원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

발포폴리스티렌비드를 사용한 경량콘크리트의 역학적 특성에 관한 실험적 연구

주재금,이종찬,오세출,유택동,정광량,서치호 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

The purpose of this study is to obtain basic data on the properties of the lightweight concrete within expanded polystyrene beads for various applications in the field. Inquiring into the change of the properties as altering cement matrix mixture and the capacity mixture ratio of expanded polystyrene beads, the mixture plane of this study is set up as W/C is fixed 50%, expanded polystyrene beads is increased 10% from 0% to 80% per 1m³ and the ratio of cement:sand in the cement matrix is 1:0, 1:0.5, 1:1. The results of this study are as follow. The slump as changing the mixture ratio of expanded polystyrene beads decrease smoothly until mixture ratio 50% but decrease rapidly being in excess of 50%. The density decrease regularly as the mixture ratio of expanded polystyrene beads increase but the ratio of strength decrease. The difference of cement matrix. The strength of cement matrix having more sand mixture ratio relatively decrease rapidly as increasing the mixture ratio of expanded polystyrene beads. It is judged decreased strength phenomenon as the quantity of coherent material created in the mixture decrease rapidly.

비장경색이 동반된 쯔쯔가무시병 1예

오종찬,이범주,장재현,원경준,박경희,김동민,박치영,정춘해 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Tsutsugamushi disease is an acute febrile illness caused by Orientie. tsutsugsmushi. It is characterized by fever, myalgia, lymphadenopathy, and rash. And it can be easily diagnosed by characteristic eschar and serologic testing. Nearly all of the patients with tsutsugamushi disease improve with antibiotics such as doxycycline. However, the fatality rate of untreated cases is seven to ten percent. Splenic infarction is not common disease which is caused by occlusion of the main splenic artery or any of its branches. It is mainly caused by emboli that arise from cardiovascular disease, but sometimes by regional thrombosis associated with leukemia, myeloproliferative disorder, sickle cell anemia, pancreatitis, splenic torsion and septicemia. We experienced one case of tsutsugamushi disease with splenic infarction, which was improved after doxycycline treatment finished.

播種期移動에 따른 生育, 收量 및 種實成分의 變化

金鍾喆,吳柱成,鄭大守 東亞大學校 大學院 1997 大學院論文集 Vol.22 No.-

Days to flowering and maturity had a get tendency to be short according as delaying the seeding, the number of pods and 100 seed weight had a tendency to increase by the early seeding, although there were no significant differences of seeding time on the stem length, number of branches, and number of main stem nodes, respectively. Yield of each soybean variety showed the highest value at the plot seeded on 20th June, and the corresponding value was low at the plot seeded on 5th June. Oil contents in both tested soybeans had a tendency to increase according as delaying the seeding, however, proteins showed an increasing tendency according as the earlier seeding date. The contents of histidine, valine, tryptophan, and alanine had also a tendency to increase according as the earlier seeding date. On the contrary, the contents of theronine, methionine, lysine, serine, and proline were respectively increased according as delaying the seeding. The contents of glycine and threonine showed the highest level at the plot seeded on 20the June. Among the contents of minerals in each tested soybean, potassium content was low at the plot seeded on 20th June, although there were no regular tendency of the treatments.

지리산 왕등재 습지의 지표수 수질 및 토양 환경조사

김종오,이창호,지인주 경상대학교 환경보전연구소 2001 環境保全硏究所報 Vol.9 No.-

The this study was performed to survey the characteristics of surface water and soil in Wangdungjae wetland located at Chiri-Mountain. The results of survey summarized as follows; 1. The physico-chemical characteristics of surface water such as pH, temperature, and DO were in the range of 6.02-6.39, 13.5-24.3℃, and 3.81-9.97 ㎎/L, respectively. Also, the organic concentration such as BOD and COD were in the range of 1.3-1.61 ㎎/L and 3.55-0.07 ㎎/L, respectively. The water quality of five different sampling sites showed the similar characteristics. 2. The physico-chemical characteristics of soil showed the different properties with the soil sampling depth. According to increasing sampling depth, cation exchange capacity (CEC) and electric conductivity (EC) increased but pH decreased.

Squalene Adjuvant를 이용한 단백질 항원의 세포성 면역반응 유도

도현주,김성열,안종성,하영주,이승찬,오재택,장명호,정홍석,문홍모,박해준 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.3

To investigate the role of adjuvant for cytotoxic T lymphocytes (CTL) induction, squalene-based adjuvant was studied its capability eliciting to the induction of cellular immunity as well as humoral immunity to exogeneous proteins. Ovalbumin (OVA) was used as model proteins. It was demonstrated that antigen formulation consisted of metabolizable oil squalene mixed with Tween 80 and pluronic L121 (S/TJ121) could induced the antigen specific CTL responses and antibodies irrespective of immunization routes in mice. We also demonstrated that this antigen formulation was a inducer of CD8+, major histocompatibility complex(MHC) class I-restricted, and antigen-specific C;1'Ls. These data suggest that the squalene-based emulsion system is a potent adjuvant inducing cellular immunity as well as humoral immunity.

암반사면의 안정성 검토에 관한 연구

안종필,박주원,오수동 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.3

In general the evaluation process of rock slope stability is an ambiguous system which is made up of ideas subjected to practical experience of an expert. This paper aims to propose more effective methods that helps engineers to evaluate the stability of rock slope by using RMR(Rock Mass Rating for the Geomechanics Classification) and Stereo-graphic Projection and Fuzzy Approximate Reasoning Concept. The result of this paper is that a rational evaluation of rock slope stability and countermeasures can be achieved through RMR and Stereo-graphic Projection and Fuzzy Approximate Reasoning Concept.

