유온감압법에 의한 슬러지의 탈수에 관한 연구

장성호,박진식,성낙창,김수생 동아대학교 환경문제연구소 1996 硏究報告 Vol.19 No.1

This study was to experiment, through sewage sludge treatment by Vacuum Frying Method, the effects of reaction condition come up to sludge water content. The results are as follows 1) On accassion the sewage sludge treatment by Vacuum Frying Method, the effect of pressure come up to water content, the water content decreased when the same reaction temperature and time was lower pressure more than the normal pressure(760㎜Hg), particularly. Since pressure 280㎜Hg increased water content decrease range. Since pressure(250㎜Hg) the water boiling point down sharply a phenomenon and the lower pressure lowered the water boiling point a phenomenon, the same sewage sludge water content evaporated rapidly the lower pressure more than the normal pressure. Accordingly, a close vacuum(40㎜Hg), showed very lower water content when a short reaction temperature and reaction time. 2) On accassion the sewage sludge treatment by vacuum Frying Method, the effect of reaction time come u to sludge water content, at the same reaction pressure and temperature, relatively the water content at a low reaction temperature(90℃, 120℃) decreased small in case of a long reaction time, the water content at a high reaction temperature(150℃, 180℃) decreased rapidly in case of a short reaction time. 3) On accassion the sewage sludge treatment by Vacuum Frying Method, the effect of come up to sludge water content, at the same reaction time and pressure, increase of reaction temperature decreased rapidly the water content.

쓰레기 매립장의 LFG 이용에 관한 기초연구

장성호,이덕생,김수생 동아대학교 환경문제연구소 1995 硏究報告 Vol.18 No.2

In this research, the optimum LFG pilot plant of extraction, purification, and application are selected by economic analysis, constructed and operated for the development of the standard LFG utilizing process process proper to domestic landfill. LFG recovery pilot plant was constructed at the base of the result of optimized design and economic evaluation performed at S,D landfill(landfil1 area : 514,345m², landfill depth : 23-39m, landfill MSW amount : 12,808,317m³, landfill period : 87.6-93.5) in Pusan. It was consisted of four extraction well(two extraction well with 18.5m depth, two extraction well with 10m depth), collection head with 160m length, scrubber with capacity 14m³/min as purification process, and flare stack as burning facilities. And monitoring well was set at 30, 50, 70, 90m far from extraction well for the estimation of influence radius. The following experiments were performed using the predeveloped LFG reconvery pilot plant. First, LFG generation amount and generation rate were estemated from the atom analysis of municipal solid waster in S,D landfill. Second, real LFG extraction rate of some 0-10㎥/min was obtanied from operating of LFG recovery process. Third, influence radius was estimated 85-100m according to varying 407㎥/min extraction rate. Fourth, composition of LFG was detected in extraction well and the before and after of purification process.

유온감압탈수처리한 슬러지의 재이용 가능성에 관한 연구

장성호,김수생 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.2

This study was to experiment, through sewage sludge treatment by Vacuum Frying Method, the sludge composition change before and after treatment, the thermal specific character, and the effects of treatment condition come up to sludge water content. The results are as follows. 1. The contents of crude protein and crude fat were respectively 4.8% and 3.4% before treatment, and those were 18.9% and 12.5% after theatment. 2. According to the results of Thermogravimetric analysis, the temperature ranges of themal decomposition were 290-430℃ and 250-380℃ before and after treatment. According to the results of Derivative Thermogravimetric analysis, the temperature of rapidly mass decreas occur respectively 320℃ and 280 C. For the more proper treatment and reuse of organic wastes, the continuous studies of Vacuum Frying Method are more needed.

SF-36에 의한 직장남성의 건강수준과 의료이용과의 관련성

김성아,박기수,장미경,감신 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4

Objectives: This study was performed to examine the health status measured by SF-36 and medical facilities utilization according to the health status measured by SF-36 in male workers. Methods: A self-administered questionnaire survey was administered to 786 male workers. Results: In bivariate analysis, physical functioning score was significantly different among the workers according to age, educational level, economic level, and job type. The bodily pain score and general health score were significantly different according to the workers' economic level and job type. The vitality score was significantly different according to the workers' age, educational level, economic level, and job type. The social functioning score was significantly different according to the workers' age, marital status, economic level, and job type. The role limitation emotion score was significantly different according to the workers' age, marital status, and job type. The mental health score was significantly different according to the workers' marital status, economic level, and job type (p<0.05). The SF-36 scores increased with higher workers' self-rated health status (p<0.05). The self-rated current health status of the workers was good when their economic status was high, their previous year health status was good and their SF-36 score was high (p<0.05). The rates of morbidity incidence and medical facilities utilization for 1 year were lower when workers' SF-36 score was high (p<0.05). Conclusions: In consideration of the above findings, SF-36 is suitable to measure health status and predict the medical utilization.

