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Roxythromycin-tylosin-furaltadone 합제의 닭 유래 세균에 대한 시험관내 항균효과
김지영,채미경,윤효인,서상희,박배근,김현수,전무형 충남대학교 수의과대학 동물의과학연구소 2003 動物醫科學硏究誌 Vol.11 No.-
In vitro antimicrobial susceptibility of roxythromycin (Rx), tylosin (Tyl), erythromycin (EM) and furaltadone (Fur) was studied, either by the single type or the combinated type of Rx-Tyl-Fur (RTF) against E. co1i (30 strains), Staph. aureus (20 strains) and Mycoplasma gallisepticum (5 strains) that are the major pathogens in poultry farm. The paper disk diffusion and MIC tests were applied. In screening test by paper disk diffusion method, the single types of antibiotics showed the sensitivity against 55 strains of bacteria in order of Fur, EM, Rx and Tyl. The combinated RTF showed the higher rate of sensitivity (80∼83.3% at 64㎍/disk, 60-75% at 32㎍/disk) and wider range of growth inhibiting zone (19.6±3.7-24.8±4.7mm) than those of the single drugs. In MIC test, the sensitivity against the 55 strains appeared in order of Fur. EM, Rx and Tyl as similar to those of paper disk diffusion method. The MIC ranges of RTF were 0.125∼16㎍/ml for E. coli, 0.25∼16㎍/ml for Staph. aureus and 1-8㎍/ml for Myco. gallisepticum, showing evidently lower than those of the single types. The MIC_(50) and MIC_(90) of RTF were estimated l∼4㎍/ml and 8∼16㎍/ml, respectively, and remarkably lower than those of the single drugs.
Bae, Chae Yun,Min, Mun-kyeong,Kim, Hail,Park, Je-Kyun Royal Society of Chemistry 2014 Lab on a chip Vol.14 No.13
<P>A microstructure-based hydrogel was employed to study the relationship between spatial specificity and cellular behavior, including cell fate, proliferation, morphology, and insulin secretion in pancreatic β-cells. To effectively form homogeneous cell clusters in vitro, we made cell-containing hydrogel membrane constructs with an adapted grid structure based on a hexagonal micropattern. Homogeneous cell clusters (average diameter: 83.6 14.2 μm) of pancreatic insulinoma (MIN6) cells were spontaneously generated in the floating hydrogel membrane constructs, including a hexagonal grid structure (size of cavity: 100 μm, interval between cavities: 30 μm). Interestingly, 3D clustering of MIN6 cells mimicking the structure of pancreatic islets was coalesced into a merged aggregate attaching to each hexagonal cavity of the hydrogel grid structure. The fate and insulin secretion of homogeneous cell clusters in the hydrogel grid structure were also assessed. The results of these designable hydrogel-cell membrane constructs suggest that facultative in vitro β-cell proliferation and maintenance can be applied to biofunctional assessments.</P>
Mechanical stimulation of bovine embryos in a microfluidic culture platform
Chae Yun Bae,김민석,박제균 한국바이오칩학회 2011 BioChip Journal Vol.5 No.2
We demonstrate a membrane-based microfluidic in vitro cultivation system that regulates the pattern of mechanical stimulation using a micro-modulated syringe pump. Using independent control of flow and compressive force, we applied an in vivo-like mechanical stimulus to bovine embryos in a microfluidic channel. To compare the accuracy of the compressive strain, we observed any morphological change in the embryos using a lateral view of the microfluidic device. Moreover, the compressive strain via mechanical stimuli with different duration times was analyzed. Based on the mechanical behavior of the stimulated embryos, we found that both the amplitude of the pressure and the duration of the stimulus were significant factors. The device is expected to be useful for the development of new methods to precisely control the mechanical stimulation of embryonic growth by mimicking peristaltic constriction in vivo.
