http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
HPLC를 이용한 고추의 품종별 Capsaicin 및 Dihydrocapsaicin 성분의 함량 분석
맹주양;이용구;이숙재;정진아;나성희;김창원;심혜진 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2
Five kinds of Korean red pepper-pinkish, perfect, cucumber, blue, and ground cherry-were used, respectively, to analyze the contents of Capsaicin and Dihydrocapsaicin. The comparative analysis was performed separately in the seed removed red pepper and the seed included red pepper by HPLC. Among the seed removed pepper, the results for the content of Capsaicin were shown as follows: ground cherry(2204.0ppm) > pinkish(1324.9ppm) > blue(906.7ppm) > cucumber (77.2ppm) > perfect(12.9ppm), and the results for the content of Dihydrocapsaicin were shown as follows: ground cherry (1004.8ppm) > pinkish(248.3ppm) > blue(165.7ppm) > cucumber(13.9ppm) > perfect(0.0ppm). Among the seed included red pepper, the results for the content of Capsaicin were shown as follows: ground cherry(2190.lppm) > pinkish(1324.4ppm) > blue (919.9ppm) > cucumber(79.5ppm) > perfect(11.7ppm), and the results for the content of Dihydrocapsaicin were shown as follows: ground cherry(1017.4ppm) > pinkish(270.6ppm) > blue(189.0ppm) > cucumber(39.4ppm) > perfect(0.0ppm). Overall results suggest that in the contents of Capsaicin and Dihydrocapsaicin, the seed removed pepper and the seed included red pepper both were decreased in the order of ground cherry > pinkish > blue > cucumber > perfect, and this order is proportional to the strength of hot taste of red pepper.
60 Hz 자기장이 예쁜꼬마선충의 생식에 미치는 영향 연구
박병재,장혜진,김희성,강희은,심례림,최유미,김윤명,김남,김윤원,Park, Byeong-Jae,Jang, Hye-Jin,Kim, Hui-Seong,Gang, Hui-Eun,Sim, Rye-Rim,Choe, Yu-Mi,Kim, Yun-Myeong,Kim, Nam,Kim, Yun-Won 한국전자파학회 2010 전자파기술 Vol.21 No.5
60 Hz 자기장에서 예쁜꼬마선충(C. elegans)의 발생 및 생식에 미치는 영향을 조사하였다. 자기장 노출 조건은 $0{\sim}500\;{\mu}T$이며, 실험 온도는 선충의 일반적 배양 온도 범위($2 1.2{\pm}0.6^{\circ}C$)에서 일정하게 유지하였으며, 노출은 선충의 배양 기간 동안 지속되었다. C. elegas 야생형 N2 및 스트레스에 민감한 hsf-1와 crt-1 등의 돌연변이체들에서 실험에 사용한 노출 조건에 따른 생식력의 차이는 없었다. 여러 세대에 걸쳐 자기장에 노출한 경우에도 자기장에 의한 생식력의 변화는 없었다. 결론적으로, C. elegans는 크기가 매우 작으므로(길이 약 1 mm) 유도전류가 적게 발생하여, 자기장($-500\;{\mu}T$)에 의한 영향이 없는 것으로 사려된다.
박혜연(Hye Yeon Park),원동란(Dong Ran Won),김혜원(Hye Won Kim),송승하(Seung Ha Song),심현섭(Hyun Sub Sim) 한국언어치료학회 2016 한국언어치료학회 학술발표대회 논문집 Vol.2016 No.12
Purpose: Autism spectrum disorder (ASD) is a developmental disorder with primary deficits in the areas of social interaction and repetitive behaviors. Although there has been increased identification of disfluencies in individuals with autism, however, little is known about their characteristics of disfluencies in school aged children. The purpose of this study was to investigate disfluency characteristics in school-age children with high functioning autism spectrum disorders(HF-ASD) and children who stutter (CWS). Methods: The participants were 8 school-age children with ASD and 8 CWS. All participants were ranged in ages from 6 and 8 years and they matched for age and severity of stuttering (mild to moderate). Reading, story retelling and picture description task were administered to collect speech samples. Disfluencies in the speech samples were identified and classified as either other disfluencies(OD) or stuttering-like disfluencies (SLD). Results: Results showed that two groups did not differ in distribution of disfluency types(%). In reading task, there was a significant difference between two groups in whole-word repetition, and in storytelling task significant differences were observed in both par-word repetitions and blocks. However, there was no significant difference in disfluency types in picture description task. Conclusions: These results suggested that children with HF-ASD showed comparable fluency types compared to CWS. However, atypical disfluencies such as word final disfluencies(WFD) was identified in HF-ASD. While as linguistic demands increased in storytelling task children with HF-ASD produced more interjections and revisions, CWS showed more part-word repetitions.
