(±)-Camphor가 ICR 마우스 수컷의 간 cytochrome P450 효소 활성에 미치는 영향

오은경,박형건,배기현,최옥진,최은경,최창근,한진희,정태천 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

Effects of (±)-camphor on liver cytochrome P450 enzymes were investigated in male ICR mice. Mice were treated intraperitoneally with 0, 200, 400 and 800 mg/kg of (±) -camphor in corn oil for 3 consecutive days. Twenty four hr after the final treatment, the animals were subjected to necropsy. The activities of serum aspartate aminotransferase and serum alanine aminotransferase were slightly changed by the treatment with (±)-camphor at the doses used. Administration o(±)-camphor to mice significantly induced the hepatic activities of pentoxyresorufin O-depentylase and benzyloxyresorufin O-debenzylase and weakly induced ethoxyresorufin O-deethylase in dose-dependent manners. The present results suggested that (±)-camphor might act as a relatively specific inducer of hepatic cytochrome P450 213 in male ICR mice.

Scanning tunneling microscopy investigation of nano-structured α-K5PW11(M x OH2)O39(M = Mn(II), Co(II), Ni(II), and Zn(II)) Keggin heteropolyacid catalyst monolayers.

Choi, Jung Ho,Kang, Tae Hun,Bang, Yongju,Yoo, Jaekyeong,Jun, Jin Oh,Song, In Kyu American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.11

<P>Nano-structured α-K5PW11(M x OH2)O39 (M = Mn(II), Co(II), Ni(II), and Zn(II)) Keggin heteropolyacids (HPAs) were investigated by scanning tunneling microscopy (STM) and tunneling spectroscopy (TS) measurements in order to elucidate their redox property and oxidation catalysis. HPA molecules formed two-dimensional self-assembled monolayer arrays on highly oriented pyrolytic graphite (HOPG) surface. Furthermore, HPAs exhibited a distinctive current-voltage behavior referred to as negative differential resistance (NDR) phenomenon. The measured NDR peak voltage of HPAs was correlated with the reduction potential and the absorption edge energy determined by electrochemical method and UV-visible spectroscopy, respectively. NDR peak voltage of HPAs appeared at less negative voltage with increasing reduction potential and with decreasing UV-visible absorption edge energy. The correlations strongly suggested that NDR phenomenon was closely related to the redox property of HPAs. Vapor-phase oxidation of benzyl alcohol to benzaldehyde was carried out as a model reaction to track the oxidation catalysis of HPAs. NDR peak voltage appeared at less negative voltage with increasing yield for benzaldehyde.</P>

2007년 대한감염학회 권장 성인 예방접종 권장안

강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

모바일 벡터 지도 서비스 환경을 위한 공간 데이터 압축 기법

최진오 부산 외국어 대학교 2004 外大論叢 Vol.28 No.-

According to the rapid advance of computer and communication techniques, the request of mobile internet services is highly increasing. However, the main obstacles for mobile vector map service environments, are large data volume and narrow wireless bandwidth. Among the many possible solutions, spatial data compression technique may contribute to reduce the load of bandwidth and client response time. This thesis proposes two methods for spatial data compression. The one is relative coordinates transformation method, and the other is client coordinates transformation method. And, this thesis also proposes the system architecture for experiments. The two compression methods could be evaluated the compression effect and the response time.

