김치의 혈전용해작용

강정옥,정영기,김정옥,양웅석,공인수 동의대학교 기초과학연구소 1996 基礎科學硏究論文集 Vol.6 No.1

Fibrinolytic activity of fermented kimchi and ingredients used for the preparation were assayed by measuring the lysis area on plasminogen-rich fibrin plate. Fermented kimchi and pickled fish sauces from changlan, prwan, and anchovy showed the activity, and the activity of pickled fish sauces were high in the order of pickled changlan, pickled anchovy(pickled mulchi), and pickled prawn. However, the activity of kimchi may not be attributed to pickled fish sauce because kimchi containing fish sauce did not possess activities before fermentation. To investigate fibrinolytic agents in the kimchi if protein, the activities were determined from the samples heated for 30min at 100℃. There was no changes in the activities before and after heat treatment indicating the agents may be components other than protein. Since major changes occur during kimchi fermentation were increased sour taste due to production of organic acids such as lactic, citric, oxalic, and succinic acids, the authentic organic acids present were examined for fibrinolytic activities. The results indicates that the major component posses the activity is lactic acid.

保險事故發生前의 保險給付請求權의 讓渡

鄭鎭玉,鄭容相 釜山 外國語 大學校 1998 外大論叢 Vol.18 No.2

Die vorliegende Arbeit befaβt sich mit den interessenkonflikten, die sich dann ergeben konnen, wenn der Versicherungsnehmer Rechte und Asnpruche aus einem Lebensversicherungsvertrag auf einen Dritten Ubertragt im Rahmen einer Sicherungszession oder Vollzession. Es soll hierbei nicht nur untersucht werden, weiche Voraussetzungen fur eine wirksame Abtretung vorliegen mussen, sondern vielmehr auch die Rechtsposition der Beteiligten nach erfolgter Abtretung dargestellt werden. Im Rahmen der jeweiligen Interessenkonflikte wird die Rechtslage bei der Versicherung mit unwiderruflicher und widerruflicher Begunstigung dargelegt. Der Versicherungsnehmer kann einen zu seinen Lebzeiten auftretenden Geldbedarf durch Ruckgriff auf den Zeitwert seiner Lebensversicherung nur befriedigen, wenn er sich deren Spar-bzw. Kreditsicherungsfunktion zunutze machen kann. Die Vorschrift des §731Abs. 2 Koreanischen Handelsgesetz setzt voraus. daβer imstande ist, die vertraglichen Gestaltungsrechte auszuuben bzw. uber die geldwerten Versicherungsanspruche durch Abtretung frei zu verfugen. Diesem interesse des Versicherungsnehmers an freier Negoziabilitat widerstreitet das interesse des Begunstigten, bei Eintritt des Versicherungdfalls in den Genuβder versicherungssumme zu gelangen. Die Durchsetzung dieses Versorgungsinteresses erfordert eine durch Abtretung des Versicherungsnechmers nicht zu beeintrachtigende Rechtsposition des Dritten. Im Arbeit wird erortert, ob und inwieweit die Rechtsposition des Begunstigten durch die Abtretung von Rechte und Anspruche aus einem Lebensversicherungsvertrag eingeschrankt wird. In Hinblick auf die Frage, welche Voraussetzungen fur eine wirksame Abtretung vorliegen mussen, eine Abtretung der Versicherungsanspuche ist dem versicherer gegenuber nur erst dann wirksam, wenn sie der Verfugungsberechtigte angezeigt hat. Die Rechtsfolgen einer Anzeige der Abtretung regelt die Vorschrift des §450 Koreanischen BGB. Keine Ubergabe des Versicherungsscheines verlangt fur die Wirksamkeit der Abtretung. Fur die Frage, wie die Abtretung des Versicherungsanspruches druch den Versicherungsnehmer auf die Rechtsstellung auswirkt, ist zwischen Vollzession und Sicherungsabvtretung, zu unterscheiden. Bei der Vollzession im Gegensatz zur Sicherungszession soll dem zessionar nach dem Willen der Parteien die eingeschankte Glaubigerstellung hinsichtlich der Versicherungsleistung zugewendet werden, weil die dem Versicherer anzuzeigende Abtretung regelmaβig den endgunstigung beinhaltet. Nach meiner Meinung geht dergegenuber davon aus, auch die Sicherungszession einen widerruf der Bezugsberechtigung bedeutet und daβdieser Widerruf mit Anzeige bei dem Versicherer wirksam wird, ohne daβ insoweit eine ausdruckliche Erklarung uber den Widerruf der Bezugsberechtigung abzugeben ist. Eine ganz andrere und noch weitergehende Frage ist es, ob die Sicherungszession einen endgultigen Widrruf der Bezugsberechtigung enthalt oder ob der Widerruf nur fur die Dauer der Abtretung wieder auflebt. Anders als bei der Vollzession ist mit der Sicherungszession regelmabig kein endgultige Widerruf der Bezugsberechtigung verbunden, vielmehr ist davon auszugehen, dab nach erfolgter Ruckabtretung das ursprunglich Bezugsrecht wieder auflebt. Sofern der Versicherungsnehmer fur die Leistung im Erlebens oder im Todefall unwiderruflich einen Bezugsberechtigten bezeichnet hat, erwirbt dieser bereits mit der Benennung ohne weiteres Zutun den Anspruch gegen den Versicherer.

