-3-Py). The microviscosity values of ht edirect probe environment in SPMV,SPMTL and SPMPL were 38.17,31.11,and 27.64 cP, repectively, at 37℃and the activation energies(E_a)of the excimer formation of Py-3-Py in SPMV,SPMTL and SPMPL were 8.236, 7.448 and 7.025 ㎉/mol, repectively. Probe location was measured by polarity and polarizability parameters of the probe Py-3-Py and probe analogues, pyrene, 1-pyrenenonanol and 1-pyrenemethyl-3β-hydroxy-22,23-bisnor-5-cholenate (PMC), incorporated into membranes or solubilized in reference solvents. There existed a good linear relationship between the first absorption peak of the ^1L_a band the polarizability parameter(n^2-1)/(2n^2+1). The calculated refractive index vaoues for SPMV,SPMTL and SPMPL were close to 1.50, which is higher than that of liquid paraffin(n=1.475). The probe location was also determined by using a polarity parameter(f-1/2f^1). Here f=(ε-1)/(2ε+1)is the dielectric constant function and f^1=(n^2-1)/(2n^2+1) id the refractive index function. A cprrelation eaisted between the monmer fluorescence intensity ratio and solvent polarity parameter. The probe incorporated in SPMV,SPMTL and SPMPL report a polarity value close to that of 1-hexanol(ε=13.29). In conclusion, Py-3-Py is located completely inside the menbrane, not in the very hydrophobic core, but displaced toward the polar head groups of phospholioid molecules,e.g., central methylene region of aliphatic chains of phospholioid molecules.