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      • 2002년 부산아시아게임과 부산체육의 백년대계

        하형주,이동갑 東亞大學校 附設 스포츠科學硏究所 1995 스포츠科學硏究論文集 Vol.13 No.-

        To construct main-stadium and physical education-related facilities at kang-seo area is considered essential result when we ultimately watch the problem which land of scale, proportion development of city, geographic or financial condition, safety and security, and guarantee of cultural place to give next generation. We sure that Pusan Asian Games for the unity, cooperation, peace promotion of 3 billion Asian successfully will be held. and 2002 Asian Games, simply, is not at once physical education event but occupy the basic facility of city and excellent strategic dimension which prepare decisive opportunity of 21st century Pusan prosperity also, We must not to neglect comprehensive public opinion. 2002 Asian Games for the successful hold, epoch-making opportunity of Pusan Properity, cultural level promotion of Pusan citizen, will be construct main stadium, dormitory for the athletes, press center, broadcasting center, and so forth and Pusan Asian Games will be achieve globalization.

      • KCI등재

        평가 문항을 통한 중학교 과학영재 학생들의 빛 개념 지식상태 분석

        이형재,하지선,박상태 韓國英才學會 2011 영재교육연구 Vol.21 No.4

        이 연구에서는 K대학교 영재교육원의 중학교 과학영재 학생들 30명을 대상으로 빛에 관한진단평가 15문항을 개발하여 적용하였다. 그리고 빛에 대한 학생들의 지식상태에 관하여 지식공간론을 활용하여 분석하고 이것으로부터 얻은 위계를 도식화함으로써 중학교 과학영재학생들의 지식상태를 파악함은 물론 교수 학습 방법을 개선하기 위한 기초자료로 활용하고자하였다. 이러한 연구 목적을 달성하기 위하여 중학교 과학영재 학생들의 빛에 대한 지식상태평가결과를 분석하였고, 문항 간 위계구조 및 개별 학생들의 지식상태를 분석하였다. 그 결과학습 집단 내에서 개인별로 서로 다른 지식구조를 갖고 있었고, 이에 따른 학습 진단도 서로다르게 평가해야 함을 알 수 있었으며, 평가 문항과 문항 간의 관계(위계 구조)와 개별 학습자의 지식상태를 알 수 있게 한다는 시사점을 얻을 수 있었다. In this study, we developed and applied 15 evaluation questions about light to 30middle school students in K University Science Education Institute for the Gifted .Then we used the theory of knowledge space and analyzed the middle school ScienceGifted Students' knowledge state about light. By schematizing the hierarchy from it, weintended to not only measure students' knowledge state about light, but use it as thebasic materials to improve teaching methods. To achieve the purpose of this study, weanalyzed the evaluation results and individual knowledge state and hierarchy ofquestions. As a result, there were different knowledge structures in the individual, andwe found that we should diagnose them differently. In addition, we have hadimplications that it has the connection with each questions and the individualknowledge state.

