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      • KCI등재

        한국인의 항파상풍 항체 역가

        구홍두,최옥경,장석준,정구영,이정운,김승호 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

        Inspite of immunization, TETANUS remains a disease with a high morbidity and mortality rate. Tetanus has been still occurred more frequently in developing countries where immunization programs are inadequate. In Korea, there is a routine immunuzation schedule with diphtheria, pertussis, and tetanus(DPT) vaccines at 2,4,6 month after birth at 18 month. But further prophylactic programs are not exist. Moreover, we have usually used only passive immunization, tetanus antitoxin, as a prophylactic regimen for injured patients instead of guidelines of Center for Disease Control. The purpose of this study was to assess the baseline tetanus immunity state and to suggest the proper immunization schedule and adequate prophylactic guideline for injured patients in Korea. One hundred thirty one trauma patients from emergency department of Severance hospital from September to November of 1993 were included. Antietanus antibody titers of the patients were analyzed by ELISA assay. The mean antitetanus antibody titer was 0.728 ±0.236IU/mL. The titers were diminished rapidly with age. In pediatric group(age under 15), the mean titer was 3.251 ±0.426 IU/mL and in geriatric group(age over 64), the mean titer was 0.007 ±0.002 IU/mL which was below the minimal protective antibody titer(0.01 IU/mL). While all of the pediatric patients have protective antibody titer, only 69.2% of young adults(15-39, n=65), 56.7% of adults(40-64, n=30), and 57.2% of geriatrics(>65, n=14) have protective antibody titer. Our results suggest that tetanus prophylaxis is unnecessary in the age under 14. In other age groups, however, our data strongly support the need of prophyulaxis.

      • KCI등재
      • KCI등재
      • 산란광 광량 적산식 Digital Dust Indicator에 의한 도서관과 학생회관내 PM_(10) 농도의 일변화

        김만구,권영진,정영림 江原大學校 附設 環境硏究所 1997 環境硏究 Vol.14 No.-

        Diurnal variation of PM_(10) concentration was investigated for 24 sites in library including reading room, bookstock room, lobby, office and so on, and 9 sites in student building at Kangwon National University using scattering light integrated type digital dust indicator. The dimensional conversion factors for mass concentrations(K) were determined by comparing between the PM_(10) concentrations collected by PM_(10) high volume air sampler and the digital dust indicator. The dimensional conversion factor(k) was 3.33 for indoor air in this experiment. The higher concentrations were 649㎍/㎥day for smoking room in the library 242㎍/㎥/day for circle room in the student building. Most of spaces in the library except a office and bookstock rooms were over 150㎍/㎥/day of PM_(10) concentrations and 6 indoor spaces were over the guideline for indoor air quality in student building except a health center and two restaurants. Therefore, in should be required to make an improvement in the indoor air quaility for public facilities in the university buildings.

      • 이공산(異功散)의 in vitro에서 Cisplatin 유도 신장독성의 감소 효과

        정지창,장성구,이경태,노영수,안규석,오수명 慶熙大學校 1997 論文集 Vol.26 No.-

        In vitro model systems are increasingly used to investigate the mechanism of chemical-induced toxicity and for toxicological screening of new drug families. The effect of Ekongsan on the cytotoxicity induced by cisplatin on human and rabbit kidney cells was evaluated by tetrazolium-dye(MTT) assay. On the basis of Cl_50 value, cisplatin-induced cytotoxicity on human renal cortical cells was increased depend on concentration, whereas Ekongsan alone did not influence Simultaneous administration of cisplatin and Ekongsan, cytotoxicity of cisplain was reduced depend on the concentration of Ekongsan. With primary cultured proximal tubule cells results to reduce the cisplatin induced-cytotoxicity by Ekongsan was comparable to those with renal cortical cells. Based on these results, Ekongsan may has the potency to protect the nephrotoxicity induced by cisplatin.

      • 다중의문문과 비애매성의 결속원리

        정구영 청주대학교 대학원 1997 우암논총 Vol.18 No.-

        Epatein's(l992) Economy approach explains a peculiar restriction on the occurrence of WH-phrases in multiple questions in languages like English, the-fact that a wh-phrase normally may not undergo any kind of S-structure movement if it is to undergo LF-movement to a [+WH] position m a second step. However, we have seen that there are certain contexts where a WH-phrase can in fact optionally undergo S-structure movement, and subsequently move to its [+WH] scope position at LF, contrary to what is predicted by Economy. Such a situation occurs with partial WH-movement, WH-movement, WH-imperatives, WH-pied piping, WH-scrambling, and WH-reconstruction in languages as &verse as German, Korean, etc. Accordingly, we have suggested dispensing with the hypothesis that Economy restricts movement, and have advanced an approach in terms of the Principle of Unambiguous Binding(PUB). We have shown that the PUB accounts for all the data covered by the Economy approach - it rules out the pertinent constructions as improper movement configurations. At the same time, The PUB evades the objections raised against Economy. Furthermore, it sheds some new light on the classic issue of whether LF movement of WH-phrases may or may not apply successive-cyclically : WH-movement at LF can be successive-cyclic only if positions of the same type are involved, but not if movement mixes Spec-CP substitution positions and Spec-CP adjoined positions.