채지영 ( Chae Ji Yeong ),윤수인 ( Yun Su In ),배상석 ( Bae Sang Seog ),채희복 ( Chae Hui Bog ),박선미 ( Park Seon Mi ),윤세진 ( Yun Se Jin ),박진우 ( Park Jin U ),배일헌 ( Bae Il Heon ),김석형 ( Kim Seog Hyeong ),송형근 ( Song Hye 대한소화기학회 2004 대한소화기학회지 Vol.43 No.2
Jejunal infarction as a complication of acute pancreatitis is not common and can not be well recognized. This jejunal infarction usually arises from the venous thrombosis rather than arterial thrombosis. Jejunal infarction results in bowel perforation or stenosis according to its extension of injury and progression rate. Pathologic findings of the involved jejunum show a segmental transmural infarction and mesenteric venous thrombotic occlusions. Early diagnosis should be made for better prognosis. We report a patient with jejunal infarction resulting perforation due to acute pancreatitis, in which the initial presenting symptoms were hematemesis and abdominal distention. (Korean J Gastroenterol 2004; 43:120-124)
여대생의 내현적 자기애가 폭식행동에 미치는 영향 : - 외모에 대한 사회문화적 태도의 매개효과 -
배금채(Geum-Chae Bae),윤채영(Chae-Young Yun) 신라대학교 여성문제연구소 2020 젠더와 사회 Vol.31 No.-
본 연구에서는 여대생의 내현적 자기애가 폭식행동에 미치는 영향을 살펴보고, 이 과정에서 외모에 대한 사회문화적 태도가 매개변인의 역할을 하는지 검증하였다. 이를 위해 부산에 소재하는 5개 대학교에 재학 중인 여대생을 대상으로 설문을 실시하여, 총 356부를 분석에 사용하였다. 측정도구로는 폭식행동 척도(BULIT-R), 내현적 자기애 척도(CNS), 외모에 대한 사회문화적 태도 척도(SATAQ)를 사용하였다. 본 연구의 목적을 달성하기 위해 SPSS 22.0과 AMOS 22.0을 사용하여 기술통계분석과 Pearson 상관분석, 측정모형의 확인적 요인, 구조모형 분석, 부트스트 래핑으로 분석하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 여대생의 폭식행동과 내현적 자기애, 외모에 대한 사회문화적 태도의 관계에서 모든 변인 간에 통계적으로 유의미한 정적 상관이 나타났다. 둘째, 여대생의 내현적 자기애가 폭식행동에 미치는 영향에서 외모에 대한 사회문화적 태도가 부분 매개하는 것으로 나타났다. 본 연구는 여대생의 내현적 자기애가 폭식행동에 미치는 영향에서 외모에 대한 사회문화적 태도가 매개변인의 역할을 한다는 것을 밝힘으로써 내현적 자기애자의 심리적 특성을 이해하고 상담자의 치료적 개입과 프로그램 개발에 있어서 시사점을 제공하였고, 제한점과 후속 연구의 필요성을 제안하였다. The purpose of this study was to examine the effects of covert narcissism on binge eating behavior of female university students and to examine whether sociocultural attitudes towards appearance, which was an environmental variable, play a role in mediating variables. For this purpose, questionnaire research was administered to female university students attending five universities in Busan, and a total of 356 copies were used for the analysis. The Bulimia Test Revised(BULIT-R), the Covert Narcissistic Scale(CNS), and the Sociocultural Attitudes towards Appearance Questionnaire(SATAQ) were used as the measurement tools. To achieve the purpose of this study, statistical analysis was performed using reliability analysis, mean, standard deviation, Pearson correlation analysis, structural equation modeling analysis, and bootstrapping using SPSS 22.0. and AMOS 22.0. The results of this study were summarized as follows. First, there was statistically significant correlation between all the variables in the relationship between binge eating behavior, covert narcissism and sociocultural attitudes towards appearance of female university students. Second, the effect of covert narcissism on binge eating behavior in female university students was found to be partial mediated by sociocultural attitudes towards appearance. This study demonstrated the role of sociocultural attitude toward appearance as a mediating variable in the impact of covert narcissism on binge eating behavior in female college students, thus understanding psychological characteristics of covert narcissist and providing implications for therapeutic intervention and program development by counselors. The implications of the study were discussed based on this study result, and the limitation and the necessity of follow-up study were suggested.