http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김정일,김병권,김정원,채창호,이철호,강동묵,김지홍,김진하,김영욱,이영하,이지호,김정호,윤형렬,유철인,정백근,장태원,김운규,윤동영,강진욱,김종은,안진홍,이동준,장준호,이광영,송혜란,최영희,이용환,조병만,최홍렬,고상백,김은아,이유진,홍영습,정갑열,김정만,김준연 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1
Objective: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases Methods: l l hospital participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted. Results: Between April 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. most of the HAVS cases came from shipbuilding, and 172 of them (92.7%) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9%). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6%) and 4 (12.1%) cases of occupational asthma, the agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10(58.8%) of the cases were diagnosed as squamous cell carcinoma and 5(29.4%) as adenoma. Conclusion: This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.
Cheol Song, Geun,Sim, Hee-Jung,Kim, Sang-Gyu,Ryu, Choong-Min Oxford University Press 2016 Annals of botany Vol.118 No.4
<P>Background and Aims Plants modulate defence signalling networks in response to various biotic stresses via inter-organ communications. The root-mediated transmission of systemic acquired resistance (SAR) against soilborne and air-borne plant pathogens from SAR-induced plants to neighbouring plants subjected to local chemical and pathogen treatments was evaluated. Methods The first two plants out of ten Nicotiana benthamiana seedlings were pre-treated with the SAR-triggering chemical benzothiadiazole (BTH). All ten seedlings were then challenged with two pathogenic bacteria, i.e. the root (bacterial wilt) pathogen Ralstonia solanacearum and the leaf (wildfire) pathogen Pseudomonas syringae pv. tabaci, at 7 d after SAR induction. Key Results Disease severity was noticeably lower in BTH-pre-treated plants than in the control. Surprisingly, two plants located next to BTH-treated plants exhibited reduced disease symptoms indicating that SAR signal transmission occurred through the root system. Determinant(s) secreted from the root system were search for and it was found that salicylic acid (SA) is a major molecule involved in SAR transmission through the root. Analysis of the expression of the defence-related genes N. benthamiana pathogenesis-related gene 1a (NbPR1a) and NbPR2 confirmed that BTH treatment elicited SAR via root-root transmission between plants. Plants with knock-down of the multiple resistance component SGT1 and SA biosynthesis-related gene ICS1 by Tobacco rattle virus-mediated virus-induced gene silencing exhibited a lack of root-mediated SAR transmission. The biological relevance of this finding was validated by challenge with the SAR-inducing avirulent pathogen P. syringae pv. syringae instead of BTH, which produced similar results. Conclusions Our findings demonstrated that SAR is transmissible through the root system from SAR-triggered plants to neighbouring plants.</P>
Song, Geun Cheol,Choi, Hye Kyung,Ryu, Choong-Min Oxford University Press 2013 Annals of botany Vol.111 No.5
<P><B>Background and Aims</B></P><P>The use of vitamins including vitamin B<SUB>1</SUB>, B<SUB>2</SUB> and K<SUB>3</SUB> for the induction of systemic acquired resistance (SAR) to protect crops against plant pathogens has been evaluated previously. The use of vitamins is beneficial because it is cost effective and safe for the environment. The use of folate precursors, including <I>ortho</I>-aminobenzoic acid, to induce SAR against a soft-rot pathogen in tobacco has been reported previously.</P><P><B>Methods</B></P><P>In the present study, <I>para</I>-aminobenzoic acid (PABA, also referred to as vitamin B<SUB>x</SUB>) was selected owing to its effect on the induction of SAR against <I>Xanthomonas axonopodis</I> pv. <I>vesicatoria</I> in pepper plants through greenhouse screening.</P><P><B>Key Results</B></P><P>Dipping of pepper seedlings in a 1 m<SMALL>m</SMALL> PABA solution in field trials induced SAR against artificially infiltrated <I>X. axonopodis</I> pv. <I>vesicatoria</I> and naturally occurring cucumber mosaic virus. Expression of the <I>Capsicum annuum pathogenesis-related 4</I> gene was primed in response to pathogen infection as assessed by quantitative real-time PCR. The accumulation of cucumber mosaic virus RNA was reduced in PABA-treated pepper plants at 40 and 105 d post-treatment. Unexpectedly, fruit yield was increased in PABA-treated plants, indicating that PABA-mediated SAR successfully protected pepper plants from infection by bacterial and viral pathogens without significant fitness allocation costs.</P><P><B>Conclusions</B></P><P>The present study is the first to demonstrate the effective elicitation of SAR by a folate precursor under field conditions.</P>
Song, Geun Cheol,Ryu, Choong-Min Korean Society for Molecular and Cellular Biology 2018 Molecules and cells Vol.41 No.8
Plant defence responses to various biotic stresses via systemic acquired resistance (SAR) are induced by avirulent pathogens and chemical compounds, including certain plant hormones in volatile form, such as methyl salicylate and methyl jasmonate. SAR refers to the observation that, when a local part of a plant is exposed to elicitors, the entire plant exhibits a resistance response. In the natural environment, plants are continuously exposed to avirulent pathogens that induce SAR and volatile emissions affecting neighbouring plants as well as the plant itself. However, the underlying mechanism has not been intensively studied. In this study, we evaluated whether plants "memorise" the previous activation of plant immunity when exposed repeatedly to plant defensive volatiles such as methyl salicylate and methyl jasmonate. We hypothesised that stronger SAR responses would occur in plants treated with repeated applications of the volatile plant defence compound MeSA than in those exposed to a single or no treatment. Nicotiana benthamiana seedlings subjected to repeated applications of MeSA exhibited greater protection against Pseudomonas syringae pv. tabaci and Pectobacterium carotovorum subsp. carotovorum than the control. The increase in SAR capacity in response to repeated MeSA treatment was confirmed by analysing the defence priming of the expression of N. benthamiana Pathogenesis-Related 1a (NbPR1a) and NbPR2 by quantitative reverse-transcription PCR compared with the control. We propose the concept of plant memory of plant defence volatiles and suggest that SAR is strengthened by the repeated perception of volatile compounds in plants.
