척추질환 입원환자의 연도별 변동추이에 대한 통계적 고찰

박경수 ( Kyung Su Park ),이준환 ( Jun Hwan Lee ),정석희 ( Seok Hee Chung ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.4

Objectives : The aim of this study was to find the change in the number of inpatient with spine disease, data were reviewed on inpatients who was diagnosed as spine disease in the Kyung-hee Medical Center(KHMC) for 25 years(1980~2004). Methods : Analysis data of the number of spinal disease was based on the KHMC annual report for 25 years(1980~2004). Results : 1. The number of inpatient in KHMC with spine disease has been increasing during 25years from 1980 to 2004(p-value:0.000) 2. The number of inpatient in KHMC with ankylosing spodylitis(AS) is increasing during 25years from 1980 to 2004(p-value=0.000) 3. The number of inpatient in KHMC with spinal stenosis is increasing during 25years from 1980 to 2004(p-value=0.000) 4. The number of inpatient in KHMC with herniated nucleus pulposus of cervical spine(HNP of C-spine) is increasing during 25years from 1980 to 2004(p-value=0.000) 5. The number of inpatient in KHMC with herniated nucleus pulposus of Lumbar spine(HNP of L-spine) is increasing during 25years from 1980 to 2004 (p-value=0.007) Conclusions : It is suggesting that the number of patients of spinal stenosis and HNP of L-spine increase at KHMC.

The effect of neuropeptides on secretion of Interleukin-8(IL-8)

Kim, Kyung-Jun,Park, Sang-Hyuk,Choi, Kyoung-Kyu,Park, Sang-Jin 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.3

본 연구는 치수조직, 치은, 치주인대로부터 배양된 조직을 SP (Substance P)로 4시간, SP, CGRP (Calcitonin Gene-related Peptide), Tumor necrosis factor-α (TNF-α)로 8시간 자극 후 RNase Protection Assay를 시행하고, IL-8의 분비량을 측정해 다음 결과를 얻었다. 1. IL-8 mRNA는 모든세포에서 발현됐다. 2. IL-8 mRNA 발현은 SP (10^(-5)M)와 SP (10^(-8)M)로 4시간 자극 시 증가되지 않았다. 3. IL-8 mRNA 발현은 SP (10^(-4)M)와 CGRP (10^(-6)M)로 8시간 자극 시 증가되지 않았다. 4. TNF-α (2 ng/㎖) 자극 시, IL-8 mRNA 발현이 증가됐다. 5. 치은 세포를 CGRP (10^(-6)M)로 8시간 자극 시, IL-8 분비량이 증가했다 (p < 0.05). 6. 치주인대 세포를 SP (10^(-4)M)로 8시간 자극 시 IL-8 분비량이 증가했다 (p < 0.05). We investigated the secretion of Interleukin-8 (IL-8) from ginviva and periodontal ligament stimulated with Substance P (SP) and Calcitonin Gene-related Peptide (CGRP). Gingiva (GF), periodontal ligament (PDLF) and pulp (PF) tissues were collected from extracted instact 3rd molars. Cultured cells were stimulated with different concentrations of SP for 4 hrs, and stimulated with SP, CGRP and Tumor Necrosis Factor-α (TNF-α) for 8 hrs. Then RNase Protection Assay was carried out. ELISA was performed using supernatants of stimulated cells for quantitative analysis of IL-8. Results were assessed using supernatants of stimulated cells for quantitative analysis of IL-8. Results were assessed using student t-test with significance of P < 0.05. According to this study, the results were as follows: 1. IL-8 mRNA was detected in all type of cells studied (PF, GF and PDLF). 2. IL-8 mRNA expression was not increased after stimulating 4 hrs with SP (10^(-5)M) and SP (10^(-8)M) compared with Mock stimulation in all type of cells studied. 3. IL-8 mRNA expression was not increased after stimulating 8 hrs with SP (10^(-4)M) and CGRP (10^(-6)M) compared with Mock stimulation in all type of cells studied. 4. TNF-α (2 ng/㎖) increased the expression of IL-8 mRNA in all kind of cells studied. 5. The secretion of IL-8 from GF was increased 8 hrs after the stimulation with CGRP (10^(-6)M) (p < 0.05). 6. The secretion of IL-8 from PDLF was increased 8 hrs after the stimulation with SP (10^(-4)M) (p < 0.05). Calcitonin Gene-related Peptide (CGRP) increased Interleukin-8 (IL-8) which plays an important role in chemotaxis of neutrophil in Calcitonin Gene-related Peptide (CGRP) gingival tissue, whereas Substance P increased the secretion of IL-8 from periodontal ligament.

