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      • 交通安全施設 投資政策에 關한 硏究

        尹正吉,洪昌義,金萬培 建國大學校 社會科學硏究所 1997 社會科學論叢 Vol.2 No.-

        ■Background and purpose Traffic safety facilities is an important tool that it is contribute to traffic flow and safety instead of the roles of a traffic police or maneger in road. The current system for road traffic safety related facilities management is not in a satisfactory state, and more efficient system, therefore, is needed for the policy makers, researchers, and other people. This paper is to analyze the problem in the current system and to make suggestion to establish more efficient system. ■Contents · Analysis of the present road traffic safety facilities management system. - Functional allocation, financial resources, and future demand cost forecast · Case study in Japan. - Comparative analysis between Korea and Japan · Development of road traffic safety facilities management system. - Principles and alternatives for financial resources and functional allocation between central and local government ■Conclusions Traffic safety facilities should be maintained in the current system, in order to enhance operational capacity, secured proffessional manpower and utilized the third sector or RTSA(Road Traffic Safety Association). Also the future traffci safety facilities investment cost is to forecasted 3,400 hundred million won in the 2000 year, therefore is needed financial resources in centural government. In order to secure investment resources for traffic safety facilities should be given improvement plan of special account law

      • 도로 종류별 안전도에 관한 연구 : 고속도로와 국도를 중심으로 Focussing the express highway and the national road

        윤정길,홍창의,김만배 건국대학교 사회과학연구소 2000 社會科學論叢 Vol.24 No.-

        The paper aims to compare the safety between highway and the national road in South Korea. I first of all,we will try to evaluate the accident rates by VEK(vehicle kilometers traveled) for the express highway and for the national road.All things being equal,each accident rate will tell which road is more safe. For the result of this paper, the accident rate, fatal rate, inury rate of the national road are respectively 4.5 times,2.0 times,3 times as hogh as that of express highway. In conclusion, the express highway is more safe than the national road though our method.

      • Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

        Park*, Eui,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung,Sik,Kim, Yun,Jeong,Park, Young‐,Mee,Park, Eun,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

        <P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

      • KCI등재

        열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

        배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

        Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

      • KCI등재

        경계요소법에 의한 이종재료 접합 잔류열응력의 해석

        유영철,이 원,윤인식,정의섭 韓國非破壞檢査學會 1995 한국비파괴검사학회지 Vol.15 No.4

        전자 부품의 일종인 LSI 패키지의 제조 과정에서 절연·방진·방습 등을 목적으로 수지 몰딩이 널리 사용되고 있는데, 냉각과정에서 금속과 수지의 계면에 접합 잔류열응력이 발생하여 파괴의 원인이 되고 있다. 접합 잔류열응력의 측정에는 X선 회절법등이 사용되지만 측정상의 어려움과 계면단 응력특이성에 대한 해석의 곤란함 때문에 적절한 모델링에 따른 수치해석적 연구가 새로이 주목을 받고 있다. 본 연구에서는 Al/Epoxy를 몰딩 접합한 세가지의 대표적인 계면 형상을 선정하여 계면에서의 잔류열응력을 경계요소 수치 해석 및 스트레인 게이지를 이용한 실험을 통하여 각각 해석하였다. 수치해석과 실험결과는 정상적으로 잘 일치하였으며, 서브 요소를 사용하므로써 계면단 응력 특이성의 해석 정밀도를 향상시킬 수 있었다. 또한 접합 잔류열응력의 해석결과로부터 수직응력에 의한 계면 박리가 예상되고, 피착체의 두께가 증가할수록 응력 특이성이 강하게 나타남을 확인하였다. In general residual stress is measured by X-ray diffraction method but in case of bonding residual thermal stress it is inadequate technique to examine the stress singularity. Therefore Two-dimensional elastic boundary element analyses were carried out to investigate the residual thermal stress and stress singularity of bonding interface in Al/Epoxy. This boundary element results were compared with the strain gauge measurements. The effects of different interface models, sub-elements and adherend thickness are presented and discussed. On the basis of the obtained results, interface delamination causing by normal stress is expected and stress singularity is observed more intensively increasing with adherend thickness. It is concluded that the bonding strength of Al/Epoxy interface can be estimated correctly by taking into account the stress singularity at the edge of the interface.

