입원치료를 요하는 소아의 급성복증

배택환,김준식,유인술,조준필,이철주,민영기 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1

The acute abdomen defined as an acute abdominal condition which needs immediate decision for treatment is one of the most common cause for emergency care. One thound six hundreds nine patients were visited to pediatric emergency center due to acute abdomen. To aid in early diagnosis and proper treatment, a clinical review was made on 278 cases of acute abdomen under 15 yrs old which admitted to Pediatrics and General surgery via emergency center from June of 1994 to May of 1995. The results as follows: It was 17.3% of total visiting to pediatric emergency center due to gastrointestinal sysmptoms. The sex ratio(Male: Female) was 2.35:1. Acute gastroenteristis was the most common acute abdominal condition(54%) and followed by acute appendicitis(17.9%), and intussusception(13.9%). The most common chief commplaint was vomiting(58%) and followed by abdominal pain(39.4%), diarrhea(35.8%), and fever(42.1%). One hundred fifty-five patients were visited to pediatric emergency center via local clinic and thirty patients via OPDs. The operations were done in 75 patients. Among them, immediate operation were done in 60 patients and delayed operations were done in 15 patients, but there is no difference in complication.

Arthrobacter simplex의 Steroid △^1-dehydrogenase의 유도와 유도성 스테로이드의 성질

배무,오영주,민태경,이미경 이화여자대학교 생명과학연구소 1991 생명과학연구논문집 Vol.2 No.-

Arthrobacter simplex IAM 1660의 스테로이드 Δ^1-dehydrogenase에 대한 각종 steroid의 유도조건과 효과를 검토하였다. 그 결과 시험한 스테로이드 중 hydrocortisone이 가장 큰 효과를 나타냈고 progesterone, prednisolone, prednisone, androstendione의 순으로 유도효과를 보였고, 스테롤에 의해서는 유도효과가 낮았다. 유도 스테로이드의 특성으로는 스테로이드 모핵 C-3위가 수산기인 것보다 캐톤기이며 C-4위에 이중결합이 존재하고 스테로이드 D고리의 측쇄가 짧은 것이 유도효과가 높았다. 유도물질의 첨가시기는 대수증식기 초기가 최적이었으며 농도는 hydrocortisone의 경우 0.1%가 좋았으며 효소의 유도시간은 15시간이 최저이었다. 효소유도시 배양온도는 30℃가 가장 좋았고 초기 배양액의 pH는 6.5에서 8.0까지 큰 차이가 없었지만 pH6.5일 때 비교적 높은효과를 나타내었다. Hydrocortisone에 의해 유도된 균체효소의 Δ^1-dehydrogenase 수소반응의 기질특이성을 검토한 결과 progesterone, testosterone,cholestenone이 Δ^1-탈수소 반응산물로 전환되었다. Since steroid Δ^1-dehydrogenase synthesis has been known to be inducible, the mechanism of the enzyme induction of Arthrobacter simplex IAM 1660 was investigated. Among various steroids tested for inducers, hydrocortisone was the most effective inducer when hydrocortisone was used as a substrate for steroid Δ^1-dehydrogenase. Steroid Δ^1-dehydrogenase sysnthesis was effectively induced by progesterone, prednisolone and androstenedione, while the enzyme was less induced by cholesterol and not by phytosterols. The results suggest that the presence of 3-keto group and short side chain of sterodids are the favorable factors for the induction of the Δ^1-dehydrogenase synthesis. The enzyme was induced at the highest level when hydrocortisone was added at early log phase to the concentration of 0.01% of the culture and the culture was grown for 15 hours.

산업장 근로자의 소음성 난청 발생요인에 관한 연구

주인하,이태용,조영채,이영수,이동배 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

This study performed to find out risk factors of hearing loss. The subjects of investigation were workers working in a paper mill under permissible exposure level(PEL) of noise. The results were as follows: 1. The noise induced hearing loss could be occurred under PEL. 2. The most prominent factor causing hearing loss was the working duration. 3. The risk factors of hearing loss in working under PEL were not similar to those workers of above PEL. 4. Under PEL, the individual susceptibility may be more important risk factor of hearing loss than others.

객체 중심 데이타베이스의 설계방법론 및 스키마생성 자동화 도구의 구현에 관한연구

주해종,박영배 명지대학교 공학기술연구소 1989 공학기술연구소 논문집 Vol.4 No.-

The Object-Oriented DB is highly popular on the several parts of applications for a good many advantages. One way, the business of DB design has increased owing to usage increasement of information system, so the needs of design methodology which is systematic and reasonable have appeared. In this paper, we propose the design methodology of Object-Oriented Database. Also, as the topic of this paper, we implement ASTO (Automatic Schema Generation Tool for OODB) using the proposed design methodology. The tool was implemented using C Language on IBM-PC/AT.