Song, Geun Cheol,Im, Hyunjoo,Jung, Jihye,Lee, Soohyun,Jung, Man‐,Young,Rhee, Sung‐,Keun,Ryu, Choong‐,Min BLACKWELL SCIENCE 2019 ENVIRONMENTAL MICROBIOLOGY Vol.21 No.3
<P><B>Summary</B></P><P>Archaea have inhabited the earth for a long period of time and are ubiquitously distributed in diverse environments. However, few studies have focused on the interactions of archaea with other organisms, including eukaryotes such as plants, since it is difficult to cultivate sufficient numbers of archaeal cells for analysis. In this study, we investigated the interaction between soil archaea and <I>Arabidopsis thaliana</I>. We demonstrate for the first time that soil archaea promote plant growth and trigger induced systemic resistance (ISR) against the necrotrophic bacterium <I>Pectobacterium carotovorum</I> subsp. <I>carotovorum</I> SCC1 and biotrophic bacterium <I>Pseudomonas syringae</I> pv. <I>tomato</I> DC3000. Ammonia‐oxidizing archaeon <I>Nitrosocosmicus oleophilus</I> MY3 cells clearly colonized the root surface of <I>Arabidopsis</I> plants, and increased resistance against both pathogenic species via the salicylic acid‐independent signalling pathway. This mechanism of bacterial resistance resembles that underlying soil bacteria‐ and fungi‐mediated ISR signalling. Additionally, volatile emissions from <I>N. oleophilus</I> MY3 were identified as major archaeal determinants that elicit ISR. Our results lay a foundation for archaea–plant interactions as a new field of research.</P>
Song, Geun Cheol,Ryu, Choong-Min Molecular Diversity Preservation International (MD 2013 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.14 No.5
<P>Systemic acquired resistance (SAR) is a plant self-defense mechanism against a broad-range of pathogens and insect pests. Among chemical SAR triggers, plant and bacterial volatiles are promising candidates for use in pest management, as these volatiles are highly effective, inexpensive, and can be employed at relatively low concentrations compared with agrochemicals. However, such volatiles have some drawbacks, including the high evaporation rate of these compounds after application in the open field, their negative effects on plant growth, and their inconsistent levels of effectiveness. Here, we demonstrate the effectiveness of volatile organic compound (VOC)-mediated induced resistance against both the bacterial angular leaf spot pathogen, <I>Pseudononas syringae</I> pv. lachrymans, and the sucking insect aphid, <I>Myzus persicae</I>, in the open field. Using the VOCs 3-pentanol and 2-butanone where fruit yields increased gave unexpectedly, a significant increase in the number of ladybird beetles, <I>Coccinella septempunctata</I>, a natural enemy of aphids. The defense-related gene <I>CsLOX</I> was induced by VOC treatment, indicating that triggering the oxylipin pathway in response to the emission of green leaf volatiles can recruit the natural enemy of aphids. These results demonstrate that VOCs may help prevent plant disease and insect damage by eliciting induced resistance, even in open fields.</P>
Is obesity associated with gastropharyngeal reflux disease?
Choi, Cheol Woong,Kim, Gwang Ha,Song, Chul Soo,Wang, Soo Geun,Lee, Byung Joo,I, Hoseok,Kang, Dae Hwan,Song, Geun Am WJG Press 2008 World journal of gastroenterology Vol.14 No.2
<P>To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD).</P>
Inhibitory effects of polyphenols isolated from Rhus verniciflua on Aldo-keto reductase family 1 B10
( Dae Geun Song ),( Joo Young Lee ),( Eun Ha Lee ),( Sang Hoon Jung ),( Chu Won Nho ),( Kwang Hyun Cha ),( Song Yi Koo ),( Cheol Ho Pan ) 한국생화학분자생물학회 (구 한국생화학회) 2010 BMB Reports Vol.43 No.4
Aldo-keto reductase family 1 B10 (AKR1B10) is a member of the NADPH-dependent aldo-keto reductase (AKR) superfamily, and has been considered to be a potential cancer therapeutic target. Total extract from the bark of Rhus verniciflua (Toxico-dendron vernicifluum (Stokes)) showed AKR1B10 inhibitory activity. To identify the active compounds from R. verniciflua responsible for AKR1B10 inhibition, nine compounds were isolated via bioactivity-guided isolation and tested for their effects against recombinant human AKR1B10 (rhAKR1B10). Results showed that butein, isolated from the ethyl acetate fraction, was most able to inhibit rhAKR1B10. The inhibitory rate of butein against rhAKR1B10 was 42.86% at 1 μM with an IC50 value of 1.47 μM, and enzyme kinetic analysis revealed its inhibition mode to be uncompetitive. [BMB reports 2010; 43(4): 268-272]