흰쥐에서의 카르복시메칠셀룰로오스나트륨과 겔란검 혼합겔의 유착방지 효과

권윤환,이시범,이정권,박용덕,박정숙,황성주 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.6

The aim of the present study was to investigate the efficacy of a mixed gel formulation composed of sodium carboxymethyl cellulose and gellan gum (Na-CMC gel) for the prevention of adhesions after laminectomv. The anti-adhesive effect of the Na-CMC gel was tested in a controlled randomized study using an animal model of lumbar laminectomv. The animals (60 female Sprague-Dawlev rats) were randomly allocated into two treatment groups to receive the Na-CMC gel on the injured area or no gel (control). The incidence of adhesions and their grade were blindly evaluated at 4. 8 and 12 weeks after surgery. The amount of scar tissue and tenacity were grossly reduced by the Na-CMC gel at postoperative 4. 8. and 12 weeks. The mean adhesion scores were 0.75. 125. and 1.38 at 4. 8. and 12 weeks in the gel-treated group. respectively. No significant inflammatory reaction was observed and the healing of wound was not affected by the Na-CMC gel. The Na-CMC gel reduced the amount of scar formation and tenacity in rat laminectomv model without affecting the healing of operation wound and other complications. Therefore. the Na-CMC gel may be the potential to prevent postsurgical adhesions in clinical state.

실비우스 수도를 경유한 뇌낭미충 낭종의 이주 -증례 보고-

김정훈,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

시가지내 산악경관의 시점 높이별 조망 특성 : 청주시 우암산을 대상으로 In a Case of Mt. Uam

정정섭,권상준,조태동 한국환경과학회 2004 한국환경과학회지 Vol.13 No.6

In this research, we have performed a T-test to see how the relationship between dependent variable or visual point level and independent variable or visual quantity is in order to clear up the correlation between pattern of visual point and visual quantity by the constituents of a view from a different visual point level and the results are as follows: 1) In case of the character of Mt.Uam landscape of the city, Uamsan is set as a fixed point and about a direction of view(D), the north is a datum point from which the range of direction is distributed within 180˚westwardly and the visual range(R) is also within 2000m. An elevation is an average of 7.4˚and the average story of the buildings is 3.85. Here the height of a story is about 4m so the average of the visual point difference is estimated at 15.4m. 2) The type of visual point is divided into the intersection group and the front of the highly used public buildings group. Double intersection types account for about 78.8%(52 spots) which forms a majority part of LCP. 3) The analysis of the difference of visual point level divided by eye level and that of the top of the buildings has been proved that there's a sharp difference resulted from t-test at 1% significant level. The significant difference of elevation from height difference(15.93m), however, has not been shown. 4) From the result of T-test about visual quantity by the elements of a view from a different visual point level, the visual quantity of mountain(VQM), sky(VQS). ground(VQG) is significant at about 1% each and that of building(VQB) is at about 5%. The difference in visual quantity of a mountain by the visual point level is at about 4% which can meet a marginal level of LCP necessary for evaluation of mountainscape.

砂耕栽培에 있어서 질소 및 칼리의 施肥水準의 오이의 生育, 收量 및 無機成分吸收에 미치는 影響

權成煥,鄭淳宰,具禹書,鄭景泰 東亞大學校 大學院 1993 大學院論文集 Vol.18 No.-

This experiment was conducted to study the effect of Nitrogen and Potassium treatment on growth, yield and content of mineral elements the results were summarized as follows; 1. Growth and Yields were more effective in N treatment with 8g per plant, were more effective in K treatment with 16 me per liter 2.Content of mineral elements in leaves were a lot of N and MG in N treatment, were a lot of P content in K treatment. 3. The content of mineral of Petiol, fruit and Xyleme sap. N and K were more contented in petiole, as the others were more contented in Xyleme sap. Ca was contented a little in fruit. 4. Absorption of water was increased in the N treatment with 8g per plants, in the K treatment with 16 me liter. The contents of chlorophyll was increased as the level of Nitrogen was increased in N treatment while, decreased on young leave in K treatment.