K3에 축적된 내부 응력이 피로 파절에 미치는 영향

김준영,김진우,조경모,박세희 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

Objectives: This study aimed to evaluate the relationship between the cyclic fatigue of a K3 file and internal stress intentionally induced until the activation of the auto-stop function of the torque-controlled motor. Materials and Methods: K3 (Sybron Endo) .04 and .06 taper, size 25, 30, 35, 40 and 45 were used in this study. To give the internal stress, the K3 files were put into the .02 taper Endo-Training-Bloc (Dentsply Maillefer until the activation of the auto-stop function of the torque-controlled motor. The rotation speed was 300 rpm and torque value was 1.0 N·cm. K3 were grouped by the number of induced internal stress and randomly distributed to 4 experimental groups (n = 10, Stress 0 [control], Stress 1, Stress 2 and Stress 3). For measuring the cyclic fatigue failure, the K3 files were worked against a sloped glass block and time for file separation was recorded. Data was statistically analyzed Statistical analyses were performed using two-way ANOVA and Duncan post-hoc test at p < 0.05 level. Results: Except .04 taper size 30 in Stress 1 group, there were statistically significant differences in time for file separation between control and all experimental groups. K3 with .04 taper showed higher cyclic fatigue resistance than those of .06 taper. Conclusion: In the limitation of this study, the cyclic fatigue of the K3 file was influenced by the accumulated internal stress from use until the auto-stop function was activated by the torque-controlled motor. Therefore, clinicians should avoid the reuse of the K3 file that has undergone auto-stops. (Restor Dent Endod 2012;37(2):74-78)

성인병에 대한 한방치료법(증치의학과 사상의학)에 관한 연구 : 고혈압에 대한 한방치료법(중치의학과 사상의학)에 관한 연구

박동일,김영균,안창범,이인선,김종원,권정남,장경전,이인선,이성근,장용우,신영민 동의대학교 한의학연구소 1999 동의한의연구 Vol.3 No.-

We had a result of the treatment as below when is devided Korean medicine Tx.. Western medical Tx., Cooperative Tx.. 1) At the improvement of BP control, an average in Korean medicine Tx. (from 170㎜Hg/100㎜Hg to 150㎜Hg/90㎜Hg), an average in Western medical Tr. (from 170㎜Hg/100㎜Hg to 130㎜Hg/80㎜Hg), an average in Cooperative Tx.(from 180㎜Hg/110㎜Hg to 130㎜Hg/90㎜Hg), generally all pars had improvements of BP control. But it is not significant of each case. 2) At the improvement of symptoms by the apologetics, Cooperative Tx. is profitable in cases of 'GanHwa',' DamEum', 'EumYangYangHer', 'EumHer'. Korean medicine Tx. is superior in case of 'GiChe'. 3) At the improvement of symptoms by a questionnaire, Korean medical Tx., Western medical Tx., Cooperative Tx. groups had improvements, but each practice group didn't have specific significance. Only it was somewhat profitable to Korean medical Tx. in the 210㎜Hg/110㎜Hg, Western medical Tx. in the 180㎜Hg/110㎜Hg, Cooperative Tx, in the 170㎜Hg/90㎜ Hg. 4) There are the apparent improvements in patients whose BP are over 200㎜Hg of Korean medical Tx. group, whose BP are over 190㎜Hg of Western medical Tx. group and whose BP are over 170㎜Mg of Cooperative Tx. group. There are the improvement of diastolic BP in 110㎜Mg(Korean medical Tx., Western medical Tx.) and 90㎜Hg(Cooperative Tx.). 5) At the improvement of Pulse pressure, generally Pulse pressure are decreased. There are similar improvements in all of Korean medical Tx., Western medical Tx., and Cooperative Tx.. 6) At the Symptomatic approvement according to ages, Korean medical Tx., Cooperative Tx. are somewhat good for his twentieth, and Western medical Tx. is somewhat good for his forties. 7) the correlation of Obesity-grade and BP, as Obesity-grade is higher as BP is higher, but there are no similarity in the improvement. 8) At the EAV improvements, as examination into correlation with the point of 1~3th, we could get results as below. There are high improvements of DRHTM, DRALM, DLLYM, DLLIM in Cooperative Tx. There are high improvements of DRPASI, DLLARI in the Korean medical Tx. group. There are high improvements of DRFADM in Western medical Tx. group.