토양 표면의 전기화학적 특성과 응용

옥용식,임수길,김정규 고려대학교 생명자원연구소 2002 생명자원연구 Vol.10 No.-

마취유도시 기관내 삽관에 대한 분석

정재용,신옥영,권무일,김동수 경희대학교 1997 慶熙醫學 Vol.13 No.2

양친매성 유기점토를 이용한 중금속과 유기 오염물질 동시제거 기술

옥용식,임수길,김정규 한국환경농학회 2003 한국환경농학회지 Vol.22 No.3

Although clay can sorb significant amounts of inorganic contaminants from soils and waste-water, the hydration of exchangeable cations in clay minerals makes it hydrophilic at the clay mineral surfaces and interlayers. Thus, natural clays are often ineffective in complexing and stabilizing toxic organic contaminants in soils and groundwater environment. But, substituting these hydrated cations with cationic surfactant such as QAC(Quaternary ammonium Compound) can change the natural clay from hydrophilic to hydropobic. Furthermore functionalized organoclay can act as a powerful dual function sorbent for both toxic metals and organic compounds. It also can be used as landfill clay liners, slurry walls, nano-composite materials, petroleum tank farms, waste treatment, and fflter systems. To use this modified clay minerals effectively, it is required to understand the fundamental chemistry of organoclay, synthetic procedures, its engineering application, bioavailability of sorbed ion-clay complex, and potential risk of organoclay. In this review, we investigate the use, application and historical background of the organoclay in remediation technology. The state-of-the-art of organoclay research is also discussed. Finally, we suggest some future implications of organoclay in environmental research.

구조적 손상을 입은 철근콘크리트 보의 보강 효과에 관한 연구

김정섭,신용석,김경옥 朝鮮大學校 建設技術硏究所 2006 建設技術硏究 Vol.26 No.1

This study conducted bending experiment to examine reinforcing effects after preloading of reinforced concrete by reinforcing materials and obtained the following conclusions. To sum up experimental results, it was found that CFS reinforced specimens were excellent in improving bending force and ductility capacity and CB reinforced specimen showed higher reinforcing effects. GFS reinforced specimen had lower reinforcing effects due to lower attachment than fiber reinforced material CFS. GSP reinforced specimen had larger internal force than other reinforced specimens, but it showed the lowest reinforce effects due to its low attachment to concrete and GSP reinforcing specimen showed the same or higher reinforcing effects than other reinforcing materials if its attachment to concrete is improved.

기존 골조공사공법과 복합화구조공법의 작업생산성 및 공사비 비교분석에 관한 사례연구

김정재,박옥근,김용수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

The purpose of this study is to provide productivity(man-hour) and cost comparison among conventional structural methods(Reinforced concrete structure and Steel structure) and new structure methods(HI-Beam and LC-Frame) in office buildings. Productivity and cost analysis were performed based on data collection in construction sites and interview survey. The results of this study are as follows: comprehensive productive and cost efficiency is investigated as high from (1)LC-frame, (2)HI-Beam, (3)steel structure, and reinforced concrete in order.