Bl6 Melanoma세포에서 Citrus Essential Oil이 Melanin 생성에 미치는 영향
임혜원(Hye Won Lim),조남영(Nam Young Cho),윤미연(Mi Yun Yoon),차상복(Sang Bok Cha),김경원(Kyoung Won Kim),박영미(Young Mi Park),이지윤(Ji Yun Lee),이진희(Jin Hee Lee),김창종(Chang Jong Kim),심상수(Sang Soo Sim) 대한약학회 2003 약학회지 Vol.47 No.1
This study is performed to investigate the effects of citrus essential oils on melanin production in Bl6 melanoma cells. Five kinds of citrus essential oils (Bergamot, Grapefruit, Lemon, Mandarin, Petigrain) did not have any influence on DPPH radical scavenger activity cell growth and cytotoxicity in Bl6 melanoma cells. Both mandarin and petigrain essential oils dose-dependently inhibited purified tyrosinase activity, but bergamot did not. In 1μM MSH-stimulated Bl6 melanoma cells, all of 5 citrus essential oils inhibited melanin production in a dose dependent manner. From the above results, it is possible that citrus essential oils may be development to be an anti-melanogenesis agent on the basis of their inhibitory effect on MSH-induced melanin production.
강혜심 ( Hye Sim Kang ),임은선 ( Eun Seon Im ),최승아 ( Seung Ah Choi ),전혜원 ( Hye Won Jun ),이택상 ( Taek Sang Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.2
Benign metastasizing leiomyoma (BML) is a rare entity, defined as a muscle tumor in association with one or more smooth muscle tumor of the uterus and without evidence of any extra uterine primary site. The lung is the most common site of involvement,2 and the etiology of BML remains unknown. We experienced a case of BML arising in pelvic and para-aortic lymph nodes and report with a brief review of literature.
Hye-Ock Jang,Dong-Won Kim,Byeong-Ill Kim,Hong-Gu Sim,Young-Ho Lee,Jong-Hwa Lee,Jung-Ha Bae,Moon-Kyoung Bae,Tae-Hyuk Kwon,Il Yun 대한생리학회-대한약리학회 2004 The Korean Journal of Physiology & Pharmacology Vol.8 No.2
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine effects of chlorhexidine digluconate on differential rotational mobility, while changing the probes substitution position (n) in the membrane phospholipids aliphatic chain. Magnitude of the rotational mobility of the intact six membrane components differed depending on the substitution position in the descending order of 16-(9-anthroyloxy)palmitic acid (16-AP), 12, 9, 6, 3 and 2-(9-anthroyloxy)stearic acid (12-AS, 9-AS, 6-AS, 3-AS and 2-AS). Chlorhexidine digluconate increased in a dose-dependent manner the rate of rotational mobility of hydrocarbon interior of the OPGTL prepared with total lipids extracted from cultured OPG, but decreased the mobility of membrane interface of the OPGTL. Disordering or ordering effects of chlorhexidine digluconate on membrane lipids may be responsible for some, but not all of its bacteriostatic and bactericidal actions.