      • 경사진 트레드밀에서 후방보행운동을 통한 넙다리네갈래근 강화와 요통의 관계

        박주완,김경,김형욱,김재우,배솔희,서정표,이정구,정하영 대구대학교 특수교육재활과학연구소 2010 再活科學硏究 Vol.28 No.1

        목적: 본 연구에서는 경사진 트레드밀에서의 후방 보행 훈련을 통한 넙다리네갈래근의 강화가 요통 환자의 치료에 미치는 영향을 알아보고자 하였다. 대상: 만성 요통을 호소하는 16명의 환자를 대상으로 연구를 실시 하였다. 방법: 트레드밀을 10° 경사로 맞춰놓은 상태에서 대상자들은 하루 20분, 일주일에 3회의 빈도로 2주 동안 훈련을 하였다. 표면 근전도를 가지고 넓다리 곧은근, 안쪽 넓은근, 가쪽 넓은근, 척추 세움근의 %MVIC를 측정하였고, KODI와 VAS를 통해 대상자들의 통증정도를 측정하였다. 결과: 넓다리 곧은근은 훈련전에 비해 훈련을 하고 난 후 상대적으로 높은 근전도를 보였고, 통계적으로 유의하였다(p<.05). 안쪽 넓은근과 가쪽 넓은근 또한 높은 근전도율을 보였지만 통계적으로 유의하지는 않았다. 척추 세움근은 훈련전에 비해 훈련을 하고 난 후 높은 근전도율을 보여주었고, 통계적으로 유의하였다(p<.05). VAS와 KODI의 평균값은 명백하게 감소되었고, 통계적으로 유의하였다(p<.05). 결론: 이상의 결론을 종합하면, 후방보행을 통한 넙다리네갈래근의 강화는 요통의 감소에 효과적이라고 사료되며, 더불어 넙다리네갈래근으로 접근하여 요통을 경감하는 중재방법이 효과적인 치료 방법이 될 수 있다는 것을 의미한다. Purpose: This study was to investigate the influence of strengthening the Quadriceps femoris through backward walking treadmill training in the patients who have lower back pain. Subjects: Sixteen subjects with chronic lower back pain were included. Method: In the training, the treadmill was set to have a inclination of 10 degrees, and the subjects were trained for 20 minutes a day, 3 times a week, for 2 weeks. %MVIC(muscle power) of rectus femoris, vastus medialis oblique, vastus lateralis and erctor spinae were measured with surface EMG, and KODI and VAS were used to measure the subject's level of pain. Results: Quadriceps femoris showed relatively higher average electromyogram rates than that before training(p<.05). Vastus medialis oblique and vastus lateralis also showed higher average electromyogram rates, but no significant change in them was noted. Erector spinae showed higher average electromyogram rates than that before training(p<.05). The average points of VAS and KODI clearly decreased(p<.05). Conclusion: Strengthening Quadriceps femoris seems to be efficient for relieving lower back pain in this study.

      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

      • SCOPUSKCI등재

        Clinical Characteristics of Smoking Asthmatics

        Ha, Eun Sil,Kim, Hye Ok,Lee, Kyoung Ju,Lee, Eun Joo,Hur, Gyu Young,Jung, Ki Hwan,Lee, Sung Yong,Kim, Je Hyeong,Lee, Sang Yeub,Shin, Chol,Shim, Jae Jeong,Kang, Kyung Ho,Yoo, Se Hwa,In, Kwang Ho The Korean Academy of Tuberculosis and Respiratory 2009 Tuberculosis and Respiratory Diseases Vol.67 No.6

        Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second ($FEV_1$) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean $FEV_1$ (% predicted) was 76.8${\pm}$19.8%, 71.6${\pm}$21.1% and 87.9${\pm}$18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The $FEV_1$/forced vital capacity (FVC) (ratio, %) values were 63.6${\pm}$12.6%, 59.3${\pm}$14.9% and 72.1${\pm}$11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual $FEV_1$ slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients.

      • SCIESCOPUS
      • SCISCIESCOPUS

        Process development of oxalic acid production in submerged culture of Aspergillus niger F22 and its biocontrol efficacy against the root-knot nematode Meloidogyne incognita

        Lee, Sang Il,Lee, Keon Jin,Chun, Ho Hyun,Ha, Sanghyun,Gwak, Hyun Jung,Kim, Ho Myeong,Lee, Jong-Hee,Choi, Hak-Jong,Kim, Hyeong Hwan,Shin, Teak Soo,Park, Hae Woong,Kim, Jin-Cheol Springer-Verlag 2018 BIOPROCESS AND BIOSYSTEMS ENGINEERING Vol.41 No.3

        <P>Oxalic acid has potent nematicidal activity against the root-knot nematode Meloidogyne incognita. In this study, fermentation parameters for oxalic acid production in submerged culture of Aspergillus niger F22 at 23, 25, and 30 A degrees C were optimized in 5-L jar fermenters. The viscosity of the culture broth increased with increasing temperature. There was a negative correlation between oxalic acid production and the apparent viscosity; high volumetric productivity of oxalic acid was obtained at low apparent viscosity (less than 1000 cP), with a productivity of more than 100 mg/L h. When the apparent viscosity was over 2500 cP, the volumetric productivity decreased below 50 mg/L h. In addition, the volumetric mass transfer coefficient, K (L) a, positively correlated with volumetric productivity. When the K (L) a value increased from 0.0 to 0.017 /s, the volumetric productivity proportionally increased up to 176 mg/L h. When the temperature decreased, K (L) a increased due to the decrease in viscosity, leading to increased volumetric productivity. The highest productivity of 7453.3 mg/L was obtained at the lowest temperature, i.e., 23 A degrees C. The nematicidal activity of culture filtrate was proportional to the content of oxalic acid. Based on a constant impeller tip speed, oxalic acid production was successfully scaled up to a 500-L pilot vessel, producing a final concentration comparable to that in the 5-L jar.</P>