이행성 협심증 환자에서 운동부하 심전도 검사

이정우,박형서,박용규,노상필,이유선,정승현,김보영,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

목적 : 관상동맥의 경련에 의한 이형성 협심증환자에 있어서 운동부하 심전도 검사의 결과는 매우 다양하다. 이에 저자들은 충남대학교병원 순환기내과에서 관상동맥조영술상 이형성 협심증으로 확진된 환자를 대상으로 운동부하 심전도 검사를 시행하여 이에 대한 결과를 연구하였다. 방법 : 1995년 1월부터 2002년 3월까지 흉통을 주소로 충남대학교병원 순환기 내과에 입원하여 관상동맥조영술을 시행하여 관상동맥의 내경이 50% 미만의 협착이 있고, 에르고노빈(ergonovine) 유발검사도 이형성 협심증으로 진단을 받은 233명중 운동부하 심전도 검사를 시행 받은 183명의 환자를 연구 대상으로 하였다. 운동부하 심전도 검사 결과의 판독시 발생할 수 있는 오류를 줄이기 위해서 운동부하 심전도 검사를 시행하기전 심전도상 ST분절의 상승(5예)이나 하강(8예)이 있는 경우 EH한 T파의 역위(19예)가 있는 32명의 환자를 제외한 총 151명의 환자를 대상으로 하였다. 운동부하는 Marquette사의 case 15 답차를 이용하였고, Bruce protocol에 따라 증상이 나타날 때까지 최대로 실시하였으며 각 stage 및 운동후의 혈압을 측정하고 12 유도 심전도를 기록하였다. 결과 : 1) 임상적 특성 - 내원시 임상 상은 안정형 협심증이 39예(25.8%), 불안정형 협심증이 103예(68.2%), 심근경색증이 9예(6.0%)이었다. 운동부하 심전도 검사 결과 양성 군과 음성군간에 있어서 당뇨병, 고혈압, 비만도, 총 혈청콜레스테롤치, 현재의 흡연 여부, 병력상 운동시 흉통의 유무, 내원시 임상적 진단, 협착의 정도, 연축의 수 등을 조사하였는 바 어떠한 인자들도 유의한 차이를 발견할 수 없었다. 2) 운동부하 심전도 검사 - 운동부하 심전도 검사를 시행 받은 151명의 환자중 음성인 경우는 134예(88.8%)이었고, 양성인 경우는 17예(11.2%)이었다. 양성 소견을 보인 환자들중 ST 분절의 상승이 4예(2.6%), ST 분절의 하강이 13예(8.6%)이었다. 3) 관상동맥조영술 - 관상동맥조영술상에서 혈관 경력 위치는 우관상동맥이 70예(46.1%), 좌전하동맥이 44예(28.9%), 좌회선동맥이 17예(11.2%)의 순으로 나타났다. 운동부하 심전도 검사상 ST 분절의 상승이 있었던 예중 Ⅱ, Ⅲ, aVF에서 ST 분절의 상승이 있었던 1예는 관상 동맥조영술상 우관상동맥에서 경련이 발생하였고, V2-V4에서 ST 분절의 상승이 있었던 2예중 관상동맥조영술상에도 좌전하행동맥에서 경련이 나타난 예는 1예이었으며 다른 1예는 좌회선동맥에서 경련이 나타났고, V5-V6에서 ST 분절의 상승이 있었던 1예는 관상동맥조영술상에도 좌회선동맥에서 경련이 나타났다. 운동부하 심전도 검사상 V5 또는 V6에서 ST 분절의 하강이 있엇던 13예중 6예(46.1%)는 관상동맥조영술상 우관상동맥에서 경련이 발생하였고, 3예(23.1%)는 좌전하행동맥에서, 1예(7.7%)는 좌회선동맥에서, 나머지 3예(23.1%)는 2개의 혈관이나 기타 분지에서 경련이 발생하였다. 결론 : 1) 이형성 협심증 환자는 운동부하 심전도 검사에서 11.2%의 양성소견을 보였다. 이중 ST 분절의 상승은 2.6%이었고, ST 분절의 하강은 8.6%이었다. 2) 이형성 환자중 운동부하 심전도 검사를 실시하여 음성을 보이는 경우 다혈관 관상동맥질환이기 보다는 이형성 협심증일 가능성이 더 높다고 예측할 수 있을 것으로 생각된다. 3) 이형성 협심증 환자중 운동부하 심전도 검사를 실시하여 ST 분절의 상승을 보이는 경우 다혈관 관상동맥질환이기 보다는 이형성 협심증일 가능성이 더 높다고 예측할 수 있을 것으로 생각된다. 4) 운동부하 심전도 검사 결과에 대한 당뇨병, 고혈압, 비만도, 총 혈청콜레스테롤치, 현재의 흡연여부, 병력상 운동시 흉통의 유무, 내원시 임상적 진단, 협착의 정도 등 어떠한 인자들도 3그룹(ST 분절의 상승, ST 분절의 하강, 음성)간에 유의한 차이를 발견할 수 없었다. 5) ST 분절의 상승 부위와 관상동맥조영술상 관상동맥의 연축이 일어나는 혈관과의 상관관계는 매우 높았다. No reports in the literature describe the results of exercise testings in a large number of patients with pure variant angina(coronary stenosis <50%) in Korea. In this report, We present the results of treadmil exercise testing in 151 patients with variant angina. 151 patients with angiographically proven coronary artery spasm underwent a treadmil exercise test. The clinical characteristics of variant angina patients classified according to ST-segment response to exercise were analyzed. Of 151 patients underwent a treadmil exercise test, negative result was seen in 134 patients(88.8%) and positive result was in 17 patients(11.2%). Of 17 patients saw positive result, exercise-induced ST segment elevation was present in 4 patients(2.6%) and ST segment depression was seen in 13 patients(8.6%). There was not a significant relationship between the ST segment response to exercise and the clinical variables(diabetes, hypertension, obesity, total cholesterol, current smoking, effort angina, clinical diagnosis, and degree of stenosis) assessed. Of 4 patients with ST segment elevation in treadmil exercise test, 1 patient with ST segment elevation in Ⅰ,Ⅲ,aVF had spasm in right coronary artery(100%) on coronary angiography, of 2 patients in V2-V4 had spasm in left anterior descending coronary artery in 1 patient(50%) and 1 patient in V5-V6 had spasm in left circumflex artery(100%). Positive treadmil exercise test was present in 11.2% of variant angina patient. If we have negative treadmil exercise result in patients with clinical manifestation of unstable angina at admission, we may have a suspicion of variant angina rather than multi-vessel disease. If we have exercise-induced ST segment elevation in patients with clinical manifestation of unstable angina at admission, we have a suspicion of variant angina rather than multi-vessel disease. Our result suggests that the correlation between the site of the ST segment elevation and the artery involved is quite good.

