증례 : 순환기: 신장암 환자에서 Pazopanib을 사용한 후 발생한 심부전 1예

이송이 ( Song I Lee ),임병훈 ( Byung Hun Lim ),김영준 ( Young Jun Kim ),강상우 ( Sang Woo Kang ),박철 ( Chull Park ),송주흥 ( Joo Heung Song ),안선호 ( Seon Ho Ahn ) 대한내과학회 2016 대한내과학회지 Vol.90 No.4

신장암 환자에서 VEGFR-TKIs과 관련된 심부전은 드무나 생명을 위협할 수 있는 위험한 부작용으로 pazopanib으로 인한 심각한 심부전은 거의 없는 것으로 알려져 있다. 국내에서 pazopanib으로 인한 심각한 심부전에 대하여서는 보고된 바가 없다. 이에 저자들은 pazopanib 투여한 이후 발생한 심각한 심부전 1예를 경험하였으며 pazopanib 투여시 주기적인 심장기능 평가 필요성 및 증상 발현 시에 약물 중단을 통하여 증상 호전을 기대할 수 있어 이에 대하여 증례보고한다. A 78-year-old man was diagnosed with renal cell carcinoma, and left nephrectomy was performed. He started pazopanib. One month later, he visited our hospital because of general weakness and dyspnea. His oxygen saturation was low. A chest X-ray showed pulmonary edema and bilateral pleural effusion. An echocardiogram showed a larger left ventricle and lower ejection fraction than observed at the previous examination. The patient discontinued pazopanib and started diuretics and digoxin. His symptoms improved and a follow-up X-ray showed improvement in the pulmonary edema with bilateral pleural effusion. (Korean J Med 2016;90:330-333)

코스메슈티컬 화장품의 소비가치와 만족도 -피부질환 고민을 중심으로-

이송이 ( Song-i Lee ),김민정 ( Min-jeong Kim ),박정아 ( Jeong-a Park ) 한국미용학회 2022 한국미용학회지 Vol.28 No.5

In the modern times, people have been concerning more about their skin diseases resulting from environmental pollution and climate changes. At the same time, the cosmeceutical market whose roles have become segmented and specialized has expanded its reach. This study aimed to investigate the consumption values and consumer satisfaction of cosmeceuticals depending on skin diseases. It is meaningful in that it suggests basic data which are needed for manufacturers to set a direction for production and develop marketing strategies. According to this study, respondents believe that ‘functional value’ is most important among consumption values. As ‘functional value’ increased, consumer satisfaction improved accordingly. Satisfaction with cosmeceuticals was high in all groups because most cosmeceuticals are now of high quality and perceived as the products which are effective in easing diverse skin diseases with soothing, moisturizing and whitening effects. Therefore, it is required for manufacturers to develop more diverse and new technologies and enhance product quality and performances. More diverse studies are required to facilitate the steadily growing cosmeceutical market.

사회참여에 관한 의과대학생의 인식 조사와 의학교육의 방향

이송이,장동호,박소연,윤태영,권오영,Lee, Song I,Chang, Dong-ho,Park, So Youn,Yoon, Tai Young,Kwon, Oh Young 연세대학교 의과대학 2018 의학교육논단 Vol.20 No.2

In the ever-changing medical environment, the social participation of medical doctors is becoming more necessary. Currently, there is not enough participation or action by doctors within our society due to reasons such as a lack of educational curriculum in this area. This study aimed to investigate medical students' opinions and attitudes about social participation and action. A total of 438 medical students were surveyed about their attitudes toward doctors' relations with the public, social participation, social action, and medical education for social participation or action. Regarding doctors' relations with the public, participants responded that the government (73.5%) and the media (82.0%) were causing social distrust of doctors, and more than 70% of the respondents answered that doctors were passive when it comes to social participation. When asked about social participation and social action, 76.7% of the students surveyed had experienced social participation, and 28.3% had experienced taking social action. A total of 73.4% of the students answered that medical education needs to be changed, and it is necessary to introduce subjects such as sociology and law to improve social participation and action. The results are significant in that they show medical students' thoughts on social participation and social action as doctors in the Fourth Industrial Revolution. We believe that a change of medical curriculum to promote active and collaborative social participation by doctors is necessary.