전사적 자원관리의 도입과 솔루션

권희철,유정상 경원전문대학 1999 論文集 Vol.21 No.-

So as to correspond with rapid business environment changes and obtain the competitiveness of company promptly, many companies are adopting ERP(Enterprise Resource Planning) system with best practice and IT(Information Technology) for the business process. ERP system is the integrated information system that controls resource of person and material efficiently to obtain the strong competitiveness of company. In this paper, we have surveyed the trend and the feature of ERP system recently, and proposed the point of the successful introduction and solution of ERP system. Lastly, we have analyzed the future market of ERP system.

노선 상업지역의 입체적 공간 이용에 관한 연구 : 청주시를 대상으로 in case of Chongju

권상준,정대영 淸州大學校 都市·地域開發硏究所 1996 都市·地域開發硏究 Vol.2 No.-

This study finds the characteristics of the three dimensional land use of linear commercial areas in case of Chongju as follows: a. The activities are connected with other commercial functions and facilities, involved high rised buildings. b. The tendency of upper floored buildings could represent the preference of commerce and business activities to the denser land uses and the higher the buildings. c. The structure of the land uses in linear commercial areas shows the effective allocation and centralization of commercial activities. This findings suggest as follows: a. To enlarge the spatial structure for dense and compact land use. b. To allocate appropriately urb in functions to enforcing the urban locational service. c. To establish political strategy to solve the land use systemizing for the management and effectiveness.

백서 Paraquat 두여에 의한 간과 폐 조직의 산화성 손상에서 Vitamin C와 Deferoxamine의 항산화 효과에 관한 연구

정연권,서길준,정중식,정성은,최국진,윤여규 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: The toxicity of paraquat has been known to be caused by oxygen free radicals which leads to the lipid peroxidation and multiple organ failure. Although vitamin C has been known to be a potent antioxidant, recently there are numerous data which have shown that a low dose of vitamin C may act as a prooxidant due to the stimulation of the Fenton reaction with metal ions, which produces hydroxyl radicals. It has been reported that a deferoxamine in paraquat intoxication could reduce the production of the hydroxyl radicals by the inhibition of the Fenton reaction through the reduction of iron ion in tissue. The aim of this study was to evaluate the effect of the high and low dose of vitamin C and deferoxamine on lipid peroxidation and plasma TNF-α in paraquat intoxication. Methods: Female Sprague -Dawley rats were divided into seven groups: control group which was not given paraquat(20 mg/kg), P group which was given paraquat only, PVH group given paraquat and high dose of vitamin C(100 mg/kg), PVL group given paraquat and low dose of vitamin C(10 mg/kg), PVHD given paraquat, high dose of vitamine C and deferoxamine(100 mg/kg), PVLD given paraquat, low dose of vitamin C and deferoxamine, and PD given paraquat and deferoxamine. Animals were killed at 6 and 24 hours after treatment. Malondialdehyde(MDA), superoxide dismutase(SOD) and glutathione(GSH) contents, catalase activity, plasma TNF-α, and histologic changes in the lung and liver tissue were measured. Results: The lung histology in the PVH and PD or PVHD groups showed the significant decreases in the alveolar edema and interstitial thickness compared to the P group. The liver histololgy in the PVH and PVHD groups demonstrated marked differences in the central venous and sinusoidal dilatation compared to that of the P group. While the MDA levels of the lung and liver in the PVH and PD groups showed the significant reduction compared to that of the P group at 6 hours after treatment, all groups showed the significant changes compared to the P group at 24 hours. There was no significant change of the SOD levels of the lung and liver at 6 hours among all groups. At 24 hours, the SOD levels of the lung in PVH, PVL, and PVHD groups showed the significant increases compared to the P group. The increase of the SOD level in groups combined with deferoxamine, however, revealed a little reduction. The SOD level of the liver in PVH group only significantly increased compared to the P group at 24 hours. There was no significant change of the GSH level of the lung and liver among all groups at 6 hours. At 24 hours, the GSH level of the lung and liver were significantly increased in both PVH and PD group and PVH group, respectively, compared to the P group. Although the catalase activity of the lung was not significantly increased, that of liver was signiflcantly increased in both PVHD and PD groups compared to the P group at 6 hours. The catalase activities of the lung and liver were significantly increased in PVH, PD, and PVHD at 24 hours. The concentrations of the plasma TNF-α were slightly decreased at 6 hours and slightly increased at 24 hours compared to that of the P group, but they were not significant. Conclusion: This study showed that although the low dose of vitamin C had no effect, the high dose of vitamin C revealed a decrease of the MDA level and an increase of SOD, GSH, and catalase activity in the lung and liver tissues, and the effect of the high dose of vitamin C increased with time. The administration of the deferoxamine with or without high dose of vitamin C, however, significantly showed the inhibition of the lipid peroxidation and antioxidant effect and low dose vitamin C decreased the effect of deferoxamine. The effects of the vitamin C and deferoxamine on plasma TNP-α were not clearly shown.

