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      • KCI등재

        Regulatory Effect of Inflammatory Reaction by Anglicae Dahuricae Radix

        박종하,최현주,권영미,신병철,권영달,송영선 한의병리학회 2004 동의생리병리학회지 Vol.18 No.6

        Anglicae dahuricae Radix (ADR), the dried roots of Angelica Dahurica Benth et Hook (Umbelliferae), is a traditional herbal medicine used to treat colds, headache, skin diseases such as acne and possess analgesic, antipyretic and drainage effects. In the present study, the author evaluated the effect of ADR on regulation of inflammatory reaction. ADR reduced the ear-swelling responses derived from compound 48/80 in dose-dependent manner significantly. ADR inhibited the PMA plus A23187-induced productions of IL (Interleukin)-8, IL-1β, granulocyte macrophage-colony stimulating factor (GM-CSF) and tumor necrosis factor (TNF)-α from human mast cells (HMC)-1. In addition, ADR blocked PMA plus A23187-induced ERK1/2 phosphorylation. I suggest that ADR regulates inflammatory reaction through inhibition of inflammatory cytokines such as IL-8, IL-1β and GM-CSF.

      • KCI등재

        급성 세포성 이식거부반응을 동반한 이식신의 면역 관련 단백의 발현 양상

        박종하,변승운,유은실,박수길,한덕종,조영미 대한병리학회 2007 Journal of Pathology and Translational Medicine Vol.41 No.1

        Background : We wanted to find an adjunctive marker(s) in renal allograft biopsies for predicting acute cellular rejection (ACR), and so the expression patterns of immune-related molecules were compared between ACR, borderline ACR and non-ACR cases. Methods : The expression patterns of Fas ligand (FasL), HLA-DR, granzyme B, caspase-3, CD56, interferon stimulated growth factor-3 (ISGF-3), and CD53 were assessed via immunohistochemical study in 75 allograft biopsies from patients with ACR (n=19), borderline ACR (n=22), and non-ACR (n=34). Results : Compared to those of the non-ACR group, the ACR group revealed an elevated number of FasL positive interstitial inflammatory cells, HLA-DR positive tubular inflammatory cells, cytoplasmic caspase-3 positive tubular epithelial cells, granzyme B positive interstitial mononuclear inflammatory cells and CD53 positive interstitial inflammatory cells. The expression patterns of the borderline ACR group were similar to those of non-ACR group, except for the intensity of FasL in the tubular epithelial cells. Conclusions : Immunohistochemical investigations of the adjunctive markers FasL, HLA-DR, granzyme B, caspase-3 and CD56 can be useful for making the diagnosis of ACR.

      • KCI등재

        A Study on the Discretion of Juvenile Waiver in the US and its Implications

        박종하 원광대학교 경찰학연구소 2015 경찰학논총 Vol.10 No.3

        Discretion has proven to be a substantial component of the criminal justice system. Therefore, there is a general understanding that discretion cannot be prevented. Consequently, discretion should be monitored as to allow for the best benefit to society, especially within the area of juvenile waiver into the adult criminal justice system. This study will be to examine how the U.S. system applies discretion in juvenile cases and how that can be applied to a South Korean context. With the use of prior literature research concerning juvenile waiver, this study aims to examine the current juvenile waiver system in the United States through the discussion of early intentions of juvenile waiver, current types presented in the U.S., and influencing factors that increase the likelihood of transfer. Upon review, future suggestions for improvement will be determined with a rehabilitative approach. First, solid data collection is integral in the understanding and prevention of discretionary abuse. Most importantly, clear and consistent sampling procedures are needed. Second, a functional application of discretion should be established, integrating the findings from various disciplines to reduce errors. Then this knowledge should be circulated for the criminal justice practitioners. Third, prior stagnant or detrimental statutes or policies should be re-visited and revised based on a new understanding of data. Fourth, more discretion should be established through the implementation of reverse waiver provisions, serving to minimize error and ensure that offender's rights are maintained during sanctioning. As improvements are made, a secondary objective of this study will be to implement these paradigms into a South Korean context, where discretion currently falls into the hands of judges and prosecutors, primarily. Utilization in such a society will ultimately increase the level of functional discretion. Implications are discussed.

