악관절 강직증에 관한 임상적 연구

민병일,송민석 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.1

Temporomandibular joint ankylosis is the movemental obstacle of mandible which depend on proliferation of bony or fibrous tissue in temporomandibular joint structure by various causes. In order to treat this, various surgical methods have been performed, but no operative methods have been produced consistently successful results. This research has been performed to the patients who had been operated due to temporomandibular joint ankylosis by studying classification, cause, onset, duration, anesthesia and treatment method, symptom, change of mouth opening, complication through medical record, X-ray, follow-up for being a help to proper selection of treatment method and evaluation of prognosis. The author obtained the following results by analyzing 44 cases among patients who had been operated due to temporomandibular joint ankylosis during 8 year hospitalization from 1986 to 1993 in Dept. of Oral & Maxillofacial Surgery of Seoul National University Hospital. 1. The occurrence was in the order of below 10, 20's, 10's, 30's. The average of occurrence was 12.95. Illness period was 50.0% within 10 years and 50% beyond 10 years. The average period of illness was 13.33 years. 2. Trauma occupied 54.5% of causes and inflammation occupied 45.5%. Men had more occurrences due to trauma and there was no difference in case of inflammation. 3. In nasotracheal intubations for general anesthesia, the cases of using fiberoptic larygoscope occupied 40.9%, direct or blind nasotracheal intubation occupied 40.9% and the cases of using tracheostomy occupied 18.2%. 4. In operative approaching methods, submandibular & preauricular approach were mainly applied, and in operative methods, high condylectomy(Group I) occupied 11.4%, arthroplasty without interpositional material following condylectomy or gap ostectomy(Group Ⅱ) occupied 11.4%, with interpositional material following high condylectomy (Group Ⅲ) occupied 40.9%, and using condylar reconstruction following condylectomy or gap ostectomy(Group Ⅳ) occupied 36.6%. 5. In change of mouth opening reformed after surgery, Group Ⅲ showed the best result of average 23.5mm, Group Ⅳ showed 16.3mm, Group Ⅰ showed 14.9mm and Group Ⅱ showed 10.2mm of reformation. Summarizing the results as written above, it is considered that early treatment is important as soon as possible in Temporomandibular joint ankylosis. It is recommended in surgical method what can lead to postoperative early movement maintaining anatomaical & functional form, and then the development of various surgical methods will be requested.

Exploratory evaluation of the role of cardiac troponin on the clinical outcome of patients visiting emergency department with or without chronic kidney disease

송민석,강은진,김태림,박종은,이건탁,윤희,황성연,차원철,신태건,심민섭,조익준,최진호 대한응급의학회 2022 대한응급의학회지 Vol.32 No.6

Objective: Elevated levels of cardiac troponin in chronic kidney disease (CKD) patients admitted to the emergency department (ED) is not well understood and is often ignored. This study aimed to investigate the impact of cardiac troponin I (TnI) levels on the clinical outcome of patients visiting the ED with or without CKD. Methods: In this retrospective single-center cohort study, we enrolled patients visiting the ED without a diagnosis of coronary artery disease (CAD). Elevated cardiac TnI was defined as being ≥99th percentile of the normal population (Siemens ADVIA Centaur TnI-Ultra≥0.040 ng/mL). The clinical outcomes of patients with CKD stage≤2 and CKD stage ≥3 were compared. The primary endpoint was the 180-day all-cause death, including cardiovascular and non-cardiovascular deaths. Results: Among a total of 30,472 patients (median age, 61 years; male sex, 54.3%), elevated TnI was found in 4,377 patients (14.4%). There were 3,634 deaths (11.9%) including 584 cardiovascular (1.9%) and 3,050 non-cardiovascular deaths (10.0%). The risk of all-cause death increased in patients with elevated TnI in both CKD stage≤2 (hazard ratio [HR], 2.1; 95% confidence interval [CI], 1.9-2.3) and CKD stage≥3 (HR, 1.5; 95% CI, 1.4-1.7), and so did the risks of cardiovascular and non-cardiovascular death (HR, 1.2-4.7) (P<0.05, all). The association of elevated TnI with death risk was consistent in multivariate analyses and in most clinical subgroup analyses. Conclusion: Elevated TnI was associated with higher 180-day mortality irrespective of renal function among patients visiting the ED without documented CAD. CKD patients visiting the ED with elevated TnI may warrant additional evaluation or careful follow-up even without the presence of CAD.