치근단절제 및 역충전와동 형성방법이 치근단누출에 미치는 영향

권태경,김성교,양정옥 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.2

디지탈방사선촬영술을 이용한 인접면 치아우식증 진단에 관한 실험적 연구

권기성,황의환,이상래 慶熙大學校 齒科大學 1994 慶熙齒大論文集 Vol.16 No.1

The purposes of this study were clinical comparison and evaluation between digital radiography and conventional radiography for the detection of artificial interproximal caries. Four freshly extracted, unrestored posterior teeth were obtained and canes was simulated by drilling semicircled defect with variable size at the interproximal surface of each tooth. The experiments were performed with IBM-PC/32 bit-DX compatible, video camera(VM-S8200, Hitachi Co., Japan), color monitor(Multisync 3D, NEC, Japan). Sylvia Image Capture Board for the ADC(analog to digital converter) was used, and spatial resolution was 512 x 480 with 256 gray levels. The obtained results were as follows: 1. At the condition of under exposure, the radiographs were superior to the digital images in readability. Also, as the size of the artificial lesion was increased, readability of the radiographs was elevated. 2. The digital images were superior to the radiographs in readability especially under over exsposure. 3. As the exposure time and size of lesion was increased, the gray level of region of interest of the digital image was decreased proportionally. 4. As the F-value of average gray level of region of interest at individual exposure time and size of lesion, gray level of the all lesion sizes was decreased in comparison with that of the normal enamel.

분화용 방향성 허브의 선호요인에 관한 연구

정정섭,권상준,조태동 韓國植物ㆍ人間ㆍ環境學會 2000 인간식물환경학회지 Vol.3 No.1

It is to present basic information on herb utilization in the future by understanding the preference factors of pot aromatic herbs through measuring analysis approach. To find out preference factors of pot aromatic herbs, we have selected 14 commonly favored herbs based on sales volume of major domestic pot-herb dealers through interviewing. At first we have studied the perceptive characteristics of herbs such as aroma, form, color and texture. And then, we have executed Duncan test by One-way ANOVA, factor analysis, meaningful difference verification between factors, and comparative analysis between averages. We have also studied on influence of correlation between the deference according to perceptive characteristics and the comprehensive preference. To understand the factorsin detail, we have executed Multiple Regression Analysis on correlations between the characteristics and the preference. Followings are the conclusions we have got from the study. 1. According to the results of Factor Analysis, there are three factors that can be perceived from the herbs. Those three factors can explain 61.70% of perceptive characteristics. It can be represented groups of factors such as Aromatic characteristics, Repose characteristics and Appreciation of beauty. Among them, from psychological factors, aroma related variable explains the best, beauty appreciation characteristics related variable the least. 2. According to the results of correlation analysis between comprehensive preference level and the specific preference level according to each perceptive characteristics, there are big differences between preference level by aroma and that by beauty and shows the highest correlation to the comprehensive preference of pot herbs. To see how much influence the beauty of herb makes on the comprehensive preference, we have executed the Regression Analysis. From the test, we knew that color was the most influential factor from the beauty characteristics. 3. To understand the factors shown in preference analysis in detail, we have executed the Multiple Regression Analysis on the correlation between perceptive characteristics and comprehensive preference. From the test, we concluded that pot aromatic herbs preference is decided by its fragrance, beauty of color and pleasant and happy smell it has.