Baicalin 含有 제제의 生體利用率에 關한 硏究

엄정신,김영일,남용옥,양재헌 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

In order to increase bioavailabilities of Scutellariae Radix extract(SRE), very slightly soluble in oil phases and sparingly soluble in water phases, the preparation of emulsification was attempted. In previously studies in O/W and W/O forms emulsion, the stabilities were evaluated for each forms. In this study, the dissolution and bioavailabilies of each emulsion preparation of SRE were compared. The dissolution pattern of SRE in W/O emulsion was decreased more than O/W emulsion in dilute hydrochloric acid solution(pH1.2) and in phosphate buffer solution(pH 6.8). The absorption velocity of baicalin from W/P emulsion was slower than O/W emulsion. The absorption velocity of baicalin in stomach was slower than in duodenum and jejunum of rats. The time required for the maximum serum concentration (C_max) of baicalin from water phase, oil phase, O/W and W/O emulsion in mice were 30. 60, 90, and 120 minutes after oral administration respectively. The C_max of baicalin from water phase, oil phase, O.W and W/O emulsion in mice were 2.11, 0.61, 1.57, and 1.35 ug/ml respectively. The longer was the time required for C_max, the lower was C_max. If the bioavailability to water phase is 100, the relative bioavailability(RB) to W/O emulsion is 129.14 The result suggests that the improvement of bioavailability for baicalin in W/O emulsion might be practically available.

폐광지역 토양과 농작물 중의 중금속 오염도 조사

방은옥,정용준,조영채 忠南大學校 環境問題硏究所 2002 環境硏究 Vol.20 No.-

This study was conducted to investigate the concentration of the heavy metals among the soils and crops, and the difference compared with the unpolluted area from the radius distance from the ruined mine. Gubong Mind in Cheongyang-Gun, Chungnam-Do was selected as the ruined mine, which the Taechi-Myon district was selected ad the unpolluted control area. Pepper, welch onion, cabbage, radish and their soils were collected at the mine and unpolluted area, respectively. The concentration of heavy metals(Pb, Cd, Cu, Zn and As) were measured by ICP. In the soil sample, the average concentrations of all the heavy metals were significantly increased in the min area compared with those of the unpolluted area and significantly differed from the radius distance from ruined mine. In the crop sample, the average concentration of Pb, Zn and As metals were significantly increased in the mine area compared with those of the unpolluted area and all the heavy metals were significantly differed from the radius distance from ruined mine. There was a significant negative correlation among the soils from the radius distance from ruined mine and among the crops in the concentrations of all the heavy metals. There was a significant positive correlation between soils and crops in concentration of Pb, Cd, Zn and As metals. The results indicate the concentrations of heavy metals among the soils and crops at the ruined mine were saturated more than the unpolluted and the soil metals had spread to the crops. Consequently, we cannot leave the matter unsettled and its utilization must be studied to lower the contamination degree.