      • GG-19 : Treatment outcome with methotrexate for the interstitial pregnancy

        ( Hyeong In Ha ),( Hyeon Ha Seok ),( Mi Ra Kim ),( Mi Kyeong Kim ),( Seok Ju Sung ),( Woo Sik Lee ),( Tae Ki Yoon ),( Yong Wook Jung ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

        목적: The purpose of this study is to evaluate the treatment outcome with methotrexate (MTX) for the interstitial pregnancy with respect to the success rate of MTX treatment and the result of subsequent pregnancy. 방법: This study is a retrospective study that performed in an urban university based hospital from Jan 2005 to July 2014. Total 101 cases of interstitial pregnancy were diagnosed and treated surgically or medically in the department of obstetrics and gynecology, CHA Gangnam Medical Center. Of those 38 cases were initially treated with MTX conservatively. The authors collected patient demographics, treatment regimen, number of doses administered, treatment results, and subsequent pregnancy outcomes by reviewing patients` medical records. 결과: Initially 7 patients were treated with combination of systemic MTX and direct MTX injection into gestational sac under the guidance of transvaginal sonography. 29 patients were treated with systemic MTX only. Of those, 6 (85.7 %) patients and 17 (58.6%) patients were successfully treated with combination MTX and systemic MTX, respectively. 12 patients tried to be pregnant. 10 (83.3%) patient were pregnant. There were several complication related to pregnancy including a case of uterine rupture from treatment failure , 3 cases of preterm deliveries. The median age of patients were 32 (range, 24-40). The b-hCG level at the diagnosis was 79312 (range, 374.8 - 159000). Fetal heart beat was noted in 5 cases (13.1%). A subject who tried to be pregnant experienced heterotopic pregnancy including tubal pregnancy. 결론: Methotrexate treatment for interstitial pregnancy may be an alternative for surgical approach. However, further study will be required to determine the factors that affect treatment results.

      • Cytotoxic and apoptosis-inducing activities against human lung cancer cell lines of cassaine diterpenoids from the bark of <i>Erythrophleum fordii</i>

        Ha, Manh Tuan,Tran, Manh Hung,Phuong, Thien Thuong,Kim, Jeong Ah,Woo, Mi Hee,Choi, Jae Sue,Lee, Suhyun,Lee, Jeong Hyung,Lee, Hyeong Kyu,Min, Byung Sun Elsevier 2017 Bioorganic & medicinal chemistry letters Vol.27 No.13

        <P><B>Abstract</B></P> <P>A phytochemical investigation into the bark of <I>Erythrophleum fordii</I> yielded four new compounds, two new cassaine diterpenoids (erythrofordin T and U, <B>1</B> and <B>2</B>) and two new cassaine diterpenoid amines (erythroformine A and B, <B>6</B> and <B>7</B>), as well as nine known compounds. We report for the first time the isolation of erythrofordin V (<B>3</B>) from a natural source and that of the remaining eight known diterpenoids (<B>4</B>–<B>5</B>, <B>8</B>–<B>13</B>) from <I>E. fordii</I>. All structures were elucidated using spectroscopic analysis. Cytotoxic activity of the isolated compounds (<B>1</B>–<B>13</B>) was examined <I>in vitro</I> against three non-small cell lung cancer cell lines (A549, NCI-H1975, and NCI-H1229) using the MTT assay. Cassaine diterpene amines (<B>6</B>–<B>10</B>, <B>12</B>, <B>13</B>) exhibited potent cytotoxic activity against all three cell lines with IC<SUB>50</SUB> values between 0.4μM and 5.9μM. Erythroformine B (<B>7</B>) significantly induced apoptosis in all three cancer cells in a concentration-dependent manner.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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