      • 분할 췌장을 동반하지 않은 환자에서 부유두를 통한 내시경 시술로 치료한 췌액 유출

        박종하,최정준,표성희,정진욱,김성두,손현영,이상수,서동완,이성구,박도현,김명환,송문희 대한소화기내시경학회 2004 Clinical Endoscopy Vol.28 No.5

        Endoscopic treatment has been performed in a variety of pancreatic ductal diseases such as stones, strictures, sphincter stenosis, and ductal disruption and is known to be an effective therapy in some patients. Endoscopic treatment through the minor papilla is frequently done in patients with pancreas divisum. Few data are, however, available concerning endoscopic minor papilla interventions in patients without pancreas divisum but with difficult access to the main pancreatic duct at the major duodenal papilla. We present a 49-year-old man, who had pancreatic ductal leak caused by previous pancreatic surgery. He was treated by endoscopic naso-pancreatic drainage and pancreatic ductal stenting through the minor papilla, so called pancreatic rendezvous technique. Follow- up ductography after two-weeks of naso-pancreatic drainage showed no leak. This case shows that minor papillar orifice could be an alternative access for therapeutic endoscopic intervention in a patient with traumatic pancreatic ductal leak without pancreas divisum. 최근 췌관 결석, 췌관 협착, 췌관 폐쇄, 췌관 손상 등의 다양한 췌장 질환에서 내시경을 이용한 치료가 활발히 시행되고 있으며, 일부에서는 그 효과가 입증되고 있다. 정상적인 해부학 구조를 가진 경우 치료 내시경 시술은 주유두를 통해 이루어진다. 분할췌장이 있는 환자에 있어서 부유두를 통한 내시경 치료는 이미 잘 알려져 있으나, 정상 해부학적 췌장 구조를 가지면서 주유두를 통한 주췌관으로의 진입이 어려운 환자에서 부유두를 통한 내시경 시술의 가능성이나 유용성에 관한 보고는 매우 드문 실정이다. 이에 저자들은 췌장의 양성 낭성종양 적출술 시행 후 발생한 췌관 손상으로 췌액 유출이 있는 환자에서, 주유두를 통한 치료 내시경 시술이 용이하지 않아 부유두를 통한 내시경 경비 췌관 배액술과 췌관 스텐트 삽입술로 췌액 유출을 치료하였던 증례를 보고하는 바이다.

      • Cds簿膜의 結晶構造 및 電氣的 特性

        朴鍾夏,朴福男 조선대학교 원자력연구소 1983 原子力硏究 Vol.3 No.-

        CdS thin films were deposited by chemical bath deposition method. X-ray diffraction patterns of CdS thin films with various temperature (300℃, 350℃, 400℃) and annealing time (30min, 60min, 90min, 120min) were obtained rotating Bragg angle 2θ (from 20˚to 60˚ by X-ray diffractometer. The CdS thin films have simple cubic structure with lattice constant 5.818A and polycrystalline with crystal orientation (111), (220) and (311). Van der Pauw's method was used for measuring the Hall effect : Specific resistivity, Hall coefficient, Hall mobility and carrier concentration of 350℃ annealed CdS thin films in the air for 120min, were found to be 3.12 X 10^5Ω㎝ 1.56 X 10^4㎤/coul, 5㎠/volt.sec, 4.7 X 10^14/㎤, respectively.