      • P191 The clinicopathologic study of multiple dermatofibroma

        ( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

        <div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Dermatofibromas are common, benign, painless dermal nodules. Although cases of solitary dermatofibromas are common, multiple dermatofibromas are rare and there is no explainable theory in healthy people. Objectives: This study was conducted to obtain better understanding of the clinicopathologic features of multiple dermatofibroma. Methods: This is a retrospective study of multiple dermatofibroma pathologically diagnosed at our hospital over a 12-year period (2004~2015). Clinicopathologic features of 22 patients, 108 lesions were evaluated. The sex, age, number of lesions, site, symptoms and histopathological finding are included. Results: Of the 22 patients, sixteen (72.7%) were female and six (27.3%) were male. mean age was 39.1(±11.5) years old. The number of lesions ranged 2 to 20 and the mean was 4.9. The most common predilection sites were lower extremities (42.6%). All cases treated by excisional biopsy. According to the histopathological finding, the most common histological subtype was fibrocollagenous (66.7%). Most of the cases were extended dermis (62.5%) layer. Mitotic activity was not definite in majority of cases. The major infiltrated inflammatory cells were lymphocyte (75.2%). Conclusion: Multiple and solitary dermatofibroma have clinical and pathological consistency except for numbers of lesions.

      • P097 A clinical investigation of cutaneous malignant tumors in western Gyeongnam province over 11 years

        ( Yun Sun Moon ),( Jeong Won Jo ),( Hae Bong Jeong ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

        <div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: The incidence rates of cutaneous malignant tumors in the Korean population are increasing. However, few clinical studies have been conducted on cutaneous malignant tumors in Gyeongnam Province. Objectives: The purpose of this study was to evaluate the prevalence of cutaneous malignant tumors in Western Gyeongnam Province and to compare the results with previous reports of cutaneous malignant tumors. Methods: We retrospectively reviewed 46,277 outpatients who visited the Department of Dermatology from 2005 to 2015. Among them, 1,120 patients who underwent biopsy for skin tumors had tumors classified as cutaneous malignant tumors. We compared the histopathological diagnoses and analyzed the distribution of dermatologic diseases and clinical features, including age and sex. Results: The mean age of the patients was 70.0 years. The ratio of male to female patients was 1:1.85. Cutaneous malignant and premalignant tumors were found in 2.4% of all new patients. The most common disease was basal cell carcinoma (39.6%), followed by squamous cell carcinoma (31.5%), malignant lymphoma (6.3%). The most common premalignant tumor was actinic keratosis (73.2%), followed by Bowen’s disease (26.8%). The most common site of cutaneous malignant tumors and premalignant tumors was the face (75.3% and 80.8%). Conclusion: This study provides useful data on the incidence and characteristics of cutaneous malignant tumors. The frequency of malignant tumors was higher than previous studies.

      • P064 The effect of excess caffeine exposure on human umbilical vein endothelial cells and head and neck squamous cell carcinoma

        ( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

        <div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Caffeine intake and consumption of coffee were estimated from food frequency questionnaires results these are increasing. Caffeine may repair skin damage induced by excessive exposure to ultraviolet light. In previous report of the associations between coffee consumption and incidence of these skin cancers, the result that the consumption of neither caffeinated nor decaffeinated coffee was associated with basal cell carcinoma and squamous cell carcinoma (SCC). Objectives: In this study, our aim is to describe the mechanisms of the anti-angiogenic effect of caffeine in human umbilical vein endothelial cells (HUVECs) and head and neck squamous cell carcinoma (HNSCC). Methods: Matrigel assays were used to investigate the effect of caffeine on angiogenesis at cell migration and wound healing and proliferation assays using HUVECs and HNSCC. Results: Caffeine was found to inhibit blood vessel formation dose-dependently and to inhibit the proliferation of HUVECs time- and dose-dependently. The apoptosis examination was used by western blotting and immunofluorescence staining. Conclusion: Caffeine was found to inhibit blood vessel formation dose-dependently and to inhibit the proliferation of HUVECs on the same manners. There is no satisfactory enhancement and/or inhibition on proliferation of HNSCC.

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