불국사 석탑의 물성 및 지반특성 조사

최희수,서만철,오진용 공주대학교 문화재보존과학연구소 2003 문화재과학기술 Vol.2 No.1

경주 불국사의 다보탑과 석가탑은 751년에 축조된 국보급 문화재이나 오늘날은 석재의 풍화 및 지대석의 어긋남 현상들이 관찰된다. 이에 대한 정확한 이해는 두 석탑의 안정성 진단에 필수적이며 따라서 석탑의 지반환경과 석재 물성에 관한 비파괴 정밀 조사가 필요로 한다. 이 연구에서는 석재의 역학적 성질을 위해 초음파 속도 측정을 실시하였고 천부지질구조를 위해 탄성파, 전기비저항, 지하레이더 등의 비파괴 복합 지구물리탐사를 석탑 주변에서 수행하였다. 초음파 속도범위는 석가탑에서는 1217~4403 m/s이며, 다보탑에서는 584~5845 m/s이며 이로부터 추정한 일축강도 평균치는 각각 463 kg/cm^(2), 409 kg/cm^(2)이다. 대체로 두 석탑 주변의 북서쪽 구역에서 낮은 탄성파 속도와 비저항 값이 나타나, 이 부분을 비교적 연약한 지반으로 해석한다. 그리고, 탄성파 속도분포에서는 다보탑 지반이 더 큰 속도를 보여 상대적으로 석가탑 지반보다 견고함을 보여준다. 대체로 석탑지반의 전기비저항은 최대 2200 Ωm이며 200 Ωm내외의 외부지반보다 더 높은 값을 보인다. 복합 지구물리탐사 결과를 종합하면 다보탑지반의 형태는 8각형(한 변은 6 m)으로 그 깊이는 약 4 m 이나, 석가탑지반은 약 8x10 m의 직사각형 형태로 깊이는 약 3 m 이다. Two three-story stone pagodas, Seokgatap and Dabotap, built in 791 at Bulkuksa temple, are well-known national treasures. However, they have experienced weathering process and an offset of the stone alignment is observed at the base part of Dabotap. Understanding of these phenomena is essential for the structural safety diagnosis for them, and therefore the nondestructive geophysical methods was applied. Direct measurements of ultrasonic velocities was introduced for the mechanical properties of the stone. Multidisciplinary geophysical prospectings including seismic, resistivity, ground-penetrating radar(GPR) methods were carried out around two pagodas for their site characteristics. The velocity ranges of ultrasonic waves for Dabotap and Seokgatap are 1217~4403m/s and 584~5845m/s, respectively, and the estimated averages of the uniaxial compressive strength are 463 kg/cm^(2) and 409 kg/cm^(2), respectively. At the northeast of each pagodas, the lower seismic velocities and resistivities are shown, which is interpreted to be weaker subsurface section. On the basis of the higher velocity structure, the site of Seokgatap appears to have solider stability than the Seokgatap site. Near the pagodas, higher(up to 2200 Ωm) resistivity is present whereas their outskirts have as low as 200 Ωm. By the combined results of each geophyscial methods, the subsurface boundaries of each stone pagodas are revealed. The Dabotap site is in the form of an octagon having 6-m-long side with the depth of ~4 m, whereas the Seokgatap site is the 8x10 m rectangle with the depth of 3 m.

무선 인터넷 환경에서 동적 지도 생성을 위한 Generalization 기법

최진오 부산 외국어 대학교 2001 外大論叢 Vol.22 No.1

According to the rapid advance of computer and communication technique, the request of mobile internet services is highly increasing.However, the current level of mobile web technique could not satisfy all the services, as the wired internet ones.Mobile map service is one of the examples.Spatial data have very large data volume, thus, it takes large resource of client machine to display and store the map which is transferred from the server.It requires also large bandwidth to transfer the data to client.The main obstacle of wireless environment is small bandwidth and often loss of connection.Thus, the study of reducing the data volume to transfer is required. This paper deals with the method to reduce the volume of spatial data at server for mobile map service.This paper proposes the new generalization scheme which endures the dynamic environment change of bandwidth.Predefined generalization plans are evaluated at run-time by generalization constraint to pick up best one.

4세 유아에 발생한 몰입성 하마종(plunging ranula); 증례보고

최진호,양동환,김일규,오남식 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.4

Whereas oral ranula is relatively common and presents as a cyst in the mouth, the plunging ranula is rare and manifests itself as a mass in the neck with or without an associated oral lesion. When there is a soft anterior neck swelling without oral swelling, diagnosis is still difficult. In such a case, clinical suspicion may be low and the pathologist may be misled by the histologic appearance. Recognition of the diagnosis of plunging ranula is essential for the correct treatment of these lesions We report a case of a 4-year-old girl and review the literatures to discuss the differential diagnosis and treatment modalities.

발작성상심실성 빈맥환자에서 Adenosine과 Verapamil의 치료효과

최성욱,오진호,김승호 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3

Background. According to the 1992 version of ACLS guideline, adenosine is recommended as the first line drug for the treatment of paroxysmal supraventricular tachycardia(PSVT). But adenosine is not used frequently in our country, despite currently proven effect and safety. Therefore we tried to compare the efficacy and safety of adenosine with verapamil for the treatment for PSVT. Materials and Methods. We prospectively reviewed charts of PSVT patients admitted to YongDong Severance Hospital from Jan. 1995 to Dec. 1996. These patients were randomly divided into two groups. The first group was given 6mg of adenosine initially , and another 12mg was given within 5minutes if first dose failed. The other group was given 5mg of verapamil initially, and if failed, 10mg was given within 10minutes. The results were analyzed by Chi-square test and student- t method Results. In converting PSVT to normal rhythm, adenosine and verapamil showed similar results and there was no difference between the two groups in frequency of side effects, but serious arrhythmia such as ventricular fibrillation and ventricular tachycardia was not seen in the adenosine group. Conclusion. Adenosine not only showed comparable effect and safety, but also had shorter action time than verapamil. Therefore we recommand sdenosine, as a safe and effective first line drug for PSVT.

食餌 脂肪質의 不飽化/飽化脂肪酸 比率이 흰쥐의 리포단백 콜레스테롤의 含量에 미치는 影響

崔鎭浩,金一星,金在一,朴泉洙,尹泰憲,吳成基 한국노화학회 1992 한국노화학회지 Vol.2 No.1

食餌 脂肪質의 不飽化/飽化脂肪酸 比率이 흰쥐의 肝臟 細胞膜의 脂質組成에 미치는 影響

崔鎭浩,金一星,金在一,朴泉洙,尹泰憲,吳成基 한국노화학회 1992 한국노화학회지 Vol.2 No.1