유럽의 발효육제품 기술 개발 동향

송민석,강기문,박종세,유근주,정동순,사공헌구,최지훈,Song, Min Seok,Kang, Ki Moon,Park, Jong Se,Ryu, Geun Joo,Jeong, Dong Soon,Sagong, Hun Gu,Choi, Ji Hun 한국축산식품학회 2017 축산식품과학과 산업 Vol.6 No.1

Evaluation of the Efficacy of a Pre-pandemic H5N1 Vaccine (MG1109) in Mouse and Ferret Models

송민석,문호진,권혁일,Philippe Noriel Q. Pascua,이준한,백윤희,우규진,최주희,이상호,유현승,오인경,윤엽,노종복,성문희,홍승표,김철중,최영기 한국미생물학회 2012 The journal of microbiology Vol.50 No.3

The threat of a highly pathogenic avian influenza (HPAI) H5N1 virus causing the next pandemic remains a major concern. In this study, we evaluated the immunogenicity and efficacy of an inactivated whole-virus H5N1 pre-pandemic vaccine (MG1109) formulated by Green Cross Co., Ltd containing the hemagglutinin (HA) and neuraminidase (NA) genes of the clade 1 A/Vietnam/1194/04 virus in the backbone of A/Puerto Rico/8/34 (RgVietNam/04xPR8/34). Administration of the MG1109 vaccine (2-doses) in mice and ferrets elicited high HI and SN titers in a dose-dependent manner against the homologous (RgVietNam/04xPR8/34) and various heterologous H5N1 strai(RgKor/W149/06xPR8/34,RgCambodia/ 04xPR8/34,RgGuangxi/05xPR8/34), including a heterosubtypic H5N2 (A/Aquatic bird/orea/W81/05) virus. However, efficient cross-reactivity was not observed against heterosubtypic H9N2 (A/Ck/Korea/H0802/08) and H1N1 (PR/8/34) viruses. Mice immunized with 1.9 μg HA/dose of MG1109 were completely protected from lethal challenge with heterologous wild-type HPAI H5N1 A/EM/Korea/W149/06 (clade 2.2) and mouse-adapted H5N2 viruses. Furthermore, ferrets administered at least 3.8 μg HA/dose efficiently suppressed virus growth in the upper respiratory tract and lungs. Vaccinated mice and ferrets also demonstrated attenuation of clinical disease signs and limited virus spread to other organs. Thus, this vaccine provided immunogenic responses in mouse and ferret models even against challenge with heterologous HPAI H5N1 and H5N2 viruses. Since the specific strain of HPAI H5N1 virus that would potentially cause the next outbreak is unknown, pre-pandemic vaccine preparation that could provide crossprotection against various H5 strains could be a useful approach in the selection of promising candidate vaccines in the future.