인체 요로상피암에서 angiogenin과 vascular endothelial growth factor의 mRNA발현

전성수,장훈,김원재 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: 혈관신생은 종양의 발생과 진행에 중요한 역할을 하며 angiogenin과 vascular endothelial growth factor (VEGF) 등과 같은 여러 인자가 관여한다. 본 연구에서는 방광내 요로상피암 조직에서 angiogenin과 VEGF mRNA 발현을 정량적으로 분석하여 이들 인자가 방광암에 미치는 영향을 조사하였다. 대상 및 방법: 방광암 조직 117예와 정상 방광 조직 17예를 대상으로 angiogenin과 VEGF mRNA 발현을 quantitative competitive polymerase chain reaction (QC-PCR) 방법으로 정량화 하였다. 방광암과 정상 방광 조직, 방광암과 동일 환자의 주변 정상 방광 조직, 종양의 분화도 및 병기에 따른 angiogenin과 VEGF mRNA 발현을 비교 분석하였다. 결과: 대조군의 정상 방광 조직이나 방광암 주변의 정상 방광 조직보다 방광암 조직에서 angiogernin과 VEGF 발현이 유의하게 증가하였다. 병기 Ta 방광암보다 병기 T1 또는 T2 이상의 방광암에서 anigiogenin 발현이 유의하게 증가하였다. 분화도 등급 I인 방광암 보다 등 급 III인 방광암에서 VEGF 발현이 유의하게 증가하였다. 그러나 방광암의 분화도에 바른 angiogernin 발현이나 방광암의 병기에 따른 VEGP 발현에는 유의한 차이가 없었다 결론: 혈관신생 인자인 angiogenin과 VEGF는 방광암의 증식에 관여하며, 특히 방광암 세포가 악성화됨에 따라 VEGF 발현이 증가하고 angiogenin에 의한 혈관신생은 종양의 병기가 Ta에서 T1 이상으로 진행하는데 중요한 역할을 할 것이다. Purpose: Tumor development and progression are angiogenesis-dependent, the Induction of which is mediated by several angiogenic factors including angiogenin and vascular endothelial growth factor (VEGF). This study was performed to evaluate the expression of angiogenin and VEGF in the tumor tissues of patients with urothelial carcinoma. The correlation of these factors with tumor grade and stage was also evaluated. Materials and Methods: The quantification for the expression of angiogenin and VEGF mRNA was assessed in 117 human bladder tumor tissues and 17 normal bladder mucosae using quantitative competitive polymerase chain reaction (QC-PCR). We compared the expression levels of angiogenin and VEGF mRNA between bladder tumor and normal bladder mucosae of controls, between bladder tumor and surrounding normal bladder mucosae, and according to tumor grades and tumor stages. Results: Angiogenin and VEGF mRNA expression in the bladder tumor tissue were significant1y higher than in the normal bladder mucosae of controls or surrounding normal bladder mucosae. Angiogenin expression in bladder tumor with stage T1 or above T2 was significantly higher than in bladder tumor with stage Ta. VEGF expression in bladder tumor with grade III was significantly higher than in bladder tumor with grade I. There was no significant difference in angiogenin expression with regard to the tumor grades and no significant difference in VEGF expression with regard to the tumor stages. Conclusion: These data suggest that angiogenesis mediated by angiogenin and VEGF may be involved in the neoplastic growth of urothelial carcinoma. As the grade of bladder tumor cells worsened, the VEGF expression increased. And, increased angiogenesis mediated by angiogenin seems to play a role in the progression of stage Ta bladder tumor to stage T1 or stage above T2.