      • KCI등재

        Stainless steel crown 순면위에 레진피복을 이용한 전치부 심미적 수복

        안수현,김재곤,백병주,박종하 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.4

        Despite dentistry's attempts to improve the dental health of the public and to minimize the effects of caries, many children still present with extensive destruction of primary anterior teeth. One of dentistry's most challenging tasks is to repair these teeth with restoration which are durable, retentive, and esthetic. Esthetic restoration can often be achieved with polycarbonate crowns, strip crowns, conventional S-S crowns, open-faced S-S crowns, commercially veneered S-S crowns. But, all of these have limitation. Advances in restorative materials and metal-bonding procedures have made possible new restorative techniques that combine the advantages of S-S crowns with the cosmetics of composite restoration methods. The described technique of bonding composite to trimmed and fitted S-S crowns offers many advantages over other techniques currently used to restore primary anterior teeth. 1. If S-S crowns are accurate trimmed and contoured, good retention of crowns is achieved. 2. The patient time required is similar to that of conventional S-S crowns. 3. Good esthetics and high bond strengths are achieved. 4. It is possible to use this veneering technique intraorally on crowns that have fractured veneers.

      • KCI등재

        잇솔질 마모 처리한 불소방출성 수복재의 특성

        박종하,백병주,김재곤,양연미 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

        불소는 항우식 작용을 보이므로 치아의 우식예방을 고려한 진료가 이루어지면서 치면에 불화물을 도포하거나 불소 함유 구강세정액을 사용하거나 불소방출성의 수복재료를 적용하거나 하는 등의 우식억제 방법이 치과임상에서 빈번하게 적용되고 있다. 이에 본 연구는 불소 방출을 보이는 수복재료의 잇솔질 후 불소방출과 잇솔질로 인한 표면조도의 변화를 조사하기 위해 시행되었다. 7종의 불소를 방출하는 수복재료로 Fuji Ⅱ LC Improved: FL, Compoglass F: CG, Dyract AP: DR, F2000: FT, Ariston: AT, Tetric: TR, 그리고 Gradia: GD를 연구재료로 사용하였다. 불소 방출은 10,000회의 잇솔질을 시행한 후 10일 동안의 방출량을 측정하였고, 표면조도는 40,000회의 잇솔질 후 중심선평균거칠기 Ra와 최대거칠기 Ry를 측정하였으며, 마모면은 주사전자현미경으로 관찰하였다 잇솔질 후의 불소 방출량과 표면 관찰로부터 다음과 같은 결론을 얻었다. 1. 불소방출은 AT군, FL군 및 CF군의 경우에는 초기단계에 다량의 급격한 방출을 보인 후 상대적으로 낮으면서도 지속적인 방출 양상을 보였지만, 나머지 시험의 경우에는 초기단계로부터 낮으면서도 지속적인 방출을 보였다. 2. 불소방출은 약 40일 경과 후 안정적인 방출 양상을 나타냈으며, Tukey 분석 결과, AT군, 레진강화 GIC의 FL군, 콤포머군 전부 및 불소방출성 콤포짓트 레진의 GD군과 TC군 사이에서 통계학적으로 방출량의 유의한 차이를 보였다(p<0.05). 3. 표면조도는 FT군에서 가장 크고 CF군에서 가장 작은 값을 보였으며, Tukey 분석 결과, FT군, AL군 및 FL군과 TC군, DR군, GD군 및 CF군 사이에서 통계학적으로 유의한 차이를 보였다(P<0.05). The objectives of this study were to evaluate the fluoride release and the change of surface roughness of fluoride releasing restorative materials after toothbrush-dentifrice abrasion. Seven commercially available fluoride releasing restorative materials (Fuji Ⅱ LC Improved: FL, Compoglass F: CG, Dyract AP: DR, F2000: FT, Ariston: AT, Tetric: TR, and Gradia: GD) were selected as experimental materials. The results obtained were summarized as follows: 1. The AT, FL, and CF groups produce an initially large burst of fluoride release and comparatively low but continuous release of fluoride. But other groups produce no initial burst of fluoride and levels of release remain relatively constant. 2. The rate of fluoride release remains steady state after 40 days. The results of Tukey's test (P<.05), the fluoride release showed the order of decreasing rank as follows: AT > FL > compomers > TC and GD. 3. The surface roughness indicated that the highest value was observed in the FT group and the lowest value was observed in the CF group. The surface roughness of Tukey's test showed the significant differences between groups of FT, AT and FL and groups of CF, DR, GD and TC (P<0.05).

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