제42차 춘계학술대회 : 포스터 연제 ; 혈전의 경피배출을 보인 혈전성 혈관각화종 2예

송민석,최영식,방동식 대한피부과학회 1990 초록집 Vol.28 No.20

비정형 물체 조작을 위한 VR 원격조종 시스템 개발과 데이터셋 수집

송민석,박봉경,박대형 제어로봇시스템학회 2024 제어로봇시스템학회 국내학술대회 논문집 Vol.2024 No.7

사회복지시설 평가제도의 융합모형

송민석 한국융합학회 2015 한국융합학회논문지 Vol.6 No.5

사회복지시설은 지역주민의 복지욕구에 적합한 서비스의 자원개발과 전달체계를 국가로부터 위임받아 국 민에게 전문적인 사회복지서비스 제공을 위해 시설의 합리적이고 효율적인 시설운영과 효과적인 서비스전달 등에 대한 사회적 책임의식을 가진다. 지금까지 사회복지사업법 규정에 의한 제5차에 걸친 평가는 사회복지시설 운영의 효율성과 책임성을 제고하는 동시에 합리적이고 체계적인 운영방향을 제시하여 사회복지시설의 균형적 발전과 선진 화를 위한 중요한 토대를 마련하였다. 그러나 사회복지시설 평가의 문제점에 대해서도 지속적으로 제기되어 온 것도 사실이다. 따라서 본 연구에서는 사회복지시설에 대한 사회적 요구에 부응할 수 있는 평가체계가 갖추어야 할 기준 과 개선방안을 도출함으로써 시설이용자들의 복지를 통한 삶의 질을 향상시킬 수 있는 융합모형을 제시하고자 한다. The social welfare facilities are trusted by the government for the development of appropriate welfare services and their delivery systems. They aim to provide people with professional social welfare services and, for this purpose, they develop ways to effectively operate facilities and to deliver the services efficiently. So far, the five consecutive evaluations based on the Social Services Act have suggested the effective and systematic ways of operating social welfare facilities. Through these efforts, they established an important basis for the balanced development and further advancement of social welfare facilities. Nevertheless, people have continually pointed out problems concerning the evaluation system of social welfare facilities. Accordingly, these problems have the necessity of investigation for reformed directions by means of effective control and evaluation system for the operation of social welfare facilities. Therefore, this study aims to suggest convergence models for improving the social welfare facilities evaluation system.

비즈니스 프로세스 수행자들의 Social Network Mining에 대한 연구

송민석,W.M.P. van der Aalst,최인준 대한산업공학회 2004 대한산업공학회 춘계학술대회논문집 Vol.2004 No.2

國內企業의 對北韓 役資에 관한 硏究

宋珉錫 건국대학교 1995 대학원 학술논문집 Vol.41 No.-

The purpose of this study is to explain the present conditions and problems of the investment in North Korea of Domestic firms, and further explore the activationary plan of the investment in North Korea Domestic firms. Reflecting on the thirty years which have passed since Korea was divided, it is clear that since 1953 the economy of the two Koreas has undergone may changes under their two different social and economic systems, and that the two economies will continue to follow different courses in the future. North Korea has acted a passive attitude toward the foreign trade, because she has pursued the autarchic economic development policy on the basis of the socialistic economic system as yet. Therefore, she has congnized that it is impossible to develop the economy by the principle of the self-revival what is to say a self-support national economy and the closed trade system which has been excuted in the countries centering on the Communistic Area. So she had to change to the foreign trade system as the open system by transforming the autarchic system they hierto adhered to. This brief overview of recent developments attempts to compare various economic indicators and thus show how rapidly the Congress. This remains a principal government policy down to the present day. Judging from these circumstances as mentioned above, it can be suggested that the economy of North Korea holds certain structural defects which will eventually bring aboutq a transformation from the presently closed society to an open one. Any dramatic changes in the basic policy guidelines which have been followed to date, however, would mean the abandonment of the fundamental ideology and the political posture which supports the present system. As a result, it seems probable that the 1990s will be a period of expand bilateral partnership in the areas of economy between South and North Korea.

구조보존규칙으로서의 영어 비음동화:[η]에 대한 해결책

宋旼錫 관동대학교 1995 關大論文集 Vol.23 No.2

The velar nasal [ŋ] is an allophone of /n/ in English. This fact is evidenced by distributional restrictions. That is, [ŋ] always appears before /g/ or /k/, while /m/ and /n/ occur freely. But in the theory of Lexical Phonology, the English Nasal Assimilation which derives the velar nasal [ŋ] must be a phonological rule which applies in the lexicon. For this rule must precede the morphological process suffixing '-er', as shown in the examples of "sing" and "singer" ("singer" is pronounced as [siŋ( )r], not as [siŋg( )r]). On the other hand, a lexical rule must be structure-preserving in the sense that if a feature is not distinctive in any context it may not play any role in the lexical phonology(Kiparsky, 1984). With regard to this principle of Structure Preservation, the above nasal assimilation has a problem because this process is not structure-preserving but must be lexical. To solve this problem, Borowsky(1986) says that the above nasal assimilation is applied at level 2 and that the principle of Structure Preservation turns off at level 2. This is an ad hoc solution. If this solution is accepted, the word of "concord" must be derived at level 2 while the words of "combine" and "concern" are derived at level 1 (independently motivated). This paper tries to solve this problem in the standpoint of the feature geometry theory. In the feature geometry, the process of spreading to an underspecified target is interpreted as structure-preserving. And the above nasal assimilation is a process of spreading to an underspecified target because the place feature of the phoneme /n/ is underspecified in the underlying representation. In the result, the English nasal assimilation is a structure-preserving process and can apply freely in the lexicon. As another desirable result, we can say that all lexical phonology is structure-preserving.