水盜作에서 親環境農業 定着을 위한 오리 및 왕우렁이 農法의 可能性 分析

이종성,김기영,황필성,오주성,정원복,정순재 동아대학교 농업생명과학연구소 2001 農業生命資援硏究 Vol.10 No.1

Concerns on use of excess amount of chemical fertilizer and pesticide in current farming system turns both of the producer and consumer of agricultural products to an organic farming which use a less chemicals and more natural manure. Possibility Analysis of Pond-snail and Duck Faming for Environment-friendly Agriculture in paddy field. Depression effect of weed occurrence by pasture of 5kg of the Pond-snail(Ampullarius insularus) per 10a and the 7th day after transplanting. Optimum duck rasing density in rice paddy field was was 25~30 heads per 10a and ducks could be harvested three times in a year starting from 40 days after mature-seedling machine transplanting. The weed control rate of the duck raised paddy field was superior to the conventional agriculture. Yield per 10a of the duck raised and pond-snail(Ampullarius insularus) farming was inferior to conventional agriculture. The earnings of The Duck and Pond-snail farming realize a profit. From these results, it seems that the Organic farming are usefel and pasture of the Duck, Pond-snail(Ampullarius insularus) for depression of the weed occurrence is effective as the environmental perservation farming.

유기농 자재의 시용이 토양의 이화학적 성질과 상추, 가지의 생육 및 체내성분에 미치는 영향

이종성,김기영,황필성,오주성,정원복,정순재 동아대학교 2001 大學院論文集 Vol.26 No.-

This study was carried out to investigate the effect of microbial fertilizers on the application of organic farming materials in soil on growth and yields of leaf lettuce, eggplant. Three microbial fertilizers, Aika, Kalen-gold and EMRO-EM were used. The results were summarized as follows ; 1. The effect of soil chemical properties after application organic arming materials, The amounts of pH, EC, P2O5 and O.M. treated all plot were few of change. 2. Change of soil microbial after application organic farming materials, The number of bacteria, actinomycetes and fungi in N, P, K treated plot showed the increased tendency, to the contrary, The number of bacteria, actimycetes in Aika, kalen-gold and EMRO-EM treated plot showed the increased, The number of fungi showed the dicreased tendency 3. The application effects of Aika, Kalen-gold and EMRO-EM on the growth, yield and components of leaf lettuce and eggplant in comparison with chemical fertilizers plot was not a difference.

법랑모세포 분화와 법랑질 형성과정에서 OD314, Apin protein의 발현 및 기능

박종태,최용석,김흥중,정문진,오현주,신인철,박주철,손호현 대한치과보존학회 2006 Restorative Dentistry & Endodontics Vol.31 No.6

본 연구에서는 법랑모세포 분화와 법랑질 형성에 연관이 있는 OD314 일명 Apin protein의 기능을 밝힐 목적으로, in-situ hybridization에 의한 OD314 mRNA 발현과 법랑모세포 세포주에서 OD314 enamel matrix protein의 발현, 그리고 OD314 유전자를 과발현/억제시킬 수 있는 construct를 제작한 후 법랑질 형성 중에 OD314의 기능을 알아보고자 RT-PCR를 시행하여 다음과 같은 결과를 얻었다. 1. OD314 mRNA는 발생중인 상아모세포보다 법랑모세포에서 강하게 발현되었다. 2. Tuftelin은 석회화 결정이 형성되는 14일까지 발현이 지속되고, 그 이후부터 점차 감소하였다. Amelogenin과enamelin은 7일부터 그 발현이 점점 감소하였다. 3. U6-OD314 siRNA construct를 이용하여 transfection한 법랑모세포 세포주는 OD314와 tuftelin,MMP2 mRNA 발현이 감소하였으며, CM-OD314를 transfection하여 OD314의 과발현을 유도한 경우에는 OD314와 MMP20 mRNA의 발현이 뚜렷이 증대되었다. 이 결과는 OD314가 법랑모세포의 분화와 법랑질의 형성 그리고 석회화 과정에 중요한 역할을 하는 새로운 인자임을 시사한다. This study was aimed to elucidate the biological function of OD314 (Apin protein), which is related to ameloblast differentiation and amelogenesis. Apin protein, calcifying epithelial odontogenic (pindborg) tumors (CEOTs)-associated amyloid, were isolated from CEOTs, and has similar nucleotide sequences to OD314. We examined expression of the OD314 mRNA using in-situ hybridization during tooth development in mice. Expression of OD314 and several enamel matrix proteins were examined in the cultured ameloblast cell line up to 28 days by reverse transcription-polymerase chain reaction (RT-PCR) amplification. After inactivation and over-expression of the OD314 gene in ameloblast cell lines using U6 vector-driven RNA interference and CMV-OD314 construct, RT-PCR were performed to evaluate the effect of the OD314 during amelogenesis. The results were as follows: 1. In in-situ hybridization, OD314 mRNAs were more strongly expressed in ameloblast than odontoblast. 2. When ameloblast cells were cultured in the differentiation and mineralization medium for 28 days, the tuftelin mRNA expression was maintained from the beginning to day 14, and then gradually decreased to day 28. The expressions of amelogenin and enamelin were gradually decreased according to the ameloblast differentiation. 3. Inactivation of OD314 by U6-OD314 siRNA construct down-regulated the expression of OD314, MMP-20, and tuftelin, whereas over-expression of OD314 by CMV-OD314 construct up-regulated the expression of OD314 and MMP-20 without change in tuftelin. These results suggest that OD314 is considered as an ameloblast-enriched gene and may play the important roles in ameloblast differentiation and mineralization.