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      • KCI등재

        연립 주택 화재시 유독가스 방출 특성과 Rats를 이용한 독성평가

        김홍,강영구,김동현,정기창,이창섭,김운형 한국화재소방학회 2002 한국화재소방학회논문지 Vol.16 No.3

        화재에 의한 독성가스의 노출은 인간에게 있어서 화재시 생명에 아주 위험한 요소일 것이다. 다양한 화재에 의한 독성가스의 노출 중 본 논문에서는 경기도 안산시 재개발지구에서 한 연립주택을 이용하여 실제화재와 같은 조건으로 화재 시험을 하였다. 화재시 발생하는 가스 CO, CO_2, O_2, SO_2, NO 및 NO_2등을 측정하였으며, 발생하는 가스를 실험동물인 백서(S.D)에 노출시켜 2분간격으로 혈액을 체취하였다. 독성평가를 위하여 백서의 혈액과 혈청 중 Glucose, AST(GOT), ALT(GPT), CBC Count 및 CO(carboxy)-Hb를 분석하였다. 폭로되는 CO의 농도와 백서의 혈액중 CO-Hb 농도사이에 양-반응 관계(dose-response relationship)를 보였다. It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confronting people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which include CO, CO_2, O_2, SO_2, NO and NO_2, were measured by a gas analyzer A group of lab rats were exposed to the toxic gases released from fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST(GOT), ALT(GPT), CBC Count and CO(carboxy)-Hb in the blood samples. Shown from the analysis is the does-response relationship between the CO concentration that rats were exposed to and the CO-Hb concentration in rat blood.

      • KCI등재

        본질적 난연 및 내열성 헤테로환식 폴리머의 특성에 관한 연구

        김홍,강영구,유호석 한국산업안전학회 1997 한국안전학회지 Vol.12 No.3

        본질적인 난연 및 내열성의 PQXS, PIQS, PQS 3종류의 폴리머를 2, 3-dichloroquinoxaline, 1, 3-dichloroisoquinoline, 4, 7-dichloroquinoline을 각각 출발 물질로 하여 합성하였다. 이들을 FT-IR, UV/Vis 분광분석, DTA, 원소분석 등에 따라 특성분석을 행하였다. 이들 폴리머소재는 내열 및 난연특성 시험에서 녹는점 기준 350℃ 이상의 높은 내열성과 LOI값 기준으로 41∼42의 높은 수치의 난연특성을 나타내었으며 또한 수직연소시험에서 UL 94 V-O 등급의 높은 난연특성을 나타내었다. The intrinsic flame retardant and heat resistant polymers such as PQXS[poly(quinoxaline)sulfide], PIQS[poly(isoquinoline)sulfide] and PQS[poly(quinoline)sulfide] were synthesized from 2, 3-dichloroquinoxaline, 1, 3-dichloroisoquinoline and 4, 7-dichloroquinoline. They were characterized by FT-IR, UV/Vis spectroscopy, DTA and elemental analysis. The melting point above 350℃ of the polymers show higher than that of the heat resistant PPS polymer(mp. 295℃). In the LOI test, the polymers exhibit an intrinsically high flame retardant property having the LOI values in the range of 41∼42. The vertical burning test for the polymers also show an UL 94 V-O performance.

      • KCI등재

        주변부 고립결절성 폐암의 전산화단층촬영 소견

        김홍,김옥배,우성구,서수지,김성수,Kim, Hong,Kim, Ok-Bae,Woo, Seong-Ku,Suh, Soo-Jhi,Kim, Sung-Soo 대한영상의학회 1985 대한영상의학회지 Vol.21 No.5