신이식환자에서 Thiopurine Methyltransferase의 활성이 Azathioprine 치료에 미치는 영향

조주연,배균섭,유경상,이소영,장인진,신상구,김상준,하종원,안규리 大韓臨床藥理學會 2000 臨床藥理學會誌 Vol.8 No.1

스위치드 릴럭턴스 전동기의 전류 파형

안영주,배규환,조철제 釜山工業大學校 1995 論文集 Vol.37 No.-

In this paper, a control method to flow the flat top current into the expected phase of variable reluctance motors(VRMs) is described. Current waveforms of SRM are directly related to the VRM performances. These are greatly influenced by topologies of driving converter. In order to flow the flat top current in the expected phase, conditions of excitation voltage such as the magnitude and on/off timing should be found out. To verify this control method, SRM drive system of a 6/4 pole VRM, controlled rectifier and classic inverter is constructed and tested. The experimental results show that this control method performs well the flat top current.

A Study on Protection of Maternal Antibody against Hantavirus in Rats

우영대,--,--,--,--,-- 대한의생명과학회 2005 Biomedical Science Letters Vol.11 No.1

The etiologic agents of haemorragic fever with ranal syndrom (HFRS) in Korea are Hantaan and Seoul virus in the genus Hantavirus, family Bunyaviridae. In order to elucidate the role of maternal immunity to Hantavirus infection in rats, the protective effect of the maternal antibody were studies by using rats experimentally infected with Seoul virus strain HR80-39. Antibody titers of sera and viral antigen against Seoul virus were investigated by indirect immunofluorscence antibody technique (IFA). The dam sera had IFA antibody titers ranging from 1:128 to 1:1,024 after parturition. In fetuses, IFA antibody titers ranged from 1:16 to 1:64 just after birth, increased to peak titers ranged from 1:256 to 1:1,024 in the 2nd week after birth. Challenged newborn rats had IFA antibody titers ranging from 1:64 to 1:1,024 after inoculation. No viral antigen was detected in lungs or other organs of the newborn rats. The maternal antibody to Seoul virus was transferred prenatally through placenta and postnatally via colostrum from immune dams to their offspring. These results demonstrated that maternal antibody to Seoul virus was quite effective in protecting newborn rats against same virus infection.

결장 직장암 환자에서 근치적 절제술 후 혈청 CEA치의 변화에 대한 임상적 의의

김영훈,배병노,김기환,한세환,김홍주,김영덕,김홍용 대한대장항문학회 2003 Annals of Coloproctolgy Vol.19 No.6

Survery of Seroconversion Rates against Hantavirus in Laboratory Rodents

우영대,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2003 Journal of biomedical laboratory sciences Vol.9 No.2

Hantavirus ale rodent-borne RNA virus that belongs to the family Bunyaviridae. Those viruses persistently infect a variety of rodents, and are transmitted by aerosols of their urine, feces and saliva. Antibody titers of sera obtained from normal laboratory rodents against hantavirus were investigated by indirect immunofluorscence antibody technique (IFA). Seroconversion rates of normal laboratory rodents showed higher in rats than that from hamster and mongolian (M), gerbil. Theses rates of normal laboratory rodents also showed higher in titers against puumala virus (PUUV) than in hantaan (HTNV) and seoul virus (SEOV). We are concerned about infections caused by hantaviruses, especially by PUUV, occurred in laboratory rodents.

초등과학 탐구수업 지도자료의 활용 실태

신영준,장명덕,배진호,권난주,여상인,이희순,노석구 한국초등과학교육학회 2005 초등과학교육 Vol.24 No.2

In this study, we had tried to present a plan for improving the actual conditions of practical utilization of teaching material for 6th grade science developed by Ministry of Education & Human Resources Development and distributed to all elementary schools in Korea. Also we presented ways of better utilization of the teaching material after investigating the actual conditions of practical utilization. A survey was made to investigate and collect all data in the major metropolitan cities, the Kangwon, Chungcheong, Honam, and Kyeongsang area, respectively. We surveyed 316 6th grader teachers to investigate the actual conditions of distribution and utilization of teaching material as a general research. In addition, we surveyed 46 teachers to investigate the organization and content of teaching material as a particular research. The results are as follows. First, the teaching material was not approximately transmitted and kept to 6th grader teachers. Second, the utilization guide was not made. Third, it was reported that the thematic divisions of teaching material was a strong point, but the less detailed experiment manual was a weak point. Fourth, the consideration of content difficulties and simplicity was necessary to improve the material. Fifth, additional items should be included in the introductory presentation, convenience of reorganization, activity material causing learning interest, guidance of substitution experiment, and more concrete notice of experiment activity. Finally, there were positive responses of more than 4.0 point of Likert scale (1 to 5 point scale) in detail investigations of thematic items, which could have possibility that the teaching material was helpful to elementary school science field.