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      • 배달 미니 게임 개발:"최고의 웨이터를 꿈꾸며"

        김정훈,정한교,김영옥,김중곤,박정윤,윤진성,김경식 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

        본 미니 게임은 웨이터라는 직업을 모티브로 하여서 남녀노소 누구나 재미를 느낌과 동시에 기억력 향상시켜 주는 게임제작이라는 목적아래 제작되었다.본 논문에서는 이 게임의 제작과정을 기술하고자 한다.이 게임은 제3회 AGC(한국 아마추어 게임제작 공모전)에서 우수 작으로 선정되었다.

      • X-관련성 만성육아종성질환의 진단을 위한 PMA-activated NBT 검사

        김중곤,조한익,오흥범,김의종,최강원 대한감염학회 1996 감염 Vol.28 No.1

        목적 : Activated NBT 검사는 만성육아종성질환을 선별하는 검사이다. 활성제로 PMA를 사용하면 X-linked CGD의 경우 보인자를 감별할 수 있다. 방법 : CGD의 가족력을 부인하는 정상인 30명을 대상으로 PMA activated NBT 슬라이드 검사를 실시하여, 정상대조에서의 formazan 형성율을 보았으며, 동일 검사를 CGD가 강력히 의심되는 환자와 그 가족에 대하여 실시하였다. 결과 : 정상대조 30명 전원에서 98% 이상의 formazan 형성세포가 관찰되었다. 환자에게 실시한 결과 세환자 모두에서 0%의 결과를 보였다. 환자의 어머니에서는 각각 57, 70, 67%의 결과를 보였다. 결론 : 본 연구를 통하여 세 환자는 X-관련성 만성육아종성질환이라는 진단을 내릴 수 있었다. PMA activated NBT 슬라이드 검사는 시행하기가 쉽고 재현성이 좋으므로, 어러 검사실에서 소아기 면역결핍증을 선별하는 검사의 하나로 시행되는게 바람직하다고 사료된다. Background : Chronic granulomatous disease(CGD) is uncommon inherited disorder in which phagocytic cells fail to produce antimicrobial superoxide(O₂) due to NADPH oxidase deficiency. This disease can be easily screened by activated nitroblue tetrazolium(NBT) test. In case of X-linked CGD, carriers also can be detected. Methods : PMA(phorbol myristate acetate) activated NBT test was performed as previously described. Test performance was evaluated in 30 normal persons who denied family history mimicking CGD. Test was also applied to the three strongly suspected cases of CGD. Two of the cases were 12 year old boy and 7 year old boy, who suffered from many infectious diseases since 6 month old and 4 month old, respectively. The other remaining case was 22 year old man who suffered from many infectious diseases since 6 year old, but now relatively in health compared to the other two cases. Results : More than 98% formazan formation was observed in all normal controls. No formazan positive cell was shown in all of the three patients. However, applied to the mothers, the test revealed 57%, 70%, 67% positive cells, respectively. Conclusion:X-linked transmission of CGD could be determined with the results of PMA activated NBT slide test. This test can be easily performed. It would be better to do this test routinely as one of the tests for the screening of the immmunodeficiency syndrome in childhood.

      • SCOPUSKCI등재

        백서 창상의 피복방법에 따르는 Muofibroblast의 생성 및 소실되는 과정의 실험적인 비교관찰

        김한중,최희윤,조철현,이인승 大韓成形外科學會 1985 Archives of Plastic Surgery Vol.12 No.1

        The question of how skin coverage affects contracting wounds has long been a significant problem in the study of wound contraction. Myofibroblasts appear to be well established as the cellular cause of wound contraction. Myofibroblasts are found in many types of contracting wounds, including granulating wounds and hypertrophic burn scars. Myofibroblasts in contracting wounds have definitive life cycles, being present when contraction is active and then disappearing when contraction has ceased. In this study, we observated comparatively quantitative changes in the surface area by planimetry and changes of myofibroblasts by electron microscope through 8 weeks according to the types of skin coverage. The purpose of this study was to evaluate the myofibroblast population in skin coveraged wounds in a rat model, which allowed frequent biopsies as well as precise identificaion of the interface of the skin coverage and the wound bed. The results of our experiments are as follows: 1. Granulating wound Contracted rapidly and had long persistence of myofibroblasts. 2. Split-thickness skin graft Contrated less and myofibroblasts were more rapidly decreased and were disappeared at 5 weeks later. 3. Full-thickness skin graft Minimum contracti aondnmyofibroblasts were very rapidly decreased and were disappeared at 4 weeks later. 4. Local flap No contraction and could not find myofibroblast. Slowly increase in size at begining. 5. Contraction was influenced by number and lasting time of myofibroblast.