Hye-Won Park,Eun-Sim Kim,Eun-Joo Na,Mi-Hae Yun 대한예방치과학회 2017 International Journal of Clinical Preventive Denti Vol.13 No.3
Objective: Effective removal of the dental plaque in the gingival sulcus and proper massage of the gingiva have been the important things to control the early stage of gingivitis, through the development of newly designed tooth-brush use. Methods: Three groups of materials were classified as experimental group for sulcus tooth-brush, positive control group as using the modified sulcus tooth-brush, and the control group as the plane tooth-brush as Buttler No. 209. Partial dentition model was produced as frontal and posterior portion by use of the extracted teeth on Molar teeth and upper anterior teeth on the dental plaster covered with the latex typed and open and close typed artificial gingiva. 10 times back and forth movement tooth-brushing was performed to all groups of the dental models, painted with the artificial plaque and plaque dying on the tooth surface and in the gingival sulcus, by use of the automatic tooth-brushing machine. The residual amounts of the artificial plaque was calculated and estimate the relative amounts of the removal of the artificial plaque in the dental plaque on each group, and compared them each others. Results: The clearance area of the artificial plaque in the gingival sulcus area was more in experimental group or positive control group than that of the control group at all portions of the tooth both in anterior and posterior teeth. Conclusion: Sulcus cleansing U-shaped tooth-brush was recommended to use for the Bass technique tooth-brushing in order to cleansing the dental plaque.
Endothelin-1에 의한 Phospholipase C-Ca^2+이동 신호전달계에 미치는 TMB-8과 W-7의 방향
심상수,이정근,문성원,김현준,이윤혜,박진형,김창종 중앙대학교 약학연구소 1999 약학 논총 Vol.13 No.-
Phospholipase C activity and intracellular Ca^2+ concentration were measured to investigate effects of TMB-8 and calmodulin antagonist on signal pathway of phospholipase C-Ca^2+ mobilization induced by endothelin-1. Activation of phospholipase C and increase in intracellular Ca^2+ concentration by endothelin-1 were dependent on extracellular Ca^2+ concentration. Both TMB-8, a intracellular Ca^2+ release blocker, and W-7, a calmodulin antagonist, significantly increased phospholipase C activity induced by endothelin-1, whereas did not elevate the intradcellular Ca^2+ concentration. This result suggests that both TMB-8 and W-7 have dual effects on signal pathway of phospholipase C-Ca^2+ mobilization induced by endothelin-1.
Determinants of Nicotine Dependence in Chronic Obstructive Pulmonary Disease
Sim, Yun Su,Lee, Jin Hwa,Kim, Ki Uk,Ra, Seung Won,Park, Hye Yun,Lee, Chang-Hoon,Kim, Deog Kyeom,Shin, Kyeong-Cheol,Lee, Sang Haak,Hwang, Hun Gyu,Ahn, Joong Hyun,Park, Yong Bum,Kim, Yu-Il,Yoo, Kwang Ha The Korean Academy of Tuberculosis and Respiratory 2017 Tuberculosis and Respiratory Diseases Vol.80 No.3
Background: Smoking cessation is the most powerful intervention to modify progress of chronic obstructive pulmonary disease (COPD), and nicotine dependence is one of the most important determinants of success or failure in smoking cessation. We evaluated nicotine dependence status and investigated factors associated with moderate to high nicotine dependence in patients with COPD. Methods: We included 53 current smokers with COPD in the Korean Obstructive Lung Disease II cohort enrolled between January 2014 and March 2016. Nicotine dependence was measured by using Fagerstrom test for nicotine dependence (FTND). Cognitive function was assessed by Korean version of Montreal Cognitive Assessment. Results: The median FTND score was 3, and 32 patients (60%) had moderate to high nicotine dependence. The median smoking amount was 44 pack-years, which was not related to nicotine dependence. Multiple logistic regression analysis revealed that high education status (odds ratio, 1.286; 95% confidence interval, 1.036-1.596; p=0.023), age <70 (odds ratio, 6.407; 95% confidence interval, 1.376-29.830; p=0.018), and mild to moderate airflow obstruction (odds ratio, 6.969; 95% confidence interval, 1.388-34.998; p=0.018) were related to moderate to high nicotine dependence. Conclusion: Nicotine dependence does not correlate with smoking amount, but with education level, age, and severity of airflow obstruction. Physicians should provide different strategies of smoking cessation intervention for current smokers with COPD according to their education levels, age, and severity of airflow obstruction.