모 제약회사 근로자들의 직업성 천식 유병률과 약제 분말 노출수준

오성수,최용휴,김은아,이영목,장재길,유장진,박승현,김태균,정수영,김규상,강성규 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 제약회사에서 직업상 천식의 유병 규모를 파악하고 작업공정에 대한 작업환경 측정을 통해 제약회사의 약제 분말에 대한 노출수준을 평가하고자 하였다. 방법: 제약회사에서 약제 분말에 노출되는 근로자를 대상으로 천식을 선별하기 위하여 설문조사 및 진찰, 혈액검사, 폐기능 검사 그리고 피부단자시험을 실시하였고, 각 부서별 공정에 따라서 총분진과 항생제 또는 효소제 분말에 대한 작업환경 측정을 실시하였다. 직업상 천식이 의심되는 근로자에 대하여 기관지과민성에 대한 검사(메타콜린을 이용한 비특이 기관지유발시험)와 약제 분말 기관지유발시험을 실시하여 확진하였다. 결과: 설문조사 및 진찰에서 작업 관련 천식 증상이 있는 근로자는 11명(34.4%)이었고, 약제 분말을 이용한 피부단자시험에서 1+ 이상 반응을 보인 근로자 10명(31.2%)이었다. 비특이 기관지유발시험 결과 8명(25.0%)이 양성(PC20 ≤16 mg/ml)이었다. 약제 분말 기관지유발시험을 통해 직업상 천식으로 확진된 근로자는 5명(15.6%)이었다. 작업환경 측정에서 원료를 충진하거나 투입하는 작업 그리고 정립작업에서 약제 분말에 대한 노출이 많았다. 결론: 제약회사에서 직업상 천식은 주로 제조공정 중 약제 분말에 노출된 근로자에서 발생하여, 증상 및 직업성 천식의 유병률이 높았다. 따라서 원료를 충진 또는 투입하는 작업과 정립작업 등 제조과적에서 약제 분말 노출을 줄이기 위한 세심한 주의가 필요하여, 약제 분말을 취급하는 근로자에 대해서는 천식 증상 조사뿐 아니라 정기적으로 피부단자시험, 비특이 기관지유발시험 등을 실시하여야 할 것이다. Objectives: After the investigation of one worker with occupational asthma, we surveyed the preva- lence of occupational asthma and the exposure level of pharmaceutical dust of 32 workers in a pharmaceutical company. Methods: Thirty-two of the 90 employees participated in the survey which consisted of questionnaire, blood sampling, spirometry and skin prick tests with 8 common allergens as well as 9 antibiotics and 2 enzymes. Various indices of the working environment were also measured. Subjects who had a symptom suggestive of work-related asthma or positive skin prick test were further investigated by PC20 methacholine. Nine subjects who had a PC20 result of 16 mg/ml or less (n=7) or had work-related symptoms and positive skin prick test (n=2) were referred to undergo a specific bronchial provocation test to phar- maceutical dust in an academic allergic disease center. Results: Eleven of 32 workers (34.4%) had a work-related symptom suggestive of occupational asthma. Ten (31.2%) showed positive skin prick test. 8 (25.0%) had a PC20 result of 16 mg/ml or less (indicative of significant bronchial hyperresponsiveness), and 5 (15.6%) had a positive result on the specific bronchial provocation test. Exposure levels of stuffing, input of raw materials and screening process were relatively high. Conclusions: This survey showed that pharmaceutical workers have an increased risk of occupational asthma. Although pharmaceutical factories maintain a relatively good working environment, careful control of respiratory tract exposures, especially during stuffing, input or raw materials and screening process, is important to prevent occupational asthma. Pharmaceutical workers need to undergo regular skin prick and methacholine bronchial provocation tests, as well as asthmatic symptom survey, to ensure the early detection and prevention of occupational asthma.

폐플라스틱수지와 제지슬럿지의 열분해에 관한 연구

설수덕,왕석주,장성호 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.2

The thermal decomposition of the sludge with Poly(acryloniti1e-butadiene-styrene) and Poly(styrene-co-acrylonitrile) were using a thermal analysis techniques in the stream of nitrogen gas of 30ml/min at various heating rates from 4 to 20℃/min. The mathematical, Derivative and Integral method were used to obtained values of activation energy of decomposition reaction. 1. The values of activation energy evaluated by Derivative and Intergral method were consistent with each other very well. 2. The maximum value of heat of decomposition evaluated by DSC method were 10, 120 cal/g at weight ratio of sludge/ABS=20/80 and 10, 500cal/g at weight ratio of sludge/SAN = 20/80. 3. The thermogravimetric trace curve agreed with the theoretical equation.

Staphylococcus lugdunensis에 의한 감염성 심내막염 1예

최성호,박현구,변승운,구동회,강호석,장항제,김양수,우준희,김영휘,최상호 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

Staphylococcus lugdunensis is a coagulase-negative staphylococcus (CNS) that is commonly found on the human perineal skin. Contrary to other CNS, S. lugdunensis is a rare contaminant in cultures and has the potential to cause clinically significant infections, including infective endocarditis. Infective endocarditis due to S. lugdunensis have been known to resemble endocarditis due to S. aureus because of its aggressive clinical course and high mortality. We report a case of infective endocarditis caused by S. lugdunensis in a 21-year-old woman. She was cured of the infection with surgical and antibiotic therapy. S. lugdunensis에 의한 감염성 심내막염은 국내에서보고가 없었던 매우 드물지만 다양한 합병증과 높은 사망률을 보이는 감염증이다. 저자들은 S. lugdunensis가 수술적 치료와 항생제 치료로 완치된 감염성 심내막염 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

일과성 전 기억상실증으로 나타난 크로이츠펠트 : 야콥병 1례

신대수,이승희,이한샘,박성욱,박현영,장혁,장성조,김요식,조광호 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.1

皮革廢水特性과 處理에 관한 硏究

김수생,손희정,장성호,김철,박현건 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.1

1. In biological treatment with AB-Process At A-step : as treatment condition operated HRT about 4hr and F/M ration below 5㎏BOD/㎏MLSS·d obtained removal efficiency of COD, BOD are respectively 30-40%, 15-25%. At B-step : as treatment condition operated HRT about 30hr and F/M ratio below 0.2㎏ BOD/㎏ MLSS·d obtained removal efficiency of COD. BOD are respectively 75-82%, above 91%. On the other hand, statistical overview of correlationship both unstable nondegradable pollutant removal efficiency in B-step and treatment of A-step, it found that excessive removal of BOD in-A-step bring about low loading in B-step caused a bad influence in stabilizing treatment. 2. The defect of AB-process are wanting actual domestic and difficult of A-step management but resistent in loading change, high loading and nonbiodegradable wastewater. And total capacity and electric cost could be reduced respectively about 50%, 40%, when these were campared wit conventional activated sludge system.