        It is diffidult to distinguish benign from malignant, ulmonary nodule by conventional roentgenologic examination. But CT makes it easier to evaluate adjacent parenchymal invasion, pleural or mediastinal extension, or early metastasis to intra- or extrathoracic lymph node as well s distant organs, although only a solitary peripheral pulmonary nodule is seen on plain radiograph. Authors reviewed CT of 22 cases of histopathologically confirmed primary lung cancer seen as a solitary peripheral pulmonary mass from May 1980 to September 1984 at Dongsan Medical Center, Keimyung University. The results are as follows: 1. The incedence was most common in the 6th decade(36%). Male to female ratio was 10:1 and 2 females all had bronchioloalveolar cell carcinoma. 2. The distributions of histologic cell type were as follows: squamous cell carcinoma 40%, adenocarcinoma, small cell carcinoma, bronchioloalveolar cell carcinoma and unclassified carcinoma 14% in each cases, and adenoid cystic c rcinoma 4%. 3. The computed tomographic findings were as follows: a) Superior and posterior basal segments of both lower lobes were most frequently involved(68%). b) The mean diameter of the mass was 48mm, and most common in the range of 30-49mm in the greatest dimension(46%). c) The mean CT attenuation value was 57 H.U., and most common in the group of 41-70 H.U.(64%). d) Lymph node metastasis was found in 13(59%) of 22 cases, and the involved nodes were as follows: hilar nodes 10 cases, paratracheal nodes 8 cases, subcarinal nodes 7 cases and extrathoracic nodes 3 cases. In 2 of 3 cases with small cell carcinoma, diffuse multiple lymph nodes were involved. e) Distant metastasis was seen relatively early in 3 cases: cerebral metastasis in 1 case of squamous cell carcinoma, right adrenal metastasis without intrathoracic lymph node metastasis or invasion of adjacent structures in 1 case of bronchioloalveolar cell carcinoma, and liver and bone metastases in 1 case of unclassified carci oma. f) Adjacent pleural or mediastinal invasion was found in 7 cases(32%): pleural invasion alsong chest wall in 4 cases, and invasion of adjacent mediastinal pleura in 3 caes of 2 squmous cell carcinoma and 1 unclassified carcinoma. g) Calcifications within the mass were found in 5 caes(23%), and most common in squamous cell carcinoma(3 caes). In all cases, a few granular calcifications were seen along the peripheral margin of the mass. h) Tumor necrosis was seen in 4 cases(18%), and 3 cases were squamous cell carcinoma, and one of them showed irregular central cavitation. i) The margins of tumor were irregularly lobulated with radiating spiculations in all except one of adenoid cystic carcinoma, which revealed oval shaped, smooth clear margin. j) In 9(41%) of 22 cases, some enlargement of pulmonary vessels with perivascular linear infiltrations were found in the adjacent lung parenchymes of the mass, which were thought to be retrograde perivascular lymphangitic spread along pulmon ry vessels.

      • KCI등재

        고령환자의 충수주위농양 진단시 전산화단층촬영의 의의

        김홍,김정식,김옥배,우성구,서수지,Kim, Hong,Kim, Jung-Sik,Kim, Ok-Bae,Woo, Seong-Ku,Suh, Soo-Jhi 대한영상의학회 1989 대한영상의학회지 Vol.25 No.4

        CT is useful for the elderly patient in whom the diagnosis of periappendiceal abscess has not been suspected clinically due to an atypical clinical presentation. CT findings and its clinical applicability of periappendiceal abscesses were reviewed retros-pectively in 11 patients older than 40 years. The correct diagnosis was possible clinically in 4 patients(36%) The CT findings were mainly cystic (45%) of mixed (36%) masses which were located inferomedially to cecum(55%) or medially to right-sided colon (27%) The common associ-ated findings were adjacent peritoneal and intestinal thickenings mesenteric and/or omental ated findings were adjacent peritoneal and intestinal thickenings. mesenteric and/or omental infiltrations in most of the cases and retroperitoneal extensin of the inflammatory process(55%) . However there we five false-positive diagnoses in patients with a fluid-filled cecum a noncomplicated acue appendicitis and three chronic inflammatory diseases of the pericecal area. CT has the potential advantage of directly imaging the periappendiceal inflammation with a full assessment of the nature localization and extension of the abscesses and may guide percutaneous drainage of abscesses as an alternative to surgical drainage.

      • KCI등재

        담즙낭종 : 방사선학적 진단과 치료

        김홍,우영훈,우성구,Kim, Hong,Woo, Yung-Hoon,Woo, Seong-Ku 대한영상의학회 1990 대한영상의학회지 Vol.26 No.4

        The localized intraabdominal bile collection or biloma has recently been diagnosed in increased frequency due to the wide spread use of US, CT, DISIDA scintigram, and radiologically guided percutaneous needle aspiration with or without subsequent catheter drainage. The underlying cause of biloma is trauma or iatrogenic injury which includes abdominal surgery, percutaneous drainage or PTC. We experienced 20 patients with 22 biloma diagnostically confirmed by DISIDA scan, image-guided needle aspiration, percutaneous catheter drainage and/or operation. Of the 22 biloma, 7 were intrahepatic and 15 were extrahepatic, Of the 15 extrahepatic biloma, 7 were in partially hepatectomized bed, 3 were subhepatic, 3 were right subphrenic and 1 was subcapsular. We were able to determine the infectivity in 16 biloma and of these 12 biloma were found to be infected. Percutaneous drainage was performed on 20 biloma in 18 patients : by a needle aspiration with irrigation on 2 patient and by perc taneous catheter drainage on 18bilomas. Overall success rate of the drainage was 90%. Cause of the two failures were CHD stone with choledochoduodenal fistula and recurrent hemobilia with acute cholecystitis. We describe the processes in reaching the diagnosis of biloma, propensity of biloma to purulent intrahepatic or perihepatic abscess formation, and the necessity of percutaneous radiologic catheter drainage as an optimal management.

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