관용어 의미 유형과 친숙도에 따른 학령기 고기능 자폐스펙트럼장애 아동의 관용어 이해 능력

이송이(Song I Lee),배희숙(Hee Sook Bae),이영미(Young mee Lee) 한국언어청각임상학회 2016 Communication Sciences and Disorders Vol.21 No.2

배경 및 목적: 본 연구에서는 관용어 유형(감정표현, 행위표현)과 친숙도(고, 저)에 따른 학령기 고기능 자폐스펙트럼장애 아동과 일반 아동 간의 관용어 이해 정확도에 유의한 차이가 있는지 살펴보고, 집단 내에서 오류 유형에 따른 오답률에 유의한 차이가 있는지 살펴보고자 하였다. 방법: 동작성 지능과 언어발달이 정상 범위에 있는 학령기 고기능 자폐스펙트럼장애 아동(N=15)과 생활연령을 일치시킨 일반 아동(N=15)을 대상으로 하였다. 관용어 유형과 친숙도를 고려하여 개발한 관용어 이해 과제를 대상 아동에게 실시하여, 관용어 유형과 친숙도에 따른 이해 정확도를 측정하고 오류 유형에 따른 오답률을 산출하였다. 결과: 고기능 자폐스펙트럼장애 아동의 관용어 이해 정확도는 일반 아동에 비해서 유의하게 낮았으며, 고기능 자폐스펙트럼장애 아동은 행위표현에 비해서 감정표현에서 관용어 이해 정확도가 유의하게 낮았다. 두 집단 모두 친숙도가 높은 관용어의 이해 정확도가 친숙도가 낮은 관용어보다 유의하게 높았다. 오답 유형 분석 결과, 고기능 자폐스펙트럼장애 아동은 오답 유형 간에 유의한 차이가 없었다. 논의 및 결론: 고기능 자폐스펙트럼장애 아동의 관용어 이해 능력은 일반 아동에 비해서 낮았으며, 감정표현 관용어와 친숙도가 낮은 관용어의 이해 능력이 일반 아동에 비해 취약한 것으로 나타났다. 이는 고기능 자폐스펙트럼장애 아동의 관용어 이해 능력 향상을 위해서 관용어 유형과 친숙도를 고려한 중재가 필요함을 시사한다. Objectives: The purposes of this study were to investigate the differences in comprehen-sion between children with high-functioning autism spectrum disorder (HFA) and children with typical development (TD) by type of idiom (emotion/action expression) and familiar-ity (high/low) and to investigate the proportion of misunderstood idioms (literal interpre-tation, idiom quote) within each group. Methods: Fifteen children with HFA and 15 age-matched children with TD were included in this study. An idiom comprehension task was developed for the study, which consisted of 40 items (10 emotion-familiar idioms, 10 emo-tion-unfamiliar idioms, 10 action-familiar idioms, and 10 action-unfamiliar idioms). Results: The idiom comprehension accuracy of children with HFA was significantly lower than chil-dren with TD. Children with HFA showed significantly lower accuracy than children with TD in comprehending emotion idioms. Both children with HFA and children with TD had sig-nificantly higher accuracy in familiar idioms than in unfamiliar idioms. For children with HFA, there was no significant difference in the proportion of misunderstanding between literal interpretation of idioms and idiom quote. Conclusion: Children with HFA showed lower accuracy in idiom comprehension than children with TD. Children with HFA had more difficulties in comprehending emotion idioms and unfamiliar idioms than children with TD. These results suggest that the type and familiarity of idioms should be considered in teaching idioms to children with HFA in speech-language therapy.