      • 농업구조물의 안전진단 및 개·보수 공법 선정 시스템 개발

        김종옥,고만기,최진용,김기동,윤광식,김한중 公州大學校 産業開發硏究所 1998 産業開發硏究 Vol.6 No.-

        A study was conducted to develope a system for safety appraisal and repair works on agricultural structures. Location, size, type, maintenance record, structural and functional problems of agricultural structures in Yedang irrigation district were surveyed. A grahpic user interface program assisting onsite field investigation of typical agricultural structural problems such as fractures and cracks of members was developed. Typical rehabilitation methods were investigated and coded for database development.

      • 난소암조직 Acid Deoxyribonuclease의 분리와 성상에 관한 연구

        김두상,김영신,고재경,한중수 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1

        In order to find out a possible role of acid deoxyribonuclease (DNase) in carcinogenesis of the ovary, activity of the enzyme was measured and the nature of the enzyme was studied in serous cystadenocarcinoma and endodermal sinus tumor of the ovary following the purification of the acid DNase in the tumor tissue of the ovary. (1)The acid DNase activity was greatly increased in the tumor tissues of the ovary, serous cystadenocarcinoma and endodermal sinus tumor tissues, while neutral and alkaline DNase activities were unchanged in the tumor tissues. This may indicate that the acid DNase can be used as a biochemical marker for the ovary tumors. (2)Proteins in the tumor tissues of the ovary were separated by a DEAE-cellulose column chromatography into 7 peak, respectively, of which one peak protein each appeared to be specific for serous cystadenocarcinoma and endodermal sinus tumor. (3)Acid DNases in the tumor tissues of the ovary were isolated into a single peak, respectively. The size of peak in the tumor tissues was greater than that in the control tissue of the ovary, indicating that the acid DNases in the tumor tissues were activated, but not specific for the tumors. (4)Acid DNases in the tumor tissues of the ovary were partially purified by centrifugation and a DEAE-cellulose column chromatography. The purified enzyme was highly active against double stranded DNA (ds-DNA), even though some activity was found against single stranded DNA (ss DNA). Observations that acid DNase from serous cystadenocarcinoma tissue was highly active and specific to ds DNA compared with ss DNA suggested that the enzyme might play a role in transforming normal ovarian cells into cancer cells.

      • 진공차단기용 영구자석형 엑추에이터 최적설계

        김한균,김중경,이정근,한성진 東亞大學校附設 情報技術硏究所 2005 情報技術硏究所論文誌 Vol.13 No.1

        The vacuum interrupter operated by permanent magnet actuator(PMA) gives outlook on improved characteristic, higher reliability and cost price reduction as well as the feature of simple structure and few component. For the anlysis and design of permanent magnetic actuator, not only electric, magnetic and mechanical phenomena but also material properties should be taken into account. Aim of the present paper is modeling of permanent magnet actuator(PMA) used in medium voltage distribution systems and remodeling by permanent magnetic. Coupled finite element method is used to analysis the modeling and we compared with previous PMA model and improved PMA model.

      • DC Parameter Test System 개발

        金俊植,愼漢重 호서대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.19 No.-

        in this Paper, we developed the DC parameter system which inspects the property of DC parameter for semiconductor products. The conventional system has complex hardware. Also the interfacing with IBM-PC is hard because that was almost materialized by analogy circuits. The proposed system is interfaced by IBM-PC. It is consisted of CPLD (Complex Programmable Logic Device) part, ADC (Analogue to Digital Converter), DAC (Digital to Analogue Converter), voltage/current source, variable resistor and measurement part. In the proposed system, we have designed the constant voltage source and the constant current source in a part. The CPLD part is designed by VHDL (VHSIC Hardware Description Language), which it generates the control and converts the serial data to parallel data. Voltage source part generates analogue test voltage and maintains that one. Current source part generates the analogue test current and maintains the current. ADC part converts analogue data to 16 bits digital data. DAC part converts the 12 bits digital test voltage to analogue voltage. Variable resistor is the part far the controlling the range of current. The proposed DC parameter test system has two test channels and it operates VFCS (Voltage Force Current Sensing) mode and CFVS (Current Force Voltage Sensing) mode. The normal resistor with error range ±5% and diode is tested. When the normal resistor testing about 10% error is measured. When the diode testing about 7% error is measured.

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