Backpropagation 학습알고리즘을 이용한 형상검출

박경우,조정래,이기준 광주보건대학 1997 論文集 Vol.22 No.-

The Backpropagation learning method is composed of input layer, Middle layer, and Output layer as a Hierarchical Network. Because we can settle Weight of Middle layer using difference which is output value of Output layer and Error value, in proportion to the times of learning, we can obtain a good quality of output layer.

위축성 비염(AR) 이환돈에서 분리된 Bordetella bronchiseptica의 성상

박세종,장경수,전무형 충남대학교 수의과대학 동물의과학연구소 1994 動物醫科學硏究誌 Vol.2 No.-

During 2 years from 1992 to 1994, prevalence of atrophic rhinitis(AR) in the pig herds located in the Western Chungnam was investigated, and isolation of B bronchiseptica was attempted for the pigs manifested with the clinical signs of atrophic rhinitis. The isolates were characterized and identified in aspects of biochemical properties, antigenicity, drug sensitivity and pathogenicity. The results through the experiments are summarized as follows; 1. The prevalence of clinical cases of artrophic rhinitis was recorded by 12.7% in the group that is the sows and piglets vaccinated, 28.9% in the group that is the sows only vaccinated and 39.8% in the group of the non-vaccinated groups. In th slaughter house, 53(24.8%) of 214 pigs examined exhibit the AR lesions. 2. A total of 189 strains of B bronchiseptica were isolated from the pig herds. Isolation rates were 12.6% in the group that is the sows and piglets vaccinated, 34.1% in the group that is the sows only vaccinated and 45.7% in the group of the non-vaccinated groups. Isolation rate in the specimen from the slaughter house was 93(43.5%) of 214 pigs examined. Of the AR-non-vaccinated group, the piglets aged between 61 to 90 days revealed the highest isolation rate of 58.5%. 3. Biochemical and serological propertities of 189 isolates were very similar to those of the reference B bronchiseptica phase I type, indicating that most of isolates are B bronchiseptica phase I type. 4. In antimicrobial drug susceptibility, 87.3% of 189 isolates was susceptible to chloramphenicol, 79.9%, to amikacin, 64.6%, to cephalothin and less than 35.4% to others. 5. The whole cells and bacterial filtrates of the isolates were inoculated to guinea pigs and mice. The isolates showed the high pathogenicity and dermonecrotoxicity. 6. In SDS-PAGE analysis, the isolates presented the identical protein profiles to the reference standard strains.

우리나라 老年層의 衣服色嗜好에 관한 硏究

朴準慶,姜順熙 漢陽大學校 韓國生活科學硏究所 1987 韓國 生活 科學 硏究 Vol.- No.5

According as our society has taken rapid development in material civilization and urbanization, the clothes has gained the recognition of its own considerable value in the aspect of social psychology. Though the old aged are inclined to increase every year, there is none the study of their clothes. Therefore, there is necessity for study about the adequate clothing habits suitable to the personality of the old aged on the basis of the change of the society. I investigated the like and dislike and the classiffied preference by seasons for colors of the old aged by sexes, ages and the degrees of school career focusing on this point. The method of the study consisted of the following procedures. First, I made a color chart based on 56 colors which was chosen among 98 colors which categorized by Japanese Color Institute. Second, I made the question papers, and then had a personal interview with the 228 peoples whose age ranges were over 50 years old.