DEA모형을 이용한 상수관망 위험관 선정 방법에 관한 연구

이은환(Lee, Eun Hwan),이송이(Lee, Song I),김아린(Gim, A Rin),전환돈(Jun, Hwan don) 대한토목학회 2022 대한토목학회 학술대회 Vol.2022 No.10

흑미 무논점파 재배방법에 따른 수량 및 품질특성과 잡초방제체계

조승현,이덕렬,이송이,이기권,Cho, Seung-Hyun,Lee, Deok-Ryeol,Lee, Song-I,Lee, Ki-Kwon 한국잡초학회 한국잔디학회 2017 Weed & Turfgrass Science Vol.6 No.3

흑미를 이용한 무논점파 재배방법에 따른 입모, 수량, 품질특성 등을 구명하고 효과적인 잡초방제체계를 결정하여 재배안정화를 유도함으로써 흑미를 이용한 무논점파 재배의 보급 확대를 위한 기초자료를 제공하고자 수행하여 얻어진 결과는 다음과 같다. 흑미 무논점파 재배에서의 효과적인 잡초방제체계는 제초효과가 높고 약해에도 안전하였던 bromobutide thiobencarb (파종 전 5일) followed by bensulfuron mefenacet thiobencarb (파종 후 12일) 체계처리가 유리할 것으로 판단되었다. 파종시기 및 재식밀도에 따른 흑미의 입모수는 파종시기가 늦어지고 재식밀도가 높아질수록 증가하였으며 출수기는 파종시기가 늦어질수록 지연되었으나 재식밀도별로는 차이가 나타나지 않았다. 흑미의 가장 중요한 품질요소인 안토시안함량은 파종시기가 늦어지고 재식밀도가 낮아질수록 높아지는 경향이었으며 완전 착색 현미수량은 5월 30일과 6월 10일 파종 $3.3m^2$당 80주에서 이앙재배 대비 99% 수준으로 가장 높게 나타났다. 이상의 결과들을 종합해 보면 흑미를 이용하여 무논점파 재배를 할 경우 적정 재식밀도는 $3.3m^2$당 80주였고 중만생종 품종으로 사료맥류 후작인 6월 10일 파종까지는 수량감소가 거의 없어 안전하게 재배가 가능하며 식용맥류 후작인 6월 20일 파종에서는 중만생종 품종은 지양하고 조생종 품종을 선택하여야만 비교적 안전하게 재배가 가능할 것으로 판단되었다. This study was conducted to investigate the change of yield and quality according to seeding time and planting density and to determine effective weed control method in wet-hill-seeding use black colored rice. The most effective weed control system was application of bromobutide thiobencarb five days before seeding followed by bensulfuron mefenacet thiobencarb 12 days after seeding (barnyardgrass at 2.5-3.0 leaf stage). The seedling stand by seeding time and planting density increased with the delay seeding time and high planting density. The heading dates were delayed as the seeding time became late but no difference was found between planting density. The anthocyanin content of black colored rice was higher at late seeding time and lower planting density. The yield of full colored rice was high 80 plants per $3.3m^2$ in seeding on May 30 and June 10. This information could be useful for spreading rice direct seeding by inducing stabilization of wet-hill-seeding use black colored rice.

엘러스-단로스 증후군에 발생한 자발성 신장동맥 박리

임병훈 ( Byung-hun Lim ),이송이 ( Song-i Lee ),임재홍 ( Jae-hong Lim ),오수진 ( Su-jin Oh ),주민수 ( Min-su Chu ),안선호 ( Seon-ho Ahn ),변승재 ( Seung-jae Byun ) 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.1

Primary dissection of the renal artery is rare. Spontaneous renal artery dissection can be associated with diseases such as medial degeneration, neurofibromatosis, syphilitic arteritis, tuberculosis, polyarteritis nodosa, Marfan syndrome, fibromuscular dysplasia, or Ehlers-Danlos syndrome (EDS). Among these causes, EDS related renal artery dissection is very rare worldwide and has not been previously reported in Korea. EDS are a group of heritable connective tissue disorders characterized by fragility of the skin and hypermobility of the joints. We describe the case history of a young man who presented with left side flank pain, hypermobility of the hand joints and showed left renal artery dissection on computed tomography and angiography that turned out to be the first complication of vascular type EDS.