      • KCI등재

        Halon 1301과 Halon 대체 소화약제를 기포제로 이용한 포 소화약제에 대한 연구

        정기창,임성묵,이창섭,강영구,김홍 (사단법인)韓國火災 ·消防學會 1996 한국화재소방학회논문지 Vol.10 No.3

        포 소화약제는 물보다 비중이 가벼운 액체 가연물 또는 입체면이 많은 건물에서 포 수용액을 팽창 발포시켜 대상물을 덮어 씌우거나 봉쇄해서 질식소화 시킬 수 있다. 포 소화약제로 소화성능이 탁월한 수성막포(AFFF) 소화약제를 노즐에 의해 공기와의 혼합으로 포를 형성하는 기존의 방법과 다른 방법으로 본 연구에서는 Halon 1301 및 Halon 대체 소화약제를 기포제로 사용하여 소화성능과 팽창비를 향상시킨 소화약제를 개발하게 되었다. 개발한 Halon 1301과 Halon 대체 소화약제를 기포제로 사용한 수성막포 소화약제는 적은 양의 수성막포 수용액으로 많은 양의 포를 형성하므로 휴대용 포 소화기 또는 포 소화설비 등에 유용하게 사용할 수 있다. The AFFF(Aqueous Film Forming Foam : 3M Company's Light Water) agent are synthetic compounds that foams which are similar to those produced by protein based materials. The foam extinguishing agent was used in the extinguisher was the AFFF agent. We sought, however, to make other foams by using halon 1301(CF_3Br) and halon alternatives, such as HCFC Blend A(CHClF_2 82%, CF_3CHCl_2 4.75%, CF_3CHClF 9.5%, C_10H_16 3.75%), HFC-227ea (CF_3CHFCF_3). We selected these alternatives instead of air in order to raise the expansion ratio of the AFFF agent. By these means we discovered that it is possible to increase the expansion ratio of the AFFF agent up to 44 : 1 and up to 24 : 1 when HFC-227ea was used as a halon alternatives. Therefore our new foam extinguishing agents can be used in a portable extinguishers.

      • 太谿穴의 臨床 活用에 대한 文獻考察

        구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

        Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.

      • THE DEVELOPMENT OF THE EM-<TEX>$200^{TM}$</TEX> GAS-FILLED AFFF FIRE EXTINGUISHER FOR AUTOMATIC FIRE SUPPRESS10N SYSTEMS IN THE ENGINE COMPARTMENT OF AUTOMOBILES

        Jung,Ki-Chang,Kim,Hong,Kang,Young-Goo 한국화재소방학회 1997 한국화재소방학회 학술대회 논문집 Vol.1997 No.-

        In recent years, the number of vehicle fires, as well as the number of motor vehicles, has been increasing rapidly. Therefore, several types of automatic fire suppression systems for the engine compartment of automobiles have been developed to extinguish automobile fires, and most of these systems use halon 1301 as a fire extinguishing agent. Due to environmental concerns, the phase-out of halons has been announced, so now there is a need to replace halon 1301. For this, a 1,1,1,2,3,3,3-heptaflouropropane (HFC-227ea, FM-<TEX>$200^{TM}$</TEX>) gas-filled Aqueous Film- Forming foam (known as AFFF) extinguisher was devised even though air foam extinguishers could be used. This is because the air in the foam bubbles is a source of oxygen required for the combustion reaction. It can be surmised that it is possible to increase the fire extinguishing efficiency of AFFF by filling in foam bubbles with a gaseous extinguishing agent. The best choice is the FM-<TEX>$200^{TM}$</TEX> gas-filled AFFF, Which has the maximum expansion ratio of 62:1. This makes it possible for the expanded foam to rapidly fill the engine compartment.

      • KCI등재후보

        일개 지역 전공의들의 주사침 상해

        박신구,이종영,송정흡,유재영,최태성 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.1

        목 적 : 병원 종사자들 중에서 전공의들의 주사침 상해의 실태를 파악하고, 주사침 상해 발생의 관련 요인을 알아보고자 하였다. 방 법 : 2000년 7얼에 대구지역에 소재한 전공의 수련병원 중 대학병원 2개소와 종합병원 1개소의 전공의 695명 전원을 대상으로 실시한 자가 기입식 설문지를 통하여 자료를 얻었단. 정확하게 응답한 443명(63.7 %)을 최종분석대상으로 하였다. 결 과 : 새로운 연차가 시작된 4개월 동안 경험한 주사침 상해는 응답자 443명중 200명으로 45.1 %이었고, 평균상해횟수 1.8회, 1000명당 1년 상해율은 5,377건 이었다. 업무특성에 따라 인턴이 96.5 %, 외과계 레지던트가 40.6 %, 내과계 레지던트가 34.4 %의 주사침 상해를 경험하였다. 주사침상해 발생의 관련요인을 분석하기 위해 다중 로지스틱 회귀분석(multiple logistic regression analysis)을 시행하였고, 분석결과는 내과계 레지던트에 비해 인턴이, 12시간이하 근무시간에 비해 16시간이상의 근무시간이 유의한 관련요인으로 나타났다. 결 론 : 병원종사자들 중에서 전공의들은 높은 주사침 상해율을 나타내고 있다. Objectives : This study was conducted in order to assess the experience of needle stick injury among interns and residents working in hospitals during the previous 4 nonths. Methods : We conducted a questionnaire survey of 695 interns and residents working in two university hospitals and one general hospital in Tague city. Four hundred and forty three of those questioned(63.7 %) fully responded. Results : Two hundred of the respondents(45.1 %) suffered at least one injury. Respondents suffered an average of 1.8 injuries. 96.5 % of interns, 40.6 % of surgical residents and 34.4 % of non-surgical residents suffered at leat one injury. According to multiple logistic regression, Intern status and an increased amount of working time is associated with high risk of needle stick injury. Conclusions : This study demonstrates that interns and residents suffer a high rate of needle stick injury.

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