급성 유기인제 중독환자의 혈청 Cholinesterase 활성도와 임상적인 의의에 관하여

전동석,김재룡,박승국,김윤년,이경민,윤덕구 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

To study the pseudocholinesterase acticity and its clinical significance in patients with acute organophosphate poisoning, Authors checked the serum cholinesterase activity in 49 normal subjects and 31 acute organophosphate poisoned patients. The results were followings. 1. The mean pseudocholinesterase activity f normal subjects was 1271 IU/L in male and 1131 IU/L in female. The total mean cholinesterase activity was 1209/ IU/L. 2. The pseudocholinesterase activity of patients were significantly reduced compare to normal. 22 patients(73%) were below 10% of normal, 6 patients(20%) were between 10-20% of normal and only 2 patients (7%) were between 20-50% of normal. 3. As a whole there was more depressed cholinesterase activity in patients with comatous and drowsy mentality, but there was no statistically significant difference between three groups. 4. The pseudocholinesterase activity in patients with respiratory failure was more depressed than without respiratory failure, but there was no statistically significant difference between three groups. 4. The pseudocholinesterase activity in patients with respiratory failure was more depressed than without respiratory failure, but there was no statistically significant difference presented. 5. The mean arterial blood gas checked on arrival was pH 7.386, PaO?? 66mmHg, PaCO?? 38mmHg 02 Saturation 91%. There was noted no statistically significant correlation between pseudocholinesterase activity and these parameters. 6. The pseudocholinesterase activity on the 1st day of admission was 5.7% of normal and progressively increased during admission. On the 14th day of admission, the pseudocholinesterase activity was 35.5% of normal and it takes 20 days to reach 50% of normal. Authors concluded that serum cholinesterase activity of acute organonphosporus poisoned patients were markedly depressed and progressively increased during admission. As a whole the pseudocholine-sterase activity seemed to be related to the clinical findings but no statistically significant difference was found.

직교영역에서 강건한 로보트 매니퓰레이터 제어기 설계

박종국,배준경 慶熙大學校 1988 論文集 Vol.17 No.-

A simple scheme for linear multivariable control of robot manipulator to achieve trajectroy tracking in cartesian space is described in this paper. The control scheme is derived from linear multivariable theory and is consisted of multivariable feedforward and feedback controllers. The feedforward controller is minimal inverse of the linearized model of robot dynamics and contained only proportional double-derivative(PD^2) type. This controller ensures that the manipulater joint angles track any reference trajectories. The feedback controller is of proportional derivative (PD) type and achieves stability and pole placement. This controller reduces any initial tracking error to zero as desired and also ensures that robust steady state tracking of step-plus exponential trajectories is achieved. To show the performance of control system, the proposed scheme is simulated of the 2 link planar manipulator using the VAX 11/780 computer.

신경정신증상을 수반한 Wilson씨병 2례

박경준,최영민,오석환 인제대학교 1990 仁濟醫學 Vol.11 No.1

신경정신 증세를 동반한 Wilson씨병 2례를 치험하였기에 문헌 고찰과 함께 이를 보고한다. We experienced two cases of Wilson's disease that presented with both neurological and psychiatric symptams, Such as dysphagia, dysarthria, gait disturbance, emotional lability and immaturity At first, we confused it with conversion disorder and functional psychosis because of its psychiatric Symptoms. Later, the presence of Kayser-Fleischer corneal ring and additional laboratory findings, such as a diminution in serum ceruloplasmin and an increased urinary excretion of copper, made us diagnose this rare condition accurately. In treatment we prescribed a chelating agent, D-penicillamine in divides oral doses.