화력발전소 바닥재를 이용한 간척지토양의 물리성 개선효과

박현정 ( Park Hyun Jung ),이선일 ( Lee Sun Il ),이송이 ( Lee Song I ),이동석 ( Lee Dong Suck ),최우정 ( Choi Woo Jung ) 한국농공학회 2008 한국농공학회 학술대회초록집 Vol.2008 No.-

Crop growth in the reclaimed tideland soils is likely to be inhibited by poor soil physical conditions such as poor aeration and drainage, and high salinity primarily due to high contents of fine particles. Bottom ash which is by-products of power plant using coals can used as soil conditioner of the tideland soils because particle of bottom ash is coarse and their mineral compositions are very similar to soils. In this study, the effect of bottom ash application to tideland soils on improvement of soil conditions and subsequent crop production was investigated in a 50-days of green house experiment. Lettuce (Lactuca sativa) was selected as the target crop as it is known to be very sensitive to salinity stress. Bottom ash was mixed with soil collected from a reclaimed tideland at Goheung, Chonnam province at different rates (0, 5, 10, 20, 30, 40, 50, 75 w/w %). Application of bottom ash substantially decreased EC of the mixture and their effect was proportional to the mixing rate at the initiation of the experiment. After harvest of crop, EC of the mixture decreased further, indicating desalinization during the crop growing period for 50 days. Dry matter yield also responded to bottom ash application, showing increasing tendency with increasing bottom ash rate. Our results suggest that bottom ash can be successfully used as a soil conditioner or amendment in improving soil physical conditions of reclaimed tideland soils.

기숙사 급식 품질 만족도와 주관적 삶의 질의 관련성 평가

최미경(Mi Kyung Choi),최소희(So Hee Choi),이송이(Song I Lee) 대한지역사회영양학회 2009 대한지역사회영양학회지 Vol.14 No.1

The purpose of this study was to identify the factors of university residence hall foodservice quality which has correlations with subjective QOL (quality of life) of target customers. A total of 176 questionnaires from students of 4 universities in Daegu, Gyeongbuk area were used for the analysis. The male students using residence hall foodservices were highly satisfied with `clean appearances of employees` (4.86±1.25) and `clean facilities` (4.79±1.26), while the degree of satisfaction with `convenient facilities` (4.50±1.20) showed the highest score with female students. Ranking analysis using Spearman`s p revealed that there were significant correlations between students` satisfactions with the dimensions of `foods and kindness of employees`, `hygiene`, `nutrition`, and `convenience` and their QOL, even though physical QOL of female students showed no significant correlation with satisfaction towards residence hall foodservices. As a conclusion, there should be efforts to improve the QOL of target customers through foodservice quality management. (Korean J Community Nutrition 14(1):114~122, 2009)

흡연자에 대한 호흡근 훈련이 폐기능에 미치는 영향

서건휘,유미라,김지윤,성영미,최형진,안송희,정다영,김미나,김민정,이송이,안동진,박찬영,김현희,Suh, Geon-Hwi,Yu, Mi-Ra,Kim, Ji-Yun,Sung, Young-Mi,Choi, Hyoung-Jin,An, Song-Hui,Jeong, Da-Young,Kim, Mi-Na,Kim, Min-Jung,Lee, Song-I,An, Dong-Jin,P 대한물리치료과학회 2012 대한물리치료과학회지 Vol.19 No.3

Purpose : The purpose of present study was to investigate pulmonary function among smokers and non-smokers, and effect on respiratory muscle training in smoker. Methods : Twenty participants were allocated into smokers group(n = 10) and non-smokers group(n = 10). Pulmonary function was measured by spirometry(Pony FX, COSMED Inc., Italy). The smoker group was compared pulmonary function before and after respiratory muscle training. Results : The results were as follows; There was significant difference on PEF, FEV1/FVC%, FEF25~75%, MEF75% and MEF50% among smoker and non-smokers(p<.05). But, there was not significantly difference after intervention in smokers. Conclusion : The present study found that smoker decreased pulmonary function than non-smokers.